Absence of evidence for an association between resistin gene variants and insulin resistance in an Asian population with low and high blood pressure

Diabetes Research and Clinical Practice

Volumn 81, Issue 2, 2008, Pages 231-237

  Kimbell, Jennifer L ^a   Koropatnick, Tanya A ^a   Grove, John S ^b   Huang, Yung Hsiang ^c   Chiang, Fu Tien ^d   Quertermous, Thomas ^e   Chen, Randi ^a   Donlon, Timothy A ^a,f   Rodriguez, Beatriz L ^a,b,f   Curb, J David ^a,b,f  

^a PACIFIC HEALTH RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF HAWAII   (United States)

^c NATIONAL HEALTH RESEARCH INSTITUTES   (Taiwan)

^d NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

^e STANFORD UNIVERSITY   (United States)

^f KUAKINI MEDICAL CENTER   (United States)

Author keywords

Asian population; Hypertension; Insulin resistance; Resistin; Single nucleotide polymorphisms

Indexed keywords

GLUCOSE; INSULIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL;

ADULT; ARTICLE; BODY MASS; CHINESE; CONFIDENCE INTERVAL; CONTROLLED STUDY; FEMALE; GENE; HUMAN; HYPERTENSION; HYPOTENSION; INSULIN RESISTANCE; JAPANESE; MAJOR CLINICAL STUDY; MALE; PHENOTYPE; REGRESSION ANALYSIS; RESISTIN GENE; SIBLING; SINGLE NUCLEOTIDE POLYMORPHISM;

ADULT; ANIMALS; ASIAN CONTINENTAL ANCESTRY GROUP; CHINA; DIABETES MELLITUS, TYPE 2; FEMALE; GENOTYPE; HUMANS; HYPERTENSION; HYPOTENSION; INSULIN RESISTANCE; JAPAN; MALE; MICE; POLYMORPHISM, SINGLE NUCLEOTIDE; RESISTIN; SIBLINGS; VARIATION (GENETICS);

EID: 47649131570     PISSN: 01688227     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.diabres.2008.04.001     Document Type: Article

References (26)

