Non-classical 21-hydroxylase deficiency in boys with prepubertal or pubertal gynecomastia

European Journal of Pediatrics

Volumn 167, Issue 9, 2008, Pages 1083-1084

  Wasniewska, Malgorzata ^a   Raiola, Giuseppe ^b   Galati, Maria Concetta ^b   Salzano, Giuseppina ^a   Rulli, Immacolata ^a   Zirilli, Giuseppina ^a   De Luca, Filippo ^a,c  

^a UNIVERSITY OF MESSINA   (Italy)

^b PUGLIESE CIACCIO HOSPITAL   (Italy)

^c UNIVERSITY OF MESSINA   (Italy)

Author keywords

21 hydroxylase deficiency; Non classical congenital adrenal hyperplasia; Prepubertal gynecomastia; Pubertal gynecomastia

Indexed keywords

CORTICOTROPIN; GLUCOCORTICOID; STEROID 21 MONOOXYGENASE;

ARTICLE; CASE REPORT; CLINICAL FEATURE; GENETIC ANALYSIS; GYNECOMASTIA; HORMONE DETERMINATION; HUMAN; MALE; PREPUBERTY; PRIORITY JOURNAL; SCHOOL CHILD; STEROID 21 MONOOXYGENASE DEFICIENCY;

ADOLESCENT; ADRENAL HYPERPLASIA, CONGENITAL; CHILD; GYNECOMASTIA; HUMANS; HYDROCORTISONE; MALE;

EID: 48149097395     PISSN: 03406199     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00431-007-0625-6     Document Type: Article

References (6)

1. IA Auchterlonie J Cameron AM Wallace BT Rudd M Hudson PJ Smail 1985 Pre-pubertal gynaecomastia as the presenting feature of late-onset 21-hydroxylase deficiency Horm Res 22 94 99
2. PR Blackett DA Freeman 1996 Androstenedione aromatization as a cause of gynecomastia in 11beta-hydroxylase and 21-hydroxylase deficiencies Endocr Pract 2 90 93
3. R Einav-Bachar M Phillip Y Aurbach-Klipper L Lazar 2004 Prepubertal gynaecomastia: aetiology, course and outcome Clin Endocrinol (Oxf) 61 55 60
4. Gikas P, Mokbel K (2007) Management of gynaecomastia: an update. Int J Clin Pract 2007 Mar 16 [Epub ahead of print]
5. Z Hochberg L Even Z Zadik 1991 Mineralocorticoids in the mechanism of gynecomastia in adrenal hyperplasia caused by 11 beta-hydroxylase deficiency J Pediatr 118 258 260
6. M Wasniewska G Di Pasquale I Rulli G Salzano M Caruso S Indovina L Di Pasquale G Zirilli F De Luca 2007 In Sicilian ethnic group non-classical congenital adrenal hyperplasia is frequently associated with a very mild genotype J Endocrinol Invest 30 181 185