Endoscopic ultrasound-guided ethanol injection in the pancreas in a porcine model: A preliminary study

Journal of Gastroenterology and Hepatology (Australia)

Volumn 23, Issue 7 PT2, 2008, Pages

  Matsumoto, Kakuya ^a,b   Yamao, Kenji ^a   Okubo, Kenji ^a   Hara, Kazuo ^a   Sawaki, Akira ^a   Mizuno, Nobumasa ^a   Tajika, Masahiro ^a   Kawai, Hiroki ^a   Ashida, Reiko ^a  

^a AICHI CANCER CENTER HOSPITAL   (Japan)

^b ASAHIKAWA MEDICAL COLLEGE   (Japan)

Author keywords

Endoscopic ultrasound; Ethanol injection; Pancreas; Porcine model; Preliminary study

Indexed keywords

ALANINE AMINOTRANSFERASE; ALCOHOL; ALKALINE PHOSPHATASE; AMYLASE; ASPARTATE AMINOTRANSFERASE; LACTATE DEHYDROGENASE;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALKALINE PHOSPHATASE BLOOD LEVEL; AMYLASE BLOOD LEVEL; ANESTHESIA; ANIMAL EUTHANASIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BODY WEIGHT; DIARRHEA; DOMESTIC PIG; DOSE RESPONSE; ENDOSCOPIC ECHOGRAPHY; FEMALE; HISTOLOGY; INJECTION; LABORATORY TEST; LACTATE DEHYDROGENASE BLOOD LEVEL; NECROSIS; NONHUMAN; PANCREAS; PARENCHYMA; PRIORITY JOURNAL; SAFETY;

EID: 47649114589     PISSN: 08159319     EISSN: 14401746     Source Type: Journal    
DOI: 10.1111/j.1440-1746.2007.04918.x     Document Type: Article

References (36)

