메뉴 건너뛰기




Volumn 47, Issue 8, 2008, Pages 629-637

Fucoidan from Laminaria cichorioides inhibits AP-1 transactivation and cell transformation in the mouse epidermal JB6 cells

Author keywords

AP 1; c fos; c jun; Cell transformation; EGFR; Fucoidan

Indexed keywords

CELL SURFACE RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; FUCOIDIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHORBOL 13 ACETATE 12 MYRISTATE; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR AP 1;

EID: 48149084449     PISSN: 08991987     EISSN: 10982744     Source Type: Journal    
DOI: 10.1002/mc.20428     Document Type: Article
Times cited : (40)

References (52)
  • 1
    • 0001004230 scopus 로고
    • Algal polysaccharides
    • New York: Academic Press;
    • Painter T. Algal polysaccharides. The polysaccharides, Vol. 2. New York: Academic Press; 1983. pp. 195-285.
    • (1983) The polysaccharides , vol.2 , pp. 195-285
    • Painter, T.1
  • 3
    • 0035913184 scopus 로고    scopus 로고
    • Structural studies on fucoidans from the brown seaweed Sargassum stenophyllum
    • Duarte ME, Cardoso MA, Noseda MD, Cerezo AS. Structural studies on fucoidans from the brown seaweed Sargassum stenophyllum. Carbohydr Res 2001;333:281-293.
    • (2001) Carbohydr Res , vol.333 , pp. 281-293
    • Duarte, M.E.1    Cardoso, M.A.2    Noseda, M.D.3    Cerezo, A.S.4
  • 4
    • 0342547019 scopus 로고    scopus 로고
    • Anticoagulant fucoidan fractions from Fucus vesiculosus induce platelet activation in vitro
    • Durig J, Bruhn T, Zurborn KH, Gutensohn K, Bruhn HD, Beress L. Anticoagulant fucoidan fractions from Fucus vesiculosus induce platelet activation in vitro. Thromb Res 1997;85:479-491.
    • (1997) Thromb Res , vol.85 , pp. 479-491
    • Durig, J.1    Bruhn, T.2    Zurborn, K.H.3    Gutensohn, K.4    Bruhn, H.D.5    Beress, L.6
  • 5
    • 0027494436 scopus 로고
    • A revised structure for fucoidan may explain some of its biological activities
    • Patankar MS, Oehninger S, Barnett T, Williams RL, Clark GF. A revised structure for fucoidan may explain some of its biological activities. J Biol Chem 1993;268:21770-21776.
    • (1993) J Biol Chem , vol.268 , pp. 21770-21776
    • Patankar, M.S.1    Oehninger, S.2    Barnett, T.3    Williams, R.L.4    Clark, G.F.5
  • 6
    • 0035961371 scopus 로고    scopus 로고
    • A disaccharide repeat unit is the major structure in fucoidans from two species of brown algae
    • Chevolot L, Mulloy B, Ratiskol J, Foucault A, Colliec-Jouault S. A disaccharide repeat unit is the major structure in fucoidans from two species of brown algae. Carbohydr Res 2001;330:529-535.
    • (2001) Carbohydr Res , vol.330 , pp. 529-535
    • Chevolot, L.1    Mulloy, B.2    Ratiskol, J.3    Foucault, A.4    Colliec-Jouault, S.5
  • 7
    • 0034595587 scopus 로고    scopus 로고
    • Oversulfated fucoidan inhibits the basic fibroblast growth factor-induced tube formation by human umbilical vein endothelial cells: Its possible mechanism of action
    • Soeda S, Kozako T, Iwata K, Shimeno H. Oversulfated fucoidan inhibits the basic fibroblast growth factor-induced tube formation by human umbilical vein endothelial cells: Its possible mechanism of action. Biochim Biophys Acta 2000;1497:127-134.
    • (2000) Biochim Biophys Acta , vol.1497 , pp. 127-134
    • Soeda, S.1    Kozako, T.2    Iwata, K.3    Shimeno, H.4
  • 8
    • 8944256874 scopus 로고    scopus 로고
    • Antitumor and antiproliferative effects of a fucan extracted from ascophyllum nodosum against a non-small-cell bronchopulmonary carcinoma line
    • Riou D, Colliec-Jouault S, Pinczon du Sel D, et al. Antitumor and antiproliferative effects of a fucan extracted from ascophyllum nodosum against a non-small-cell bronchopulmonary carcinoma line. Anticancer Res 1996;16:1213-1218.
