Reduced size of the amygdala in individuals with 47,XXY and 47,XXX karyotypes

American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics

Volumn 114, Issue 1, 2002, Pages 93-98

  Patwardhan, Anil J ^a   Brown, Wendy E ^a   Bender, Bruce G ^b   Linden, Mary G ^b   Eliez, Stephan ^a   Reiss, Allan L ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NATIONAL JEWISH MEDICAL AND RESEARCH CENTER   (United States)

Author keywords

Amygdala; Hippocampus; Klinefelter syndrome; Magnetic resonance imaging; Sex chromosome aneuploidy

Indexed keywords

ADULT; AMYGDALOID NUCLEUS; ANEUPLOIDY; COHORT ANALYSIS; FEMALE; HIPPOCAMPUS; HUMAN; KARYOTYPING; LONGITUDINAL STUDY; MALE; NEWBORN; NUCLEAR MAGNETIC RESONANCE IMAGING; SEX CHROMOSOME ABERRATION; STATISTICAL ANALYSIS; X CHROMOSOME;

ADULT; AMYGDALA; ANEUPLOIDY; COHORT STUDIES; FEMALE; HIPPOCAMPUS; HUMANS; INFANT, NEWBORN; KARYOTYPING; LONGITUDINAL STUDIES; MAGNETIC RESONANCE IMAGING; MALE; MATCHED-PAIR ANALYSIS; SEX CHROMOSOME ABERRATIONS; X CHROMOSOME;

EID: 48049118700     PISSN: 15524841     EISSN: 1552485X     Source Type: Journal    
DOI: 10.1002/ajmg.10154     Document Type: Article

References (59)

