Estradiol and neuropeptide Y (intra-lateral septal) reduce anxiety-like behavior in two animal models of anxiety

Peptides

Volumn 29, Issue 8, 2008, Pages 1396-1403

  Olivera Lopez, Jorge I ^b,c   Molina Hernández, Miguel ^a   Tellez Alcántara, N Patricia ^a   Jaramillo, M Teresa ^b  

^a UNIVERSIDAD VERACRUZANA   (Mexico)

^b UNIVERSIDAD AUTÓNOMA METROPOLITANA   (Mexico)

^c DEPARTAMENTO DE SISTEMAS BIOLÓGICOS   (Mexico)

Author keywords

Conflict behavior; Elevated plus maze; Estradiol; Lateral septal nuclei; Neuropeptide Y

Indexed keywords

ESTRADIOL; NEUROPEPTIDE Y;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANXIETY DISORDER; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; DRUG POTENTIATION; LOCOMOTION; MAZE TEST; NEUROTRANSMISSION; NONHUMAN; PRIORITY JOURNAL; RAT; TASK PERFORMANCE; TRANQUILIZING ACTIVITY;

ANIMALS; ANTI-ANXIETY AGENTS; ANXIETY DISORDERS; BEHAVIOR, ANIMAL; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ESTRADIOL; FEMALE; MOTOR ACTIVITY; NEUROPEPTIDE Y; OVARIECTOMY; RATS; RATS, WISTAR;

ANIMALIA; RATTUS NORVEGICUS;

EID: 47649083540     PISSN: 01969781     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.peptides.2008.04.002     Document Type: Article

References (62)

