Antibodies against pancreatic ribonuclease A hydrolyze RNA and DNA

International Immunology

Volumn 20, Issue 8, 2008, Pages 1031-1040

  Krasnorutskii, Michael A ^a   Buneva, Valentina N ^a   Nevinsky, Georgy A ^a  

^a INSTITUTE OF CHEMICAL BIOLOGY AND FUNDAMENTAL MEDICINE   (Russian Federation)

Author keywords

Abzymes against pancreatic RNase; RNA and DNA hydrolysis

Indexed keywords

AUTOANTIBODY; BOVINE SERUM ALBUMIN; CELLULOSE; DEOXYRIBONUCLEASE I; IMMUNOGLOBULIN G; IMMUNOGLOBULIN G ANTIBODY; NUCLEIC ACID; PANCREAS ENZYME; POLYCLONAL ANTIBODY; RIBONUCLEASE A; SEPHAROSE;

AFFINITY CHROMATOGRAPHY; ANIMAL EXPERIMENT; ANTIBODY PRODUCTION; ARTICLE; CATALYSIS; CONTROLLED STUDY; DNA DETERMINATION; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME BINDING; ENZYME INACTIVATION; IMMUNE RESPONSE; IMMUNIZATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN HYDROLYSIS; RNA ANALYSIS;

ANIMALS; ANTIBODIES, CATALYTIC; ANTIBODY SPECIFICITY; BINDING SITES, ANTIBODY; CATTLE; CHROMATOGRAPHY, AFFINITY; DNA; HUMANS; HYDROLYSIS; IMMUNIZATION, SECONDARY; NUCLEIC ACID CONFORMATION; PANCREAS; RABBITS; RIBONUCLEASE, PANCREATIC; RNA; SERUM ALBUMIN, BOVINE;

EID: 48249122263     PISSN: 09538178     EISSN: 14602377     Source Type: Journal    
DOI: 10.1093/intimm/dxn061     Document Type: Article

References (49)