1. Aggleton JP. 1993. The contribution of the amygdala to normal and abnormal emotional states. Trends Neurosci 16:328-333. (Pubitemid 23190650)
2. Amen DG, Stubblefield M, Carmicheal B, Thisted R. 1996. Brain SPECT findings and aggressiveness. Ann Clin Psychiatry 8:129-137.
3. Axelson DA, Doraiswamy PM, McDonald WM, Boyko OB, Tupler LA, Patterson LJ, Nemeroff CB, Ellirwood EH Jr, Krishnan KR. 1993. Hypercortisolemia and hippocampal changes in depression. Psychiatry Res 47:163-173.
4. Bancroft J, Axworthy D, Ratcliffe S. 1982. The personality and psychosexual development of boys with 47 XXY chromosome constitution. J Child Psychol Psychiatry 23:169-180. (Pubitemid 12181071)
5. Bender BG, Puck MH, Salbenblatt JA, Robinson A. 1986. Dyslexia in 47,XXY boys identified at birth. Behav Genet 16:343-354.
6. Bender BG, Linden MG, Robinson A. 1989. Verbal and spatial processing efficiency in 32 children with sex chromosome abnormalities. Pediatr Res 25:577-579. (Pubitemid 19141393)
7. Bender BG, Harmon RJ, Linden MG, Robinson A. 1995. Psychosocial adaptation of 39 adolescents with sex chromosome abnormalities. Pediatrics 96:302-308. (Pubitemid 23292014)
8. Bogerts B, Ashtari M, Degreef G, Alvir JM, Bilder RM, Lieberman JA. 1990. Reduced temporal limbic structure volumes on magnetic resonance images in first episode schizophrenia. Psychiatry Res 35:1-13. (Pubitemid 20203211)
9. Breier A, Buchanan RW, Elkashef A, Munson RC, Kirkpatrick B, Gellad F. 1992. Brain morphology and schizophrenia. A magnetic resonance imaging study of limbic, prefrontal cortex, and caudate structures. Arch Gen Psychiatry 49:921-926.
10. Bryant NL, Buchanan RW, Vladar K, Breier A, Rothman M. 1999. Gender differences in temporal lobe structures of patients with schizophrenia: a volumetric MRI study. Am J Psychiatry 156:603-609. (Pubitemid 29162983)
11. Cooke BM, Tabibnia G, Breedlove SM. 1999. A brain sexual dimorphism controlled by adult circulating androgens. Proc Natl Acad Sci USA 96:7538-7540. (Pubitemid 29299697)
12. Crow TJ. 1993. Sexual selection, Machiavellian intelligence, and the origins of psychosis. Lancet 342:594-598.
13. DeLisi LE, Devoto M, Lofthouse R, Poulter M, Smith A, Shields G, Bass N, Chen G, Vita A, Morgati C, Ott J, Crow TJ. 1994a. Search for linkage to schizophrenia on the X and Y chromosomes. Am J Med Genet 54:113-121.
14. DeLisi LE, Friedrich U, Wahlstrom J, Boccio-Smith A, Forsman A, Eklund K, Crow TJ. 1994b. Schizophrenia and sex chromosome anomalies. Schizophr Bull 20:495-505.
15. Doody GA, Johnstone EC, Sanderson TL, Owens DG, Muir WJ. 1998. 'Pfropfschizophrenie' revisited. Schizophrenia in people with mild learning disability. Br J Psychiatry 173:145-153.
16. Drevets WC. 1999. Prefrontal cortical-amygdalar metabolism in major depression. Ann N Y Acad Sci 877:614-637.
17. Drevets WC, Videen TO, Price JL, Preskorn SH, Carmichael ST, Raichle ME. 1992. A functional anatomical study of unipolar depression. J Neurosci 12:3628-3641.
18. Everman DB, Stoudemire A. 1994. Bipolar disorder associated with Klinefelter's syndrome and other chromosomal abnormalities. Psychosomatics 35:35-40. (Pubitemid 24007050)
19. Geschwind DH, Boone KB, Miller BL, Swerdloff RS. 2000. Neurobehavioral phenotype of Klinefelter syndrome. Ment Retard Dev Disabil Res Rev 6:107-116.
20. Gould E, Woolley CS, Frankfurt M, McEwen BS. 1990. Gonadal steroids regulate dendritic spine density in hippocampal pyramidal cells in adulthood. J Neurosci 10:1286-1291.
21. Harmon RJ, Bender BG, Linden MG, Robinson A. 1998. Transition from adolescence to early adulthood: adaptation and psychiatric status of women with 47,XXX. J Am Acad Child Adolesc Psychiatry 37:286-291. (Pubitemid 28101226)
