Up-regulation of chemokines and their receptors may contribute to pain in multiple sclerosis

Medical Hypotheses

Volumn 71, Issue 3, 2008, Pages 466-467

  Sachs, Daniela ^a   Teixeira, Antonio Lucio ^a  

^a FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE;

DISEASE COURSE; HUMAN; LETTER; MULTIPLE SCLEROSIS; NEUROPATHIC PAIN; NEUROTRANSMITTER RELEASE; PAIN ASSESSMENT; PATHOGENESIS; PREVALENCE; PRIORITY JOURNAL; SYMPTOMATOLOGY; UPREGULATION;

CHEMOKINES; HUMANS; MULTIPLE SCLEROSIS; PAIN; RECEPTORS, CHEMOKINE; UP-REGULATION;

EID: 47749149202     PISSN: 03069877     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mehy.2008.03.035     Document Type: Letter

References (5)

1. O'connor AB, Schwid SR, Herrmann DN, Markman JD, Dworkin RH. Pain associated with multiple sclerosis: systematic review and proposed classification. Pain 2007; October 8 [Epub ahead of print] PMID: 17928147.
2. Moreira M.A., Tilbery C.P., Monteiro L.P., Teixeira M.M., and Teixeira A.L. Effect of the treatment with methylprednisolone on the cerebrospinal fluid and serum levels of CCL2 and CXCL10 chemokines in patients with active multiple sclerosis. Acta Neurol Scand 114 (2006) 109-113
3. Szczuciński A., and Losy J. Chemokines and chemokine receptors in multiple sclerosis. Potential targets for new therapies. Acta Neurol Scand 115 (2007) 137-146
4. White F.A., Bhangoo S.K., and Miller R.J. Chemokines: integrators of pain and inflammation. Nat Rev Drug Discov 4 (2005) 834-844
5. White F.A., Jung H., and Miller R.J. Chemokines and the pathophysiology of neuropathic pain. Proc Natl Acad Sci USA 104 (2007) 20151-20158