-
1
-
-
0036810246
-
Design, activity, and structure of a highly specific artificial endonuclease
-
Chevalier BS, Kortemme T, Chadsey MS, et al. Design, activity, and structure of a highly specific artificial endonuclease. Mol Cell 2002;10:895-905
-
(2002)
Mol Cell
, vol.10
, pp. 895-905
-
-
Chevalier, B.S.1
Kortemme, T.2
Chadsey, M.S.3
-
2
-
-
0025757012
-
Engineering subtilisin and its substrates for efficient ligation of peptide bonds in aqueous solution
-
Abrahmsen L, Tom J, Burnier J, et al. Engineering subtilisin and its substrates for efficient ligation of peptide bonds in aqueous solution. Biochem 1991;30:4151-9
-
(1991)
Biochem
, vol.30
, pp. 4151-4159
-
-
Abrahmsen, L.1
Tom, J.2
Burnier, J.3
-
3
-
-
0025074907
-
In vitro selection of RNA molecules that bind specific ligands
-
Ellington AD, Szostak JW. In vitro selection of RNA molecules that bind specific ligands. Nature 1990;346:818-22
-
(1990)
Nature
, vol.346
, pp. 818-822
-
-
Ellington, A.D.1
Szostak, J.W.2
-
4
-
-
0025194307
-
Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase
-
Tuerk C, Gold L. Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase. Science 1990;249:505-10
-
(1990)
Science
, vol.249
, pp. 505-510
-
-
Tuerk, C.1
Gold, L.2
-
5
-
-
0025332385
-
Selection in vitro of an RNA enzyme that specifically cleaves single-stranded DNA
-
Robertson DL, Joyce GF. Selection in vitro of an RNA enzyme that specifically cleaves single-stranded DNA. Nature 1990;344:467-8
-
(1990)
Nature
, vol.344
, pp. 467-468
-
-
Robertson, D.L.1
Joyce, G.F.2
-
6
-
-
34548528158
-
Progress in computational protein design
-
Lippow SM, Tidor B. Progress in computational protein design. Curr Opin Biotechnol 2007;18:305-11
-
(2007)
Curr Opin Biotechnol
, vol.18
, pp. 305-311
-
-
Lippow, S.M.1
Tidor, B.2
-
7
-
-
23444450226
-
Semi-rational approaches to engineering enzyme activity: Combining the benefits of directed evolution and rational design
-
Chica RA, Doucet N, Pelletier JN. Semi-rational approaches to engineering enzyme activity: combining the benefits of directed evolution and rational design. Curr Opin Biotechnol 2005;16:378-84
-
(2005)
Curr Opin Biotechnol
, vol.16
, pp. 378-384
-
-
Chica, R.A.1
Doucet, N.2
Pelletier, J.N.3
-
8
-
-
0032853242
-
In vitro selection of functional nucleic acids
-
Wilson DS, Szostak JW. In vitro selection of functional nucleic acids. Annu Rev Biochem 1999;68:611-47
-
(1999)
Annu Rev Biochem
, vol.68
, pp. 611-647
-
-
Wilson, D.S.1
Szostak, J.W.2
-
9
-
-
0000917638
-
In vitro selection of catalytic polynucleotides
-
Breaker RR. In vitro selection of catalytic polynucleotides. Chem Rev 1997;97:371-90
-
(1997)
Chem Rev
, vol.97
, pp. 371-390
-
-
Breaker, R.R.1
-
10
-
-
0023647382
-
Towards a general theory of adaptive walks on rugged landscapes
-
Kauffman S, Levin S. Towards a general theory of adaptive walks on rugged landscapes. J Theor Biol 1987; 128:11-45
-
(1987)
J Theor Biol
, vol.128
, pp. 11-45
-
-
Kauffman, S.1
Levin, S.2
-
11
-
-
0014935646
-
Natural selection and the concept of a protein space
-
Smith JM. Natural selection and the concept of a protein space. Nature 1970;225:563-4
