메뉴 건너뛰기




Volumn 389, Issue 6, 2008, Pages 773-780

An AKT activity threshold regulates androgen-dependent and androgen-independent PSA expression in prostate cancer cell lines

Author keywords

AKT activity; Androgen receptor; Androgen independent; Prostate cancer; Prostate specific antigen

Indexed keywords

ANDROGEN; EPIDERMAL GROWTH FACTOR; PROSTATE SPECIFIC ANTIGEN; PROTEIN KINASE B;

EID: 47549118308     PISSN: 14316730     EISSN: 14374315     Source Type: Journal    
DOI: 10.1515/BC.2008.072     Document Type: Conference Paper
Times cited : (17)

References (37)
  • 1
    • 0034711307 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase function is required for transforming growth factor β-mediated epithelial to mesenchymal transition and cell migration
    • Bakin, A.V., Tomlinson, A.K., Bhowmick, N.A., Moses, H.L., and Arteaga, C.L. (2000). Phosphatidylinositol 3-kinase function is required for transforming growth factor β-mediated epithelial to mesenchymal transition and cell migration. J. Biol. Chem. 275, 36803-36810.
    • (2000) J. Biol. Chem , vol.275 , pp. 36803-36810
    • Bakin, A.V.1    Tomlinson, A.K.2    Bhowmick, N.A.3    Moses, H.L.4    Arteaga, C.L.5
  • 2
    • 0037447330 scopus 로고    scopus 로고
    • Constitutive activation of the Ras/mitogen-activated protein kinase signaling pathway promotes androgen hypersensitivity in LNCaP prostate cancer cells
    • Bakin, R.E., Gioeli, D., Sikes, R.A., Bissonette, E.A., and Weber, M.J. (2003). Constitutive activation of the Ras/mitogen-activated protein kinase signaling pathway promotes androgen hypersensitivity in LNCaP prostate cancer cells. Cancer Res. 63, 1981-1989.
    • (2003) Cancer Res , vol.63 , pp. 1981-1989
    • Bakin, R.E.1    Gioeli, D.2    Sikes, R.A.3    Bissonette, E.A.4    Weber, M.J.5
  • 3
    • 0037440205 scopus 로고    scopus 로고
    • Biology of prostate-specific antigen
    • Balk, S.P., Ko, Y.J., and Bubley, G.J. (2003). Biology of prostate-specific antigen. J. Clin. Oncol. 21, 383-391.
    • (2003) J. Clin. Oncol , vol.21 , pp. 383-391
    • Balk, S.P.1    Ko, Y.J.2    Bubley, G.J.3
  • 4
    • 4544335595 scopus 로고    scopus 로고
    • EGF receptor (EGFR) signaling promoting invasion is disrupted in androgen-sensitive prostate cancer cells by an interaction between EGFR and androgen receptor (AR)
    • Bonaccorsi, L., Carloni, V., Muratori, M., Formigli, L., Zecchi, S., Forti, G., and Baldi, E. (2004a). EGF receptor (EGFR) signaling promoting invasion is disrupted in androgen-sensitive prostate cancer cells by an interaction between EGFR and androgen receptor (AR). Int. J. Cancer 112, 78-86.
    • (2004) Int. J. Cancer , vol.112 , pp. 78-86
    • Bonaccorsi, L.1    Carloni, V.2    Muratori, M.3    Formigli, L.4    Zecchi, S.5    Forti, G.6    Baldi, E.7
  • 6
    • 0034668172 scopus 로고    scopus 로고
    • Induction and regulation of epithelial-mesenchymal transitions
    • Boyer, B., Valles, A.M., and Edme, N. (2000). Induction and regulation of epithelial-mesenchymal transitions. Biochem. Pharmacol. 60, 1091-1099.
    • (2000) Biochem. Pharmacol , vol.60 , pp. 1091-1099
    • Boyer, B.1    Valles, A.M.2    Edme, N.3
  • 7
    • 0029986012 scopus 로고    scopus 로고
    • Ultrasensitive detection of prostate-specific antigen by a time-resolved immunofluorometric assay and the Immulite immunochemiluminescent third-generation assay: Potential applications in prostate and breast cancers
    • Ferguson, R.A., Yu, H., Kalyvas, M., Zammit, S., and Diamandis, E.P. (1996). Ultrasensitive detection of prostate-specific antigen by a time-resolved immunofluorometric assay and the Immulite immunochemiluminescent third-generation assay: potential applications in prostate and breast cancers. Clin. Chem. 42, 675-684.
