Understanding medication compliance and persistence from an economics perspective

Value in Health

Volumn 11, Issue 4, 2008, Pages 600-610

  Elliott, Rachel A ^b   Shinogle, Judith A ^a   Peele, Pamela ^c   Bhosle, Monali ^d   Hughes, Dyfrig A ^e  

^a UNIVERSITY OF MARYLAND   (United States)

^b UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^c UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

^d OHIO STATE UNIVERSITY   (United States)

^e BANGOR UNIVERSITY   (United Kingdom)

Author keywords

Compliance; Economic theory; Medication use; Patient behavior

Indexed keywords

ADVERSE OUTCOME; BUDGET; CONSUMER; ECONOMIC EVALUATION; HEALTH BEHAVIOR; MODEL; PATIENT COMPLIANCE; PATIENT PARTICIPATION; PRESCRIPTION; PRIORITY JOURNAL; REVIEW; TREATMENT REFUSAL;

EID: 47749122686     PISSN: 10983015     EISSN: 15244733     Source Type: Journal    
DOI: 10.1111/j.1524-4733.2007.00304.x     Document Type: Article

References (94)

1. DiMatteo MR. Variations in patients' adherence to medical recommendations: a quantitative review of 50 years of research. Med Care 2004 42 : 200 9.
2. World Health Organization. Adherence to long-term therapies. Evidence for action. 2003. Available from: http://www.who.int/chp/en/ [Accessed May 7, 2005].
3. Haynes RB, McKibbon KA, Kanani R. Systematic review of randomised trials of interventions to assist patients to follow prescriptions for medications. Lancet 1996 348 : 383 6.
4. Haynes RB, McDonald H, Garg AX, Montague P. Interventions for helping patients to follow prescriptions for medications. Cochrane Database Syst Rev 2002 2 : CD000011.
5. Bender BG, Milgrom H, Apter AJ. Adherence intervention research: what have we learned and what do we do next? J Allergy Clin Immunol 2003 112 : 489 94.
6. Elliott RA, Barber N, Horne R. Cost-effectiveness of adherence-enhancing interventions: a quality assessment of the evidence. Ann Pharmacother 2005 39 : 508 15.
7. Bonner S, Zimmerman BJ, Evans D, et al. An individualised intervention to improve asthma management among urban Latino and African-American families. J Asthma 2002 39 : 493 500.
8. Gallefoss FR, Bakke PS. How does patient education and self-management among asthmatics and patients with chronic obstructive pulmonary disease affect medication? Am J Respir Crit Care Med 1999 160 : 2000 5.
9. Simon GE, Katon WJ, von Korff M, et al. Cost-effectiveness of a collaborative care program for primary care patients with persistent depression. Am J Psychiatry 2001 158 : 1638 44.
10. Nichol MB, Venturini F, Sung JCY. A critical evaluation of the methodology of the literature on medication compliance. Ann Pharmacother 1999 33 : 531 40.
11. Lee JK, Grace KA, Taylor AJ. Effect of a pharmacy care program on medication adherence and persistence, blood pressure, and low-density lipoprotein cholesterol: a randomized controlled trial. JAMA 2006 296 : 2563 71.
12. Kahneman D, Slovic P, Tversky A. Judgement under Uncertainty: Heuristics and Biases. Cambridge : Cambridge University Press, 1982.
13. Task Force on Medicines Partnership and the National Collaborative Medicines Management Services Programme. Room for Review: A Guide to Medication Review - The Agenda for Patients, Practitioners and Managers (1st ed.). London : Medicines Partnership, 2002.
14. Cramer JA, Roy A, Burrell A, et al. Medication Compliance and Persistence: terminology and definitions. 2007. Available from: doi: 10.1111/j.1524-4733.2007.00213x. [Accessed June 25, 2007].
15. Vedhara K, Wadsworth E, Norman P, et al. Habitual prospective memory in elderly patients with Type 2 diabetes: implications for medication adherence. Psychol Health Med 2004 9 : 17 28.
16. Isaac LM, Tamblyn RM. Compliance and cognitive function: a methodological approach to measuring unintentional errors in medication compliance in the elderly. McGill-Calgary Drug Research Team. Gerontologist 1993 33 : 772 81.