-
(1970)
Nature
, vol.225
, pp. 563-564
-
-
Smith, J.M.1
-
12
-
-
0037665961
-
Functional information: Molecular messages
-
Szostak JW. Functional information: molecular messages. Nature 2003;423:689
-
(2003)
Nature
, vol.423
, pp. 689
-
-
Szostak, J.W.1
-
13
-
-
0030030533
-
Smoothness within ruggedness: The role of neutrality in adaptation
-
Huynen MA, Stadler PF, Fontana W Smoothness within ruggedness: the role of neutrality in adaptation. Proc Natl Acad Sci USA 1996;93:397-401
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 397-401
-
-
Huynen, M.A.1
Stadler, P.F.2
Fontana, W.3
-
14
-
-
47949126047
-
-
Arnold FH, Georgiou G. Directed evolution library creation: methods and protocols Humana Press, Inc.: Totowa; 2003. p. 231
-
Arnold FH, Georgiou G. Directed evolution library creation: methods and protocols Humana Press, Inc.: Totowa; 2003. p. 231
-
-
-
-
15
-
-
85045502002
-
Randomization of genes by PCR mutagenesis.PCR Methods Applications
-
Cadwell RC, Joyce GF. Randomization of genes by PCR mutagenesis.PCR Methods Applications 1992;2:28-33
-
(1992)
, vol.2
, pp. 28-33
-
-
Cadwell, R.C.1
Joyce, G.F.2
-
17
-
-
55849103128
-
Structural insights into the evolution of a non-biological protein: Importance of surface residues in protein fold optimization. PLoS One 2007;e467
-
23 May, doi: 10.1371 /journal.pone.0000467
-
Smith MD, Rosenow MA, Wang M, et al. Structural insights into the evolution of a non-biological protein: importance of surface residues in protein fold optimization. PLoS One 2007;e467. Published online 23 May 2007, doi: 10.1371 /journal.pone.0000467
-
(2007)
Published online
-
-
Smith, M.D.1
Rosenow, M.A.2
Wang, M.3
-
18
-
-
47949100975
-
-
Humana Press, Inc, Totowa;
-
Fenton C, Xu H, Petersen EI, et al. Methods in molecular biology: in vitro mutagenesis protocols. Humana Press, Inc.: Totowa; 2004. p. 234
-
(2004)
Methods in molecular biology: In vitro mutagenesis protocols
, pp. 234
-
-
Fenton, C.1
Xu, H.2
Petersen, E.I.3
-
19
-
-
0023473632
-
The use of random-sequence oligonucleotides for determining consensus sequences
-
Oliphant AR, Struhl K. The use of random-sequence oligonucleotides for determining consensus sequences. Merhods Enzymol 1987;155:568-81
-
(1987)
Merhods Enzymol
, vol.155
, pp. 568-581
-
-
Oliphant, A.R.1
Struhl, K.2
-
20
-
-
0023949179
-
Combinatorial cassette muragenesis as a probe of the informational content of protein sequences
-
Reidhaar-Olson JF, Sauer RT. Combinatorial cassette muragenesis as a probe of the informational content of protein sequences. Science 1988;241:53-7
-
(1988)
Science
, vol.241
, pp. 53-57
-
-
Reidhaar-Olson, J.F.1
Sauer, R.T.2
-
21
-
-
0001586362
-
Identifying determinants of folding and activity for a prorein of unknown structure
-
Bowie JU, Sauer RT. Identifying determinants of folding and activity for a prorein of unknown structure. Proc Natl Acad Sci USA 1989;86:2152-6
-
(1989)
Proc Natl Acad Sci USA
, vol.86
, pp. 2152-2156
-
-
Bowie, J.U.1
Sauer, R.T.2
-
22
-
-
0028110130
-
DNA shuffling by random fragmenrarion and reassembly: In virro recombination for molecular evolurion
-
