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Volumn 87, Issue 3, 2008, Pages 359-368

Healthcare sustainability and the challenges of innovation to biopharmaceuticals in Canada

Author keywords

Biotechnology; Fairness; Priority setting; Resource allocation

Indexed keywords

ARTICLE; BIOTECHNOLOGY; CANADA; DRUG INDUSTRY; GOVERNMENT REGULATION; HEALTH CARE ACCESS; HEALTH CARE POLICY; HEALTH CARE SYSTEM;

EID: 47849099279     PISSN: 01688510     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.healthpol.2008.02.004     Document Type: Article
Times cited : (24)

References (59)
  • 1
    • 47849100451 scopus 로고    scopus 로고
    • Society for Mucopolysaccharide Diseases [cited June 8, 2006]; available from: http://www.mpssociety.co.uk/pages/maroteaux.htm.
    • Society for Mucopolysaccharide Diseases [cited June 8, 2006]; available from: http://www.mpssociety.co.uk/pages/maroteaux.htm.
  • 2
    • 47849108271 scopus 로고    scopus 로고
    • Priest L. A Family's Choice to Relocate or Watch their Toddler Suffer, April 29; 2006 [cited May 10, 2006]; available from: www.globeandmail.com.
    • Priest L. A Family's Choice to Relocate or Watch their Toddler Suffer, April 29; 2006 [cited May 10, 2006]; available from: www.globeandmail.com.
  • 3
    • 47849092587 scopus 로고    scopus 로고
    • Naglazyme [cited June 11, 2006]; available from: http://www.naglazyme.com/.
    • Naglazyme [cited June 11, 2006]; available from: http://www.naglazyme.com/.
  • 4
    • 47849131950 scopus 로고    scopus 로고
    • Priest L. Boy to get costly drug [cited August 15, 2006]; available from: http://www.theglobeandmail.com/servlet/ArticleNews/freeheadlines/LAC/20060715/BOY15/health/Health.
    • Priest L. Boy to get costly drug [cited August 15, 2006]; available from: http://www.theglobeandmail.com/servlet/ArticleNews/freeheadlines/LAC/20060715/BOY15/health/Health.
  • 5
    • 47849126652 scopus 로고    scopus 로고
    • Isaac Foundation [cited November 15, 2007]; available from: www.theisaacfoundation.com/isaac.doc.
    • Isaac Foundation [cited November 15, 2007]; available from: www.theisaacfoundation.com/isaac.doc.
  • 6
    • 31544452135 scopus 로고    scopus 로고
    • Is the current approach to reviewing new drugs condemning the victims of rare diseases to death? A call for a national orphan drug review policy
    • Clarke J.T.R. Is the current approach to reviewing new drugs condemning the victims of rare diseases to death? A call for a national orphan drug review policy. CMAJ 174 2 (2006)
    • (2006) CMAJ , vol.174 , Issue.2
    • Clarke, J.T.R.1
  • 7
    • 33846942298 scopus 로고    scopus 로고
    • Our moral obligations in caring for patients with orphan cancers
    • Fernandez C.V. Our moral obligations in caring for patients with orphan cancers. CMAJ 176 3 (2007)
    • (2007) CMAJ , vol.176 , Issue.3
    • Fernandez, C.V.1
  • 8
    • 47849112361 scopus 로고    scopus 로고
    • A framework for biotechnology statistics. OECD; 2005 [cited July 18, 2006]; available from: http://www.oecd.org/dataoecd/5/48/34935605.pdf.
    • A framework for biotechnology statistics. OECD; 2005 [cited July 18, 2006]; available from: http://www.oecd.org/dataoecd/5/48/34935605.pdf.
  • 9
    • 47849129230 scopus 로고    scopus 로고
    • Innovation in Pharmaceutical Biotechnology: Comparing International Systems at the Sectoral Level, OECD, Editor; 2006.
    • Innovation in Pharmaceutical Biotechnology: Comparing International Systems at the Sectoral Level, OECD, Editor; 2006.