17. Barber N, Parsons J, Clifford S, et al. Patients' problems with new medication for chronic conditions. Qual Saf Health Care 2004 13 : 172 5.
18. Horne R, Weinman J, Barber N, et al. Concordance, Adherence and Compliance in Medicine Taking: A Conceptual Map and Research Priorities. London : National Co-ordinating Centre for NHS Service Delivery and Organisation NCCSDO, 2006.
19. Barber N, Safdar A, Franklin BD. Can human error theory explain non-adherence? Pharm World Sci 2005 27 : 300 4.
20. DiMatteo MR. Social support and patient adherence to medical treatment: a meta-analysis. Health Psychol 2004 23 : 207 18.
21. Soumerai SB. Unintended outcomes of Medicaid drug cost-containment policies on the chronically mentally ill. J Clin Psychiatry 2003 64 (Suppl. 17 S19 22.
22. Lexchin J, Grootendorst P. Effects of prescription drug user fees on drug and health services use and on health status in vulnerable populations: a systematic review of the evidence. Int J Health Serv 2004 34 : 101 22.
23. Donovan J, Blake DR. Patient non-compliance: deviance or reasoned decision-making. Soc Sci Med 1992 34 : 507 13.
24. Dowell J, Hudson H. A qualitative study of medicine-taking behaviour in primary care. Fam Pract 1997 14 : 369 75.
25. Pound P, Britten N, Morgan M, et al. Resisting medicines: a synthesis of qualitative studies of medicine taking. Soc Sci Med 2005 61 : 133 55.
26. Horne R, Weinman J. Patients' beliefs about prescribed medicines and their role in adherence to treatment in chronic physical illness. J Psychosom Res 1999 47 : 555 67.
27. Horne R, Weinman J, Hankins M. The beliefs about medicines questionnaire: the development of and evaluation of a new method for assessing the cognitive representation of medication. Psychol Health 1999 14 : 1 24.
28. Hand CH, Bradley C. Health beliefs of adults with asthma: toward an understanding of the difference between symptomatic and preventive use of inhaler treatment. J Asthma 1996 33 : 331 8.
29. Acton JP. Nonmonetary factors in the demand for medical services: some empirical evidence. J Polit Econ 1975 83 : 595 614.
30. Soumerai SB, Avorn J, Ross-Degnan D, Gortmaker S. Payment restrictions for prescription drugs under Medicaid. Effects on therapy, cost, and equity. N Engl J Med 1987 317 : 550 6.
31. Tamblyn R, Laprise R, Hanley JA, et al. Adverse events associated with prescription drug cost-sharing among poor and elderly persons. JAMA 2001 285 : 421 9.
32. Strickland WJ, Hanson CM. Coping with the cost of prescription drugs. J Health Care Poor Underserved 1996 7 : 50 62.
33. Cox ER, Henderson RR. Prescription use behaviour among Medicare beneficiaries with capped prescription benefits. J Manag Care Pharm 2002 8 : 360 4.
34. Lundberg L, Johannesson M, Isacson DGL, Borgquist L. Effects of user charges on the use of prescription medicines in different socio-economic groups. Health Policy 1998 44 : 123 34.
35. Krobot KJ, Miller WC, Kaufman JS, et al. The disparity in access to new medication by type of health insurance. Lessons from Germany. Med Care 2004 42 : 487 91.
36. Noyce PR, Huttin C, Atella V, et al. The cost of prescription medicines to patients. Health Policy 2000 52 : 129 45.
37. Schafheutle E. Do high prescription charges undermine compliance? Pharm J 2003 270 : 336 7.
38. Schafheutle EI, Hassell K, Noyce PR, Weiss MC. Access to medicines: cost as an influence on the views and behaviour of patients. Health Soc Care Community 2002 10 : 187 95.
39. Schafheutle E. The prescription charge: a barrier to treatment [editorial]. Prescriber 2003 14 : 10 13.
40. Phelps L. Unhealthy Charges. CAB Evidence on the Impact of Health Charges. London : National Association of Citizens Advice Bureaux, 2001.
41. Schafheutle EI, Hassell K, Seston EM, Noyce PR. Non-dispensing of NHS prescriptions in community pharmacies. Int J Pharm Pract 2002 10 : 11 15.