Stemmer WPC. DNA shuffling by random fragmenrarion and reassembly: in virro recombination for molecular evolurion. Proc Natl Acad Sci USA 1994;91:10747-51
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 10747-10751
-
-
Stemmer, W.P.C.1
-
23
-
-
0032518266
-
DNA shuffling of a family of genes from diverse species accelerates directed evolution
-
Crameri A, Raillard S-A, Bermudez E, Stemmer WPC. DNA shuffling of a family of genes from diverse species accelerates directed evolution. Nature 1998;391:288-91
-
(1998)
Nature
, vol.391
, pp. 288-291
-
-
Crameri, A.1
Raillard, S.-A.2
Bermudez, E.3
Stemmer, W.P.C.4
-
24
-
-
0029670330
-
Improved green fluorescenr prorein by molecular evolurion using DNA shuffling
-
Crameri A, Whitehorn EA, Tate E, Stemmer WPC. Improved green fluorescenr prorein by molecular evolurion using DNA shuffling. Nat Biotechnol 1996;14:315-9
-
(1996)
Nat Biotechnol
, vol.14
, pp. 315-319
-
-
Crameri, A.1
Whitehorn, E.A.2
Tate, E.3
Stemmer, W.P.C.4
-
25
-
-
0030989062
-
Directed evolution of a fucosidase from a galactosidase by DNA shuffling and screening
-
Zhang J-H, Dawes G, Stemmer WPC. Directed evolution of a fucosidase from a galactosidase by DNA shuffling and screening. Proc Natl Acad Sci USA 1997;94:4504-9
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 4504-4509
-
-
Zhang, J.-H.1
Dawes, G.2
Stemmer, W.P.C.3
-
26
-
-
0031909113
-
Molecular evolution by staggered extension process (StEP) in vitro recombination
-
Zhao HM, Giver L, Shao ZX, et al. Molecular evolution by staggered extension process (StEP) in vitro recombination. Nar Biorechnol 1998;16:258-61
-
(1998)
Nar Biorechnol
, vol.16
, pp. 258-261
-
-
Zhao, H.M.1
Giver, L.2
Shao, Z.X.3
-
27
-
-
0035949702
-
Creating multiple-crossover DNA libraries independenr of sequence identity
-
Lurz S, Ostermeier M, Moore GL, er al. Creating multiple-crossover DNA libraries independenr of sequence identity. Proc Natl Acad Sci USA 2001 ;98:11248-53
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 11248-11253
-
-
Lurz, S.1
Ostermeier, M.2
Moore, G.L.3
er al4
-
28
-
-
17444363724
-
A combinarorial approach ro hybrid enzymes independent of DNA homology
-
Ostermeier M, Shim JH, Benkovic SJ. A combinarorial approach ro hybrid enzymes independent of DNA homology. Nat Biotechnol 1999;17:1205-9
-
(1999)
Nat Biotechnol
, vol.17
, pp. 1205-1209
-
-
Ostermeier, M.1
Shim, J.H.2
Benkovic, S.J.3
-
29
-
-
0036788537
-
Nucleic acid evolution and minimization by nonhomologous random recombination
-
Bittker JA, Le BV, Liu DR. Nucleic acid evolution and minimization by nonhomologous random recombination. Nat Biotechnol 2002;20:1024-9
-
(2002)
Nat Biotechnol
, vol.20
, pp. 1024-1029
-
-
Bittker, J.A.1
Le, B.V.2
Liu, D.R.3
-
30
-
-
2342642643
-
Directed evolution of protein enzymes using nonhomologous random recombination
-
Bittker JA, Le BV, Liu JM, Liu DR. Directed evolution of protein enzymes using nonhomologous random recombination. Proc Narl Acad Sci USA 2004;101:7011-6
-
(2004)
Proc Narl Acad Sci USA
, vol.101
, pp. 7011-7016
-
-
Bittker, J.A.1
Le, B.V.2
Liu, J.M.3
Liu, D.R.4
-
31
-
-
0037011406
-
