Elevation of XPA protein level in testis tumor cells without increasing resistance to cisplatin or UV radiation

Molecular Carcinogenesis

Volumn 47, Issue 8, 2008, Pages 580-586

  Köberle, Beate ^a,c   Roginskaya, Vera ^a   Zima, Karen S ^a   Masters, John R W ^b   Wood, Richard D ^a  

^a UNIVERSITY OF PITTSBURGH CANCER INSTITUTE   (United States)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c JOHANNES GUTENBERG UNIVERSITY   (Germany)

Author keywords

Cisplatin; DNA repair; Pyrimidine dimer; Testis tumor cells; Ultraviolet light

Indexed keywords

CISPLATIN; XERODERMA PIGMENTOSUM GROUP A PROTEIN;

ARTICLE; CANCER CHEMOTHERAPY; CANCER RADIOTHERAPY; CANCER RESISTANCE; CELL LINE; DNA REPAIR; HUMAN; HUMAN CELL; NUCLEOLUS; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RADIATION EXPOSURE; RADIOSENSITIVITY; TESTIS TUMOR; TUMOR CELL; ULTRAVIOLET RADIATION;

CELL LINE, TUMOR; CISPLATIN; DIMERIZATION; DNA; DNA REPAIR; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MALE; PYRIMIDINES; TESTICULAR NEOPLASMS; TESTIS; TUMOR SUPPRESSOR PROTEIN P53; ULTRAVIOLET RAYS; XERODERMA PIGMENTOSUM GROUP A PROTEIN;

EID: 48149109845     PISSN: 08991987     EISSN: 10982744     Source Type: Journal    
DOI: 10.1002/mc.20418     Document Type: Article

References (31)

