Bioisosteric phentolamine analogs as selective human α2- versus α1-adrenoceptor ligands

European Journal of Pharmacology

Volumn 590, Issue 1-3, 2008, Pages 53-60

  Bavadekar, Supriya A ^a   Hong, Seoung Soo ^c   Lee, Sang II ^d   Miller, Duane D ^e   Feller, Dennis R ^a,b  

^a UNIVERSITY OF MISSISSIPPI   (United States)

^b UNIVERSITY OF MISSISSIPPI   (United States)

^c Chungbuk National University   (South Korea)

^d Keimyung College   (South Korea)

^e UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

Author keywords

2 adrenoceptor; cAMP; G protein coupled receptor; Phentolamine; Radioligand binding assay; Selective 2 adrenoceptor ligand

Indexed keywords

ALPHA 1 ADRENERGIC RECEPTOR; ALPHA 1A ADRENERGIC RECEPTOR; ALPHA 1B ADRENERGIC RECEPTOR; ALPHA 1D ADRENERGIC RECEPTOR; ALPHA 2 ADRENERGIC RECEPTOR; ALPHA 2 ADRENERGIC RECEPTOR BLOCKING AGENT; ALPHA 2A ADRENERGIC RECEPTOR; ALPHA 2B ADRENERGIC RECEPTOR; ALPHA 2C ADRENERGIC RECEPTOR; LUCIFERASE; PHENTOLAMINE;

ANIMAL CELL; ARTICLE; CELL STRAIN HEK293; CHO CELL; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; LIPOPHILICITY; METHYLATION; NONHUMAN; PRIORITY JOURNAL; RECEPTOR AFFINITY; REPORTER GENE;

ANIMALS; CHO CELLS; CRICETINAE; CRICETULUS; CYCLIC AMP; HUMANS; LUCIFERASES; PHENTOLAMINE; RADIOLIGAND ASSAY; RECEPTORS, ADRENERGIC, ALPHA-1; RECEPTORS, ADRENERGIC, ALPHA-2; RESPONSE ELEMENTS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 48049118329     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2008.05.027     Document Type: Article

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