Screening and selection methods for large-scale analysis of prorein function
-
Lin H, Cornish VW. Screening and selection methods for large-scale analysis of prorein function. Angew Chem Int Ed 2002;41:4402-25
-
(2002)
Angew Chem Int Ed
, vol.41
, pp. 4402-4425
-
-
Lin, H.1
Cornish, V.W.2
-
32
-
-
34250316583
-
Flow cytometric analysis of DNA binding and cleavage by cell surface-displayed homing endonucleases
-
Volna P, Jarjour J, Baxrer S, et al. Flow cytometric analysis of DNA binding and cleavage by cell surface-displayed homing endonucleases. Nucleic Acids Res 2007;35:2748-58
-
(2007)
Nucleic Acids Res
, vol.35
, pp. 2748-2758
-
-
Volna, P.1
Jarjour, J.2
Baxrer, S.3
-
33
-
-
0035424822
-
Protein engineering by cell surface display
-
Wittrup KD. Protein engineering by cell surface display. Curr Opin Biotechnol 2001;12:395-9
-
(2001)
Curr Opin Biotechnol
, vol.12
, pp. 395-399
-
-
Wittrup, K.D.1
-
36
-
-
0033987925
-
Exploiting recombination in single bacteria ro make large phage antibody libraries
-
Sblattero D, Bradbury A. Exploiting recombination in single bacteria ro make large phage antibody libraries. Nar Biotechnol 2000;18:75-80
-
(2000)
Nar Biotechnol
, vol.18
, pp. 75-80
-
-
Sblattero, D.1
Bradbury, A.2
-
37
-
-
0032168985
-
A method for directed evolution and functional cloning of enzymes
-
Pedersen H, Holder S, Surherlin DP, et al. A method for directed evolution and functional cloning of enzymes. Proc Narl Acad Sci USA 1998;95:10523-8
-
(1998)
Proc Narl Acad Sci USA
, vol.95
, pp. 10523-10528
-
-
Pedersen, H.1
Holder, S.2
Surherlin, D.P.3
-
38
-
-
0028592703
-
An in virro polysome display sysrem for identifying ligands from very large peptide libraries
-
Marrheakis LC, Bhart RR, Dower WJ. An in virro polysome display sysrem for identifying ligands from very large peptide libraries. Proc Narl Acad Sci USA 1994;91:9022-6
-
(1994)
Proc Narl Acad Sci USA
, vol.91
, pp. 9022-9026
-
-
Marrheakis, L.C.1
Bhart, R.R.2
Dower, W.J.3
-
39
-
-
0031021109
-
Functional antibody production using cell-free translation: Effects of protein disulfide isomerase and chaperones
-
Ryabova LA, Desplancq D, Spirin AS, Pliickthun A. Functional antibody production using cell-free translation: effects of protein disulfide isomerase and chaperones. Nat Biorechnol 1997;15:79-84
-
(1997)
Nat Biorechnol
, vol.15
, pp. 79-84
-
-
Ryabova, L.A.1
Desplancq, D.2
Spirin, A.S.3
Pliickthun, A.4
-
40
-
-
0037196286
-
A novel straregy by rhe action of ricin rhat connects phenotype and genotype without loss of the diversity of libraries
-
Zhou JM, Fujira S, Warashina M, et al.A novel straregy by rhe action of ricin rhat connects phenotype and genotype without loss of the diversity of libraries. J Am Chem Soc 2002;124:538-43
-
(2002)
J Am Chem Soc
, vol.124
, pp. 538-543
-
-
Zhou, J.M.1
Fujira, S.2
Warashina, M.3
-
41
-
-
0036603593
-
In vitro selection as a powerful tool for the applied evolution of proteins and peptides
-
Dower WJ, Mattheakis LC. In vitro selection as a powerful tool for the applied evolution of proteins and peptides. Curr Opin Chem Biol 2002;6:390-8
-
(2002)
Curr Opin Chem Biol
, vol.6
, pp. 390-398
-
-