1. Keinan, E, eds., 2005. Catalytic Antibodies, p. 1. Wiley-VCH Verlag GmbH and Co, KgaA, Weinheim, Germany.
2. Nevinsky, G. A. and Buneva, V. N. 2002. Human catalytic RNA-and DNA-hydrolyzing antibodies. J. Immunol. Methods 269:235.
3. Nevinsky, G. A., Favorova, O. O. and Buneva, V. N. 2002. Natural catalytic antibodies - new characters in the protein repertoire. In Golemis, E., ed., Protein-Protein Interactions; A Molecular Cloning Manual, p. 523. Cold Spring Harbor Laboratory Press, New York, NY.
4. Nevinsky, G. A. and Buneva, V. N. 2003. Catalytic antibodies in healthy humans and patients with autoimmune and viral pathologies. J. Cell. Mol. Med. 7:265.
5. Nevinsky, G. A. and Buneva, V. N. 2004. Natural catalytic antibodies - abzymes. In Keinan, E., ed., Catalytic Antibodies, p. 503. VCH-Wiley Press, Weinheim, Germany.
6. Paul, S., Volle, D. J., Beach, C. M., Johnson, D. R., Powell, M. J. and Massey, R. J. 1989. Catalytic hydrolysis of vasoactive intestinal peptide by human autoantibody. Science 244:1158.
7. Shuster, A. M., Gololobov, G. V., Kvashuk, O. A., Bogomolova, A. E., Smirnov, I. V. and Gabibov, A. G. 1992. DNA hydrolyzing autoantibodies. Science 256:665.
8. Kalaga, R., Li, L., O'Dell, J. R. and Paul, S. 1995. Unexpected presence of polyreactive catalytic antibodies in IgG from unimmunized donors and decreased levels in rheumatoid arthritis. J. Immunol. 155:2695.
9. Savel'iev, A. N., Ivanen, D. R., Kulminskaya, A. A. et al. 2003. Amylolytic activity of IgM and IgG antibodies from patients with multiple sclerosis. Immunol. Lett. 86:291.
10. Baranovsky, A. G., Matushin, V. G., Vlassov, A. V. et al. 1997. DNA-and RNA-hydrolyzing antibodies from the blood of patients with various forms of viral hepatitis. Biochemistry (Mosc.) 62:1358.
11. Baranovskii, A. G., Kanyshkova, T G., Mogelnitskii,. A. S. et al. 1998. Polyclonal antibodies from blood and cerebrospinal fluid of patients with multiple sclerosis effectively hydrolyse DNA and RNA. Biochemistry (Mosc.) 63:1239.
12. Founel, S. and Muller, S. 2002. Antinucleosome antibodies and T-cell response in systemic lupus erythematosus. Ann. Med. Interne (Paris 153:513.
13. Avalle, B., Zanin, V., Thomas, D. and Friboulet, A. 1998. Antibody catalysis based on functional mimicry. Appl. Biochem. Biotechnol. 75:3.
14. Avalle, B., Friboulet, A. and Thomas, D. 1998. Screening of inhibitory monoclonal antibodies. A critical step for producing anti-idiotypic catalytic antibodies. Ann. N. Y. Acad. Sci. 864:118.
15. Izadyar, L., Friboulet, A., Remy, M. H., Roseto, A. and Thomas, D. 1993. Monoclonal anti-idiotypic antibodies as functional internal images of enzyme active sites: Production of a catalytic antibody with a cholinesterase activity. Proc. Natl Acad. Sci. USA. 90:8876.
16. Kolesnikov, A. V., Kozyr, A. V., Alexandrova, E. S. et al. 2000. Enzyme mimicry by the antiidiotypic antibody approach. Proc. Natl Acad. Sci. USA. 97:13526.
17. Hu, R., Xie, G. Y., Zhang, X., Guo, Z. Q. and Jin, S. 1998. Production and characterization of monoclonal anti-idiotypic antibody exhibiting a catalytic activity similar to carboxypeptidase A. J. Biotechnol. 61:109.
18. Friboulet, A., Izadyar, L., Avalle, B., Roseto, A. and Thomas, D. 1994. Abzyme generation using an anti-idiotypic antibody as the "internal image" of an enzyme active site. Appl. Biochem. Biotechnol. 47:229.
19. Debat, H., Avalle, B., Chose, O., Sarde, C.-O., Friboulet, A. and Thomas, D. 2001. Overpassing an aberrant V(kappa) gene to sequence an anti-idiotypic abzyme with (beta)-lactamase-like activity that could have a linkage with autoimmune diseases. FASEB J. 15:815.
20. Hifumi, E., Morihara, F., Hatiuchi, K., Okuda, T., Nishizono, a and Uda, T. 2008. Catalytic features and eradication ability of antibody light-chain UA15-L against Helicobacter pylori. J. Biol. Chem. 283:899.
21. Bronshtein, I. B., Shuster, A. M., Gololobov, G. V. et al. 1992. DNA-specific antiidiotypic antibodies in the sera of patients with autoimmune diseases. FEBS Lett. 314:259.
22. Crespeau, H., Laouar, A. and Rochu, D. 1994. Polyclonal DNase abzyme produced by anti-idiotypic internal image method. C. R. Acad. Sci III 317:819.
23. Andrievskaya, O. A., Buneva, V. N., Naumov, V. A. and Nevinsky, G. A. 2000. Catalytic heterogeneity of polyclonal RNA-hydrolyzing IgM from sera of patients with lupus erythematosus. Med. Sci. Monit. 6:460.
