High-producing MBL2 genotypes increase the risk of acute and chronic carditis in patients with history of rheumatic fever

Molecular Immunology

Volumn 45, Issue 14, 2008, Pages 3827-3831

  Schafranski, Marcelo Derbli ^a   Pereira Ferrari, Lílian ^a   Scherner, Daniela ^a   Torres, Renato ^b   Jensenius, Jens Christian ^c   de Messias Reason, Iara José ^a  

^a FEDERAL UNIVERSITY OF PARANÁ   (Brazil)

^b HOSPITAL PEQUENO PRÍNCIPE   (Brazil)

^c AARHUS UNIVERSITY   (Denmark)

Author keywords

Carditis; Complement; Mannan binding lectin; Rheumatic fever; Rheumatic heart disease

Indexed keywords

MANNOSE BINDING LECTIN 2;

ADOLESCENT; ADULT; AGED; ARTICLE; CARDITIS; CLINICAL FEATURE; CONTROLLED STUDY; EXON; FEMALE; GENETIC POLYMORPHISM; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROMOTER REGION; RHEUMATIC FEVER; RISK FACTOR; SCHOOL CHILD;

ACUTE DISEASE; ADOLESCENT; ADULT; AGED; CASE-CONTROL STUDIES; CHILD; CHRONIC DISEASE; EXONS; FEMALE; GENOTYPE; HUMANS; MALE; MANNOSE-BINDING LECTIN; MIDDLE AGED; MYOCARDITIS; POLYMORPHISM, GENETIC; PROMOTER REGIONS, GENETIC; RHEUMATIC FEVER; RISK FACTORS;

STREPTOCOCCUS; STREPTOCOCCUS PYOGENES;

EID: 48049112799     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molimm.2008.05.013     Document Type: Article

References (20)

1. Chiu Y.Y., Hayashi M., Schafranski M., and Messias-Reason I.J.T. Further evidence of inflammation in chronic rheumatic valve disease (CRVD): high levels of advanced oxidation protein products (AOPP) and high sensitive C-reactive protein (hs-CRP). Int. J. Cardiol. 109 (2006) 275-276
2. Davutoglu V., Celik A., and Aksoy M. Contribution of selected serum inflammatory mediators to the progression of chronic rheumatic valve disease, subsequent valve calcification and NYHA functional class. J. Heart Valve Dis. 14 (2005) 251-256
3. Dornelles L.N., Pereira-Ferrari L., and Messias-Reason I. Mannan-binding lectin plasma levels in leprosy: deficiency confers protection against the lepromatous but not the tuberculoid forms. Clin. Exp. Immunol. 145 3 (2006) 463-468
4. Guilherme L., Ramasawmy R., and Kalil J. Rheumatic fever and rheumatic heart disease: genetics and pathogenesis. Scand. J. Immunol. 66 (2007) 199-207
5. Gibofsky A., and Zabriskie Z. Rheumatic fever: etiology, diagnosis and treatment. In: Koopman J. (Ed). Arthritis and Allied Conditions (2001), Lippincott Williams and Wilkins, Philadelphia 1761-1773
6. Jack D.L., Read R.C., Tenner A.J., et al. Mannose-binding lectin regulates the inflammatory response of human professional phagocytes to Neisseria meningitidis serogroup B. J. Infect. Dis. 184 9 (2001) 1152-1162
7. Jordan J.E., Montalto M.C., and Stahl G.L. Inhibition of mannose-binding lectin reduces postischemic myocardial reperfusion injury. Circulation 104 (2003) 1413-1418
8. Kumar V., Ganguly N.K., Anand I.S., et al. NADPH oxidase activity in the monocytes and neutrophils of patients with rheumatic fever. Cardioscience 2 2 (1991) 93-97
9. Lahiri D.K., and Nurnberger J.R. A rapid non-enzymatic method for the preparation of HMW DNA from blood for RFLP studies. Nucleic Acids Res. 19 19 (1991) 5444
10. Messias Reason I.J., Schafranski M.D., Jensenius J.C., et al. The association between mannose-binding lectin gene polymorphism and rheumatic heart disease. Hum. Immunol. 7 12 (2006) 991-998
11. Messias Reason I.J., Boldt A.B., Moraes Braga A.C., et al. The association between mannan-binding lectin gene polymorphism and clinical leprosy: new insight into an old paradigm. J. Infect. Dis. 196 9 (2007) 1379-1385
12. Nayar S., Nayar P.G., and Cherian K.M. Heart valve structure: a predisposing factor for rheumatic heart disease. Heart 92 8 (2006) 1151-1152
13. Rugonfalvi-Kiss S., Dósa E., Madsen H.O., et al. High rate of early restenosis after carotid eversion endarterectomy in homozygous carriers of the normal mannose-binding lectin genotype. Stroke 36 (2005) 944-948
14. Saevarsdottir S., Steinsson K., and Ludviksson B.R. Mannan-binding lectin may facilitate the clearance of circulating immune complexes-implications from a study on C2-deficient individuals. Clin. Exp. Immunol. 148 2 (2007) 248-253
15. Santos I.K., Costa C.H., Krieger H., et al. Mannan-binding lectin enhances susceptibility to visceral leishmaniasis. Infect. Immun. 69 8 (2001) 5212-5215
16. Schafranski M.D., Stier A., Nisihara R., et al. Significantly increased levels of mannose-binding lectin (MBL) in rheumatic heart disease: a beneficial role for MBL deficiency. Clin. Exp. Immunol. 138 3 (2004) 521-525
17. Steffensen R., Thiel S., Varming K., et al. Detection of structural gene mutations and promoter polymorphisms in the mannan-binding lectin (MBL) gene by polymerase chain with sequence-specific primers. J. Immunol. Methods 241 (2000) 33-42
18. Svartman M., Potter E.V., Poon-King T., et al. Immunoglobulins and complement components in synovial fluid of patients with acute rheumatic fever. J. Clin. Invest. 56 1 (1975) 111-117
19. Takahashi K., Ip W.K.E., Michelow I.C., et al. The mannose-binding lectin: a prototypic pattern recognition molecule. Curr. Opin. Immun. 18 (2006) 16-23
20. Troelsen L.N., Garred P., Madsen H.O., et al. Genetically determined high serum levels of mannose-binding lectin and agalactosyl IgG are associated with isquemic heart disease in rheumatoid arthritis. Arthritis Rheum. 56 (2007) 21-29