Aspartate aminotransferase-to-platelet ratio index for fibrosis and cirrhosis prediction in chronic hepatitis C patients

Brazilian Journal of Infectious Diseases

Volumn 12, Issue 1, 2008, Pages 15-19

  da Silva Jr , Roberto Gomes ^a,b   Fakhouri, Ricardo ^a   do Nascimento, Tereza Virgínia Bezerra ^a   Santos, Igor Martins ^a   Barbosa, Luciana Mendonça Morais ^a  

^a FEDERAL UNIVERSITY OF SERGIPE   (Brazil)

^b Federal University of Sergipe ^*  (Brazil)

Author keywords

APRL; Chronic hepatitis C; Cirrhosis; Fibrosis; Liver biopsy

Indexed keywords

ASPARTATE AMINOTRANSFERASE;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC VALUE; FEMALE; HEPATITIS C; HUMAN; INVASIVE PROCEDURE; LIVER BIOPSY; LIVER CIRRHOSIS; LIVER FIBROSIS; LIVER HISTOLOGY; MALE; NON INVASIVE MEASUREMENT; PREDICTION; RECEIVER OPERATING CHARACTERISTIC; THROMBOCYTE;

ADULT; AGED; ALANINE TRANSAMINASE; ASPARTATE AMINOTRANSFERASES; BIOLOGICAL MARKERS; BIOPSY; CLINICAL ENZYME TESTS; DISEASE PROGRESSION; EPIDEMIOLOGIC METHODS; FEMALE; HEPATITIS C, CHRONIC; HUMANS; LIVER CIRRHOSIS; MALE; MIDDLE AGED; PLATELET COUNT; YOUNG ADULT;

EID: 48249111838     PISSN: 14138670     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (32)

