Effects of vestibular training on motion sickness, nystagmus, and subjective vertical

Journal of Vestibular Research: Equilibrium and Orientation

Volumn 17, Issue 5-6, 2007, Pages 227-237

  Clément, Gilles ^a   Deguine, Olivier ^b   Bourg, Mathieu ^a   Traon, Anne Pavy Le ^c  

^a Brain and Cognition Research Center in Toulouse   (France)

^b CHU PURPAN   (France)

^c CHU RANGUEIL   (France)

Author keywords

Acetylleucine; Adaptation; Habituation; Motion sickness; Vestibulo ocular reflex

Indexed keywords

ANTIVERTIGO AGENT; N ACETYLLEUCINE; PLACEBO;

ABSENCE OF SIDE EFFECTS; ADULT; CLINICAL ARTICLE; CONFERENCE PAPER; CONTROL GROUP; CONTROLLED STUDY; HABITUATION; HUMAN; LETHARGY; MALE; MOTION SICKNESS; OPTOKINETIC NYSTAGMUS; PRIORITY JOURNAL; PROVOCATION; SPATIAL ORIENTATION; TRAINING; VERTIGO; VESTIBULOOCULAR REFLEX;

ADULT; HABITUATION, PSYCHOPHYSIOLOGIC; HUMANS; LEUCINE; MALE; MOTION SICKNESS; NYSTAGMUS, PHYSIOLOGIC; POSTURE; ROTATION; VESTIBULE, LABYRINTH;

EID: 47949113354     PISSN: 09574271     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (45)

