Extracellular matrix secreted by senescent fibroblasts induced by UVB promotes cell proliferation in HaCaT cells through PI3K/AKT and ERK signaling pathways

International Journal of Molecular Medicine

Volumn 21, Issue 6, 2008, Pages 777-784

  Kang, Jian ^a   Chen, Wenqi ^a   Xia, Jiping ^a   Li, Yanhua ^a   Yang, Bon ^a   Chen, Bin ^a   Sun, Weiling ^a   Song, Xiuzu ^b   Xiang, Wenzhong ^b   Wang, Xiaoyong ^c   Wang, Fei ^d   Bi, Zhigang ^a   Wan, Yinsheng ^e  

^a NANJING MEDICAL UNIVERSITY   (China)

^b Third Hospital of Hangzhou   (China)

^c ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

^d AFFILIATED ZHONGDA HOSPITAL OF SOUTHEAST UNIVERSITY   (China)

^e PROVIDENCE COLLEGE   (United States)

Author keywords

AKT; Extracellular matrix; Extracellular signal regulated kinase; Senescence; Tumorigenesis; Ultraviolet

Indexed keywords

CYTOCHALASIN D; CYTOSKELETON PROTEIN; FOCAL ADHESION KINASE; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PROTEIN KINASE B; PROTEIN KINASE B INHIBITOR; ENZYME INHIBITOR; FOCAL ADHESION KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE KINASE;

AGING; ARTICLE; CELL PROLIFERATION; CELL STIMULATION; CONTROLLED STUDY; CYTOSKELETON; DRUG MECHANISM; ENZYME ACTIVATION; EXTRACELLULAR MATRIX; HUMAN; HUMAN CELL; KERATINOCYTE; PRECANCER; PRIORITY JOURNAL; RADIATION CARCINOGENESIS; SENESCENCE; SIGNAL TRANSDUCTION; SKIN CANCER; SKIN CARCINOGENESIS; SKIN FIBROBLAST; SUN EXPOSURE; ULTRAVIOLET B RADIATION; APOPTOSIS; CELL AGING; CELL DIFFERENTIATION; CELL LINE; CELL TRANSFORMATION; CUTANEOUS PARAMETERS; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; FIBROBLAST; FLOW CYTOMETRY; METABOLISM; PHYSIOLOGY; RADIATION EXPOSURE; SECRETION; SKIN; ULTRAVIOLET RADIATION; WESTERN BLOTTING;

1-PHOSPHATIDYLINOSITOL 3-KINASE; APOPTOSIS; BLOTTING, WESTERN; CELL AGING; CELL DIFFERENTIATION; CELL LINE; CELL PROLIFERATION; CELL TRANSFORMATION, NEOPLASTIC; ENZYME INHIBITORS; EXTRACELLULAR MATRIX; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FIBROBLASTS; FLOW CYTOMETRY; FOCAL ADHESION KINASE 1; HUMANS; KERATINOCYTES; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; SKIN; SKIN AGING; ULTRAVIOLET RAYS;

EID: 47649125992     PISSN: 11073756     EISSN: None     Source Type: Journal    
DOI: 10.3892/ijmm.21.6.777     Document Type: Article

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