Dower, W.J.1
Mattheakis, L.C.2
-
42
-
-
0030817279
-
RNA-peptide fusions for the in vitro selection of peptides and proreins
-
Roberts RW, SzostakJW. RNA-peptide fusions for the in vitro selection of peptides and proreins. Proc Natl Acad Sci USA 1997;94:12297-302
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 12297-12302
-
-
Roberts, R.W.1
SzostakJW2
-
45
-
-
0031854986
-
Man-made cell-like compartments for molecular evolurion
-
Tawfik DS, Griffirhs AD. Man-made cell-like compartments for molecular evolurion. Nar Biotechnol 1998;16:652-6
-
(1998)
Nar Biotechnol
, vol.16
, pp. 652-656
-
-
Tawfik, D.S.1
Griffirhs, A.D.2
-
47
-
-
0042432086
-
Direcred evolution of industrial enzymes: An update
-
Cherry JR, Fidanrsef AL. Direcred evolution of industrial enzymes: an update. Curr Opin Biotechnol 2003;14:438-43
-
(2003)
Curr Opin Biotechnol
, vol.14
, pp. 438-443
-
-
Cherry, J.R.1
Fidanrsef, A.L.2
-
48
-
-
3543087310
-
Trends and innovations in industrial biocatalysis for rhe production of fine chemicals
-
Panke S, Held M, Wubbolts M. Trends and innovations in industrial biocatalysis for rhe production of fine chemicals. Curr Opin Biotechnol 2004;15:272-9
-
(2004)
Curr Opin Biotechnol
, vol.15
, pp. 272-279
-
-
Panke, S.1
Held, M.2
Wubbolts, M.3
-
49
-
-
0035843170
-
Industrial biocatalysis today and tomorrow
-
Schimd A, Dordick JS, Hauer B, er al. Industrial biocatalysis today and tomorrow. Nature 2001;409:258-68
-
(2001)
Nature
, vol.409
, pp. 258-268
-
-
Schimd, A.1
Dordick, J.S.2
Hauer, B.3
er al4
-
50
-
-
33947216799
-
Diversification of catalytic function in a synthetic family of chimeric cytochrome P450s
-
Landwehr M, Carbone M, Orey CR, et al. Diversification of catalytic function in a synthetic family of chimeric cytochrome P450s. Chem Bio 2007;14:269-78
-
(2007)
Chem Bio
, vol.14
, pp. 269-278
-
-
Landwehr, M.1
Carbone, M.2
Orey, C.R.3
-
51
-
-
26944470771
-
Direct conversion of ethane to ethanol by engineered cyrochrome P450 BM3
-
Meinhold P, Peters MW, Chen MMV, et al. Direct conversion of ethane to ethanol by engineered cyrochrome P450 BM3. ChemBioChem 2005;6:1765-8
-
(2005)
ChemBioChem
, vol.6
, pp. 1765-1768
-
-
Meinhold, P.1
Peters, M.W.2
Chen, M.M.V.3
-
52
-
-
33645833425
-
-
Meinhold P, Peters MW, Harrwick A,er al. Engineering cytochrome P450 BM3 for terminal alkane hydroxylation. Adv Synth Catal 2006;348:763-72
-
Meinhold P, Peters MW, Harrwick A,er al. Engineering cytochrome P450 BM3 for terminal alkane hydroxylation. Adv Synth Catal 2006;348:763-72
-
-
-
-
53
-
-
31344438135
-
Enantioselective epoxidation of terminal alkenes ro (R)- and (S)-epoxides by engineered cytochromes P450 BM-3
-
Kubo T, Peters MW, Meinhold P, Arnold FH. Enantioselective epoxidation of terminal alkenes ro (R)- and (S)-epoxides by engineered cytochromes P450 BM-3. Chem Eur J 2006;12:1216-20
-
(2006)
Chem Eur J
, vol.12
, pp. 1216-1220
-
-
Kubo, T.1
Peters, M.W.2
Meinhold, P.3
Arnold, F.H.4
-
54
-
-
0037076311
-
Directed evolution of novel polymerase acrivities: Mutation of a DNA polymerase into an efficient RNA polymerase
-
