A comparison of moxifloxacin and levofloxacin topical prophylaxis in a fluoroquinolone-resistant Staphylococcus aureus rabbit model

Japanese Journal of Ophthalmology

Volumn 52, Issue 3, 2008, Pages 211-216

  Kowalski, Regis P ^a,b   Romanowski, Eric G ^a,b   Mah, Francis S ^a,b   Sasaki, Hiroshi ^c   Fukuda, Masamichi ^c   Gordon, Y J ^a,b  

^a UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

^b University of Pittsburgh School of Medicine   (United States)

^c KANAZAWA MEDICAL UNIVERSITY   (Japan)

Author keywords

Endophthalmitis; Levofloxacin; Moxifloxacin; Rabbit model; Staphylococcus aureus

Indexed keywords

LEVOFLOXACIN; MOXIFLOXACIN; SODIUM CHLORIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBIOTIC PROPHYLAXIS; ARTICLE; BACTERIAL COUNT; BACTERIUM CULTURE; CONTROLLED STUDY; ENDOPHTHALMITIS; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; NONHUMAN; PRIORITY JOURNAL; PROVOCATION TEST; RABBIT; SLIT LAMP;

ADMINISTRATION, TOPICAL; ANIMALS; ANTI-BACTERIAL AGENTS; AQUEOUS HUMOR; AZA COMPOUNDS; COLONY COUNT, MICROBIAL; DISEASE MODELS, ANIMAL; DRUG RESISTANCE, MULTIPLE, BACTERIAL; ENDOPHTHALMITIS; EYE INFECTIONS, BACTERIAL; FLUOROQUINOLONES; METHICILLIN; OFLOXACIN; QUINOLINES; RABBITS; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCUS AUREUS; VITREOUS BODY;

EID: 48249145845     PISSN: 00215155     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10384-008-0530-1     Document Type: Article

References (10)

1. D.H. Kim W.J. Stark T.P. O'Brien J.D. Dick 2005 Aqueous penetration and biological activity of moxifloxacin 0.5% ophthalmic solution and gatifloxacin 0.3% solution in cataract surgery patients Ophthalmology 112 1992 1996
2. R. Solomon E.D. Donnenfeld H.D. Perry 2005 Penetration of topically applied gatifloxacin 0.3%, moxifloxacin 0.5%, and ciprofloxacin 0.3% into the aqueous humor Ophthalmology 112 466 469
3. R.S. Wagner M.B. Abelson A. Shapiro G. Torkildesn 2005 Evaluation of moxifloxacin, ciprofloxacin, gatifloxacin, ofloxacin, and levofloxacin concentrations in human conjunctival tissue Arch Ophthalmol 123 1282 1283
4. th generation fluoroquinolones: New weapons in the arsenal of ophthalmic antibiotics Am J Ophthalmol 133 4 463 466
5. R.P. Kowalski D.K. Dhaliwal L.M. Karenchak 2003 Gatifloxacin and moxifloxacin: an in vitro susceptibility comparison to levofloxacin, ciprofloxacin, and ofloxacin using bacterial keratitis isolates Am J Ophthalmol 136 500 505
6. R.P. Kowalski K.A. Yates E.G. Romanowski L.M. Karenchak F.S. Mah J.S. Gordon 2005 An Ophthalmologist's guide to understanding antibiotic susceptibility and minimum inhibitory concentration (MIC) data Ophthalmology 112 1987 1991
7. R.P. Kowalski E.G. Romanowski F.S. Mah K.A. Yates Y.J. Gordon 2004 Topical prophylaxis with moxifloxacin prevents endophthalmitis in a rabbit model Am J Ophthalmol 138 33 37
8. L.E. Fernandez de Castro H.P. Sandoval L.R. Bartholomew D.T. Vroman K.D. Solomon 2006 Prevention of Staphylococcus aureus endophthalmitis with topical gatifloxacin in a rabbit prophylaxis model J Ocular Pharmacol Ther 22 132 138
9. E.G. Romanowski F.S. Mah K.A. Yates R.P. Kowalski Y.J. Gordon 2005 The successful treatment of gatifloxacin-resistant Staphylococcus aureus keratitis with Zymar (gatifloxacin 0.3%) in a NZW rabbit model Am J Ophthalmol 139 867 877
10. M. Fukuda H. Sasaki 2007 Intraocular penetration of moxifloxacin ophthalmic solution in rabbit eyes Invest Ophthalmol Vis Sci 48 3920