42. Guiffrida A, Torgerson DJ. Should we pay the patient? Review of financial incentives to enhance patient compliance. BMJ 1997 315 : 703 7.
43. Tulsky JP, Hahn JA, Long HL, et al. Can the poor adhere? Incentives for adherence to TB prevention in homeless adults. Int J Tuberc Lung Dis 2004 8 : 83 91.
44. Seal KH, Kral AH, Lorvick J, et al. A randomized controlled trial of monetary incentives vs. outreach to enhance adherence to the hepatitis B vaccine series among injection drug users. Drug Alcohol Depend 2003 71 : 127 31.
45. Rigsby MO, Rosen MI, Beauvais JE, et al. Cue-dose training with monetary reinforcement: pilot study of an antiretroviral adherence intervention. J Gen Intern Med 2000 15 : 841 7.
46. Hey K, Perera R. Competitions and incentives for smoking cessation. Cochrane Database Syst Rev 2005 2 : CD004307.
47. Giuffrida A, Gravelle HSE. Paying patients to comply: an economic analysis. Health Econ 1998 7 : 569 79.
48. Critchfield TS, Kollins SH. Temporal discounting: basic research and the analysis of socially important behavior. J App Behav Anal 2001 34 : 101 22.
49. Read D, Read NL. Time discounting over the lifespan. Organ Behav Hum Decis Process 2004 94 : 22 32.
50. Bleichrodt H, Gafni A. Time preference, the discounted utility model and health. J Health Econ 1996 15 : 49 66.
51. Christensen-Szalanski JJ, Northcraft GB. Patient compliance behavior: the effects of time on patients' values of treatment regimens. Soc Sci Med 1985 21 : 263 73.
52. Loewenstein G, Prelec D. Anomalies in intertemporal choice: evidence and an interpretation. Q J Econ 1992 107 : 573 97.
53. Samuelson PA. A note on measurement of utility. Rev Econ Stud 1937 4 : 155 61.
54. Angeletos G, Laibson D, Repetto A, et al. The hyperbolic consumption model: calibration, simulation, and empirical evaluation. J Economic Perspect 2001 15 : 47 68.
55. Baker F, Johnson MW, Bickel WK. Delay discounting in current and never-before cigarette smokers: similarities and differences across commodity, sign, and magnitude. J Abnorm Psychol 2003 112 : 382 90.
56. Smith PA. Are time preference and body mass index associated? Evidence from the national longitudinal survey of youth. Econ Hum Biol 2005 3 : 259 70.
57. Bishai DM. Does time preference change with age? J Popul Econ 2006 17 : 583 602.
58. Chapman GB, Brewer NT, Coups EJ, et al. Value for the future and preventive health behavior. J Exp Psychol 2001 7 : 235 50.
59. Becker GS. Investment in human capital: a theoretical analysis. J Polit Econ 1964 70 : 9 49.
60. Grossman M. The Human Capital Model of the demand for health. In : Newhouse J, Culyer AJ, eds. Handbook of Health Economics. Amsterdam : Elsevier Sciences B.V., 2000.
61. Ellrodt G, Cook DJ, Lee J, et al. Evidence-based disease management. JAMA 1997 278 : 1687 92.
62. Kehoe WA, Katz RC. Health behaviors and pharmacotherapy. Ann Pharmacother 1998 32 : 1076 86.
63. Nash J. Two-person cooperative games. Econometrica 1953 21 : 128 40.
64. Nash J. The bargaining problem. Econometrica 1950 18 : 155 62.
65. Tarrant C, Stokes T, Colman AM. Models of the medical consultation: opportunities and limitations of a game theory perspective. Qual Saf Health Care 2004 13 : 461 6.
66. Sonnenberg A. Special article: game theory to analyse management options in gastro-oesophageal disease. Aliment pharmacol Ther 2000 14 : 1411 17.
67. Sonnenberg A. Personal view: "don't ask, don't tell" - the undesirable consequences of incidental test results in gastroenterology. Aliment Pharmacol Ther 2004 20 : 381 7.
68. De JK, Jegers M. The physician-patient relationship as a game of strategic information transmission. Health Econ 2001 10 : 651 68.
69. Chao L-W. A comparison of consensus and nonconsensus approaches to modeling contraceptive choice behavior. Health Econ 2002 11 : 599 622.
70. Tirole J. The Theory of Industrial Organization. Cambridge, MA : MIT Press, 1990.