    • (1996) Anticancer Res , vol.16 , pp. 1213-1218
    • Riou, D.1    Colliec-Jouault, S.2    Pinczon du Sel, D.3
  • 9
    • 0027751896 scopus 로고
    • Antitumor activity and immunological properties of marine algal polysaccharides, especially fucoidan, prepared from Sargassum thunbergii of Phaeophyceae
    • Itoh H, Noda H, Amano H, Zhuaug C, Mizuno T, Ito H. Antitumor activity and immunological properties of marine algal polysaccharides, especially fucoidan, prepared from Sargassum thunbergii of Phaeophyceae. Anticancer Res 1993;13:2045-2052.
    • (1993) Anticancer Res , vol.13 , pp. 2045-2052
    • Itoh, H.1    Noda, H.2    Amano, H.3    Zhuaug, C.4    Mizuno, T.5    Ito, H.6
  • 10
    • 0029278080 scopus 로고
    • Antitumor active fucoidan from the brown seaweed, umitoranoo (Sargassum thunbergii)
    • Zhuang C, Itoh H, Mizuno T, Ito H. Antitumor active fucoidan from the brown seaweed, umitoranoo (Sargassum thunbergii). Biosci Biotechnol Biochem 1995;59:563-567.
    • (1995) Biosci Biotechnol Biochem , vol.59 , pp. 563-567
    • Zhuang, C.1    Itoh, H.2    Mizuno, T.3    Ito, H.4
  • 11
    • 0037437728 scopus 로고    scopus 로고
    • Oversulfation of fucoidan enhances its anti-angiogenic and antitumor activities
    • Koyanagi S, Tanigawa N, Nakagawa H, Soeda S, Shimeno H. Oversulfation of fucoidan enhances its anti-angiogenic and antitumor activities. Biochem Pharmacol 2003;65:173-179.
    • (2003) Biochem Pharmacol , vol.65 , pp. 173-179
    • Koyanagi, S.1    Tanigawa, N.2    Nakagawa, H.3    Soeda, S.4    Shimeno, H.5
  • 12
    • 0034307516 scopus 로고    scopus 로고
    • Sulfated glycans induce rapid hematopoietic progenitor cell mobilization: Evidence for selectin-dependent and independent mechanisms
    • Frenette PS, Weiss L. Sulfated glycans induce rapid hematopoietic progenitor cell mobilization: Evidence for selectin-dependent and independent mechanisms. Blood 2000;96:2460-2468.
    • (2000) Blood , vol.96 , pp. 2460-2468
    • Frenette, P.S.1    Weiss, L.2
  • 13
    • 0036092976 scopus 로고    scopus 로고
    • Sulfated polysaccharides increase plasma levels of SDF-1 in monkeys and mice: Involvement in mobilization of stem/progenitor cells
    • Sweeney EA, Lortat-Jacob H, Priestley GV, Nakamoto B, Papayannopoulou T. Sulfated polysaccharides increase plasma levels of SDF-1 in monkeys and mice: Involvement in mobilization of stem/progenitor cells. Blood 2002;99:44-51.
    • (2002) Blood , vol.99 , pp. 44-51
    • Sweeney, E.A.1    Lortat-Jacob, H.2    Priestley, G.V.3    Nakamoto, B.4    Papayannopoulou, T.5
  • 14
    • 0037243452 scopus 로고    scopus 로고
    • Preventive effects of Cladosiphon fucoidan against Helicobacter pylori infection in Mongolian gerbils
    • Shibata H, Iimuro M, Uchiya N, et al. Preventive effects of Cladosiphon fucoidan against Helicobacter pylori infection in Mongolian gerbils. Helicobacter 2003;8:59-65.
    • (2003) Helicobacter , vol.8 , pp. 59-65
    • Shibata, H.1    Iimuro, M.2    Uchiya, N.3
  • 15
    • 0028079661 scopus 로고
    • Blocking of tumor promoter-induced AP-1 activity inhibits induced transformation in JB6 mouse epidermal cells
    • Dong Z, Birrer MJ, Watts RG, Matrisian LM, Colburn NH. Blocking of tumor promoter-induced AP-1 activity inhibits induced transformation in JB6 mouse epidermal cells. Proc Natl Acad Sci USA 1994;91:609-613.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 609-613
    • Dong, Z.1    Birrer, M.J.2    Watts, R.G.3    Matrisian, L.M.4    Colburn, N.H.5
  • 16
    • 0025720735 scopus 로고
    • The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation
    • Angel P, Karin M. The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation. Biochim Biophys Acta 1991;1072:129-157.