Xia G, Chen L, Sera T, er al. Directed evolution of novel polymerase acrivities: mutation of a DNA polymerase into an efficient RNA polymerase. Proc Narl Acad Sci USA 2002;99:6597-602
-
(2002)
Proc Narl Acad Sci USA
, vol.99
, pp. 6597-6602
-
-
Xia, G.1
Chen, L.2
Sera, T.3
er al4
-
55
-
-
31544477181
-
Design and evolurion of new catalytic activity with an existing protein scaffold
-
Park H-S, Nam S-H, Lee JK, er al. Design and evolurion of new catalytic activity with an existing protein scaffold. Science 2006;311:535-8
-
(2006)
Science
, vol.311
, pp. 535-538
-
-
Park, H.-S.1
Nam, S.-H.2
Lee, J.K.3
er al4
-
56
-
-
37549032160
-
Combinatorial synthesis of peptide arrays onto a microchip
-
Beyer M, Nesterov A, Block I, et al. Combinatorial synthesis of peptide arrays onto a microchip. Science 2007;318:1888
-
(2007)
Science
, vol.318
, pp. 1888
-
-
Beyer, M.1
Nesterov, A.2
Block, I.3
-
58
-
-
33745633570
-
A genetically encoded fluorescent amino acid
-
Summerer D, Chen S, Wu N, et al. A genetically encoded fluorescent amino acid. Proc Natl Acad Sci USA 2006;103:9785-9
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 9785-9789
-
-
Summerer, D.1
Chen, S.2
Wu, N.3
-
61
-
-
43049128964
-
An expanded set of amino acid analogs for the ribosomal translation of unnatural peptides. PLoS One 2007;e972
-
3 October, doi: 10.1371 /journal.pone.0000972
-
Hartman MCT, Josephson K, Lin C-W Szostak J W. An expanded set of amino acid analogs for the ribosomal translation of unnatural peptides. PLoS One 2007;e972. Published online 3 October 2007, doi: 10.1371 /journal.pone.0000972
-
(2007)
Published online
-
-
Hartman, M.C.T.1
Josephson, K.2
Lin, C.-W.3
Szostak, J.W.4
-
63
-
-
0022991435
-
Selective chemical catalysis by an antibody
-
Pollack SJ, Jacobs JW, Schultz PG. Selective chemical catalysis by an antibody. Science 1986;234:1570-3
-
(1986)
Science
, vol.234
, pp. 1570-1573
-
-
Pollack, S.J.1
Jacobs, J.W.2
Schultz, P.G.3
-
65
-
-
0033791659
-
Critical analysis of antibody catalysis
-
Hilvert D. Critical analysis of antibody catalysis. Ann Rev Biochem 2000;69:751-93
-
(2000)
Ann Rev Biochem
, vol.69
, pp. 751-793
-
-
Hilvert, D.1
-
67
-
-
0029590066
-
Efficient aldolase catalytic antibodies that use the enamine mechanism of natural enzymes
-
Wagner J, Lerner RA, Barbas CF. Efficient aldolase catalytic antibodies that use the enamine mechanism of natural enzymes. Science 1995;270:1797-800
-
(1995)
Science
, vol.270
, pp. 1797-1800
-
-
Wagner, J.1
Lerner, R.A.2
Barbas, C.F.3
-
68
-
-
0031037466
-
Chemical selection for catalysis in combinatorial antibody libraries
-
Janda KD, Lo L-C, Lo C-HL, et al. Chemical selection for catalysis in combinatorial antibody libraries. Science 1997;275:945-8
-
(1997)
Science
, vol.275
, pp. 945-948
-
-
Janda, K.D.1
Lo, L.-C.2
Lo, C.-H.L.3
-
69
-
-
0038023153
-
Turnover-based in vitro selection and evolution of biocatalysts from a fully synthetic antibody library
-
Cesaro-Tadic S, Lagos D, Honegger A, et al. Turnover-based in vitro selection and evolution of biocatalysts from a fully synthetic antibody library. Nat Biotechnol 2003;21:679-85
-
(2003)
Nat Biotechnol
, vol.21
, pp. 679-685
-
-
Cesaro-Tadic, S.1