  • 10
    • 34547747293 scopus 로고    scopus 로고
    • Boston Harvard Business School Press
    • Pisano G.P. Science business (2006), Boston Harvard Business School Press
    • (2006) Science business
    • Pisano, G.P.1
  • 11
    • 47849123764 scopus 로고    scopus 로고
    • Drug expenditure in Canada 1985-2006; 2006. Accessed on November 8, 2007 from Canadian Institute for Health Information 2006 [cited November 8, 2007]; available from: www.secure.cihi.ca-Drug_Expenditure_in_Canada_2007_e.pdf.
    • Drug expenditure in Canada 1985-2006; 2006. Accessed on November 8, 2007 from Canadian Institute for Health Information 2006 [cited November 8, 2007]; available from: www.secure.cihi.ca-Drug_Expenditure_in_Canada_2007_e.pdf.
  • 12
    • 47849094638 scopus 로고    scopus 로고
    • Projecting OECD health and long-term care expenditures: what are the main drivers? Economics Department Working Papers No. 477 2006 [cited July 24, 2006]; available from: http://www.oecd.org/dataoecd/57/7/36085940.pdf.
    • Projecting OECD health and long-term care expenditures: what are the main drivers? Economics Department Working Papers No. 477 2006 [cited July 24, 2006]; available from: http://www.oecd.org/dataoecd/57/7/36085940.pdf.
  • 13
    • 0026755327 scopus 로고
    • Translating technology assessment into policy: conceptual issues and tough choices
    • Deber R. Translating technology assessment into policy: conceptual issues and tough choices. International Journal of Technology Assessment in Health Care 8 1 (1992) 131-137
    • (1992) International Journal of Technology Assessment in Health Care , vol.8 , Issue.1 , pp. 131-137
    • Deber, R.1
  • 14
    • 47849111289 scopus 로고    scopus 로고
    • Romanow RJ. Shape of the Future of Health Care Interim Report, G.o. Canada, Editor; 2002. p. 1.
    • Romanow RJ. Shape of the Future of Health Care Interim Report, G.o. Canada, Editor; 2002. p. 1.
  • 15
    • 47849097750 scopus 로고    scopus 로고
    • Innovation in the pharmaceutical sector: a study undertaken for the European commission. 2004 [cited November 12, 2007]; available from: ec.europa.eu/enterprise/pharmaceuticals/pharmacos/docs/doc2004/nov/eu_pharma_innovation_25-11-04.pdf.
    • Innovation in the pharmaceutical sector: a study undertaken for the European commission. 2004 [cited November 12, 2007]; available from: ec.europa.eu/enterprise/pharmaceuticals/pharmacos/docs/doc2004/nov/eu_pharma_innovation_25-11-04.pdf.
  • 16
    • 47849132492 scopus 로고    scopus 로고
    • A Vision for a Healthier Tomorrow. Financial Post Business Joint Venture Supplement; May 2007. p. 1-8.
    • A Vision for a Healthier Tomorrow. Financial Post Business Joint Venture Supplement; May 2007. p. 1-8.
  • 17
    • 47849132759 scopus 로고    scopus 로고
    • OECD [cited July 27, 2006]; available from: http://www.oecd.org/document/0,2340,en_2649_34487_25998799_1_1_1_1,00.html.
    • OECD [cited July 27, 2006]; available from: http://www.oecd.org/document/0,2340,en_2649_34487_25998799_1_1_1_1,00.html.
  • 18
    • 34548544836 scopus 로고    scopus 로고
    • The Role of the Health System in Health Biotechnology in Developing Countries
    • Thorsteinsdóttir H. The Role of the Health System in Health Biotechnology in Developing Countries. Technology Analysis & Strategic Management 19 5 (2007) 659-675
    • (2007) Technology Analysis & Strategic Management , vol.19 , Issue.5 , pp. 659-675
    • Thorsteinsdóttir, H.1
  • 19
    • 47849104727 scopus 로고    scopus 로고
    • Luger M, Maynard N, Christie L. European Trend Chart on Innovation. Annual Innovation Policy Trends Report for United States, Canada, Mexico and Brazil. E.C.E. Directorate-General, Editor; 2005.