1. Phillips C., Lopez-Miranda J., Perez-Jimenez F., McManus R., and Roche H.M. Genetic and nutrient determinants of the metabolic syndrome. Curr. Opin. Cardiol. 21 (2006) 185-193
2. Steppan C.M., Bailey S.T., Bhat S., Brown E.J., Banerjee R.R., Wright C.M., et al. The hormone resistin links obesity to diabetes. Nature 409 (2001) 307-312
3. McTernan P.G., Kusminski C.M., and Kumar S. Resistin. Curr. Opin. Lipidol. 17 (2006) 170-175
4. Conneely K.N., Silander K., Scott L.J., Mohlke K.L., Lazaridis K.N., Valle T.T., et al. Variation in the resistin gene is associated with obesity and insulin-related phenotypes in Finnish subjects. Diabetologia 47 (2004) 1782-1788
5. Kunnari A., Ukkola O., and Kesaniemi Y.A. Resistin polymorphisms are associated with cerebrovascular disease in Finnish Type 2 diabetic patients. Diabet. Med. 22 (2005) 583-589
6. Pizzuti A., Argiolas A., Di Paola R., Baratta R., Rauseo A., Bozzali M., et al. An ATG repeat in the 3′-untranslated region of the human resistin gene is associated with a decreased risk of insulin resistance. J. Clin. Endocrinol. Metab. 87 (2002) 4403-4406
7. Wang H., Chu W.S., Hemphill C., and Elbein S.C. Human resistin gene: molecular scanning and evaluation of association with insulin sensitivity and type 2 diabetes in Caucasians. J. Clin. Endocrinol. Metab. 87 (2002) 2520-2524
8. Azuma K., Oguchi S., Matsubara Y., Mamizuki T., Murata M., Kikuchi H., et al. Novel resistin promoter polymorphisms: association with serum resistin level in Japanese obese individuals. Horm. Metab. Res. 36 (2004) 564-570
9. Urbanek M., Du Y., Silander K., Steppan C.M., Strauss III J.F., Dunaif A., et al. Variation in resistin gene promoter not associated with polycystic ovary syndrome. Diabetes 52 (2003) 214-217
10. Gouni-Berthold I., Giannakidou E., Faust M., Kratzsch J., Berthold H.K., Krone W., et al. Resistin gene 3′-untranslated region +62G → A polymorphism is associated with hypertension but not diabetes mellitus type 2 in a German population. J. Intern. Med. 258 (2005) 518-526
11. Osawa H., Tabara M.Y., Kawamoto R., Ohashi J., Ochi M., Onuma H., et al. Plasma resistin, associated with single nucleotide polymorphism -420, is correlated with insulin resistance, lower HDL cholesterol, and high-sensitivity C-reactive protein in the Japanese general population. Diabetes Care 30 (2007) 1501-1506
12. Norata G., Ongari M., Garlaschelli K., Tibolla G., Grigore G., Raselli S., et al. Effect of the -420C/G variant of the resistin gene promoter on metabolic syndrome, obesity, myocardial infarction and kidney dysfunction. J. Intern. Med. 262 (2007) 104-112
13. Wu K.D., Hsiao C.F., Ho L.T., Sheu W.H., Pei D., Chuanq L.M., et al. Clustering and heritability of insulin resistance in Chinese and Japanese hypertensive families: a Stanford-Asian Pacific Program in hypertension and insulin resistance sibling study. Hypertens. Res. 25 (2002) 529-536
14. Ranade K., Hsuing A.C., Wu K.D., Chang M.S., Chen Y.T., Hebert J., et al. Lack of evidence for an association between alpha-adducin and blood pressure regulation in Asian populations. Am. J. Hypertens. 13 (2000) 704-709
15. Kamath V., Jones C.N., Yip J.C., Varasteh B.B., Cincotta A.H., Reaven G.M., et al. Effects of a quick-release form of bromocriptine (Ergoset) on fasting and postprandial plasma glucose, insulin, lipid, and lipoprotein concentrations in obese nondiabetic hyperinsulinemic women. Diabetes Care 20 (1997) 1697-1701
16. Ewing B., Hillier L., Wendl M.C., and Green P. Base-calling of automated sequencer traces using phred. I. Accuracy assessment. Genome Res. 8 (1998) 175-185
17. P. Green, Documentation for PHRAP and CROSS_MATCH, http://www.phrap.org/phrap.docs/phrap.html, 1994.
18. Nickerson D.A., Tobe V.O., and Taylor S.L. PolyPhred: automating the detection and genotyping of single nucleotide substitutions using fluorescence-based resequencing. Nucleic Acids Res. 25 (1997) 2745-2751
19. Liang K.-Y., and Zeger S.L. Longitudinal data analysis using generalized linear models. Biometrika 73 (1986) 13-22
20. Cho Y.M., Youn B.S., Chung S.S., Kim K.W., Lee H.K., Yu K.-Y., et al. Common genetic polymorphisms in the promoter of resistin gene are major determinants of plasma resistin concentrations in humans. Diabetologia 47 (2004) 559-565
21. Engert J.C., Vohl M.C., Williams S.M., Lepage P., Loredo-Osti J.C., Faith J., et al. 5′ flanking variants of resistin are associated with obesity. Diabetes 51 (2002) 1629-1634
22. Ma X., Warram J.H., Trischitta V., and Doria A. Genetic variants at the resistin locus and risk of type 2 diabetes in Caucasians. J. Clin. Endocrinol. Metab. 87 (2002) 4407-4410
23. Ochi M., Osawa H., Onuma H., Murakami A., Nishimiya T., Shimada F., et al. The absence of evidence for major effects of the frequent SNP +299G > A in the resistin gene on susceptibility to insulin resistance syndrome associated with Japanese type 2 diabetes. Diabetes Res. Clin. Pract. 61 (2003) 191-198
24. Osawa H., Onuma H., Murakami A., Ochi M., Nishimiya T., Kato K., et al. Systematic search for single nucleotide polymorphisms in the resistin gene: the absence of evidence for the association of three identified single nucleotide polymorphisms with Japanese type 2 diabetes. Diabetes 51 (2002) 863-866
25. Sentinelli F., Romeo S., Arca M., Filippi E., Leonetti F., Banchieri M., et al. Human resistin gene, obesity, and type 2 diabetes: mutation analysis and population study. Diabetes 51 (2002) 860-862
26. Osawa H., Yamada K., Onuma H., Murakami A., Ochi M., Kawata H., et al. The G/G genotype of a resistin single-nucleotide polymorphism at -420 increases type 2 diabetes mellitus susceptibility by inducing promoter activity through specific binding of Sp1/3. Am. J. Hum. Genet. 75 (2004) 678-686