71. Ryan M, Scott DA, Reeves C, et al. Eliciting public preferences for healthcare: a systematic review of the techniques. Health Technol Assess 2001 5 : 1 186.
72. Ryan M, Gerard K. Using discrete choice experiments to value health care programmes: current practice and future research reflections. App Health Econ Health Policy 2003 2 : 55 64.
73. Ryan M, Farrar S. Using conjoint analysis to elicit preferences for health care. BMJ 2000 320 : 1530 3.
74. Aristides M, Chen J, Williamson E, et al. Conjoint analysis of a new chemotherapy: willingness to pay and preference for the features of Raltitrexed versus standard therapy in advanced colorectal cancer. Pharmacoeconomics 2002 20 : 775 84.
75. Gan TJ, Lubarsky DA, Flood EM, et al. Patient preferences for acute pain treatment. Br J Anaesth 2004 92 : 681 8.
76. Johansson G, Stallberg B, Tornling G, et al. Asthma treatment preference study: a conjoint analysis of preferred drug treatments. Chest 2004 125 : 916 23.
77. Kleinman L, McIntosh E, Ryan M, et al. Willingness to pay for complete symptom relief of gastroesophageal reflux disease. Arch Intern Med 2002 162 : 1361 6.
78. McKenzie L, Cairns J, Osman L. Symptom-based outcome measures for asthma: the use of discrete choice methods to assess patient preferences. Health Policy 2001 57 : 193 204.
79. Osman LM, McKenzie L, Cairns J, et al. Patient weighting of importance of asthma symptoms. Thorax 2001 56 : 138 42.
80. Ratcliffe J, Van Haselen R, Buxton M, et al. Assessing patients' preferences for characteristics associated with homeopathic and conventional treatment of asthma: a conjoint analysis study. Thorax 2002 57 : 503 8.
81. Sculpher M, Bryan S, Fry P, et al. Patients' preferences for the management of non-metastatic prostate cancer: discrete choice experiment. BMJ 2004 328 : 382 6.
82. Taylor S, Armour C. Consumer preference for dinoprostone vaginal gel using stated preference discrete choice modelling. Pharmacoeconomics 2003 21 : 721 35.
83. Mark TL, Swait J. Using stated preference modelling to forecast the effect of medication attributes on prescriptions of alcoholism medications. Value Health 2003 6 : 474 82.
84. Vick S, Scott A. Agency in health care. Examining patients' preferences for attributes of the doctor-patient relationship. J Health Econ 1998 17 : 587 605.
85. Watson V, Ryan M, Brown CT, et al. Eliciting preferences for drug treatment of lower urinary tract symptoms associated with benign prostatic hyperplasia. J Urol 2004 172 : 2321 5.
86. Ratcliffe J, Buxton M, McGarry T, et al. Patients' preferences for characteristics associated with treatments for osteoarthritis. Rheumatology 2004 43 : 337 45.
87. Mantel-Teeuwisse AK, Goettsch WG, Klungel OH, et al. Long term persistence with statin treatment in daily medical practice. Heart 2004 90 : 1065 6.
88. Caro JJ, Salas M, Speckman JL, et al. Persistence with treatment for hypertension in actual practice. CMAJ 1999 160 : 31 7.
89. Caldow J, Bond C, Ryan M, et al. Treatment of minor illness in primary care: a national survey of patient satisfaction, attitudes and preferences regarding a wider nursing role. Health Expect 2007 10 : 30 45.
90. Seston EM, Elliott RA, Noyce P, Payne K. Women's Preferences for the Provision of Emergency Hormonal Contraception Services. Pharmacy World & Science, 2007. Available from: http://dx.doi.org/10.1007/s11096-006-9068-9 [Accessed December 15, 2006].
91. Kahneman D, Tversky A. Prospect theory: an analysis of decision under risk. Econometrica 1979 47 : 263 92.
92. Thaler RH. Mental accounting and consumer choice. Mark Sci 1985 4 : 199 214.
93. Feeny D, Eng K. A test of prospect theory. Int J Technol Assess Health Care 2005 21 : 511 16.
94. Winter L, Lawton MP, Ruckdeschel G. Preferences for prolonging life: a prospect theory approach. Inter J Aging Hum Dev 2003 56 : 155 70.