    • Luger M, Maynard N, Christie L. European Trend Chart on Innovation. Annual Innovation Policy Trends Report for United States, Canada, Mexico and Brazil. E.C.E. Directorate-General, Editor; 2005.
  • 20
    • 47849086628 scopus 로고    scopus 로고
    • CIHR [cited October 26, 2006]; available from: http://www.cihr-irsc.gc.ca/e/30240.html#slide1_e.
    • CIHR [cited October 26, 2006]; available from: http://www.cihr-irsc.gc.ca/e/30240.html#slide1_e.
  • 21
    • 47849088464 scopus 로고    scopus 로고
    • Industry Canada. Achieving excellence: investing in people, knowledge and opportunity Canada's innovation strategy 2001 [cited 2006 February 7]; Available from: http://www.innovationstrategy.gc.ca/gol/innovation/site.nsf/vDownload/Page_PDF/$file/Achieving.pdf.
    • Industry Canada. Achieving excellence: investing in people, knowledge and opportunity Canada's innovation strategy 2001 [cited 2006 February 7]; Available from: http://www.innovationstrategy.gc.ca/gol/innovation/site.nsf/vDownload/Page_PDF/$file/Achieving.pdf.
  • 22
    • 47849120470 scopus 로고    scopus 로고
    • Innovation in Canada. Submission - Federal Department Report - Innovation and Health [cited February 21, 2006]; available from: http://www.innovationstrategy.gc.ca/gol/innovation/site.nsf/en/in02330.htm.
    • Innovation in Canada. Submission - Federal Department Report - Innovation and Health [cited February 21, 2006]; available from: http://www.innovationstrategy.gc.ca/gol/innovation/site.nsf/en/in02330.htm.
  • 23
    • 47849117405 scopus 로고    scopus 로고
    • Economic Importance of Biotechnology Industry to Canada. Accessed on February 7, 2006 from [cited February 7, 2006]; available from: http://www.biotech.ca/EN/baMay0801.html.
    • Economic Importance of Biotechnology Industry to Canada. Accessed on February 7, 2006 from [cited February 7, 2006]; available from: http://www.biotech.ca/EN/baMay0801.html.
  • 24
    • 47849084564 scopus 로고    scopus 로고
    • OECD Science, Technology and Industry Outlook 2004 Country Response to Policy Questionnaire [cited February 7, 2006]; available from: www.oecd.org/document/60/0,2340,en_2649_33703_33995839_1_1_1_1,00.html.
    • OECD Science, Technology and Industry Outlook 2004 Country Response to Policy Questionnaire [cited February 7, 2006]; available from: www.oecd.org/document/60/0,2340,en_2649_33703_33995839_1_1_1_1,00.html.
  • 25
    • 47849103015 scopus 로고    scopus 로고
    • Industry Canada [cited February 7, 2006]; available from: http://www.biostrategy.gc.ca/english/View.asp?pmiid=520&x=535.
    • Industry Canada [cited February 7, 2006]; available from: http://www.biostrategy.gc.ca/english/View.asp?pmiid=520&x=535.
  • 27
    • 47849100449 scopus 로고    scopus 로고
    • Canada's Biotechnology Strategy [cited May 10, 2007]; available from: http://hc-sc.gc/sr-sr/biotech/role/strateg/index_e.html.
    • Canada's Biotechnology Strategy [cited May 10, 2007]; available from: http://hc-sc.gc/sr-sr/biotech/role/strateg/index_e.html.
  • 28
    • 47849095172 scopus 로고    scopus 로고
    • Canadian Biotechnology Advisory Committee [cited May 10, 2007]; available from: http://www.cbac-cccb.ca/epic/site/cbac-cccb.nsf/en/h_ah00002e.html.
    • Canadian Biotechnology Advisory Committee [cited May 10, 2007]; available from: http://www.cbac-cccb.ca/epic/site/cbac-cccb.nsf/en/h_ah00002e.html.