1. Bitran D., Shiekh M., and Mcleod M. Anxiolytic effect of progesterone is mediated by the neurosteroid allopregnanolone at brain GABA-A receptors. J Neuroendocrinol 7 (1995) 171-177
2. Bitran D., and Dowd J.A. Ovarian steroids modify the behavioral and neurochemical responses of the central benzodiazepine receptor. Psychopharmacology 125 (1996) 65-73
3. Bodo C., and Rissman E. New roles for estrogen receptor β in behavior and neuroendocrinology. Front Neuroendocrinol 27 (2006) 217-232
4. Britton K.T., Southerland S., Uden E., Kirby D., Rivier J., and Koob G. Anxiolytic activity of NPY receptor agonists in the conflict test. Psychopharmacology 132 (1997) 6-13
5. Britton K.T., Akwa Y., Spina M.G., and Koob G. Neuropeptide Y blocks anxiogenic-like behavioral action of corticotropin-releasing factor in an operant conflict test and elevated plus-maze. Peptides 21 (2000) 37-44
6. Charney D.S. Psychobiological mechanisms of resilience and vulnerability: implications for successful adaptation to extreme stress. Am J Psychiatr 161 (2004) 195-216
7. Contreras C.M., Molina M., Savedra M., and Martinez L. Lateral septal neuronal firing rate increases during proestrus-estrus in the rat. Physiol Behav 68 (2000) 279-284
8. Díaz-Véliz G., Urresta F., Dussaubat N., and Mora S. Progesterone effects on the acquisition of conditioned avoidance responses and other motoric behaviors in intact and ovariectomized rats. Psychoneuroendocrinology 19 (1994) 387-394
9. Eva C., Serra M., Mele P., Panzica G., and Oberto A. Physiology and gene regulation of the brain NPY Y1 receptor. Front Neuroendocrinol 27 (2006) 308-339
10. Fernández-Guasti A., and Picazo O. Changes in burying behavior during the estrous cycle: effect of estrogen and progesterone. Psychoneuroendocrinology 17 (1992) 681-689
11. Freeman M.E. The ovarian cycle of the rat. In: Knobil E., and de Neil J. (Eds). The physiology of reproduction (1988), Raven, New York 1893-1928
12. Freund T.F., and Buzsaki G. Interneurons of the hippocampus. Hippocampus 6 (1996) 347-470
13. Gilpin N.W., Stewart R.B., Elder R.L., Kho Y., Murphy J.M., Li T., et al. Sedative and motor-impairing effects of neuropeptide Y and ethanol in selectively bred P and NP rats. Pharmacol Biochem Behav 78 (2004) 65-73
14. Handley S.L., and McBlane J.W. An assessment of the elevated X maze for studying anxiety and anxiety-modulating drugs. J Pharmacol Toxicol Methods 29 (1993) 129-135
15. Hascoët M., Bourin M., Todd K.G., and Couetoux du Tertre A. Anti-conflict effect of 5HT-1A agonists in rats: a new model for evaluating anxiolytic-like activity. J Psychopharmacology 8 (1994) 227-237
16. Heilig M., Söderpalm B., Engel J.A., and Widerlöv E. Centrally administered neuropeptide Y (NPY) produces anxiolytic-like effects in animal anxiety models. Psychopharmacology 98 (1989) 524-529
17. Heilig M., McLeod S., Brot M., Heinrichs S.C., Menzaghi F., Koob G.F., et al. Anxiolytic-like action of neuropeptide Y: mediation by Y1 receptors in amygdala, and dissociation from food intake effects. Neuropsychopharmacology 8 (1993) 357-363
18. Heilig M. The NPY system in stress, anxiety and depression. Neuropeptides 38 (2004) 213-224
19. Hogg S. A review of the validity and variability of the elevated plus-maze as an animal model of anxiety. Pharmacol Biochem Behav 54 (1996) 21-30
20. Hurwitz H.M., and Davis H. Depriving rats of food: a reappraisal of two techniques. J Exp Anal Behav 40 (1983) 211-213
21. Jakab R.L., and Leranth C. Septum. In: Paxinos G. (Ed). The Rat Nervous System (1995), Academic Press, San Diego 405-431
22. Kask A., Rago L., and Harro J. Anxiolytic-like effect of neuropeptide Y (NPY) and NPY13-36 microinjected into vicinity of locus coeruleus in rats. Brain Res 788 (1998) 345-348
23. Kask A., Lembit R., and Harro J. NPY Y1 receptors in the dorsal periaqueductal gray matter regulate anxiety in the social interaction test. NeuroReport 12 (1998) 2713-2717
24. Kask A., Nguyen H.P., Pabst R., and Hörsten S. Neuropeptide Y Y1 receptor-mediated anxiolysis in the dorsocaudal lateral septum: functional antagonism of corticotropin-releasing hormone-induced anxiety. Neuroscience 104 (2001) 799-806
25. Kask A., Harro J., Von Hörsten S., Redrobe J.P., Dumont Y., and Quirion R. The neurocircuitry and receptor subtypes mediating anxiolytic-like effects of neuropeptide Y. Neurosci Biobehav Rev 26 (2002) 259-283
26. Kokare D., Dandekar M., Chopde C., and Subhedar N. Interaction between neuropeptide Y and alpha-melanocyte stimulating hormone in amygdala regulates anxiety in rats. Brain Res 1043 (2005) 107-114
27. Koss W., Gehlert D., and Shekhar A. Different effects of subchronic doses of 17-β-estradiol in two ethologically based models of anxiety utilizing female rats. Horm Behav 46 (2004) 158-164
28. Kovács E., Szalay F., Rácz B., and Halasy K. Chronic fasting-induced changes of neuropeptide Y immunoreactivity in the lateral septum of intact and ovariectomized female rats. Brain Res 1153 (2007) 103-110
29. Leer M.N., Bradbury A., Maloney J.C., and Stewart C.N. Elevated shock threshold in sexually receptive female rats. Physiol Behav 42 (1988) 617-620
30. Marcondes F.K., Miguel K.J., Melo L.L., and Spadari-Bratfisch R.C. Estrous cycle influences the response of female rats in the elevated plus-maze test. Physiol Behav 74 (2001) 435-440
31. Massé F., Dhonnchadha B., Hascoët M., and Bourin M. Anxiolytic-like effect of 5HT-2 ligands and benzodiazepines co-administration: comparison of two animal models of anxiety (the four plate test and the elevated plus-maze). Behav Brain Res 177 (2007) 214-226