    • (1991) Biochim Biophys Acta , vol.1072 , pp. 129-157
    • Angel, P.1    Karin, M.2
  • 17
    • 0026636883 scopus 로고
    • The regulation of transcription by phosphorylation
    • Hunter T, Karin M. The regulation of transcription by phosphorylation. Cell 1992;70:375-387
    • (1992) Cell , vol.70 , pp. 375-387
    • Hunter, T.1    Karin, M.2
  • 18
    • 0023238874 scopus 로고
    • Requirement for intrinsic protein tyrosine kinase in the immediate and late actions of the EGF receptor
    • Chen WS, Lazar CS, Poenie M, Tsien RY, Gill GN, Rosenfeld MG. Requirement for intrinsic protein tyrosine kinase in the immediate and late actions of the EGF receptor. Nature 1987;328:820-823.
    • (1987) Nature , vol.328 , pp. 820-823
    • Chen, W.S.1    Lazar, C.S.2    Poenie, M.3    Tsien, R.Y.4    Gill, G.N.5    Rosenfeld, M.G.6
  • 20
    • 0025313141 scopus 로고
    • Anti-synthetic peptide antibody reacting at the fusion junction of deletion-mutant epidermal growth factor receptors in human glioblastoma
    • Humphrey PA, Wong AJ, Vogelstein B, et al. Anti-synthetic peptide antibody reacting at the fusion junction of deletion-mutant epidermal growth factor receptors in human glioblastoma. Proc Natl Acad Sci USA 1990;87:4207-4211.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 4207-4211
    • Humphrey, P.A.1    Wong, A.J.2    Vogelstein, B.3
  • 21
    • 0026801871 scopus 로고
    • Expression of EGF, TGF-alpha and EGFR in squamous cell lung carcinomas
    • Gorgoulis V, Aninos D, Mikou P, et al. Expression of EGF, TGF-alpha and EGFR in squamous cell lung carcinomas. Anticancer Res 1992;12:1183-1137.
    • (1992) Anticancer Res , vol.12 , pp. 1183-1137
    • Gorgoulis, V.1    Aninos, D.2    Mikou, P.3
  • 22
    • 0027083325 scopus 로고
    • Anti-sense transforming growth factor alpha oligonucleotides inhibit autocrine stimulated proliferation of a colon carcinoma cell line
    • Sizeland AM, Burgess AW. Anti-sense transforming growth factor alpha oligonucleotides inhibit autocrine stimulated proliferation of a colon carcinoma cell line. Mol Biol Cell 1992;3:1235-1243.
    • (1992) Mol Biol Cell , vol.3 , pp. 1235-1243
    • Sizeland, A.M.1    Burgess, A.W.2
  • 23
    • 0031936410 scopus 로고    scopus 로고
    • Specificity within the EGF family/ErbB receptor family signaling network
    • Riese DJ, II., Stern DF. Specificity within the EGF family/ErbB receptor family signaling network. Bioessays 1998;20:41-48.
    • (1998) Bioessays , vol.20 , pp. 41-48
    • Riese II, D.J.1    Stern, D.F.2
  • 24
    • 14844334157 scopus 로고    scopus 로고
    • Phorbol 12-myristate 13-acetate induces eoidermal growth factor receptor transactivation via protein kinase Cdelta/c-Src pathways in glioblastoma cells
    • Amos S, Martin PM, Polar GA, Parsons SJ, Hussaini IM. Phorbol 12-myristate 13-acetate induces eoidermal growth factor receptor transactivation via protein kinase Cdelta/c-Src pathways in glioblastoma cells. J Biol Chem 2005;280:7729-7738.
    • (2005) J Biol Chem , vol.280 , pp. 7729-7738
    • Amos, S.1    Martin, P.M.2    Polar, G.A.3    Parsons, S.J.4    Hussaini, I.M.5
  • 25
    • 0032708318 scopus 로고    scopus 로고
    • A new procedure for the separation of water-soluble polysaccharides from brown seaweeds
    • Zvyagintseva TN, Shevchenko NM, Popivnich IB, et al. A new procedure for the separation of water-soluble polysaccharides from brown seaweeds. Carbohydr Res 1999;322:32-39.