  • 29
    • 47849091228 scopus 로고    scopus 로고
    • Canadian Biotechnology Strategy [cited February 7, 2006]; available from: http://www.tbs-sct.gc.ca/rma/eppi-ibdrp/hrdb-rhbd/cbs-scb/description_e.asp#g3.
    • Canadian Biotechnology Strategy [cited February 7, 2006]; available from: http://www.tbs-sct.gc.ca/rma/eppi-ibdrp/hrdb-rhbd/cbs-scb/description_e.asp#g3.
  • 30
    • 47849112643 scopus 로고    scopus 로고
    • Backing Australia's ability [cited July 18, 2006]; available from: http://backingaus.innovation.gov.au/info_booklet/exec_summary.htm.
    • Backing Australia's ability [cited July 18, 2006]; available from: http://backingaus.innovation.gov.au/info_booklet/exec_summary.htm.
  • 31
    • 47849109024 scopus 로고    scopus 로고
    • Competing in the global economy: the innovation challenge D.I. Report, Editor; 2003.
    • Competing in the global economy: the innovation challenge D.I. Report, Editor; 2003.
  • 32
    • 47849096175 scopus 로고    scopus 로고
    • Martin R, Milway J. Assessing the Strength of the Toronto Biopharmaceutical Cluster. 2004 [cited January 31, 2007]; available from: http://www.competeprosper.ca/clusters/biopharmaCluster.pdf.
    • Martin R, Milway J. Assessing the Strength of the Toronto Biopharmaceutical Cluster. 2004 [cited January 31, 2007]; available from: http://www.competeprosper.ca/clusters/biopharmaCluster.pdf.
  • 33
    • 47849089734 scopus 로고    scopus 로고
    • Romanow RJ. Building on Values: The Future of Health Care in Canada T.C.o.t.f.o.h.i. Canada, Editor; 2002, Government of Canada.
    • Romanow RJ. Building on Values: The Future of Health Care in Canada T.C.o.t.f.o.h.i. Canada, Editor; 2002, Government of Canada.
  • 34
    • 47849093345 scopus 로고    scopus 로고
    • Zelmer J, et al. Health Care in Canada 2007, C.I.f.H. Information, Editor. Ottawa: Canadian Institute for Health Information; 2007.
    • Zelmer J, et al. Health Care in Canada 2007, C.I.f.H. Information, Editor. Ottawa: Canadian Institute for Health Information; 2007.
  • 35
    • 33749333428 scopus 로고    scopus 로고
    • Prices and availability of biopharmaceuticals: an internal comparison
    • Danzon P.M., and Furukawa M. Prices and availability of biopharmaceuticals: an internal comparison. Health Affairs 25 (2006) 1353-1362
    • (2006) Health Affairs , vol.25 , pp. 1353-1362
    • Danzon, P.M.1    Furukawa, M.2
  • 36
    • 47849131133 scopus 로고    scopus 로고
    • Lorinc J. How much are drugs worth? University of Toronto Magazine. Toronto; 2006. p. 28-29.
    • Lorinc J. How much are drugs worth? University of Toronto Magazine. Toronto; 2006. p. 28-29.
  • 37
    • 47849111580 scopus 로고    scopus 로고
    • Drug Expenditure in Canada 1985-2003, CIHI, Editor. Ottawa: Canadian Institute for Health Information; 2004. p. 91-93.
    • Drug Expenditure in Canada 1985-2003, CIHI, Editor. Ottawa: Canadian Institute for Health Information; 2004. p. 91-93.
  • 38
    • 47849093588 scopus 로고    scopus 로고
    • Sykes RB. New Medicines: The Practice of Medicine and Public Policy. London: Stationery Office; 2000.
    • Sykes RB. New Medicines: The Practice of Medicine and Public Policy. London: Stationery Office; 2000.
  • 39
    • 47849091484 scopus 로고    scopus 로고
    • Common Drug Review Process [cited October 11, 2007]; available from: http://www.cadth.ca/index.php/en/cdr/process.
