Experimental diabetes enhances Ca2+ mobilization and glutamate exocytosis in cerebral synaptosomes from mice

Diabetes Research and Clinical Practice

Volumn 81, Issue 2, 2008, Pages

  Satoh, Eiki ^a   Takahashi, Ayako ^a  

^a OBIHIRO UNIVERSITY OF AGRICULTURE AND VETERINARY MEDICINE   (Japan)

Author keywords

Ca2+ channel; Cerebral synaptosome; Cytosolic free Ca2+; Diabetes; Glutamate release

Indexed keywords

4 AMINOPYRIDINE; CALCIUM CHANNEL N TYPE; CALCIUM CHANNEL P TYPE; CALCIUM ION; FURA 2; GLUTAMIC ACID; OMEGA AGATOXIN IVA; OMEGA CONOTOXIN GVIA; POTASSIUM ION; STREPTOZOCIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN CORTEX; CALCIUM MOBILIZATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; EXOCYTOSIS; EXPERIMENTAL DIABETES MELLITUS; MALE; MEMBRANE DEPOLARIZATION; MOUSE; NERVE ENDING; NONHUMAN; STREPTOZOCIN DIABETES; SYNAPTOSOME;

ANIMALS; BRAIN; CALCIUM; CALCIUM CHANNEL BLOCKERS; DIABETES MELLITUS, EXPERIMENTAL; EXOCYTOSIS; GLUTAMIC ACID; KINETICS; MALE; MICE; MICE, INBRED STRAINS; OMEGA-AGATOXIN IVA; POTASSIUM; SYNAPTOSOMES;

EID: 47649127364     PISSN: 01688227     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.diabres.2008.04.017     Document Type: Article

References (20)

1. Biessels G.J., van der Heide L.P., Kamal A., Bleys R.L.A.W., and Gispen W.H. Aging and diabetes: implications for brain function. Eur. J. Pharmacol. 441 (2002) 1-14
2. Blaustein M.P. Calcium transport and buffering in neurons. Trends Neurosci. 11 (1988) 438-443
3. Llinas R.R. Depolarization release coupling: an overview. Ann. N. Y. Acad. Sci. 635 (1991) 3-17
4. Bliss T.V., and Collingridge G.L. A synaptic model of memory: long-term potentiation in the hippocampus. Nature 361 (1993) 31-39
5. Lipton S.A., and Rosenberg P.A. Excitatory amino acids as a final common pathway for neurologic disorders. N. Engl. J. Med. 330 (1994) 613-622
6. Hajos F. An improved method for the preparation of synaptosomal fractions in high purity. Brain Res. 93 (1975) 485-489
7. Bradford M.M. Rapid and sensitive method for quantitation of microgram quantities of protein using the principle of protein-dye binding. Anal. Biochem. 72 (1976) 248-254
8. 2+ levels in cerebrocortical synaptosomes of rats. J. Neurochem. 57 (1991) 1270-1275
9. Nicholls D.G., Sihra T.S., and Sanchez-Prieto J. Calcium-dependent and -independent release of glutamate from synaptosomes monitored by continuous fluorometry. J. Neurochem. 49 (1987) 50-57
10. 2+ and glutamate release. J. Neurochem. 53 (1989) 1693-1699
11. Vazquez E., and Sanchez-Prieto J. Presynaptic modulation of glutamate release targets different calcium channels in rat cerebrocortical nerve terminals. Eur. J. Neurosci. 9 (1997) 2009-2018
12. Wang S.-J. Facilitatory effect of aspirin on glutamate release from rat hippocampal nerve terminals: involvement of protein kinase C pathway. Neurochem. Int. 48 (2006) 181-190
13. Voitenko N.V., Kruglikov I.A., Kostyuk E.P., and Kostyuk P.G. Effect of streptozotocin-induced diabetes on the activity of calcium channels in rat dorsal horn neurons. Neuroscience 95 (2000) 519-524
14. Hall K.E., Sima A.A.F., and Wiley J.W. Voltage-dependent calcium currents are enhanced in dorsal root ganglion neurons from the Bio Bred/Worchester diabetic rat. J. Physiol. 486 (1995) 313-322
15. Hall K.E., Liu J., Sima A.A.F., and Wiley J.W. Impaired inhibitory G-protein function contributes to increased calcium currents in rats with diabetic neuropathy. J. Neurophysiol. 86 (2001) 760-770
16. Luebke J.I., Dunlap K., and Turner T.J. Multiple calcium channel types control glutamatergic synaptic transmission in the hippocampus. Neuron 11 (1993) 895-902
17. Turner T.J., and Dunlap K. Pharmacological characterization of presynaptic calcium channels using subsecond biochemical measurements of synaptosomal neurosecretion. Neuropharmacology 34 (1995) 1469-1478
18. Danbolt N.C. Glutamate uptake. Prog. Neurobiol. 65 (2001) 1-105
19. Duarte A.I., Santos M.S., Seica R., and Oliveira C.R. Effect of oxidative stress on the uptake of GABA and glutamate in synaptosomes isolated from diabetic rat brain. Neuroendocrinology 72 (2000) 179-186
20. Duarte A.I., Santos M.S., Seica R., and Oliveira C.R. Oxidative stress affects synaptosomal γ-aminobutyric acid and glutamate transport in diabetic rats. The role of insulin. Diabetes 53 (2004) 2110-2116