    • (1999) Carbohydr Res , vol.322 , pp. 32-39
    • Zvyagintseva, T.N.1    Shevchenko, N.M.2    Popivnich, I.B.3
  • 26
    • 33749946901 scopus 로고
    • Colorimetric method for determination of sugars and related substances
    • Dubois M, Gilles K, Hamilton J, Robets P, Smith F. Colorimetric method for determination of sugars and related substances. Anal Chem 1956;28:350-356
    • (1956) Anal Chem , vol.28 , pp. 350-356
    • Dubois, M.1    Gilles, K.2    Hamilton, J.3    Robets, P.4    Smith, F.5
  • 27
    • 0000674033 scopus 로고
    • A photometric adaptation of the Somogy method for determination of glucose
    • Nelson TE. A photometric adaptation of the Somogy method for determination of glucose. J Biol Chen 1944;153:375-381.
    • (1944) J Biol Chen , vol.153 , pp. 375-381
    • Nelson, T.E.1
  • 28
    • 0019788391 scopus 로고
    • Dissociation of mitogenesis and late-stage promotion of tumor cell phenotype by phorbol esters: Mitogen-resistant variants are sensitive to promotion
    • Colburn NH, Wendel EJ, Abruzzo G. Dissociation of mitogenesis and late-stage promotion of tumor cell phenotype by phorbol esters: Mitogen-resistant variants are sensitive to promotion. Proc Natl Acad Sci USA 1981;73:6912-6916.
    • (1981) Proc Natl Acad Sci USA , vol.73 , pp. 6912-6916
    • Colburn, N.H.1    Wendel, E.J.2    Abruzzo, G.3
  • 29
    • 20344402567 scopus 로고    scopus 로고
    • Water-soluble polysaccharides of some brown algae of the Russian Far-East. Structure and biological action of low-molecular mass polyuronans
    • Zvyagintseva TN, Shevchenko NM, Nazarenko EL, et al. Water-soluble polysaccharides of some brown algae of the Russian Far-East. Structure and biological action of low-molecular mass polyuronans. J Exp Mar Bio Ecol 2005;320:123-131.
    • (2005) J Exp Mar Bio Ecol , vol.320 , pp. 123-131
    • Zvyagintseva, T.N.1    Shevchenko, N.M.2    Nazarenko, E.L.3
  • 30
    • 0042734561 scopus 로고    scopus 로고
    • Water-soluble polysaccharides of some far-eastern brown seaweeds. Distribution, structure, and their dependence on the developmental conditions
    • Zvyagintseva TN, Shevchenko NM, Nazarenko EL, et al. Water-soluble polysaccharides of some far-eastern brown seaweeds. Distribution, structure, and their dependence on the developmental conditions. J Exp Mar Biol Ecol 2003;294:1-13.
    • (2003) J Exp Mar Biol Ecol , vol.294 , pp. 1-13
    • Zvyagintseva, T.N.1    Shevchenko, N.M.2    Nazarenko, E.L.3
  • 31
    • 17844394391 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase activation in UV-induced signal transduction
    • Bode AM, Dong Z. Mitogen-activated protein kinase activation in UV-induced signal transduction. Sci STKE 2003;2003:RE2.
    • (2003) Sci STKE 2003
    • Bode, A.M.1    Dong, Z.2
  • 32
    • 0031950853 scopus 로고    scopus 로고
    • Epidermal growth factor induction of the c-jun promoter by a Rac pathway
    • Clarke N, Arenzana N, Hai T, Minden A, Prywes R. Epidermal growth factor induction of the c-jun promoter by a Rac pathway. Mol Cell Biol 1998;18:1065-1073.
    • (1998) Mol Cell Biol , vol.18 , pp. 1065-1073
    • Clarke, N.1    Arenzana, N.2    Hai, T.3    Minden, A.4    Prywes, R.5
  • 33
    • 0037184904 scopus 로고    scopus 로고
    • ATF1 phosphorylation Dy the ERK MAPK pathway is required for epidermal growth factor-induced c-jun expression
    • Gupta P, Prywes R. ATF1 phosphorylation Dy the ERK MAPK pathway is required for epidermal growth factor-induced c-jun expression. J Biol Chem 2002;277:50550-50556.
    • (2002) J Biol Chem , vol.277 , pp. 50550-50556
    • Gupta, P.1    Prywes, R.2
  • 34
    • 0025769412 scopus 로고
    • Primary response genes induced by growth factors and tumor promoters
    • Herschman HR. Primary response genes induced by growth factors and tumor promoters. Annu Rev Biochem 1991;60:281-319.
