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Volumn 18, Issue 15, 2008, Pages 4416-4419

Synthesis of some novel imidazole-based dicationic carbazolophanes as potential antibacterials

Author keywords

Antibacterial activity; Carbazolophanes; Quaternary ammonium compounds (QACs)

Indexed keywords

ANTIINFECTIVE AGENT; BENZALKONIUM CHLORIDE; CARBAZOLE DERIVATIVE; CETYLPYRIDINIUM SALT; CYCLOPHANE DERIVATIVE; IMIDAZOLE DERIVATIVE; PYRIDINE; QUATERNARY AMMONIUM DERIVATIVE; TETRACYCLINE;

EID: 47749131543     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2008.06.047     Document Type: Article
Times cited : (33)

References (35)
  • 19
    • 47749109146 scopus 로고    scopus 로고
    • note
    • 2: C, 79.62; H, 5.01; N, 10.55. Found: 79.74; H, 5.16; N, 10.68.
  • 20
    • 47749117260 scopus 로고    scopus 로고
    • note
    • 2: C, 76.71; H, 5.19; N, 12.43. Found: 76.86; H, 5.31; N, 12.56.
  • 21
    • 47749118425 scopus 로고    scopus 로고
    • note
    • 4: C, 70.93; H, 4.50; N, 6.71. Found: 70.81; H, 4.63; N, 6.84.
  • 26
    • 47749095086 scopus 로고    scopus 로고
    • note
    • 2: C, 65.96; H, 4.34; N, 9.05. Found: 65.82; H, 4.24; N, 9.18.
  • 27
    • 47749153814 scopus 로고    scopus 로고
    • note
    • 4: C, 65.66; H, 4.59; N, 7.09. Found: 65.51; H, 4.47; N, 7.21.
  • 28
    • 47749129293 scopus 로고    scopus 로고
    • note
    • 5: C, 63.17; H, 4.08; N, 8.50. Found: 63.29; H, 4.21; N, 8.63.
  • 29
    • 47749145802 scopus 로고    scopus 로고
    • note
    • 2: C, 71.18; H, 4.57; N, 6.49. Found: 71.31; H, 4.42; N, 6.62.
  • 30
    • 47749118812 scopus 로고    scopus 로고
    • note
    • 4: C, 68.75; H, 4.55; N, 7.29. Found: 68.59; H, 4.37; N, 7.16.
  • 31
    • 47749115004 scopus 로고    scopus 로고
    • note
    • 2: C, 62.33; H, 4.38; N, 10.14. Found: 62.47; H, 4.52; N, 10.28.
  • 32
    • 47749113328 scopus 로고    scopus 로고
    • note
    • 4: C, 62.24; H, 4.66; N, 7.89. Found: 62.41; H, 4.47; N, 7.72.
  • 33
    • 47749154487 scopus 로고    scopus 로고
    • note
    • 5: C, 59.47; H, 4.08; N, 9.46. Found: 59.61; H, 4.23; N, 9.57.
  • 34
    • 47749149252 scopus 로고    scopus 로고
    • note
    • 2: C, 68.65; H, 4.63; N, 7.15. Found: 68.78; H, 4.72; N, 7.28.
  • 35
    • 47749105355 scopus 로고    scopus 로고
    • note
    • 2O 1 L; pH 7.2.] in slants or Petriplates at room temperature (28 ± 2 °C). The antibacterial activity of the compounds against human pathogens was evaluated by the agar diffusion method. About 1 ml of inoculum of each test pathogen was added to the molten Nutrient Agar (NA) medium and poured into sterile Petriplates under aseptic conditions. After solidification, a 5-mm well was made in the centre of each plate using a sterile cork borer. Each compound was dissolved in 10% DMSO to get different concentrations and filter was sterilized using 0.25 μm filter paper. Each well received 50 μL solution of each compound and the plates were incubated at room temperature. Sterile DMSO (10%) was used as control. After 48 h, the appearance of inhibition zone around the well was observed.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.