    • Common Drug Review Process [cited October 11, 2007]; available from: http://www.cadth.ca/index.php/en/cdr/process.
  • 40
    • 47849122008 scopus 로고    scopus 로고
    • CEDAC [cited November 17, 2007]; available from: http://www.cadth.ca/index.php/en/cdr/committees/cedac.
    • CEDAC [cited November 17, 2007]; available from: http://www.cadth.ca/index.php/en/cdr/committees/cedac.
  • 41
    • 47849119788 scopus 로고    scopus 로고
    • CEDAC. CDR drug database listing on agalsidase beta; 2005 [cited November 17, 2007]; available from: http://www.cadth.ca/index.php/en/cdr/search/?&status=all&keywords=agalsidase%20beta.
    • CEDAC. CDR drug database listing on agalsidase beta; 2005 [cited November 17, 2007]; available from: http://www.cadth.ca/index.php/en/cdr/search/?&status=all&keywords=agalsidase%20beta.
  • 42
    • 47849086378 scopus 로고    scopus 로고
    • Koning E. Patient's Perspective on Access to Innovative Therapies for Rare Disorders [cited November 27, 2007]; available from: http://www.cord.ca/index.php/site/content/search?SearchText=koning.
    • Koning E. Patient's Perspective on Access to Innovative Therapies for Rare Disorders [cited November 27, 2007]; available from: http://www.cord.ca/index.php/site/content/search?SearchText=koning.
  • 43
    • 47849126893 scopus 로고    scopus 로고
    • Special Access Programme; 2005 [cited November 15, 2007]; available from: http://www.hc-sc.gc.ca/dhp-mps/acces/drugs-drogues/sapfs_pasfd_2002_e.html.
    • Special Access Programme; 2005 [cited November 15, 2007]; available from: http://www.hc-sc.gc.ca/dhp-mps/acces/drugs-drogues/sapfs_pasfd_2002_e.html.
  • 44
    • 47849100448 scopus 로고    scopus 로고
    • Drug Product Search; 2007 [cited November 15, 2007]; available from: http://cpe0013211b4c6d-cm0014e88ee7a4.cpe.net.cable.rogers.com/dpdonline/startup.do.
    • Drug Product Search; 2007 [cited November 15, 2007]; available from: http://cpe0013211b4c6d-cm0014e88ee7a4.cpe.net.cable.rogers.com/dpdonline/startup.do.
  • 45
    • 47849111876 scopus 로고    scopus 로고
    • Biotechnology, Innovation, and Health [cited December 5, 2005]; available from: http://www.oecd.org/document/10/0,2340,en_2649_201185_33790794_1_1_1_1,00.html.
    • Biotechnology, Innovation, and Health [cited December 5, 2005]; available from: http://www.oecd.org/document/10/0,2340,en_2649_201185_33790794_1_1_1_1,00.html.
  • 46
    • 47849129498 scopus 로고    scopus 로고
    • Toward a Canadian Action Agenda for Biotechnology, C.B.A. Committee, Editor; 2006. p. 57.
    • Toward a Canadian Action Agenda for Biotechnology, C.B.A. Committee, Editor; 2006. p. 57.