    • (1991) Annu Rev Biochem , vol.60 , pp. 281-319
    • Herschman, H.R.1
  • 35
    • 0023798751 scopus 로고
    • Fos and Jun: The AP-1 connection
    • Curran T, Franza BR Jr. Fos and Jun: The AP-1 connection. Cell 1988;55:395-397.
    • (1988) Cell , vol.55 , pp. 395-397
    • Curran, T.1    Franza Jr, B.R.2
  • 36
    • 0037422199 scopus 로고    scopus 로고
    • Possible role in antiproliferation and apoptosis
    • Tyagi A, Agarwal R, Agarwal C. Grape seed extract inhibits EGF-induced and constitutively active mitogenic signaling but activates JNK in human prostate carcinoma DU14B cells
    • Tyagi A, Agarwal R, Agarwal C. Grape seed extract inhibits EGF-induced and constitutively active mitogenic signaling but activates JNK in human prostate carcinoma DU14B cells: Possible role in antiproliferation and apoptosis. Oncogene 2003;22:1302-1316.
    • (2003) Oncogene , vol.22 , pp. 1302-1316
  • 37
    • 0037198127 scopus 로고    scopus 로고
    • Harvesting cells under anchorage-independent cell transformation conditions for biochemical analyses
    • Dong Z, Cmarik JL. Harvesting cells under anchorage-independent cell transformation conditions for biochemical analyses. Sci STKE 2002;2002:PL7.
    • (2002) Sci STKE 2002
    • Dong, Z.1    Cmarik, J.L.2
  • 38
    • 0038618955 scopus 로고    scopus 로고
    • Sulfated fucans, fresh perspectives: Structures, functions, and biological properties of sulfated fucans and an overview of enzymes active toward this class of polysaccharide
    • Berteau O, Mulloy B. Sulfated fucans, fresh perspectives: Structures, functions, and biological properties of sulfated fucans and an overview of enzymes active toward this class of polysaccharide. Glycobiology 2003;13:29R-40R.
    • (2003) Glycobiology , vol.13
    • Berteau, O.1    Mulloy, B.2
  • 39
    • 0030863948 scopus 로고    scopus 로고
    • Neoplastic transformation of rat thyroid cells requires the junB and fra-1 gene induction which is dependent on the HMGI-C gene product
    • Vallone D, Battista S, Pierantoni GM, et al. Neoplastic transformation of rat thyroid cells requires the junB and fra-1 gene induction which is dependent on the HMGI-C gene product. EMBO J 1997;16:5310-5321.
    • (1997) EMBO J , vol.16 , pp. 5310-5321
    • Vallone, D.1    Battista, S.2    Pierantoni, G.M.3
  • 40
    • 0028300217 scopus 로고
    • Constitutive AP-1 DNA binding and transactivating ability of malignant but not benign mouse epidermal cells
    • Domann FE Jr, Levy JP, Finch JS, Bowden GT. Constitutive AP-1 DNA binding and transactivating ability of malignant but not benign mouse epidermal cells. Mol Carcinog 1994;9:61-66.
    • (1994) Mol Carcinog , vol.9 , pp. 61-66
    • Domann Jr, F.E.1    Levy, J.P.2    Finch, J.S.3    Bowden, G.T.4
  • 41
    • 0032076149 scopus 로고    scopus 로고
    • The pathogenesis of squamous cell cancer: Lessons learned from studies of skin carcinogenesis
    • Yuspa SH. The pathogenesis of squamous cell cancer: Lessons learned from studies of skin carcinogenesis. J Dermatol Sci 1998;17:1-7.
    • (1998) J Dermatol Sci , vol.17 , pp. 1-7
    • Yuspa, S.H.1
  • 42
    • 0032519560 scopus 로고    scopus 로고
    • Inhibitory effects of perillyl alcohol on UVB-induced murine skin cancer and AP-1 transactivation
    • Barthelman M, Chen W, Gensler HL, Huang C, Dong Z, Bowden GT. Inhibitory effects of perillyl alcohol on UVB-induced murine skin cancer and AP-1 transactivation. Cancer Res 1998;58:711-716.
    • (1998) Cancer Res , vol.58 , pp. 711-716
    • Barthelman, M.1    Chen, W.2    Gensler, H.L.3    Huang, C.4    Dong, Z.5    Bowden, G.T.6
  • 43
    • 0030749569 scopus 로고    scopus 로고
    • A dominant negative mutant of jun blocking 12-O-tetradecanoylphorbol-13-acetate-induced invasion in mouse keratinocytes
    • Dong Z, Crawford HC, Lavrovsky V, et al. A dominant negative mutant of jun blocking 12-O-tetradecanoylphorbol-13-acetate-induced invasion in mouse keratinocytes. Mol Carcinog 1997;19:204-212.