    • (1996) Clin. Chem , vol.42 , pp. 675-684
    • Ferguson, R.A.1    Yu, H.2    Kalyvas, M.3    Zammit, S.4    Diamandis, E.P.5
  • 8
    • 33749254070 scopus 로고    scopus 로고
    • Combinatorial activities of Akt and B-Raf/Erk signaling in a mouse model of androgen-independent prostate cancer
    • Gao, H., Ouyang, X., Banach-Petrosky, W.A., Gerald, W.L., Shen, M.M., and bate-Shen, C. (2006). Combinatorial activities of Akt and B-Raf/Erk signaling in a mouse model of androgen-independent prostate cancer. Proc. Natl. Acad. Sci. USA 103, 14477-14482.
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 14477-14482
    • Gao, H.1    Ouyang, X.2    Banach-Petrosky, W.A.3    Gerald, W.L.4    Shen, M.M.5    bate-Shen, C.6
  • 9
    • 0030347316 scopus 로고    scopus 로고
    • Androgen receptor mutations in prostate cancer
    • Gelmann, E.P. (1996). Androgen receptor mutations in prostate cancer. Cancer Treat. Res. 87, 285-302.
    • (1996) Cancer Treat. Res , vol.87 , pp. 285-302
    • Gelmann, E.P.1
  • 11
    • 0037728809 scopus 로고    scopus 로고
    • The protein kinase Akt induces epithelial mesenchymal transition and promotes enhanced motility and invasiveness of squamous cell carcinoma lines
    • Grille, S.J., Bellacosa, A., Upson, J., Klein-Szanto, A.J., van Roy, F., Lee-Kwon, W., Donowitz, M., Tsichlis, P.N., and Larue, L. (2003). The protein kinase Akt induces epithelial mesenchymal transition and promotes enhanced motility and invasiveness of squamous cell carcinoma lines. Cancer Res. 63, 2172-2178.
    • (2003) Cancer Res , vol.63 , pp. 2172-2178
    • Grille, S.J.1    Bellacosa, A.2    Upson, J.3    Klein-Szanto, A.J.4    van Roy, F.5    Lee-Kwon, W.6    Donowitz, M.7    Tsichlis, P.N.8    Larue, L.9
  • 12
    • 0035930133 scopus 로고    scopus 로고
    • Androgen receptor signaling in androgen-refractory prostate cancer
    • Grossmann, M.E., Huang, H., and Tindall, D.J. (2001). Androgen receptor signaling in androgen-refractory prostate cancer. J. Natl. Cancer Inst. 93, 1687-1697.
    • (2001) J. Natl. Cancer Inst , vol.93 , pp. 1687-1697
    • Grossmann, M.E.1    Huang, H.2    Tindall, D.J.3
  • 13
    • 32644486084 scopus 로고    scopus 로고
    • EGFR signaling pathway negatively regulates PSA expression and secretion via the PI3K-Akt pathway in LNCaP prostate cancer cells
    • Hakariya, T., Shida, Y., Sakai, H., Kanetake, H., and Igawa, T. (2006). EGFR signaling pathway negatively regulates PSA expression and secretion via the PI3K-Akt pathway in LNCaP prostate cancer cells. Biochem. Biophys. Res. Commun. 342, 92-100.
    • (2006) Biochem. Biophys. Res. Commun , vol.342 , pp. 92-100
    • Hakariya, T.1    Shida, Y.2    Sakai, H.3    Kanetake, H.4    Igawa, T.5
  • 14
    • 0031024251 scopus 로고    scopus 로고
    • Androgen-dependent cell cycle arrest and apoptotic death in PC-3 prostatic cell cultures expressing a full-length human androgen receptor
    • Heisler, L.E., Evangelou, A., Lew, A.M., Trachtenberg, J., Elsholtz, H.P., and Brown, T.J. (1997). Androgen-dependent cell cycle arrest and apoptotic death in PC-3 prostatic cell cultures expressing a full-length human androgen receptor. Mol. Cell. Endocrinol. 126, 59-73.
    • (1997) Mol. Cell. Endocrinol , vol.126 , pp. 59-73
    • Heisler, L.E.1    Evangelou, A.2    Lew, A.M.3    Trachtenberg, J.4    Elsholtz, H.P.5    Brown, T.J.6
  • 15
    • 4143148652 scopus 로고    scopus 로고
    • Prostate-specific antigen: A review of the validation of the most commonly used cancer biomarker