32. Menard J., and Treit D. Effects of centrally administered anxiolytic compounds in animal models of anxiety. Neurosci Biobehav Rev 23 (1999) 591-613
33. Migita K., Loewy A.D., Ramabhadran T., Krause J.E., and Waters S.M. Immunohistochemical localization of the neuropeptide Y Y1 receptor in rat central nervous system. Brain Res 889 (2001) 23-37
34. Millan M. The neurobiology and control of anxious states. Prog Neurobiol 70 (2003) 83-244
35. Mouihate A., Chen X., and Pittman Q.J. Interleukin-1β fever in rats: gender difference and estrous cycle influence. Am J Physiol 275 (1998) R1450-R1454
36. Molina-Hernández M., and Téllez-Alcántara P. Estrus variation in anticonflict effects of midazolam microinjected into septal nuclei in female Wistar rats. Pharmacol Biochem Behav 68 (2001) 531-537
37. Molina-Hernández M., Contreras C.M., and Téllez-Alcántara P. Diazepam increases the number of punished responses in a conflict-operant paradigm during late proestrus and estrus in the Wistar rat. Neuropsychobiology 43 (2001) 29-33
38. Molina-Hernández M., Perez J., and Olivera J. Female Wistar rats tested during late proestrus or during pregnancy and ovariectomized rats tested alter receiving progesterone or allopregnanolone displayed reduced conflict behavior. Prog Neuro-Psychopharmacol Biol Psychiatr 26 (2002) 839-844
39. Molina-Hernández M., Téllez-Alcántara P., Perez J., Olivera J., and Jaramillo T. Anti-conflict-like actions of intralateral septal infusions of allopregnanolone in Wistar rats. Pharmacol Biochem Behav 75 (2003) 397-404
40. Molina M., Olivera J., Téllez-Alcántara N.P., Perez-García J., and Jaramillo-Jaimes M.T. Estrus variation in anxiolytic-like effects of intra-lateral septal infusions of the neuropeptide Y in Wistar rats in two animal models of anxiety-like behavior. Peptides 27 (2006) 2722-2730
41. Munglani R., Hudspith M.J., and Hunt S.P. The therapeutic potential of neuropeptide Y. Analgesic, anxiolytic and antihypertensive. Drugs 52 (1996) 371-389
42. Nakamura N.H., and McEwen B.S. Changes in interneuronal phenotypes regulated by estradiol in the adult rat hippocampus: a potential role for neuropeptide Y. Neuroscience 136 (2005) 357-369
43. National Institutes of Health. Guide for the care and use of laboratory animals (1996), National Academy Press, Washington, DC
44. Obuchowicz E., Krysiak R., and Herman Z. Does neuropeptide Y (NPY) mediate the effects of psychotropic drugs?. Neurosci Biobehav Rev 28 (2004) 595-610
45. Pandaranandaka J., Poonyachoti S., and Kalandakanond S. Anxiolytic property of estrogen related to the changes of the monoamine levels in various brain regions of ovariectomized rats. Physiol Behav 87 (2006) 828-835
46. Panzica G.C., Aste N., Viglietti-Panzica C., and Ottinger M.A. Structural sex differences in the brain: influence of gonadal steroids and behavioral correlates. J Endocrinol Invest 18 (1995) 232-252
47. Paxinos G., and Watson C. The rat brain in stereotaxic coordinates (1982), Academic Press, New York
48. Pesold C., and Treit D. The septum and amygdala differentially mediate the anxiolytic effects of benzodiazepines. Brain Res 638 (1994) 295-301
49. Rainbow T.C., Parsons B., and McEwen B.S. Sex differences in rat brain oestrogen and progestin receptors. Nature 300 (1982) 648-941
50. Risold P.Y., and Swanson L.W. Chemoarchitecture of the rat lateral septal nucleus. Brain Res Rev 24 (1997) 91-113
51. Rodgers R.L., and Dalvi A. Anxiety, defense and the elevated plus-maze. Neurosci Biobehav Rev 21 (1997) 801-810
52. Rodriguez J.F., Howard J.L., Pollard G.T., and Hendricks S.E. Effect of ovarian hormones on conflict behaviour. Psychoneuroendocrinology 9 (1984) 293-300
53. Sajdyk T.J., Shekhar A., and Gehlert D.R. Interactions between NPY and CRF in the amygdala to regulate emotionality. Neuropeptides 38 (2004) 225-234
54. Sheehan T.P., Chambers R.A., and Russel D.S. Regulation of affect by the lateral septum: implications for neuropsychiatry. Brain Res Rev 46 (2004) 71-117
55. Shimizu H., Ohtani K., Kato Y., Tanaka Y., and Mori M. Estrogen increases hypothalamic neuropeptide Y (NPY) mRNA expression in ovariectomized obese rat. Neurosci Lett 204 (1996) 81-84
56. Simerly R.B., Chang C., Muramatsu M., and Swanson L.W. Distribution of androgen and estrogen receptor MRNA-containing cells in the rat brain: an in situ hybridization study. J Comp Neurol 294 (1990) 76-95
57. Thomas E., Yadin E., and Strickland C.E. Septal activity during classical conditioning: a regional comparison. Brain Res 547 (1991) 303-308
58. Tritos N.A., Segal G., Vezeridis P., and Maratos E. Estradiol-induced anorexia is independent of leptin and melanin-concentrating hormone. Obesity Res 12 (2004) 716-724
59. Walf A., and Frye C. Antianxiety and antidepressive behavior produced by physiological estradiol regimen may be modulated by hypothalamic-pituitary-adrenal axis modulation. Neuropsychopharmacology 30 (2005) 1288-1301
60. Walf A., and Frye C. ERβ-selective estrogen receptor modulators produce antianxiety behavior when administered systemically to ovariectomized rats. Neuropsychopharmacology 30 (2005) 1598-1609
61. Yadin E., and Thomas E. Septal correlates of conditioned inhibition and excitation in rats. J Comp Physiol Psychol 95 (1981) 331-340
62. Yadin E., Thomas E., Grishka H.L., and Strickland C.E. The role of the lateral septum in anxiolysis. Physiol Behav 53 (1993) 1077-1083