24. Andrievskaya, O. A., Buneva, V. N., Baranovskii, A. G. et al. 2002. Catalytic diversity of polyclonal RNA-hydrolyzing IgG antibodies from the sera of patients with systemic lupus erythematosus. Immunol. Lett. 81:191.
25. Buneva, V. N., Kanyshkova, T G., Vlassov, A. V. et al. 1998. Catalytic DNA- and RNA-hydrolyzing antibodies from milk of healthy human mothers. Appl. Biochem. Biotechnol. 75:63.
26. Nevinsky, G. A., Kanyshkova, T. G., Semenov, D. V., Vlassov, A. V., Gal'vita, A. V. and Buneva, V. N. 2000. Secretory immunoglobulin A from healthy human mothers' milk catalyzes nucleic acid hydrolysis. Appl. Biochem. Biotechnol. 83:115.
27. Andrievskaia, O. A., Kanyshkova, T. G., Iamkovoi, V. I., Buneva, V. N. and Nevinskii, G. A. 1997. Monoclonal antibodies to DNA hydrolyze RNA better than DNA. Dokl. Akad. Nauk. 355:401.
28. Crook, E. M., Mathias, A. P. and Rabin, B. R. 1960. Spectrophotometric assay of bovine pancreatic ribonuclease by the use of cytidine 2′:3′-phosphate. Biochem. J. 74:234.
29. Irie, M., Mikami, F., Monma, K. et al. 1984. Kinetic studies on the cleavage of oligouridilic acids and polyU by bovine pancreatic ribonuclease A. J. Biochem. 96:89.
30. Fisher, B. M., Grilley, J. E. and Raines, R. T. 1998. A New remote subsite in ribonuclease A. J. Biol. Chem. 273:34134.
31. Fersht, A. 1985. Enzyme Structure and Mechanism, 2nd edn. W.H. Freeman, Co., New York, NY.
32. Raz, E., Ben-Bassat, H., Davidi, T., Shlomoz, Z. and Eilat, D. 1993. Cross-reactions of anti-DNA autoantibodies with cell surface proteins. Eur. J. Immunol. 23:383.
33. Polosukhina, D. I., Kanyshkova, T., Doronin, B. M. et al. 2004. Hydrolysis of myelin basic protein by polyclonal catalytic IgGs from the sera of patients with multiple sclerosis. J. Cell. Mol. Med. 8:359.
34. Odintsova, E. S., Buneva, V. N. and Nevinsky, G. A. 2005. Casein-hydrolyzing activity of sIgA antibodies from human milk. J. Mol. Recognit. 18:413.
35. Kubota, T. 1977. Lessons from a monoclonal antibody to double-stranded DNA. J. Med. Dent. Sci. 44:37.
36. Marion, T. N., Krishan, M. R., Desai, D. D., Jou, N. T. and Tillman, D. M. 1997. Monoclonal anti-DNA antibodies: Structure, specificity, and biology. Methods 11:3.
37. Mitsuhashi, S., Saito, R., Kurashige, S. and Yamashugi, N. 1978. Ribonucleic acid in the immune response. Mol. Cell. Biochem. 20:131.
38. Gottieb, A. A. and Shwartz, R. H. 1972. Antigen-RNA interactions. Cell. Immunol. 5:341.
39. Dabelic, N. and Cices, N. 1997. Clinical importance of antinuclear antibodies. Lijec. Vjesn. 119:236.
40. Bernardi, G. 1971. Hydrolysis: Other C-N bonds, phosphate esters. In Boyer, P. D., ed., The Enzymes, p. 271. Academic Press, New York, NY.
41. Suck, D. 1994. DNA recognition by DNase I. J. Mol. Recognit. 7:65.
42. Akagi, K., Murai, K., Hirao, N. and Yamanaka, M. 1976. Purification and properties of alkaline ribonucleases from human serum. Biochim. Biophys. Acta. 442:368.
43. Fletcher, M. C., Kuderova, A., Cygler, M. and Lee, J. S. 1998. Creation of a ribonuclease abzyme through site-directed mutagenesis. Nat. Biotechnol. 16:1065.
44. Semenov, D. V., Kanyshkova, T. G., Karotaeva, N. A. et al. 2004. Catalytic nucleotide-hydrolyzing antibodies in milk and serum of clinically healthy human mothers. Med. Sci. Monit. 10:BR23.
45. Gorbunov, D. V., Karataeva, N. A., Buneva, V. N. and Nevinsky, G. A. 2005. Lipid kinase activity of antibodies from milk of clinically healthy human mothers. Biochim. Biophys. Acta. 1735:153.
46. Karataeva, N. A., Gorbunov, D., Prokudin, I. V. et al. 2006. Human milk antibodies with polysaccharide kinase activity. Immunol. Lett. 103:58.
47. Gololobov, G. V., Chernova, E. A., Schourov, D. V., Smirnov, I. V., Kudelina, I. A. and Gabibov, A. G. 1995. Cleavage of supercoiled plasmid DNA by autoantibody Fab fragment: Application of the flow linear dichroism technique. Proc. Natl Acad. Sci. USA. 92:254.
48. Nishi, Y. 2002. Evolution of catalytic antibody repertoire in autoimmune mice. J. Immunol. Methods 269:213.
49. Tawfik, D. S., Chap, R., Green, B. S., Sela, M. and Eshhar, Z. 2002. Unexpectedly high occurrence of catalytic antibodies in MRL/lpr and SJL mice immunized with a transition-state analog: Is there a linkage to autoimmunity? Proc. Natl Acad. Sci. USA. 92:2145.