1. Bassi C, Falconi M, Salvia R, Mascetta G, Molinari E, Pederzoli P. Management of complications after pancreaticoduodenectomy in a high volume center: results on 150 consecutive patients. Dig. Surg. 2001 18 : 453 7.
2. Burcharth F, Trillingsgaard J, Olsen SD, Moesgaard F, Federspiel B, Struckmann JR. Resection of cancer of the body and tail of the pancreas. Hepatogastroenterology 2003 50 : 563 6.
3. Paulino AC, Latona C. Unresectable adenocarcinoma of the pancreas: patterns of failure and treatment results. Cancer Invest. 2000 18 : 309 13.
4. Burris HA, Moore MJ, Andersen J et al. Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: a randomized trial. J. Clin. Oncol. 1997 15 : 2403 13.
5. Rothenberg ML, Moore MJ, Cripps MC et al. A phase II trial of gemcitabine in patients with 5-FU refractory pancreas cancer. Ann. Oncol. 1996 7 : 347 53.
6. Dobelbowwer RR, Borgelt BB, Suntharalingam N et al. Pancreatic carcinoma treated with high-dose, small-volume irradiation. Cancer 1978 41 : 1087 92.
7. Moertel CG, Frytak S, Hahn RG et al. Therapy of locally unresectable pancreatic carcinoma. A randomized comparison of high dose (6000 Rads) radiation alone, moderate dose radiation (4000 Rads + 5-fluorouracil), and high dose radiation +5-fluorouracil. The Gastrointestinal Tumor Study. Cancer 1981 48 : 1705 10.
8. Sindelar WF, Kinsella TJ. Studies of Intraoperative radiotherapy in carcinoma of the pancreas. Ann. Oncol. 1999 10 (Suppl. 4 226 30.
9. Alfieri S, Morganti AG, Giorgio AD et al. Improved survival and local control after Intraoperative radiation therapy and postoperative radiotherapy. Arch. Surg. 2001 136 : 343 7.
10. Homma H, Doi T, Mezawa S et al. A novel arterial infusion chemotherapy for the treatment of patients with advanced pancreatic carcinoma after vascular supply distribution via superselective embolization. Cancer 2000 15 : 303 13.
11. Chang KJ, Nguyen P, Erickson RA, Durbin TE, Katz KD. The clinical utility of endoscopic ultrasound-guided fine-needle aspiration in the diagnosis and staging of pancreatic carcinoma. Gastrointest. Endosc. 1997 45 : 387 93.
12. Gress FG, Hawes RH, Savides TJ, Ikenberry SO, Lehman GA. Endoscopic ultrasound-guided fine-needle aspiration biopsy using linear array and radial scanning endosonography. Gastrointest. Endosc. 1997 45 : 243 50.
13. Krinsky ML, Binmoeller KF. EUS-guided investigational therapy for pancreatic cancer. Gastrointest. Endosc. 2000 52 (6 Suppl. S35 8.
14. Gress F, Schmitt C, Sherman S, Ciaccia D, Ikenberry S, Lehman G. Endoscopic ultrasound-guided celiac plexus block for managing abdominal pain associated with chronic pancreatitis: a prospective single center experience. Am. J. Gastroenterol. 2001 96 : 409 16.
15. Gan SI, Thompson CC, Lauwers GY, Bounds BC, Brugge WR. Ethanol lavage of pancreatic cystic lesions: initial pilot study. Gastrointest. Endosc. 2005 61 : 746 52.
16. Etzkorn KP, DeGuzman LJ, Holderman WH et al. Endoscopic drainage of pancreatic pseudocysts: patient selection and evaluation of the outcome by endoscopic ultrasonography. Endoscopy 1995 27 : 329 33.
17. Giovannini M, Pesenti C, Rolland AL, Moutardier V, Delpero JR. Endoscopic ultrasound-guided drainage of pancreatic pseudocysts or pancreatic abscesses using a therapeutic echo endoscope. Endoscopy 2001 33 : 473 7.
18. Mortensen MB. The role of gastrointestinal endosonography in diagnostic and therapeutic interventional procedures. Eur. J. Ultrasound 1999 10 : 93 104.
19. Giovannini M, Moutardier V, Pesenti C, Bories E, Lelong B, Delpero JR. Endoscopic ultrasound-guided bilioduodenal anastomosis: a new technique for biliary drainage. Endoscopy 2001 33 : 898 900.
20. Chang KJ, Nguyen PT, Thompson JA et al. Phase I clinical trial of allogeneic mixed lymphocyte culture (cytoimplant) delivered by endoscopic ultrasound-guided fine-needle injection in patients with advanced pancreatic carcinoma. Cancer 2000 88 : 1325 35.
21. Hecht JR, Bedford R, Abbruzzese JL et al. A phase I/II trial of intratumoral endoscopic ultrasound injection of ONYX-015 with intravenous gemcitabine in unresectable pancreatic carcinoma. Clin. Cancer Res. 2003 9 : 555 61.
22. Goldberg SN, Mallery S, Gazelle GS, Brugge WR. EUS-guided radiofrequency ablation in the pancreas: results in a porcine model. Gastrointest. Endosc. 1999 50 : 392 401.
23. Chan HH, Nishioka NS, Mino M et al. EUS-guided photodynamic therapy of the pancreas: a pilot study. Gastrointest. Endosc. 2004 59 : 95 9.
24. Aslanian H, Salem RR, Marginean C et al. EUS-guided ethanol injection of normal porcine pancreas: a pilot study. Gastrointest. Endosc. 2005 62 : 723 7.
25. Vehmas T, Taari K, Kivisaari L, Laurila P, Taavitsainen M. Intra- and peri-hepatic effects of ethanol injections in the pig liver. Scand. J. Gastroenterol. 1993 28 : 791 4.
26. Livraghi T. Percutaneous ethanol injection in the treatment of hepatocellular carcinoma in cirrhosis. Hepatogastroenterology 2001 48 : 20 4.
27. Giovannini M, Seitz JF. Ultrasound-guided percutaneous alcohol injection of small liver metastases. Results in 40 patients. Cancer 1994 73 : 294 7.
28. Lee MJ, Mueller PR, Dawson SL et al. Percutaneous ethanol injection for the treatment of hepatic tumors: indications, mechanism of action, technique, and efficacy. Am. J. Roentgenol. 1995 164 : 215 20.
29. Kim JH, Lee HK, Lee JH, Ahn IM, Choi CG. Efficacy of sonographically guided percutaneous ethanol injection for treatment of thyroid cysts versus solid thyroid nodules. Am. J. Roentgenol. 2003 180 : 1723 6.
30. Chiang PH, Chuang YC, Huang CC, Chiang CP. Pilot study of transperineal injection of dehydrated ethanol in the treatment of prostatic obstruction. Urology 2003 61 : 797 801.
31. Gunter E, Lingenfelser T, Eitelbach F, Muller H, Ell C. EUS-guided ethanol injection for treatment of a GI stromal tumor. Gastrointest. Endosc. 2003 57 : 113 15.
32. Merkle EM, Haaga JR, Duerk JL, Jacobs GH, Brambs HJ, Lewin JS. MR imaging-guided radio-frequency thermal ablation in the pancreas in a porcine model with a modified clinical C-arm system. Radiology 1999 213 : 461 7.
33. Fosh BG, Finch JG, Anthony AA, Texler M, Maddern GJ. Electrolytic ablation of the rat pancreas: a feasibility trial. BMC Gastroenterol. 2001 1 : 9.
34. Livraghi T, Goldberg SN, Lazzaroni S et al. Small hepatocellular carcinoma: treatment with radio-frequency ablation versus ethanol injection. Radiology 1999 210 : 655 61.
35. Lin SM, Lin CJ, Lin CC, Hsu CW, Chen YC. Randomised controlled trial comparing percutaneous radiofrequency thermal ablation, percutaneous ethanol injection, and percutaneous acetic acid injection to treat hepatocellular carcinoma of 3 cm or less. Gut 2005 54 : 1151 6.
36. Ikeda M, Okada S, Ueno H et al. Radiofrequency ablation and percutaneous ethanol injection in patients with small hepatocellular carcinoma: a comparative study. Jpn J. Clin. Oncol. 2001 31 : 322 6.