  • 48
    • 0037225828 scopus 로고    scopus 로고
    • How Ontario's formulary committee makes recommendations
    • PausJenssen A., Singer P.A., and Detsky A.S. How Ontario's formulary committee makes recommendations. Pharmacoeconomics 21 (2003) 285-294
    • (2003) Pharmacoeconomics , vol.21 , pp. 285-294
    • PausJenssen, A.1    Singer, P.A.2    Detsky, A.S.3
  • 49
    • 0034822074 scopus 로고    scopus 로고
    • Managing public payment for high cost, high-benefit therapy for Gaucher's disease in Ontario
    • Clarke J.T.R., Amato D., and Deber R.B. Managing public payment for high cost, high-benefit therapy for Gaucher's disease in Ontario. CMAJ 165 5 (2001) 595
    • (2001) CMAJ , vol.165 , Issue.5 , pp. 595
    • Clarke, J.T.R.1    Amato, D.2    Deber, R.B.3
  • 50
    • 0030946526 scopus 로고    scopus 로고
    • Regulating biotechnology: a rational-political model of policy development
    • Wiktorowicz M., and Deber R. Regulating biotechnology: a rational-political model of policy development. Health Policy 40 (1997) 116
    • (1997) Health Policy , vol.40 , pp. 116
    • Wiktorowicz, M.1    Deber, R.2
  • 52
    • 0037809338 scopus 로고    scopus 로고
    • Fairness, health care decision making: testing the group value model of procedural justice
    • Murphy-Berman V., Cross T., and Fondacaro M. Fairness, health care decision making: testing the group value model of procedural justice. Social Justice Research 12 2 (1999) 117-129
    • (1999) Social Justice Research , vol.12 , Issue.2 , pp. 117-129
    • Murphy-Berman, V.1    Cross, T.2    Fondacaro, M.3
  • 53
    • 18244365590 scopus 로고    scopus 로고
    • Justice in health care decision-making: patients' appraisals of health care providers and health plan representatives
    • Fondacaro M., Frogner B., and Moos R. Justice in health care decision-making: patients' appraisals of health care providers and health plan representatives. Social Justice Research 18 1 (2005) 65
    • (2005) Social Justice Research , vol.18 , Issue.1 , pp. 65
    • Fondacaro, M.1    Frogner, B.2    Moos, R.3
  • 54
    • 47849094368 scopus 로고    scopus 로고
    • Committee to Evaluate Drugs [cited November 29, 2007]; available from: http://www.health.gov.on.ca/english/providers/program/drugs/ced_recommend.html#2.
    • Committee to Evaluate Drugs [cited November 29, 2007]; available from: http://www.health.gov.on.ca/english/providers/program/drugs/ced_recommend.html#2.
  • 55
    • 47849109832 scopus 로고    scopus 로고
    • Joncheere Kd, et al. The Clinical Guideline Programme of the National Institute for Health and Clinical Excellence (NICE) A review by the World Health Organization, W.H. Organization, Editor. Denmark: World Health Organization; 2006, p. 12.
    • Joncheere Kd, et al. The Clinical Guideline Programme of the National Institute for Health and Clinical Excellence (NICE) A review by the World Health Organization, W.H. Organization, Editor. Denmark: World Health Organization; 2006, p. 12.
  • 56
    • 47849126427 scopus 로고    scopus 로고
    • NICE Special Health Authority The Clinical Guideline Programme A Review by the WHO Response to Recommendations 2007 [cited November 18, 2007]; available from: http://www.nice.org.uk/niceMedia/pdf/boardmeeting/brdjan07item2c.pdf.
    • NICE Special Health Authority The Clinical Guideline Programme A Review by the WHO Response to Recommendations 2007 [cited November 18, 2007]; available from: http://www.nice.org.uk/niceMedia/pdf/boardmeeting/brdjan07item2c.pdf.
  • 57
    • 33646377631 scopus 로고    scopus 로고
    • Centralized drug review processes: are they fair?
    • Mitton C., et al. Centralized drug review processes: are they fair?. Social Science and Medicine 63 1 (2006) 200-211
    • (2006) Social Science and Medicine , vol.63 , Issue.1 , pp. 200-211
    • Mitton, C.1
  • 58
    • 23144457414 scopus 로고    scopus 로고
    • The drive toward transparency: enhancing openness and accountability
    • Cohen S.S. The drive toward transparency: enhancing openness and accountability. Healthcare Executive 20 4 (2005) 16
    • (2005) Healthcare Executive , vol.20 , Issue.4 , pp. 16
    • Cohen, S.S.1
  • 59
    • 47849088723 scopus 로고    scopus 로고
    • Models of transparency and accountability in the biotech age
    • Anderson K., et al. Models of transparency and accountability in the biotech age. Bulletin of Science Technology and Society 26 1 (2006) 46-56
    • (2006) Bulletin of Science Technology and Society , vol.26 , Issue.1 , pp. 46-56
    • Anderson, K.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.