Severe cytoplasmic abnormalities of the oocyte decrease cryosurvival and subsequent embryonic development of cryopreserved embryos

Human Reproduction

Volumn 23, Issue 8, 2008, Pages 1778-1785

  Balaban, B ^a   Ata, B ^a   Isiklar, A ^a   Yakin, K ^a   Urman, B ^a  

^a AMERICAN HOSPITAL   (Turkey)

Author keywords

Blastocyst quality; Cryopreservation; Cytoplasmic abnormality; Hatching blastocyst; Oocyte morphology

Indexed keywords

ARTICLE; BLASTOCYST; CELL GRANULE; CELL SHAPE; CELL STRUCTURE; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; CORRELATION ANALYSIS; CRYOPRESERVATION; CYTOPATHOLOGY; CYTOPLASM; EMBRYO; EMBRYO DEVELOPMENT; HATCHING; HUMAN; HUMAN CELL; HUMAN TISSUE; OOCYTE; QUALITY CONTROL; THAWING; TISSUE CULTURE; VITELLINE MEMBRANE;

EID: 47649123991     PISSN: 02681161     EISSN: 14602350     Source Type: Journal    
DOI: 10.1093/humrep/den127     Document Type: Article

References (28)

1. Anderson A, Weikert M, Crain J. Determining the most optimal stage for embryo cryopreservation. Reprod Biomed Online 2004;8:207-211.
2. Balaban B, Urman B. Comparison of two sequential media for culturing cleavage stage embryos and blastocysts: embryo characteristics and clinical outcome. Reprod Biomed Online 2005;10:485-491.
3. Balaban B, Urman B. Effect of oocyte morphology on embryo development and implantation. Reprod Biomed Online 2006;12:608-615.
4. Balaban B, Yakin K, Isiklar A, Urman B. Utilization of high-security straws for embryo freezing in an in vitro fertilization program: a prospective, randomized study. Fertil Steril 2007;87:691-696.
5. Ebner T, Moser M, Sommergruber M, Gaiswinkler U, Shebl O, Jesacher K, Tews G. Occurrence and developmental consequences of vacuoles throughout preimplantation development. Fertil Steril 2005;83: 1635-1640.
6. Ebner T, Moser M, Tews G. Is oocyte morphology prognostic of embryo developmental potential after ICSI? Reprod Biomed Online 2006;12:507-512.
7. Ebner T, Moser M, Shebl O, Sommerguber M, Tews G. Prognosis of oocytes showing aggregation of smooth endoplasmic reticulum. Reprod Biomed Online 2008a;16:113-118.
8. Ebner T, Shebl O, Moser M, Sommergruber M, Tews G. Developmental fate of ovoid oocytes. Hum Reprod 2008b;23:62-66.
9. Gardner D, Schoolcraft W. In vitro culture of human blastocyst. In: Jansen R, Mortimer D(eds). Towards Reproductive Certainty: Infertility and Genetics Beyond 1999. Carnforth: Parthenon Press, 1999,378-388.
10. Gosden R, Trasler J, Lucifero D, Faddy M. Rare congenital disorders, imprinted genes, and assisted reproductive technology. Lancet 2003;361:1975-1977.
11. Kahraman S, Yakin K, Donmez E, Samli H, Bahce M, Cengiz G, Sertyel S, Samli M, Imirzalioglu N. Relationship between granular cytoplasm of oocytes and pregnancy outcome following intracytoplasmic sperm injection. Hum Reprod 2000;15:2390-2393.
12. Karlström P, Bergh T, Forsberg A, Sandkvist U, Wikland M. Prognostic factors for the success rate of embryo freezing. Hum Reprod 1997;12:1263-1266.
13. Maher E, Afran M, Barratt C. Epigenetic risks related to assisted reproductive technologies: epigenetics, imprinting, AR and icebergs? Hum. Reprod. 2003;18:2508-2511.
14. Meriano J, Alexis J, Visram-Zaver S, Cruz M, Casper R. Tracking of oocyte dysmorphisms for ICSI patients may prove relevant to the outcome in subsequent patient cycles. Hum Reprod 2001;16:2118-2123.
15. Otsuki J, Okada A, Morimoto K, Nagai Y, Kubo H. The relationship between the pregnancy outcome and smooth endoplasmic reticulum clusters in MII human oocytes. Hum Reprod 2004;19:1591-1597.
16. Rienzi L, Nagy Z, Ubaldi F, Iacobelli M, Anniballo R, Tesarik J, Greco E. Laser-assisted removal of necrotic blastomeres from cryopreserved embryos that were partially damaged. Fertil Steril 2002;77:1196-1201.
17. Salumets A, Tuuri T, Makinen S, Vilska S, Husu L, Taino R, Suikkari A. Effect of developmental stage of embryo at freezing on pregnancy outcome of frozen-thawed embryo transfer. Hum Reprod 2003;18:1890-1895.
18. Sathananthan A, Ng S, Bongso A, Trounson A, Ratnam S. Visual Atlas of Early Human Development for Assisted Reproductive Technology. Singapore: Serono, 1993.
19. Serhal PF, Ranieri DM, Kinis A, Marchant S, Davies M, Khadum IM. Oocyte morphology predicts outcome of intracytoplasmic sperm injection. Hum Reprod 1997;12:1267-1270.
20. Sundstrom P, Nilsson M. Sequential changes in cytoplasmic features during maturation of the human oocyte. In: Motta P(ed). Developments in Ultrastructure of Reproduction. New York: Alan R Liss, 1989,327-333.
21. Urman B, Balaban B, Yakin K. Impact of fresh cycle variables on the implantation potential of cryopreserved-thawed human embryos. Fertil Steril 2007;87:310-315.
22. Van Blerkom J. Occurrence and developmental consequences of aberrant cellular organization in meiotically mature human oocytes after exogenous ovarian hyperstimulation. J Electron Microsc Technol 1990;16:324- 346.
23. Van Blerkom J, Henry G. Oocyte dysmorphism and aneuploidy in meiotically mature human oocytes after ovarian stimulation. Hum Reprod 1992;7:379-390.
24. Van Blerkom J, Antczak M, Schrader R. The developmental potential of the human oocyte is related to the dissolved oxygen content of follicular fluid: association with vascular endothelial growth factor levels and perifollicular blood flow characteristics. Hum Reprod 1997;12:1047-1055.
25. Veeck L. Does developmental stage at freeze impact on clinical results post-thaw? Reprod Biomed Online 2003;6:367-374.
26. Veeck L. Oocyte assessment and biological performance. Ann NY Acad Sci 1998;541:259-274.
27. Wells D, Bermudez M, Steuerwald N, Malter H, Thornhill A, Cohen J. Association of abnormal morphology and altered gene expression in human preimplantation embryos. Fertil Steril 2005;84:343-355.
28. Yakin K, Balaban B, Isiklar A, Urman B. Oocyte dysmorphism is not associated with aneuploidy in the developing embryo. Fertil Steril 2007;88:811-816.