Design and kinetic analysis of hammerhead ribozyme and DNAzyme that specifically cleave TEL-AML1 chimeric mRNA

Biochemical and Biophysical Research Communications

Volumn 374, Issue 1, 2008, Pages 169-174

  Choi, Woo Hyung ^a   Choi, Bo Ra ^a   Kim, Jae Hyun ^b   Yeo, Woon Seok ^a   Oh, Sangtaek ^c   Kim, Dong Eun ^a  

^a Konkuk University   (South Korea)

^b Nambu Blood Laboratory   (South Korea)

^c Inje University   (South Korea)

Author keywords

Acute lymphoblastic leukemia; Hammerhead ribozyme; Oligodeoxyribozyme; TEL AML1 fusion

Indexed keywords

DEOXYRIBOZYME; DNAZYME; HAMMERHEAD RIBOZYME; HYBRID PROTEIN; MESSENGER RNA; TEL AML1 PROTEIN; TRANSCRIPTION FACTOR ETV6;

ACUTE LYMPHOBLASTIC LEUKEMIA; ARTICLE; CATALYSIS; CONFORMATIONAL TRANSITION; ENZYME KINETICS; ENZYME SPECIFICITY; ENZYMOLOGY; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RNA CLEAVAGE;

CATALYSIS; CELL LINE, TUMOR; CORE BINDING FACTOR ALPHA 2 SUBUNIT; DNA, CATALYTIC; GENE TRANSFER TECHNIQUES; HUMANS; KINETICS; OLIGONUCLEOTIDES; ONCOGENE PROTEINS, FUSION; RNA, CATALYTIC; RNA, MESSENGER;

EID: 47949106834     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2008.07.008     Document Type: Article

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