P. gingivalis and E. coli lipopolysaccharides exhibit different systemic but similar local induction of inflammatory markers

Journal of Periodontology

Volumn 79, Issue 7, 2008, Pages 1241-1247

  Liu, Rongkun ^a   Desta, Tesfahun ^a   Raptis, Markos ^a   Darveau, Richard P ^b   Graves, Dana T ^a  

^a BOSTON UNIVERSITY   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

Author keywords

Animal studies; Cytokine; Escherichia coli; Inflammation; Lipopolysaccharide; Periodontitis; Porphyromonas gingivalis

Indexed keywords

AUTACOID; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; INTERCELLULAR ADHESION MOLECULE 1; LIPOPOLYSACCHARIDE; TUMOR NECROSIS FACTOR ALPHA; VASCULAR CELL ADHESION MOLECULE 1;

ANIMAL; AORTA; ARTICLE; CLASSIFICATION; COMPARATIVE STUDY; CONNECTIVE TISSUE; DISEASE MODEL; ESCHERICHIA COLI; HEART MUSCLE; IMMUNOLOGY; MALE; MOUSE; MOUSE STRAIN; PORPHYROMONAS GINGIVALIS; SCALP; TIME;

ANIMALS; AORTA; CONNECTIVE TISSUE; DISEASE MODELS, ANIMAL; E-SELECTIN; ESCHERICHIA COLI; INFLAMMATION MEDIATORS; INTERCELLULAR ADHESION MOLECULE-1; LIPOPOLYSACCHARIDES; MALE; MICE; MICE, INBRED STRAINS; MYOCARDIUM; PORPHYROMONAS GINGIVALIS; SCALP; TIME FACTORS; TUMOR NECROSIS FACTOR-ALPHA; VASCULAR CELL ADHESION MOLECULE-1;

EID: 47749124964     PISSN: 00223492     EISSN: None     Source Type: Journal    
DOI: 10.1902/jop.2008.070575     Document Type: Article

References (21)

1. Darveau R, Cunningham M, Bailey T, et al. Ability of bacteria associated with chronic inflammatory disease to stimulate E-selectin expression and promote neutrophil adhesion. Infect Immun 1995;63:1311-1317.
2. Rietschel ET, Brade L, Brandenburg K, et al. Chemical structure and biologic activity of bacterial and synthetic lipid A. Rev Infect Dis 1987;9(Suppl. 5):S527-S536.
3. Schromm A, Brandenburg K, Loppnow H, et al. Biological activities of lipopolysaccharides are determined by the shape of their lipid A portion. Eur J Biochem 2000;267:2008-2013.
4. Rietschel ET, Brade H, Holst O, et al. Bacterial endotoxin: Chemical constitution, biological recognition, host response, and immunological detoxification. Curr Top Microbiol Immunol 1996;216:39-81.
5. Kumada H, Haishima Y, Umemoto T, Tanamoto K. Structural study on the free lipid A isolated from lipopolysaccharide of Porphyromonas gingivalis. J Bacteriol 1995;177:2098-2106.
6. Guo L, Lim KB, Gunn JS, et al. Regulation of lipid A modifications by Salmonella typhimurium virulence genes phoP-phoQ. Science 1997;276:250-253.
7. Ernst RK, Yi E, Guo L, et al. Specific lipopolysaccharide found in cystic fibrosis airway Pseudomonas aeruginosa. Science 1999;286:1561-1565.
8. Darveau RP, Pham TT, Lemley K, et al. Porphyromonas gingivalis lipopolysaccharide contains multiple lipid A species that functionally interact with both toll-like receptors 2 and 4. Infect Immun 2004;72:5041-5051.
9. Ogawa T, Asai Y, Yamamoto H, et al. Immunobiological activities of a chemically synthesized lipid A of Porphyromonas gingivalis. FEMS Immunol Med Microbiol 2000;28:273-281.
10. Ogawa T, Suda Y, Kashihara W, et al. Immunobiological activities of chemically defined lipid A from Helicobacter pylori LPS in comparison with Porphyromonas gingivalis lipid A and Escherichia coli-type synthetic lipid A (compound 506). Vaccine 1997;15:1598-1605.
11. Naguib G, Al-Mashat H, Desta T, Graves D. Diabetes prolongs the inflammatory response to a bacterial stimulus through cytokine dysregulation. J Invest Dermatol 2004;123:87-92.
12. Graves D, Naguib G, Lu H, Desta T, Amar S. Porphyromonas gingivalis fimbriae are pro-inflammatory but do not play a prominent role in the innate immune response to P. gingivalis. J Endotoxin Res 2005;11:13-18.
13. Nair BC, Mayberry WR, Dziak R, Chen PB, Levine MJ, Hausmann E. Biological effects of a purified lipopolysaccharide from Bacteroides gingivalis. J Periodontal Res 1983;18:40-49.
14. Tanamoto K, Azumi S, Haishima Y, Kumada H, Umemoto T. Endotoxic properties of free lipid A from Porphyromonas gingivalis. Microbiology 1997;143:63-71.
15. Reife RA, Coats SR, Al-Qutub M, et al. Porphyromonas gingivalis lipopolysaccharide lipid A heterogeneity: Differential activities of tetra- and penta-acylated lipid A structures on E-selectin expression and TLR4 recognition. Cell Microbiol 2006;8:857-868.
16. Manthey CL, Vogel SN. Interactions of lipopolysaccharide with macrophages. Immunol Ser 1994;60:63-81.
17. Zhou Q, Desta T, Fenton M, Graves DT, Amar S. Cytokine profiling of macrophages exposed to Porphyromonas gingivalis, its lipopolysaccharide, or its FimA protein. Infect Immun 2005;73:935-943.
18. Zubery Y, Dunstan C, Story B, et al. Bone resorption caused by three periodontal pathogens in vivo in mice is mediated in part by prostaglandin. Infect Immun 1998;66:4158-4162.
19. Huang J, Lin Y, Lai Y, Hu S. Lethal outcome caused by Porphyromonas gingivalis A7436 in a mouse chamber model is associated with elevated titers of host serum interferon-gamma. Oral Microbiol Immunol 2006;21:100-106.
20. Martin M, Katz J, Vogel SN, Michalek SM. Differential induction of endotoxin tolerance by lipopolysaccharides derived from Porphyromonas gingivalis and Escherichia coli. J Immunol 2001;167:5278-5285.
21. Gibson FC 3rd, Hong C, Chou HH, et al. Innate immune recognition of invasive bacteria accelerates atherosclerosis in apolipoprotein E-deficient mice. Circulation 2004;109:2801-2806.