Liquid-phase microextraction for rapid AP-MALDI and quantitation of nortriptyline in biological matrices

Journal of Separation Science

Volumn 31, Issue 12, 2008, Pages 2288-2294

  Wu, Hui Fen ^a,b   Ku, Hsin Yi ^a   Yen, Jyh Hao ^a,c  

^a NATIONAL SUN YAT SEN UNIVERSITY   (Taiwan)

^b NATIONAL SUN YAT SEN UNIVERSITY   (Taiwan)

^c TAMKANG UNIVERSITY   (Taiwan)

Author keywords

AP MALDI; Human urine; Liquid phase microextraction; Micropipette; MS; Nortriptyline drug

Indexed keywords

ATMOSPHERIC PRESSURE; ATMOSPHERICS; BODY FLUIDS; CHEMOTHERAPY; CONCENTRATION (PROCESS); DRUG DELIVERY; DRUG DOSAGE; EXPERIMENTS; FIBER OPTICS; HOLE CONCENTRATION; LIQUID PHASE EPITAXY; MATRIX ALGEBRA; ORGANIC SOLVENTS; PLASMAS; RATE CONSTANTS; SOLVENT EXTRACTION; TOLUENE;

AGITATION RATES; BIOLOGICAL MATRIXES; BIOLOGICAL SAMPLES; CLINICAL APPLICATIONS; CONCENTRATION (COMPOSITION); CYANO-4-HYDROXYCINNAMIC ACID (CHCA); DETECTION MODES; ENRICHMENT FACTOR (EF); EXTRACTION PROCESSING; EXTRACTION TIME; HOLE SIZE; HOLLOW FIBERS; HUMAN PLASMAS; HUMAN URINE; LINEAR RANGE; LIQUID-PHASE MICROEXTRACTION (LPME); LOW COSTS; MALDI-MS; MICRO SYRINGE; MICRO-PIPETTE; MICROPIPETTE TIPS; MICROPIPETTES; MONITOR (CO); NORTRIPTYLINE; NOVEL METHODS; OPTIMIZED PARAMETERS; POW ERFUL TOOL; QUANTITATIVE DETERMINATIONS; RAPID ANALYSIS; SALT CONCENTRATIONS; SAMPLE PH; SELECTIVE REACTIONS; SINGLE DROP MICRO EXTRACTION (SDME);

EXTRACTION;

ALPHA CYANO 4 HYDROXYCINNAMIC ACID; NORTRIPTYLINE; TOLUENE;

ARTICLE; ATMOSPHERIC PRESSURE; BLOOD ANALYSIS; CONTROLLED STUDY; DRUG DETERMINATION; DRUG STRUCTURE; HOLLOW FIBER; HUMAN; INTERMETHOD COMPARISON; ION MONITORING; LIQUID PHASE MICROEXTRACTION; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MICROPIPETTE; PH MEASUREMENT; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REACTION ANALYSIS; SEPARATION TECHNIQUE; SOLVENT EXTRACTION; SYRINGE; URINALYSIS;

ANTIDEPRESSIVE AGENTS, TRICYCLIC; ATMOSPHERIC PRESSURE; CHEMISTRY, ANALYTICAL; HUMANS; NORTRIPTYLINE; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SOLVENTS; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

EID: 48049118603     PISSN: 16159306     EISSN: 16159314     Source Type: Journal    
DOI: 10.1002/jssc.200700464     Document Type: Article

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