    • Hernandez, J. and Thompson, I.M. (2004). Prostate-specific antigen: a review of the validation of the most commonly used cancer biomarker. Cancer 101, 894-904.
    • (2004) Cancer , vol.101 , pp. 894-904
    • Hernandez, J.1    Thompson, I.M.2
  • 16
    • 33745980188 scopus 로고    scopus 로고
    • Effect of keratinocyte growth factor on cell viability in primary cultured human prostate cancer stromal cells
    • Huang, Y.W., Wang, L.S., Chang, H.L., Ye, W., Shu, S., Sugimoto, Y., and Lin, Y.C. (2006). Effect of keratinocyte growth factor on cell viability in primary cultured human prostate cancer stromal cells. J. Steroid Biochem. Mol. Biol. 100, 24-33.
    • (2006) J. Steroid Biochem. Mol. Biol , vol.100 , pp. 24-33
    • Huang, Y.W.1    Wang, L.S.2    Chang, H.L.3    Ye, W.4    Shu, S.5    Sugimoto, Y.6    Lin, Y.C.7
  • 18
    • 16544369846 scopus 로고    scopus 로고
    • Prostate specific antigen gene regulation by androgen receptor
    • Kim, J. and Coetzee, G.A. (2004). Prostate specific antigen gene regulation by androgen receptor. J. Cell. Biochem. 93, 233-241.
    • (2004) J. Cell. Biochem , vol.93 , pp. 233-241
    • Kim, J.1    Coetzee, G.A.2
  • 19
    • 27844461512 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition in development and cancer: Role of phosphatidylinositol 39 kinase/AKT pathways
    • Larue, L. and Bellacosa, A. (2005). Epithelial-mesenchymal transition in development and cancer: role of phosphatidylinositol 39 kinase/AKT pathways. Oncogene 24, 7443-7454.
    • (2005) Oncogene , vol.24 , pp. 7443-7454
    • Larue, L.1    Bellacosa, A.2
  • 20
    • 33645302628 scopus 로고    scopus 로고
    • The epithelial-mesenchymal transition: New insights in signaling, development, and disease
    • Lee, J.M., Dedhar, S., Kalluri, R., and Thompson, E.W. (2006). The epithelial-mesenchymal transition: new insights in signaling, development, and disease. J. Cell Biol. 172, 973-981.
    • (2006) J. Cell Biol , vol.172 , pp. 973-981
    • Lee, J.M.1    Dedhar, S.2    Kalluri, R.3    Thompson, E.W.4
  • 21
  • 23
    • 0347696003 scopus 로고    scopus 로고
    • Suppression versus induction of androgen receptor functions by the phosphatidylinositol 3-kinase/Akt pathway in prostate cancer LNCaP cells with different passage numbers
    • Lin, H.K., Hu, Y.C., Yang, L., Altuwaijri, S., Chen, Y.T., Kang, H.Y., and Chang, C. (2003). Suppression versus induction of androgen receptor functions by the phosphatidylinositol 3-kinase/Akt pathway in prostate cancer LNCaP cells with different passage numbers. J. Biol. Chem. 278, 50902-50907.
    • (2003) J. Biol. Chem , vol.278 , pp. 50902-50907
    • Lin, H.K.1    Hu, Y.C.2    Yang, L.3    Altuwaijri, S.4    Chen, Y.T.5    Kang, H.Y.6    Chang, C.7
  • 24
    • 0035912833 scopus 로고    scopus 로고
    • Akt suppresses androgen-induced apoptosis by phosphorylating and inhibiting androgen receptor
    • Lin, H.K., Yeh, S., Kang, H.Y., and Chang, C. (2001). Akt suppresses androgen-induced apoptosis by phosphorylating and inhibiting androgen receptor. Proc. Natl. Acad. Sci. USA 98, 7200-7205.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 7200-7205
    • Lin, H.K.1    Yeh, S.2    Kang, H.Y.3    Chang, C.4
  • 26
    • 33645690200 scopus 로고    scopus 로고
    • Mechanisms underlying the development of androgen-independent prostate cancer
    • Pienta, K.J. and Bradley, D. (2006). Mechanisms underlying the development of androgen-independent prostate cancer. Clin. Cancer Res. 12, 1665-1671.
    • (2006) Clin. Cancer Res , vol.12 , pp. 1665-1671
    • Pienta, K.J.1    Bradley, D.2
  • 27
