The role of ace gene polymorphism in the development of angioedema secondary to angiotensin converting enzyme inhibitors and angiotensin II receptor blockers

Allergologia et Immunopathologia

Volumn 36, Issue 3, 2008, Pages 134-140

  Gulec, Mustafa ^a   Caliskaner, Z ^a   Tunca, Y ^a   Ozturk, S ^a   Bozoglu, E ^a   Gul, D ^a   Erel, F ^a   Kartal, O ^a   Karaayvaz, M ^a  

^a GULHANE SCHOOL OF MEDICINE   (Turkey)

Author keywords

ACE gene polymorphism; ACE inhibitors; Angioedema

Indexed keywords

AMLODIPINE; AYRA; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CANDESARTAN; CILAZAPRIL; CONVERSYL; DELIX PLUS; DIPEPTIDYL CARBOXYPEPTIDASE; DOXAZOSIN; EKLIPS; ENALAPRIL; HYDROCHLOROTHIAZIDE PLUS IRBESARTAN; HYDROCHLOROTHIAZIDE PLUS LISINOPRIL; HYDROCHLOROTHIAZIDE PLUS LOSARTAN; HYDROCHLOROTHIAZIDE PLUS QUINAPRIL; HYDROCHLOROTHIAZIDE PLUS RAMIPRIL; HYDROCHLOROTHIAZIDE PLUS VALSARTAN; KARVEZID; LISINOPRIL; LOSARTAN POTASSIUM; METOPROLOL; PERINDOPRIL; QUINAPRIL; RAMIPRIL; RILACE; RILMENIDINE; SINORETIC; SINORETIK; TELMISARTAN; TRANDOLAPRIL; TRANDOLAPRIL PLUS VERAPAMIL; VALSARTAN; VASOLAPRIL;

ACE GENE; ADULT; AGED; ANGIONEUROTIC EDEMA; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; DISEASE COURSE; DNA POLYMORPHISM; DRUG SUBSTITUTION; DRUG WITHDRAWAL; ESSENTIAL HYPERTENSION; FEMALE; GENE; GENOTYPE; HUMAN; LABORATORY TEST; MAJOR CLINICAL STUDY; MALE; PHARMACOGENOMICS;

EID: 48249094276     PISSN: 03010546     EISSN: 15781267     Source Type: Journal    
DOI: 10.1157/13124715     Document Type: Article

References (39)

