The association between heart rate variability and cognitive impairment in middle-aged men and women: The Whitehall II cohort study

Neuroepidemiology

Volumn 31, Issue 2, 2008, Pages 115-121

  Britton, Annie ^a   Singh Manoux, Archana ^a,c   Hnatkova, Katerina ^b   Malik, Marek ^b   Marmot, Michael G ^a   Shipley, Martin ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

^c HÔPITAL PAUL BROUSSE   (France)

Author keywords

Autonomic function; Cognitive impairment; Cohort studies; Heart rate variability

Indexed keywords

ADULT; AGED; ARTICLE; COGNITION; COGNITIVE DEFECT; COHORT ANALYSIS; FEMALE; HEART RATE VARIABILITY; HUMAN; LINGUISTICS; MALE; MEMORY; MIDDLE AGED; PHONEME; POPULATION; SEMANTICS; UNITED KINGDOM;

ADULT; COGNITION DISORDERS; COHORT STUDIES; CROSS-SECTIONAL STUDIES; FEMALE; FOLLOW-UP STUDIES; GREAT BRITAIN; HEART RATE; HUMANS; LONGITUDINAL STUDIES; MALE; MIDDLE AGED; NEUROPSYCHOLOGICAL TESTS; PROSPECTIVE STUDIES;

EID: 48049116886     PISSN: 02515350     EISSN: None     Source Type: Journal    
DOI: 10.1159/000148257     Document Type: Article

References (35)

