Design, synthesis, conformational and membrane ion transport studies of proline-adamantane hybrid cyclic depsipeptides

Biopolymers

Volumn 89, Issue 5, 2008, Pages 471-478

  Karle, Isabella L ^a   Ranganathan, Darshan ^b   Kumar, Mittapalli Gopi ^c   Nagaraj, Ramakrishnan ^c  

^a NAVAL RESEARCH LABORATORY   (United States)

^b INDIAN INSTITUTE OF CHEMICAL TECHNOLOGY   (India)

^c CENTRE FOR CELLULAR AND MOLECULAR BIOLOGY   (India)

Author keywords

Constraints with adamantane; Crystal structure; Cyclic backbone folding; Hybrid peptide; Loops; Pseudo beta bends

Indexed keywords

ADAMANTANE; ADAMANTYL GROUPS; BUILDING BLOCKS; CONFORMATIONAL CONSTRAINT; CONSTRAINTS WITH ADAMANTANE; CRYSTAL STRUCTURE; CYCLIC BACKBONE FOLDING; CYCLIC DEPSIPEPTIDES; DEPSIPEPTIDES; HYBRID PEPTIDE; ION TRANSPORTS; LIPID MEMBRANES; LOOPS; LOW-MOLECULAR WEIGHT; MEMBRANE PERMEABILITY; PSEUDO BETA-BENDS;

ADAMANTANE; CARBON; DEPSIPEPTIDE; OXYGEN; PROLINE; SODIUM ION;

ARTICLE; CHEMICAL BOND; CHEMICAL STRUCTURE; CRYSTAL STRUCTURE; ION TRANSPORT; LIPID MEMBRANE; MEMBRANE PERMEABILITY; MEMBRANE TRANSPORT; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN SYNTHESIS; SODIUM TRANSPORT; STRUCTURE ANALYSIS; CELL MEMBRANE; CHEMISTRY; CONFORMATION; DRUG DESIGN; METABOLISM; PHYSIOLOGY; SYNTHESIS; X RAY CRYSTALLOGRAPHY;

ADAMANTANE; CELL MEMBRANE; CRYSTALLOGRAPHY, X-RAY; DEPSIPEPTIDES; DRUG DESIGN; ION TRANSPORT; MOLECULAR CONFORMATION; MOLECULAR STRUCTURE; PROLINE;

EID: 47749131992     PISSN: 00063525     EISSN: 10970282     Source Type: Journal    
DOI: 10.1002/bip.20903     Document Type: Article

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