1. Cicardi M, Zingale LC, Bergamaschini L, Agostini A. Angioedema associated with angiotensin-converting enzyme inhibitor use. Outcome after switching to a different treatment. Arch Intern Med. 2004; 164: 910-913.
2. Kaplan AP, Greaves MW. Angioedema. J Am Acad Dermatol 2005; 373-388.
3. Campell DJ. Vasopeptidase inhibition a double-edged sword? Hypertension. 2003 41: 383-389.
4. ACE inhibitörleri. Çev. Editörü: Üresin Y. 2004 Avrupa Tip Yayinevi sayfa: 1-9.
5. Stergiou GS, Skeva II. Renin-Angiotensin System blockade at the level of the Angiotensin Converting Enzyme or the Angiotensin Type-1 Receptor: Similarities and differences. Current Topics in Medicinal Chemistry 2004; 4: 473-481.
6. Angiotensin I-Converting Enzyme. OMIM (Online Mendelian Inheritance in Man). Johns Hopkins University. Victor A. Mckusick (last updated) 2006.
7. Karim MY. Fresh-frozen plasma as a treatment for life-threatening ACE-inhibitor angioedema. J Allergy Clin Immunol. 2002; 109: 2, 370-371.
8. Vleeming W, van Amsterdam JG, Stricker BH, Wildt DJ. ACE inhibitor-induced angioedema. Incidence, prevention and management. Drug Saf. 1998 Mar; 18(3): 171-188.
9. Chan TF, Kalira D. Angiotensin - converting enzyme inhibitors as a cause of unilateral tongue angioedema in a 68-year-old woman. Am J Emerg Med. 2006 Mar; 24(2): 249-50.
10. Bas M, Hofmann TK, Bier H, Kojda G. Increased C-reactive protein in ACE-inhibitor-induced angioedema. Br J Clin Pharmacol. 2005 59(2): 233-238.
11. Bhalla M, Thami GP. Delayed diagnosis of angiotensin - converting enzyme (ACE) inhibitor induced angioedema and urticaria. Clin Exper Derm. 2003; 28: 321-334.
12. Morimoto T, Gandhi TK, Fiskio JM, Seger AC, So JW, Cook EF, et al. An evaluation of risk factors for adverse drug events associated with angiotensin-converting enzyme inhibitors. J Eval In Clin Prac. 2004; 10, 4: 499-509.
13. Lefebvre J, Murphey LJ, Hartert TV, Shan RJ, Simmons WH, Brown NJ. Dipeptidyl peptisade IV activity in patients with ACE inhibitor associated angioedema. Hypertension 2002; 39(part 2): 460-464.
14. Cugno M, Nussberger J, Cicardi M, Agostoni A. Bradykinin and the pathophysiology of angioedema. International Immunopharmacology 2003 3: 311-317.
15. Kim KS, Kumar S, Simmons WH, Brown NJ. Inhibition of aminopeptidase P potentiates wheal response to bradykinin in angiotensin-converting enzyme inhibitor-treated humans. J Pharmacol Exp Therap. 2000; 292: 295-298.
16. Nussberger J, Cugno M, Amstutz C, Cicardi M, Pellacani A, Agostoni A. Plasma bradykinin in angioedema. The Lancet 1998; 351: 1693-1697.
17. Duan QL, Nikpoor B, Dube MP, et al. A variant in XPNPEP2 is associated with angioedema induced by angiotensin I-converting enzyme inhibitors. Am J Hum Genet. 2005; 77: 617-626.
18. Molinaro G, Cugno M, Perez M, Lepage Y, Gervais N, Agostoni A. Angiotensin-Converting enzyme inhibitor-associated angioedema is characterized by a slower degradation of des-arginine-bradykinin. J Pharma and Exper Therapeutics. 2002; 303 (1): 232-237.
19. Moreau ME, Garbacki N, Molinaro G, Brown NJ, Marceau F, Adam A. The kallikrein-kinin system: Current and future pharmacological targets. J Pharmacol Sci. 2005; 99: 6-38.
20. Urhan M, Deǧirmenci I, Harmanci E, Gunes HV, Metintas M, Basaran A. High frequency of DD polymorphism of the Angiotensin-Converting Enzyme gene in Turkish asthmatic patients. Allergy and Asthma Proc. 2004; 25: 243-247.
21. Öztürk MA, Çalgüneri M, Kiraz S, Ertenli I, Onat AM, Üreten K, et al. Angiotensin-converting enzyme gene polymorphism in Behçet's disease. Clin Rheumatol. 2004; 23: 142-146.
22. Bor Kucukatay M, Turgut S, Emmungil G, Turgut G, Kucukatay V. Increased deformability of red blood cell is associated with a deletion polymorphism of the Angiotensin-Converting enzyme gene. Tohoku J Exp Med. 2006; 208: 147-155.
23. Sayed-Tabatabaei FA, Oostra BA, Isaacs A, van Duijn C.M, Witteman JCM. ACE Polymorphisms. Circ Res. 2006; 98: 1123-1133.
24. Scharplatz M, Puhan MA, Steurer J, Bachmann LM. Study Protocol. What is the impact of the ACE gene insertion/deletion (I/D) polymorphism on the clinical effectiveness and adverse events of ACE inhibitors? - Protocol of a systematic review. BMC Medical Genetics 2004; 5:23, 1-6.
25. Mc Namarra D.M, Holubkov R, Janosko K, Palmer A, Wang JJ, MacGowan GA, et al. Pharmacogenetics interaction between β-blocker therapy and the angiotensin -converting enzyme deletion polymorphism in patients with congestive heart failure. Circulation 2001; 103: 1644-1648.
26. Matsubara M, Suzuki M, Fujiwara T, Kikuya M, Metoki H, Michimata M, et al. Angiotensin-converting enzyme I/D polymorphism and hypertension: The Ohasama study. J Hypertens. 2002 20: 1121-1126.
27. Kritchevsky SB, Nicklas BJ, Visser M, Simonsick EM, Newman AB, Harris TB, et al. Angiotensin-converting enzyme insertion/ deletion genotype, exercise, and physical decline. JAMA. 2005 Aug 10;294 (6):691-8.
28. Tanriverdi H, Kaftan HA, Evrengul H, Dursunoglu D, Turgut G, Kilic M. QT dispersion and left ventricular hypertrophy in athletes: relationship with angiotensin-converting enzyme I/D polymorphism. Acta Cardiol. 2005 Aug;60(4):387-93.
29. Ergen HA, Hatemi H, Agachan B, Camlica H, Isbir T. Angiotensin-I converting enzyme gene polymorphism in Turkish type 2 diabetic patients. Experimental and Molecular Medicine 2004; 36(4): 345-350.
30. Benassiano J, Crestani B, Mestari F, Klouche W, Neukirch F, Hacein-Bey S, et al. High frequency of a deletion polymorphism of the ACE gene in asthma. J Allergy Clin Immunol. 1997; 53-57.
31. Pillans PI, Coulter DM, Black P. Angioedema and urticaria with angiotensin converting enzyme inhibitors. Eur J Clin Pharmacol. 1996 51: 123-126.
32. Gibbs CR, Lip GY, Beevers DG. Angioedema due to ACE inhibitors: increased risk in patients of African origin. Br J Clin Pharmacol. 1999 Dec;48(6):861-5.
33. Zirkle M, Bhattacharyya N. Predictors of airway intervention in angioedema of the head and neck. Otolaryngol Head and Neck Surg. 2000; 123: 240-245.
34. Borazan A, Üstün H, Yilmaz A. Angioedema induced by angiotensin II blocker telmisartan. Allergy 2003; 58:454.
35. Chiu AG, Krowiak EJ, Deeb ZE. Angioedema associated with angiotensin II receptor antagonists; Challenging our knowledge of angioedema and its etiology. Laryngoscope 2001; 111: 1729-1731.
36. Martinez Alonso JC, Dominguez Ortega FJ, Méndez Alcalde J, Fuentes Gonzalo MJ. Angioedema due to valsartan. Allergy 2003:58: 367-369.
37. Howes LG, Tran D. Can angiotensin receptor antagonists be used safely in patients with previous ACE inhibitor-induced angioedema? Drug Saf 2002; 25(2):73-6.
38. Baykal Y, Gök F. Anjiotensin II Reseptör Blokerleri ve Tedavide Kullanimi. Sendrom 2002 Şubat: 91-99.
39. Ducroix JP, Outurquin S, Benabes-Jezraoui B, Gras V, Chaby G, Strunski V, et al. Angioedema and angiotensin converting enzyme inhibitors: A report of 19 cases. La revue de médecine interne. 2004; 25: 501-506.