    • (1997) Mol Carcinog , vol.19 , pp. 204-212
    • Dong, Z.1    Crawford, H.C.2    Lavrovsky, V.3
  • 44
    • 0029032249 scopus 로고
    • The regulation of AP-1 activity by mitogen-activated protein kinases
    • Karin M. The regulation of AP-1 activity by mitogen-activated protein kinases. J Biol Chem 1995;270:16483-16486.
    • (1995) J Biol Chem , vol.270 , pp. 16483-16486
    • Karin, M.1
  • 45
    • 0030799429 scopus 로고    scopus 로고
    • Inhibition of tumor promoter-induced activator protein 1 activation and cell transformation by tea polyphenols, (-)-epigallocatechin gallate, and theaflavins
    • Dong Z, Ma W, Huang C, Yang CS. Inhibition of tumor promoter-induced activator protein 1 activation and cell transformation by tea polyphenols, (-)-epigallocatechin gallate, and theaflavins. Cancer Res 1997;57:4414-4419.
    • (1997) Cancer Res , vol.57 , pp. 4414-4419
    • Dong, Z.1    Ma, W.2    Huang, C.3    Yang, C.S.4
  • 46
    • 0033569891 scopus 로고    scopus 로고
    • JNK activation is required for JB6 cell transformation induced by tumor necrosis factor-alpha but not by 12-O-tetradecanoylphorbol-13-acetate
    • Huang C, Li J, Ma WY, Dong Z. JNK activation is required for JB6 cell transformation induced by tumor necrosis factor-alpha but not by 12-O-tetradecanoylphorbol-13-acetate. J Biol Chem 1999;274:29672-29676.
    • (1999) J Biol Chem , vol.274 , pp. 29672-29676
    • Huang, C.1    Li, J.2    Ma, W.Y.3    Dong, Z.4
  • 47
    • 0035872409 scopus 로고    scopus 로고
    • Suppression of skin tumorigenesis in c-Jun NH(2)-terminal kinase-2-deficient mice
    • Chen N, Nomura M, She QB, et al. Suppression of skin tumorigenesis in c-Jun NH(2)-terminal kinase-2-deficient mice. Cancer Res 2001;61:3908-3912.
    • (2001) Cancer Res , vol.61 , pp. 3908-3912
    • Chen, N.1    Nomura, M.2    She, Q.B.3
  • 49
    • 0035952656 scopus 로고    scopus 로고
    • Cell communication networks: Epidermal growth factor receptor transactivation as the paradigm for interreceptor signal transmission
    • Gschwind A, Zwick E, Prenzel N, Leserer M, Ullrich A. Cell communication networks: Epidermal growth factor receptor transactivation as the paradigm for interreceptor signal transmission. Oncogene 2001;20:1594-1600.
    • (2001) Oncogene , vol.20 , pp. 1594-1600
    • Gschwind, A.1    Zwick, E.2    Prenzel, N.3    Leserer, M.4    Ullrich, A.5
  • 50
    • 0033757346 scopus 로고    scopus 로고
    • Epidermal growth factor receptor tyrosine kinase inhibitors as anticancer agents
    • discussion 41-22
    • Ciardiello F. Epidermal growth factor receptor tyrosine kinase inhibitors as anticancer agents. Drugs 2000;60:25-32; discussion 41-22.
    • (2000) Drugs , vol.60 , pp. 25-32
    • Ciardiello, F.1
  • 51
    • 0034722889 scopus 로고    scopus 로고
    • The EGF receptor family as targets for cancer therapy
    • Mendelsohn J, Baselga J. The EGF receptor family as targets for cancer therapy. Oncogene 2000;19:6550-6565.
    • (2000) Oncogene , vol.19 , pp. 6550-6565
    • Mendelsohn, J.1    Baselga, J.2
  • 52
    • 0001497590 scopus 로고    scopus 로고
    • Signal transduction events elicited by cancer prevention compounds
    • Kong AN, Yu R, Hebbar V, et al. Signal transduction events elicited by cancer prevention compounds. Mutat Res 2001;480-481:231-241.
    • (2001) Mutat Res
    • Kong, A.N.1    Yu, R.2    Hebbar, V.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.