22. Heaton-Ward A. 1977. Psychosis in mental handicap. The tenth Blake Marsh lecture delivered before the Royal College of Psychiatrists, February 2, 1976. Br J Psychiatry 130:525-533.
23. Kates WR, Abrams MT, Kaufmann WE, Breiter SN, Reiss AL. 1997. Reliability and validity of MRI measurement of the amygdala and hippocampus in children with fragile X syndrome. Psychiatry Res 75:31-48.
24. Kiloh LG, Smith JS. 1978. The neural basis of aggression and its treatment by psychosurgery. Aust N Z J Psychiatry 12:21-28. (Pubitemid 8361515)
25. Kluver H, Bucy PC. 1997. Preliminary analysis of functions of the temporal lobes in monkeys. 1939 [Classical article]. J Neuropsychiatry Clin Neurosci 9:606-620.
26. Kondo Y, Sachs BD, Sakuma Y. 1997. Importance of the medial amygdala in rat penile erection evoked by remote stimuli from estrous females [Corrected and republished in Behav Brain Res 1998;91:215-222]. Behav Brain Res 88:153-160.
27. Kumra S, Jacobsen LK, Lenane M, Zahn TP, Wiggs E, Alaghband-Rad J, Castellanos FX, Frazier JA, McKenna K, Gordon CT, Smith A, Hamburger S, Rapoport JL. 1998. "Multidimensionally impaired disorder": is it a variant of very early-onset schizophrenia? J Am Acad Child Adolesc Psychiatry 37:91-99.
28. Lawrie SM, Abukmeil SS. 1998. Brain abnormality in schizophrenia. A systematic and quantitative review of volumetric magnetic resonance imaging studies. Br J Psychiatry 172:110-120. (Pubitemid 28097708)
29. Lawrie SM, Whalley H, Kestelman JN, Abukmeil SS, Byrne M, Hodges A, Rimmington JE, Best JJ, Owens DG, Johnstone EC. 1999. Magnetic resonance imaging of brain in people at high risk of developing schizophrenia. Lancet 353:30-33. (Pubitemid 29037700)
30. LeDoux JE. 1995. Emotion: clues from the brain. Annu Rev Psychol 46:209-235.
31. Linden MG, Bender BG, Harmon RJ, Mrazek DA, Robinson A. 1988. 47,XXX: what is the prognosis? [published erratum appears in Pediatrics 1989;83:239]. Pediatrics 82:619-630.
32. Mandoki MW, Sumner GS, Hoffman RP, Riconda DL. 1991. A review of Klinefelter's syndrome in children and adolescents [published erratum appears in J Am Acad Child Adolesc Psychiatry 1991;30:516]. J Am Acad Child Adolesc Psychiatry 30:167-172.
33. McCarley RW, Wible CG, Frumin M, Hirayasu Y, Levitt JJ, Fischer IA, Shenton ME. 1999. MRI anatomy of schizophrenia. Biol Psychiatry 45:1099-1119.
34. McEwen BS. 1999. Permanence of brain sex differences and structural plasticity of the adult brain. Proc Natl Acad Sci USA 96:7128-7130.
35. Netley C, Rovet J. 1982. Verbal deficits in children with 47,XXY and 47,XXX karyotypes: a descriptive and experimental study. Brain Lang 17:58-72. (Pubitemid 13249597)
36. Nielsen J, Wohlert M. 1991. Chromosome abnormalities found among 34,910 newborn children: results from a 13-year incidence study in Arhus, Denmark. Hum Genet 87:81-83.
37. Patwardhan AJ, Eliez S, Bender BG, Linden MG, Reiss AL. 2000. Brain morphology in Klinefelter syndrome: extra X chromosome and testosterone supplementation. Neurology 54:2218-2223. (Pubitemid 30416270)
38. Pearlson GD, Barta PE, Powers RE, Menon RR, Richards SS, Aylward EH, Federman EB, Chase GA, Petty RG, Tien AY. 1997. Ziskind-Somerfeld Research Award 1996. Medial and superior temporal gyral volumes and cerebral asymmetry in schizophrenia versus bipolar disorder. Biol Psychiatry 41:1-14.
39. Ratcliffe SG. 1982. The sexual development of boys with the chromosome constitution 47,XXY (Klinefelter's syndrome). Clin Endocrinol Metab 11:703-716. (Pubitemid 13249800)
40. Ratcliffe SG, Tierney I, Nshaho J, Smith L, Springbett A, Callan S. 1982. The Edinburgh study of growth and development of children with sex chromosome abnormalities. Birth Defects Orig Artic Ser 18:41-60. (Pubitemid 13155335)
41. Ratcliffe SG, Masera N, Pan H, McKie M. 1994. Head circumference and IQ of children with sex chromosome abnormalities. Dev Med Child Neurol 36:533-544.