Lagos, D.2
Honegger, A.3
-
70
-
-
34547958191
-
Selection and evolution of enzymes from a partially randomized non-catalytic scaffold
-
Seelig B, Szostak JW. Selection and evolution of enzymes from a partially randomized non-catalytic scaffold. Nature 2007;448:828-33
-
(2007)
Nature
, vol.448
, pp. 828-833
-
-
Seelig, B.1
Szostak, J.W.2
-
71
-
-
0035810165
-
Functional proteins from a random-sequence library
-
Keefe AD, Szostak JW Functional proteins from a random-sequence library. Nature 2001;410:715-8
-
(2001)
Nature
, vol.410
, pp. 715-718
-
-
Keefe, A.D.1
Szostak, J.W.2
-
72
-
-
3042693137
-
Evolutionary optimization of a nonbiological ATP binding protein for improved folding stability
-
Chaput JC, Szostak JW. Evolutionary optimization of a nonbiological ATP binding protein for improved folding stability. Chem Biol 2004; 11:865-74
-
(2004)
Chem Biol
, vol.11
, pp. 865-874
-
-
Chaput, J.C.1
Szostak, J.W.2
-
73
-
-
34447261675
-
Structure and evolutionary analysis of a non-biological ATP-binding protein
-
Mansy SS, Zhang J, kummerle R, et al. Structure and evolutionary analysis of a non-biological ATP-binding protein. J Mol Biol 2007;371:501-13
-
(2007)
J Mol Biol
, vol.371
, pp. 501-513
-
-
Mansy, S.S.1
Zhang, J.2
kummerle, R.3
-
74
-
-
1842577640
-
A novel ADP- and zinc-binding fold from function-directed in vitro evolution
-
Lo Surdo P, Walsh MA, Sollazzo M. A novel ADP- and zinc-binding fold from function-directed in vitro evolution. Nat Struct Mol Biol 2004; 11:382-3
-
(2004)
Nat Struct Mol Biol
, vol.11
, pp. 382-383
-
-
Lo Surdo, P.1
Walsh, M.A.2
Sollazzo, M.3
-
75
-
-
0038752617
-
Computational design of receptor and sensor proteins with novel functions
-
Looger LL, Dwyer MA, Smith JJ, Hellinga HW Computational design of receptor and sensor proteins with novel functions. Nature 2003;423:185-90
-
(2003)
Nature
, vol.423
, pp. 185-190
-
-
Looger, L.L.1
Dwyer, M.A.2
Smith, J.J.3
Hellinga, H.W.4
-
76
-
-
0035807809
-
Enzyme-like proteins by computational design
-
Bolon DN, Mayo SL. Enzyme-like proteins by computational design. Proc Natl Acad Sci USA 2001;98:14274-9
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 14274-14279
-
-
Bolon, D.N.1
Mayo, S.L.2
-
77
-
-
40449116114
-
De novo computational design of reto-aldol enzymes
-
Jiang L, Althoff EA, Clemente FR, et al. De novo computational design of reto-aldol enzymes. Science 2008;319:1387-91
-
(2008)
Science
, vol.319
, pp. 1387-1391
-
-
Jiang, L.1
Althoff, E.A.2
Clemente, F.R.3
-
78
-
-
33745278855
-
Computational redesign of endonuclease DNA binding and cleavage specificity
-
Ashworth J, HavranekJJ, Duarte CM, et al. Computational redesign of endonuclease DNA binding and cleavage specificity. Nature 2006;441:656-9
-
(2006)
Nature
, vol.441
, pp. 656-659
-
-
Ashworth, J.1
Havranek, J.J.2
Duarte, C.M.3
-
79
-
-
43449098518
-
Kemp elimination catalysts by computational enzyme design
-
Rothlisberger D, Khersonsky O, Wollacott AM, et al. Kemp elimination catalysts by computational enzyme design. Nature 2008;453:190-5
-
(2008)
Nature
, vol.453
, pp. 190-195
-
-
Rothlisberger, D.1
Khersonsky, O.2
Wollacott, A.M.3
|