Reduced hepatic expression of adipose tissue triglyceride lipase and CGI-58 may contribute to the development of non-alcoholic fatty liver disease in patients with insulin resistance

Scandinavian Journal of Gastroenterology

Volumn 43, Issue 8, 2008, Pages 1018-1019

  Kato, Masaki ^a   Higuchi, Nobito ^a   Enjoji, Munechika ^a  

^a KYUSHU UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

FAT DROPLET; TRIACYLGLYCEROL LIPASE;

ADIPOSE TISSUE; CGI 58 GENE; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE COURSE; GENE EXPRESSION; HUMAN; HUMAN TISSUE; INSULIN RESISTANCE; LETTER; LIPOLYSIS; LIVER BIOPSY; NONALCOHOLIC FATTY LIVER; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATOR GENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ADIPOSE TISSUE; BIOLOGICAL MARKERS; DISEASE PROGRESSION; FATTY LIVER; HUMANS; INSULIN RESISTANCE; LIPASE;

EID: 47949122678     PISSN: 00365521     EISSN: 15027708     Source Type: Journal    
DOI: 10.1080/00365520802008140     Document Type: Letter

References (4)

1. Carmen GY, Victor SM. Signalling mechanisms regulating lipolysis. Cell Signal 2006;18:401-8.
2. Lefevre C, Jobard F, Caux F, Bouadjar B, Karaduman A, Heilig R, et al. Mutations in CGI-58, the gene encoding a new protein of the esterase/lipase/ thioesterase subfamily, in Chanarin-Dorfman syndrome. Am J Hum Genet 2001;69:1002-12.
3. Jocken JW, Langin D, Smit E, Saris WH, Valle C, Hul GB, et al. Adipose triglyceride lipase and hormone-sensitive lipase protein expression is decreased in the obese insulin-resistant state. J Clin Endocrinol Metab 2007;92:2292-9.
4. Kohjima M, Enjoji M, Higuchi N, Kato M, Kotoh K, Yoshimoto T, et al. Re-evaluation of fatty acid metabolism-related gene expression in nonalcoholic fatty liver disease. Int J Mol Med 2007;20:351-8.