42. Reiss A. 2000. BrainImage®. Stanford, CA.
43. Robinson A, Bender B, Borelli J, Puck M, Salbenblatt J, Webber ML. 1982. Sex chromosomal abnormalities (SCA): a prospective and longitudinal study of newborns identified in an unbiased manner. Birth Defects Orig Artic Ser 18(4):7-39. (Pubitemid 13155334)
44. Sanderson TL, Best JJ, Doody GA, Owens DG, Johnstone EC. 1999. Neuroanatomy of comorbid schizophrenia and learning disability: a controlled study. Lancet 354:1867-1871.
45. Sarrieau A, Mitchell JB, Lal S, Olivier A, Quirion R, Meaney MJ. 1990. Androgen binding sites in human temporal cortex. Neuroendocrinology 51:713-716. (Pubitemid 20194746)
46. Seidman LJ, Faraone SV, Goldstein JM, Goodman JM, Kremen WS, Matsuda G, Hoge EA, Kennedy D, Makris N, Caviness VS, Tsuang MT. 1997. Reduced subcortical brain volumes in nonpsychotic siblings of schizophrenic patients: a pilot magnetic resonance imaging study. AmJ Med Genet 74:507-514. (Pubitemid 27424217)
47. Shenton ME, Kikinis R, Jolesz FA, Pollak SD, LeMay M, Wible CG, Hokama H, Martin J, Metcalf D, Coleman M, McCarley RW. 1992. Abnormalities of the left temporal lobe and thought disorder in schizophrenia. A quantitative magnetic resonance imaging study. N Engl J Med 327:604-612.
48. Simerly RB, Chang C, Muramatsu M, Swanson LW. 1990. Distribution of androgen and estrogen receptor mRNA-containing cells in the rat brain: an in situ hybridization study. J Comp Neurol 294:76-95. (Pubitemid 20104631)
49. Skuse DH, James RS, Bishop DV, Coppin B, Dalton P, Aamodt-Leeper G, Bacarese-Hamilton M, Creswell C, McGurk R, Jacobs PA. 1997. Evidence from Turner's syndrome of an imprinted X-linked locus affecting cognitive function. Nature 387:705-708. (Pubitemid 27270610)
50. Stewart DA, Bailey JD, Netley CT, Rovet J, Park E, Cripps M, Curtis JA. 1982. Growth and development of children with X and Y chromosome aneuploidy from infancy to pubertal age: the Toronto study. Birth Defects Orig Artic Ser 18(4):99-154.
51. Stewart DA, Bailey JD, Netley CT, Rovet J, Park E. 1986. Growth and development from early to midadolescence of children with X and Y chromosome aneuploidy: the Toronto Study. Birth Defects Orig Artic Ser 22(3):119-182. (Pubitemid 17087079)
52. Subramaniam B, Naidu S, Reiss AL. 1997. Neuroanatomy in Rett syndrome: cerebral cortex and posterior fossa. Neurology 48:399-407. (Pubitemid 27087611)
53. Theilgaard A. 1984. A psychological study of the personalities of XYY- and XXY-men. Acta Psychiatr Scand Suppl 315:1-133.
54. Turner G. 1996. Intelligence and the X chromosome. Lancet 347:1814-1815.
55. Walzer S, Wolff PH, Bowen D, Silbert AR, Bashir AS, Gerald PS, Richmond JB. 1978. A method for the longitudinal study of behavioral development in infants and children: the early development of XXY children. J Child Psychol Psychiatry 19:213-229. (Pubitemid 8400238)
56. Walzer S, Bashir AS, Silbert AR. 1991. Cognitive and behavioral factors in the learning disabilities of 47,XXY and 47,XYY boys. Birth Defects Orig Artic Ser 26(4):45-58.
57. Warwick MM, Doody GA, Lawrie SM, Kestelman JN, Best JJ, Johnstone EC. 1999. Volumetric magnetic resonance imaging study of the brain in subjects with sex chromosome aneuploidies. J Neurol Neurosurg Psychiatry 66:628-632.
58. Wright IC, Rabe-Hesketh S, Woodruff PW, David AS, Murray RM, Bullmore ET. 2000. Meta-analysis of regional brain volumes in schizophrenia. Am J Psychiatry 157:16-25. (Pubitemid 30027416)
59. Yokosuka M, Okamura H, Hayashi S. 1997. Postnatal development and sex difference in neurons containing estrogen receptor-alpha immunoreactivity in the preoptic brain, the diencephalon, and the amygdala in the rat. J Comp Neurol 389:81-93. (Pubitemid 27476202)