1. Morris JC, Storandt M, Miller JP, McKeel DW, Price JL, Rubin EH, et al: Mild cognitive impairment represents early-stage Alzheimer disease. Arch Neurol 2001;58:397-405.
2. Chertkow H: Mild cognitive impairment. Curr Opin Neurol 2002;15:401-407.
3. Fried LP, Kronmal RA, Newman AB, et al: Risk factors for 5-year mortality in older adults. JAMA 1998;279:585-592.
4. Bassuk SS, Wyppij D, Berkman LF: Cognitive impairment and mortality in the community-dwelling elderly. Am J Epidemiol 2000;151:676-688.
5. Kuh D, Richards M, Hardy R, et al: Childhood cognitive ability and deaths up until middle age: a post-war birth cohort study. Int J Epidemiol 2004;33:408-413.
6. Graham JE, Rockwood K, Beattie BL, et al: Prevalence and severity of cognitive impairment with and without dementia in an elderly population. Lancet 1997;349:1793-1796.
7. Holland CA, Rabbitt P: The course and causes of cognitive change with advancing age. Rev Clin Gerontol 1991;1:81-96.
8. Singh-Manoux A, Britton A, Marmot M: Vascular disease and cognitive function: evidence from the Whitehall II study. J Am Geriatr Soc 2003;51:1445-1450.
9. Singh-Manoux A, Britton A, Kivimaki M, Gueguen A, Halcox J, Marmot M: Socioeconomic status moderates the association between carotid intima-media thickness and cognition in midlife: evidence from the Whitehall II Study. Atherosclerosis 2008;197:541-548.
10. Singh-Manoux A, Marmot M: High blood pressure was associated with cognitive function in middle-age in the Whitehall II study. J Clin Epidemiol 2005;58:1308-1315.
11. Britton A, Singh-Manoux A, Marmot M: Alcohol consumption and cognitive function in the Whitehall II study. Am J Epidemiol 2004;160:240-247.
12. Singh-Manoux A, Hillsdon M, Brunner E, Marmot M: Effects of physical activity on cognitive functioning in middle-age: evidence from the Whitehall II prospective cohort study. Am J Public Health 2005;95:2252-2258.
13. Aronson MK, Ooi WL, Morgenstern H, et al: Women, myocardial infarction, and dementia in the very old. Neurology 1990;40:1102-1106.
14. Muller M, Grobbee DE, Aleman A, et al: Cardiovascular disease and cognitive performance in middle-aged and elderly men. Atherosclerosis 2007;190:143-149.
15. Liao D, Cai J, Barnes RW, et al: Association of cardiac autonomic function and the development of hypertension: the ARIC study. Am J Hypertens 1996;9:1147-1156.
16. Thayer JF, Lane RD: The role of vagal function in the risk for cardiovascular disease and mortality. Biol Psychobiol 2007;74:224-242.
17. Britton A, Shipley M, Malik M, Hnatkova K, Hemingway H, Marmot M: Changes in heart rate and heart rate variability over time in middle-aged men and women in the general population (from the Whitehall II Cohort Study). Am J Cardiol 2007;100:524-527.
18. Liao D, Cai J, Rosamond WD, Barnes RW, Hutchinson RG, Whitsel EA, et al: Cardiac autonomic function and incident coronary heart disease: a population-based case-cohort study. The ARIC Study: Atherosclerosis Risk in Communities Study. Am J Epidemiol 1997;145:696-706.
19. Kleiger RE, Miller JP, Bigger JT Jr, Moss AJ: Decreased heart rate variability and its association with increased mortality after acute myocardial infarction. Am J Cardiol 1987;59:256-262.
20. Farrell TG, Bashir Y, Cripps T, Malik M, Poloniecki J, Bennett ED, et al: Risk stratification for arrhythmic events in postinfarction patients based on heart rate variability, ambulatory electrocardiographic variables and the signal-averaged electrocardiogram. J Am Coll Cardiol 1991;18:687-697.
21. Bigger JT Jr, Fleiss JL, Steinman RC, Rolnitzky LM, Kleiger RE, Rottman JN, et al: Frequency domain measures of heart period variability and mortality after myocardial infarction. Circulation 1992;85:164-171.
22. Moroney JT, Tang MX, Berglund L, Small S, Merchant C, Bell K, et al: Low-density lipoprotein cholesterol and the risk of dementia with stroke. JAMA 1999;282:254-260.
23. Karlamangla AS, Singer BH, Chodosh J, McEwen BS, Seeman TE: Urinary cortisol excretion as a predictor of incident cognitive impairment. Neurobiol Aging 2005;26(suppl 1):80-84.
24. Kim DH, Lipsitz LA, Ferrucci L, Varadhan R, Guralnik JM, Carlson MC, et al: Association between reduced heart rate variability and cognitive impairment in older disable women in the community: Women's Health and Aging Study I. J Am Geratr Soc 2006;554:1751-1757.
25. Zulli R, Nicosia F, Borroni B, Agostil C, Prometti P, Donati P, et al: QT dispersion and heart rate variability abnormalities in Alzheimer's disease and in mild cognitive impairment. J Am Geriatr Soc 2005;53:2135-2139.
26. Marmot MG, Davey Smith G, Stansfeld S, Patel C, North F, Head J, et al: Health inequalities among British civil servants: the Whitehall II study. Lancet 1991;337:1387-1393
27. Marmot M, Brunner E: Cohort profile: The Whitehall II Study. Int J Epidemiol 2005;34:251-256.
28. Heim AW: AH4 group test of general intelligence ASE. Windsor, NFER-Nelson, 1970.
29. Raven JC: Guide to Using the Mill Hill Vocabulary Scale with Progressive Matrices. London, HK Lewis, 1965.
30. Borkowski JG, Benton AL, Spreen O: Word fluency and brain damage. Neuropsychologica 1967;5:135-140.
31. Kivipelto M, Ngandu T, Laatikainen T, Winblad B, Soininen H, Tuomilehto J, et al: Risk score for the prediction of dementia risk in 20 years among middle aged people: a longitudinal, population-based study. Lancet Neurol 2006;5:735-741.
32. Anstey KJ, Luszcz MA, Giles LC, Andrews GR: Demographic, health, cognitive, and sensory variables as predictors of mortality in very old adults. Psychol Aging 2001;16:3-11.
33. Allan LM, Kerr SR, Ballard CG, Allen J, Murray A, McLaren AT, Kenny RA: Autonomic function assessed by heart rate variability is normal in Alzheimer's disease and vascular dementia. Dement Geriatr Cogn Disord 2005;19:140-144.
34. Murakami S, Yamanaka T, Kubo Y, Wada T, Yano S, Nighimura Y, et al: Heart rate variability analysis and neurobehavioral function in community-dwelling older people aged 75 or older. Nippon Ronen Igakkai Zasshi 2002;39:520-526.
35. Bauer A, Kantelhardt JW, Barthel P, Schneider R, Mäkikallio T, Ulm K, Hnatkova K, Schömig A, Huikuri H, Bunde A, Malik M, Schmidt G: Deceleration capacity of heart rate as a predictor of mortality after myocardial infarction: cohort study. Lancet 2006;367:1674-1681.