    • 0032972785 scopus 로고    scopus 로고
    • Tissue PSA is the best predicting variable for the outcome of endocrine treatment of prostatic carcinoma
    • Pousette, A., Grande, M., Carlstrom, K., and Stege, R. (1999). Tissue PSA is the best predicting variable for the outcome of endocrine treatment of prostatic carcinoma. Scand. J. Clin. Lab. Invest. Suppl. 229, 27-32.
    • (1999) Scand. J. Clin. Lab. Invest. Suppl , vol.229 , pp. 27-32
    • Pousette, A.1    Grande, M.2    Carlstrom, K.3    Stege, R.4
  • 29
    • 33646940750 scopus 로고    scopus 로고
    • Molecular biology of prostate-cancer pathogenesis
    • Shand, R.L. and Gelmann, E.P. (2006). Molecular biology of prostate-cancer pathogenesis. Curr. Opin. Urol. 16, 123-131.
    • (2006) Curr. Opin. Urol , vol.16 , pp. 123-131
    • Shand, R.L.1    Gelmann, E.P.2
  • 30
    • 0037599536 scopus 로고    scopus 로고
    • Androgen receptor involvement in the progression of prostate cancer
    • Suzuki, H., Ueda, T., Ichikawa, T., and Ito, H. (2003). Androgen receptor involvement in the progression of prostate cancer. Endocr. Relat. Cancer 10, 209-216.
    • (2003) Endocr. Relat. Cancer , vol.10 , pp. 209-216
    • Suzuki, H.1    Ueda, T.2    Ichikawa, T.3    Ito, H.4
  • 31
    • 3843069106 scopus 로고    scopus 로고
    • Androgen receptor: A key molecule in the progression of prostate cancer to hormone independence
    • Taplin, M.E. and Balk, S.P. (2004). Androgen receptor: a key molecule in the progression of prostate cancer to hormone independence. J. Cell. Biochem. 91, 483-490.
    • (2004) J. Cell. Biochem , vol.91 , pp. 483-490
    • Taplin, M.E.1    Balk, S.P.2
  • 33
    • 0031079544 scopus 로고    scopus 로고
    • Androgen-regulated gene expression in prostate cancer
    • Trapman, J. and Cleutjens, K.B. (1997). Androgen-regulated gene expression in prostate cancer. Semin. Cancer Biol. 8, 29-36.
    • (1997) Semin. Cancer Biol , vol.8 , pp. 29-36
    • Trapman, J.1    Cleutjens, K.B.2
  • 35
    • 0035165102 scopus 로고    scopus 로고
    • HER2 overexpression and cancer targeting
    • Wang, S.C. and Hung, M.C. (2001). HER2 overexpression and cancer targeting. Semin. Oncol. 28, 115-124.
    • (2001) Semin. Oncol , vol.28 , pp. 115-124
    • Wang, S.C.1    Hung, M.C.2
  • 36
    • 33646739524 scopus 로고    scopus 로고
    • Progression of prostate cancer by synergy of AKT with genotropic and nongenotropic actions of the androgen receptor
    • Xin, L., Teitell, M.A., Lawson, D.A., Kwon, A., Mellinghoff, I.K., and Witte, O.N. (2006). Progression of prostate cancer by synergy of AKT with genotropic and nongenotropic actions of the androgen receptor. Proc. Natl. Acad. Sci. USA 103, 7789-7794.
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 7789-7794
    • Xin, L.1    Teitell, M.A.2    Lawson, D.A.3    Kwon, A.4    Mellinghoff, I.K.5    Witte, O.N.6
  • 37
    • 0037564511 scopus 로고    scopus 로고
    • Interleukin-6 differentially regulates androgen receptor transactivation via PI3KAkt, STAT3, and MAPK, three distinct signal pathways in prostate cancer cells
    • Yang, L., Wang, L., Lin, H.K., Kan, P.Y., Xie, S., Tsai, M.Y., Wang, P.H., Chen, Y.T., and Chang, C. (2003). Interleukin-6 differentially regulates androgen receptor transactivation via PI3KAkt, STAT3, and MAPK, three distinct signal pathways in prostate cancer cells. Biochem. Biophys. Res. Commun. 305, 462-469.
    • (2003) Biochem. Biophys. Res. Commun , vol.305 , pp. 462-469
    • Yang, L.1    Wang, L.2    Lin, H.K.3    Kan, P.Y.4    Xie, S.5    Tsai, M.Y.6    Wang, P.H.7    Chen, Y.T.8    Chang, C.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.