1. Masters JRW, Osborne EJ, Walker MC, Parris CN. Hypersensitivity of human testis-tumour cell lines to chemotherapeutic drugs. Int J Cancer 1993;53:340-346.
2. Bosl GJ, Motzer RJ. Testicular germ-cell cancer. N Engl J Med 1997;337:242-253.
3. Bedford P, Fichtinger-Schepman AMJ, Shellard SA, Walker MC, Masters JRW, Hill BT. Differential repair of platinum-DNA adducts in human bladder and testicular tumor continuous cell lines. Cancer Res 1988;48:3019-3024.
4. Hill BT, Scanlon KJ, Hansson J, et al. Deficient repair of cisplatin-DNA adducts identified in human testicular teratoma cell-lines established from tumors from untreated patients. Eur J Cancer 1994;30A:832-837.
5. Köberle B, Grimaldi KA, Sunters A, Hartley JA, Kelland LR, Masters JR. DNA repair capacity and cisplatin sensitivity of human testis tumour cells. Int J Cancer 1997;70:551-555.
6. Kartalou M, Essigmann JM. Mechanisms of resistance to cisplatin. Mutat Res 2001;478:23-43.
7. Liu N, Lamerdin JE, Tebbs RS, et al. XRCC2 and XRCC3, new human RAD51-family members, promote chromosome stability and protect against DMA cross-links and other damages. Mol Cell 1998;1:783-793.
8. Albertella MR, Green CM, Lehmann AR, O'Connor MJ. A role for polymerase eta in the cellular tolerance to cisplatin-induced damage. Cancer Res 2005;65:9799-9806.
9. Nojima K, Hochegger H, Saberi A, et al. Multiple repair pathways mediate tolerance to chemotherapeutic cross-linking agents in vertebrate cells. Cancer Res 2005;65:11704-11711.
10. Friedberg EC, Walker GC, Siede W, Wood RD, Schultz RA, Ellenberger T. DNA repair and mutagenesis, 2nd edition. Washington, DC: ASM Press; 2006. 1118 p.
11. Köberle B, Masters JR, Hartley JA, Wood RD. Defective repair of cisplatin-induced DNA damage caused by reduced XPA protein in testicular germ cell tumours. Curr Biol 1999;9:273-276.
12. Welsh C, Day R, McGurk C, Masters JR, Wood RD, Koberle B. Reduced levels of XPA, ERCC1 and XPF DNA repair proteins in testis tumor cell lines. Int J Cancer 2004;110:352-361.
13. Brown JM, Wilson G. Apoptosis genes and resistance to cancer therapy: What does the experimental and clinical data tell us? Cancer Biol Ther 2003;2:477-490.
14. Masters JR, Köberle B. Curing metastatic cancer: Lessons from testicular germ-cell tumours. Nat Rev Cancer 2003;3:517-525.
15. Mayer F, Honecker F, Looijenga LH, Bokemeyer C. Towards an understanding of the biological basis of response to cisplatin-based chemotherapy in germ-cell tumors. Ann Oncol 2003;14:825-832.
16. Köberle B, Roginskaya V, Wood RD. XPA protein as a limiting factor for nucleotide excision repair and UV sensitivity in human cells. DNA Repair 2006;5:641-648.
17. Branson DL, Andrews PW, Solter D, Cervenka J, Lange PH, Fraley EE. Cell line derived from a metastasis of a human testicular germ cell tumor. Cancer Res 1980;40:2500-2506.
18. Mori T, Nakane M, Hattori T, Matsunaga T, Ihara M, Nikaido O. Simultaneous establishment of monoclonal-antibodies specific for either cyclobutane pyrimidine dimer or (6-4)photoproduct from the same mouse immunized with ultraviolet-irradiated DNA. Photochem Photobiol 1991;54:225-232.
19. Clement V, Dunand-Sauthier I, Clarkson SG. Suppression of UV-induced apoptosis by the human DNA repair protein XPG. Cell Death Differ 2006;13:478-488.
20. McCready S. A dot-blot immunoassay for measuring repair of ultraviolet photoproducts. Methods Mol Biol 2006;314:229-238.
21. Jones CJ, Wood RD. Preferential binding of the xeroderma pigmentosum group A complementing protein to damaged DNA. Biochemistry 1993;32:12096-12104.
22. Geley S, Kramer E, Gieffers C, Gannon J, Peters J-M, Hunt T. Anaphase-promoting complex/cyclosome-dependent proteolysis of human cyclin A starts at the beginning of mitosis and is not subject to the spindle assembly checkpoint. J Cell Biol 2001;153:137-148.
23. Chresta CM, Masters JR, Hickman JA. Hypersensitivity of human testicular tumors to etoposide-induced apoptosis is associated with functional p53 and a high Bax:Bcl-2 ratio. Cancer Res 1996;56:1834-1841.
24. Masters JR, Thomas R, Hall AG, et al. Sensitivity of testis tumour cells to chemotherapeutic drugs: Role of detoxifying pathways. Eur J Cancer 1996;32A:1248-1253.
25. Miura N, Miyamoto I, Asahina H, Satokata , Tanaka K, Okada Y. Identification and characterization of XPAC protein, the gene product of the human XPAC (xeroderma pigmentosum group A complementing) gene. J Biol Chem 1991;266:19786-19789.
26. Rademakers S, Volker M, Hoogstraten D et al. Xeroderma pigmentosum group A protein loads as a separate factor onto DNA lesions. Mol Cell Biol 2003;23:5755-5767.
27. Wu X, Shell SM, Liu Y, Zou Y. ATR-dependent checkpoint modulates XPA nuclear import in response to UV irradiation. Oncogene 2007;26:757-764.
28. Parris CN, Arlett CF, Lehmann AR, Green MH, Masters JR. Differential sensitivities to gamma raciation of human bladder and testicular tumour cell lines. Int J Radiat Biol 1988;53:599-608.
29. Arriola EL, Rodriguez-Lopez AM, Hickman JA, Chresta CM. Bcl-2 overexpression results in reciprocal downregulation of Bcl-X(L) and sensitizes human testicular germ cell tumours to chemotherapy-induced apoptosis. Oncogene 1999;18:1457-1464.
30. Taniguchi T, Tischkowitz M, Ameziane N, et al. Disruption of the Fanconi anemia-BRCA pathway in cisplatin-sensitive ovarian tumors. Nat Med 2003;9:568-574.
31. Kenny MK, Schlegel U, Furneaux H, Hurwitz J. The role of human single-stranded DNA binding protein and its individual subunits in simian virus 40 DNA replication. J Biol Chem 1990;265:7693-7700.