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Volumn 112, Issue 2, 2008, Pages 444-445

Conflicting data on the prognostic significance of FLT3/TKD mutations in acute myeloid leukemia might be related to the incidence of biallelic disease

Author keywords

[No Author keywords available]

Indexed keywords

CD135 ANTIGEN; PROTEIN TYROSINE KINASE; FLT3 PROTEIN, HUMAN;

EID: 47649131141     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2008-02-140392     Document Type: Letter
Times cited : (34)

References (10)
  • 1
    • 38949212204 scopus 로고    scopus 로고
    • FLT3 D835/I836 mutations are associated with poor disease-free survival and a distinct gene-expression signature among younger adults with de novo cytogenetically normal acute myeloid leukemia lacking FLT3 internal tandem duplications
    • Whitman SP, Ruppert AS, Radmacher MD, et al. FLT3 D835/I836 mutations are associated with poor disease-free survival and a distinct gene-expression signature among younger adults with de novo cytogenetically normal acute myeloid leukemia lacking FLT3 internal tandem duplications. Blood. 2008;111: 1552-1559.
    • (2008) Blood , vol.111 , pp. 1552-1559
    • Whitman, S.P.1    Ruppert, A.S.2    Radmacher, M.D.3
  • 2
    • 34548029756 scopus 로고    scopus 로고
    • FLT3 tyrosine kinase domain mutations are biologically distinct from and have a significantly more favorable prognosis than FLT3 internal tandem duplications in patients with acute myeloid leukemia
    • Mead AJ, Linch DC, Hills RK, Wheatley K, Burnett AK, Gale RE. FLT3 tyrosine kinase domain mutations are biologically distinct from and have a significantly more favorable prognosis than FLT3 internal tandem duplications in patients with acute myeloid leukemia. Blood. 2007;110:1262-1270.
    • (2007) Blood , vol.110 , pp. 1262-1270
    • Mead, A.J.1    Linch, D.C.2    Hills, R.K.3    Wheatley, K.4    Burnett, A.K.5    Gale, R.E.6
  • 3
    • 1642301466 scopus 로고    scopus 로고
    • Heterogeneous patterns of FLT3 Asp(835) mutations in relapsed de novo acute myeloid leukemia: A comparative analysis of 120 paired diagnostic and relapse bone marrow samples
    • Shih LY, Huang CF, Wu JH, et al. Heterogeneous patterns of FLT3 Asp(835) mutations in relapsed de novo acute myeloid leukemia: a comparative analysis of 120 paired diagnostic and relapse bone marrow samples. Clin Cancer Res. 2004;10:1326-1332.
    • (2004) Clin Cancer Res , vol.10 , pp. 1326-1332
    • Shih, L.Y.1    Huang, C.F.2    Wu, J.H.3
  • 4
    • 24944590535 scopus 로고    scopus 로고
    • Rapid and sensitive detection of internal tandem duplication and activating loop mutations of FLT3
    • Mills Kl, Gilkes AF, Walsh V, Sweeney M, Gale R. Rapid and sensitive detection of internal tandem duplication and activating loop mutations of FLT3. Br J Haematol. 2005;130:203-208.
    • (2005) Br J Haematol , vol.130 , pp. 203-208
    • Mills, K.1    Gilkes, A.F.2    Walsh, V.3    Sweeney, M.4    Gale, R.5
  • 5
    • 41949090673 scopus 로고    scopus 로고
    • The impact of FLT3 internal tandem duplication mutant level, number, size and interaction with NPM1 mutations in a large cohort of young adult patients with acute myeloid leukemia
    • Gale RE, Green C, Allen G, et al. The impact of FLT3 internal tandem duplication mutant level, number, size and interaction with NPM1 mutations in a large cohort of young adult patients with acute myeloid leukemia. Blood. 2008;111:2776-2784.
    • (2008) Blood , vol.111 , pp. 2776-2784
    • Gale, R.E.1    Green, C.2    Allen, G.3
  • 6
    • 0035476264 scopus 로고    scopus 로고
    • Absence of the wild-type allele predicts poor prognosis in adult de novo acute myeloid leukemia with normal cytogenetics and the internal tandem duplication of FLT3: A cancer and leukemia group B study
    • Whitman SP, Archer KJ, Feng L, et al. Absence of the wild-type allele predicts poor prognosis in adult de novo acute myeloid leukemia with normal cytogenetics and the internal tandem duplication of FLT3: a cancer and leukemia group B study. Cancer Res. 2001;61:7233-7239.
    • (2001) Cancer Res , vol.61 , pp. 7233-7239
    • Whitman, S.P.1    Archer, K.J.2    Feng, L.3
  • 7
    • 0037097716 scopus 로고    scopus 로고
    • Analysis of FLT3-activating mutations in 979 patients with acute myelogenous leukemia: Association with FAB subtypes and identification of subgroups with poor prognosis
    • Thiede C, Steudel C, Mohr B, et al. Analysis of FLT3-activating mutations in 979 patients with acute myelogenous leukemia: association with FAB subtypes and identification of subgroups with poor prognosis. Blood. 2002;99:4326-4335.
    • (2002) Blood , vol.99 , pp. 4326-4335
    • Thiede, C.1    Steudel, C.2    Mohr, B.3
  • 8
    • 33845254595 scopus 로고    scopus 로고
    • Clinical implications of FLT3 mutations in pediatric AML
    • Meshinchi S, Alonzo TA, Stirewalt DL, et al. Clinical implications of FLT3 mutations in pediatric AML. Blood. 2006;108:3654-3661.
    • (2006) Blood , vol.108 , pp. 3654-3661
    • Meshinchi, S.1    Alonzo, T.A.2    Stirewalt, D.L.3
  • 9
    • 12544257171 scopus 로고    scopus 로고
    • Genome-wide single nucleotide polymorphism analysis reveals frequent partial uniparental disomy due to somatic recombination in acute myeloid leukemias
    • Raghavan M, Lillington DM, Skoulakis S, et al. Genome-wide single nucleotide polymorphism analysis reveals frequent partial uniparental disomy due to somatic recombination in acute myeloid leukemias. Cancer Res. 2005;65:375-378.
    • (2005) Cancer Res , vol.65 , pp. 375-378
    • Raghavan, M.1    Lillington, D.M.2    Skoulakis, S.3
  • 10
    • 44449151696 scopus 로고    scopus 로고
    • Gupta M, Raghavan M, Gale RE, et al. Novel regions of acquired uniparental disomy discovered in acute myeloid leukemia. Genes Chromosomes Cancer. Prepublished on May 27, 2008 as doi 10.1002/qcc.20573.
    • Gupta M, Raghavan M, Gale RE, et al. Novel regions of acquired uniparental disomy discovered in acute myeloid leukemia. Genes Chromosomes Cancer. Prepublished on May 27, 2008 as doi 10.1002/qcc.20573.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.