1. W. Bles, Coriolis effects and motion sickness modeling, Brain Res Bull 47 (1988), 543-549.
2. W. Bles, J.E. Bos, B. de Graaf, E. Groen and A.H. Wertheim, Motion sickness: only one provocative conflict? Brain Res Bull 47 (1998), 481-487.
3. A. Bohmer and J. Rickenmann, The subjective visual vertical as a clinical parameter of vestibular function in peripheral vestibular diseases, J Vestib Res 5 (1995), 35-45.
4. T. Brandt, M. Dieterich and A. Daneck, Vestibular cortex lesions affect the perception of verticality, Ann Neurol 35 (1994), 403-412.
5. J. Célice, O. Leau, R. Ducrot and G. Duchesnay, Essai de traitement des vertiges labyrinthiques par l'acetyl-DL-leucine, Thérapie 13 ((1958), 620-624.
6. G. Clément, J.H. Courjon, M. Jeannerod and R. Schmid, Unidirectional habituation of vestibulo-ocular responses by repeated rotational or optokinetic stimulations in the cat, Exp Brain Res 42 (1981), 34-42.
7. G. Clément and C.E. Lathan, Effects of static tilt about roll axis on horizontal and vertical optokinetic nystagmus and optokinetic afternystagmus in humans, Exp Brain Res 84 (1991), 335-341.
8. G. Clément, O. Deguine, M. Parant, M.C. Costes-Salon, P. Vasseur-Clausen and A. Pavy-LeTraon, Effects of cosmonaut vestibular training on vestibular function prior to space flight, Eur J Appl Physiol 85 (2001), 539-545
9. H. Cohen, B. Cohen, T. Raphan and W. Waespe, Habituation and adaptation of the vestibulo-ocular reflex: a model of differential control by the vestibulo-cerebellum, Exp Brain Res 90 (1992), 526-538.
10. W.E. Collins, Habituation of vestibular responses: An overview, in: Fifth Symposium on the Role of the Vestibular Organs in Space Exploration. NASA SP-314, Washington DC, 1973, 157-193.
11. M. Dai, A. Klein, B. Cohen and T. Raphan, Model-based study of the human cupular time constant, J Vestib Res 9 (1999), 293-301.
12. M. Dai, M. Kunin, T. Raphan and B. Cohen, The relation of motion sickness to the spatial - temporal properties of velocity storage, Exp Brain Res 151 (2003), 173-189.
13. J.R. Davis, J.M. Vanderploeg, P.A. Santy, R.T. Jenings and D.F. Stewart, Space motion sickness during 24 flights of the space shuttle, Aviat Space Environ Med 59 (1988), 1185-1189.
14. M. Dieterich and T. Brandt, Ocular torsion and tilt of subjective visual vertical are sensitive brainstem signs, Ann Neurol 33 (1993), 292-299.
15. A. Graybiel, C.D. Wood, E.F. Miller and D.B. Cramer, Diagnostic criteria for grading the severity of acute motion sickness, Aerosp Med 39 (1968), 453-455.
16. A. Graybiel and J.C. Knepton, Direction-specific adaptation effects acquired in a slow rotating room, Aerospace Med 43 (1972), 1179-1189.
17. E. Groen, J. Bos, B. DeGraaf and W. Bles, Otolith signal processing and motion sickness, Ann NY Acad Sci 871 (1999), 406-409.
18. M. Gizzi, T. Raphan, S. Rudolph and B. Cohen, Orientation of human optokinetic nystagmus to gravity: a model-based approach, Exp Brain Res 99 (1994), 347-360.
19. F.E. Guedry, Habituation to complex vestibular stimulation in man: transfer and retention of effects from twelve days of rotation at 10 rpm, Percept Mot Skills 21 (1965), 459-481.
20. F.E. Guedry, Psychophysics of vestibular sensation, in: Handbook of Sensory Physiology, (Vol. 6), Springer, Berlin, Heidelberg, New York, 1974, pp. 3-154.
21. F.E. Guedry and A.J. Benson, Coriolis cross-coupling effects: disorienting and nauseogenic or not? Aviat Space Environ Med 49 (1978), 29-35.
22. F.E. Guedry, A. Graybiel and W.E. Collins, Reduction of nystagmus and disorientation in human subjects, Aerospace Med 33 (1962), 1356-1360.
23. F.E. Guedry, W.E. Collins and A. Graybiel, Vestibular habituation during repetitive complex stimulation: a study of transfer effects, J Appl Physiol 19 (1964), 1005-1015.
24. F.E. Guedry and A.J. Benson, Coriolis crosscoupling effects: disorienting and nauseogenic or not? Aviat Space Environ Med 49 (1978), 29-35.
25. F.E. Guedry, A.R. Rupert and M.F. Reschke, Motion sickness and development of synergy within the spatial orientation system. A hypothetical unifying concept, Brain Res Bull 47 (1998), 475-480.
26. G.M. Halmagyi and I.S. Curthoys, Clinical testing of otolith function, Ann NY Acad Sci 871 (1999), 195-204.
27. I.P. Howard and W.B. Templeton, Human Spatial Orientation, Wiley, New York, 1966.
28. J.R. Lackner and A. Graybiel, The effective intensity of Coriolis, crosscoupling stimulation is gravitoinertial force dependent: implications for space motion sickness, Aviat Space Environ Med 57 (1986), 229-235.
29. J.R. Lackner and A. Graybiel, Use of promethazine to hasten adaptation to provocative motion, J Clin Pharmacol 34 (1994), 644-648.
30. M. Lacour, Influence d'un traitement pharmaceutique à l'acétyl-DL-leucine dans la compensation des deficits vestibulaires chez le chat. Etude neurophysiologique. Pierre Fabre Médicaments, Castres, France, 1995.
31. A. Léger, A. Schnerb, D. Lejeune, J.C. Glisse and H. Vieillefond, Effet de l'acétyl-DL-leucine sur les caractéristiques du réflexe vestibulo-oculaire per et post rotatoire, Méd Armées 13 (1985), 269-274.
32. C.M. Oman, A heuristic mathematical model for the dynamics of sensory conflict and motion sickness, Acta Otolaryngol (Suppl) 392 (1982), 4-44.
33. T. Raphan, V. Matsuo and B. Cohen, Velocity storage in the vestibulo-ocular reflex arc (VOR), Exp Brain Res 35 (1979), 229-248.
34. T. Raphan, M. Dai and B. Cohen, Spatial orientation of the vestibular system, Ann NY Acad Sci 656 (1992), 140-157.
35. O. Rascol, T.C. Hain, C. Brefel et al., Antivertigo medications and drug-induced vertigo. A pharmacological review, Drugs 50 (1995), 777-791.
36. J.T. Reason and J.J. Brand, Motion Sickness, Academic Press, London, 1975.
37. G.T. Singleton, Relationships of the cerebellar nodulus to vestibular function: a study of the effects of nodulectomy on habituation, Laryngoscope 77 (1967), 1579-1620.
38. H. Thai-Van, M.J. Bounaix and B. Fraysse, Menière's disease: Pathophysiology and treatment, Drugs 61 (2001), 1089-1102.
39. M. Triesman, Motion sickness: An evolutionary hypothesis, Science 197 (1977), 493-495.
40. D. Vibert, R. Hausler and A.B. Safran, Subjective visual vertical in peripheral unilateral vestibular diseases, J Vestib Res 9 (1999), 145-152.
41. D. Vibert and R. Hausler, Long-term evolution of subjective visual vertical after vestibular neurectomy and labyrinthectomy, Acta Otolaryngol 120 (2000), 620-622.
42. N. Vibert and P.P. Vidal, In vitro effects of acetyl-DL-leucine (Tanganilè) on central vestibular neurons and vestibulo-ocular networks of the guinea-pig, Eur J Neurosci 13 (2001), 735-748.
43. J. Wetzig, K. Hofstetter-Degen and R. von Baumgarten, Responses to eccentric rotation in two space-bound subjects, Clin Investig 71 (1993), 757-760.
44. C.D. Wood and A. Graybiel, Evaluation of sixteen anti-motion sickness drugs under controlled laboratory conditions, Aerosp Med 39 (1968), 1341-1344.
45. B.J. Yates, A.D. Miller and J.D. Lucot, Physiological basis and pharmacology of motion sickness: an update, Brain Res Bull 47 (1998), 395-406.