1. Choo Q.L., Kuo G., Weiner A.J., et al. Isolation of a cDNA clone derived from a blood non-A, non-B viral hepatitis genome. Science 1989; 244:359-62.
2. National Institutes of Health. Consensus Development Conference Statement: Management of Hepatitis C 2002. Gastroenterology 2002:123;2082-99.
3. Liang T.J., Reherman B., Seeff L.B., Hoofnagle J.H. Pathogenesis, natural history, treatment and prevention of hepatitis C. Ann Inter Med 2000;132:296-305.
4. Cheinquer H. Hepatites Virais Agudas e Crônicas. In: Lopes A.L. Tratado de Clínica Médica. São Paulo: Editora Roca, 2006.
5. Lauer G.M., Walker B.D. Hepatitis C virus infection. N Engl J Med 2001;345:41-52.
6. Dienstage J.L. The role of liver biopsy in chronic hepatitis C. Hepatology 2002;36:152-60.
7. Poynard T., Imbert-Bismut F., Munteanu M., et al. Overview of the diagnostic value of biochemical markers of liver fibrosis (FibroTest, HCV FibroSure) and necrosis (ActiTest) in patients with chronic hepatitis C. Comp Hepatol 2004;3:8.
8. Cadranel J.F., Rufat P., Degos F. Practices of liver biopsy in France: results of a prospective nationwide survey. For the Group of Epidemiology of the French Association for the Study of the Liver (AFEF). Hepatology 2000;32:477-81.
9. Wong J.B, Koff R.S. Watchful waiting with periodic liver biopsy versus immediate empirical therapy for histologically mild chronic hepatitis C. A cost- effectiveness analysis. Ann Intern Med 2000; 133:665-75.
10. Colloredo G, Guido M., Sonzogni A., Leandro G. Impact of liver biopsy size on histological evaluation of chronic viral hepatitis: the smaller the sample, the milder the disease. J Hepatol 2003;39:239-44.
11. Aldhal N.H, Nunes D. Evaluation of liver fibrosis: a concise review. Am J Gastroenterol 2004;99:1160-74.
12. Westin J., Lagging L.M., Wejstal R., et al. Interobserver study of liver histology using the Ishak score in patients with chronic hepatitis C virus infection. Liver 1999;19:183-7.
13. Regev A., Berho M., Jeffers L.J., et al. Sampling error and intraobserver variation in liver biopsy in patients with chronic HCV infection. Am J Gastroenterol 2002;97:2614-8.
14. Imbert-Bismut R, Ratziu V., Pieroni L., et al. Biochemical markers of liver fibrosis in patients with hepatitis C virus infection: a prospective study. Lancet 2001;357:1069-75.
15. Forns X., Ampurdanes S., Llovet J.M., et al. Identification of chronic hepatitis C patients without hepatic fibrosis by a simple predictive model. Hepatology 2002;36:986-92.
16. Wai C.T., Greenson J.K., Fontana R.J., et al. A simple noninvasive index can predict both significant fibrosis and cirrhosis in patients with chronic hepatitis C. Hepatology 2003;38:518-26.
17. Matteoni C.A., Younossi Z.M., Gramlich T., et al. Nonalcoholic fatty liver disease: a spectrum of clinical and pathological severity. Gastroenterology 1999;116:1413-19.
18. The French METAVIR Cooperative Study Group. Intraobserver and interobserver variations in liver biopsy interpretation in patients with chronic hepatitis C. Hepatology 1994;20:15-20.
19. Bourliere M., Penaranda G., Renou C., et al. Validation and comparison of indexes for fibrosis and cirrhosis prediction in chronic hepatitis C patients: proposal for a pragmatic approach classification without liver biopsies. J Viral Hepat 2006;13:659-70.
20. Sebastiani G., Vario A., Guido M., et al. Stepwise combination algorithms of non-invasive markers to diagnose significant fibrosis in chronic hepatitis C. J Hepatol 2006;44:686-93.
21. Pohl A., Behling C., Oliver D., et al. Serum aminotransferase levels and platelet counts as predictors of degree of fibrosis in chronic hepatitis C virus infection. Am J Gastroenterol 2001;96:3142-46.
22. Poynard T., Bedossa P., METAVIR and CLINIVIR cooperative study groups. Age and platelet count: a simple index for predicting the presence of histological lesions in patients with antibodies to hepatitis C virus. J Viral Hepat 1997;4:199-208.
23. Aster R. Pooling of platelets in the spleen: role in the pathogenesis of "hypersplenic" thrombocytopenia. J Clin Invest 1996; 45:645-57.
24. George J.N. Platelets. Lancet 2000;355:1531-9.
25. Kawasaki T., Takeshita A., Souda K., et al. Serum thrombopoietin levels in patients with chronic hepatitis and liver cirrhosis. Am J Gastroenterol 1999;94:1918-22.
26. Adinolfi L.E., Giordano M.G., Andreana A., et al. Hepatic fibrosis plays a central role in the pathogenesis of thrombocytopenia in patients with chronic viral hepatitis. Br J Haematol 2001;113:590-5.
27. Okuda M., Li K., Beard M.R., et al. Mitochondrial injury, oxidative stress, and antioxidant gene expression are induced by hepatitis C virus core protein. Gastroenterology 2002;122:366-75.
28. Kamimoto Y., Horiuchi S., Tanase S., Morino Y. Plasma clearance of intravenously injected aspartate aminotransferase isozymes: evidence for preferential uptake by sinusoidal liver cells. Hepatology 1985; 5:367-75.
29. Halfon P., Bacq Y., Muret A., et al. Comparison of test performance profile for blood tests. J Hepatol 2007;46:395-402.
30. Foucher J., Vergniol J., Caste'ra L., et al. Fibrosis evaluation in chronic liver diseases: comparison of Fibroscan with liver biopsy, Fibrotest, Forns score, APRI, Hyaluronan, Prothrombin time, and AST/ALT Ratio. J Hepatol 2005;42:78.
31. Lackner C., Struber G., Liegl B., et al. Comparison and validation of simple noninvasive tests for prediction of fibrosis in chronic hepatitis C. Hepatology 2005;41:1376-82.
32. Le Calvez S., Thabut D., Messous D., et al. The predictive value of fibrotest vs. APRI for the diagnosis of fibrosis in chronic hepatitis C. Hepatology 2004;39:862-3.