메뉴 건너뛰기




Volumn 6, Issue 6, 2008, Pages 536-564

Cancer- and chemotherapy-induced anemia

(21)  Rodgers III, George M a   Becker, Pamela Sue b   Bennett, Charles L c   Cella, David c   Chanan Khan, Asher d   Chesney, Carolyn e   Cleeland, Charles f   Coccia, Peter F g   Djulbegovic, Benjamin h   Garst, Jennifer L i   Gilreath, Jeffrey A a   Kraut, Eric H j   Lin, Weei Chin k   Matulonis, Ursula l   Millenson, Michael m   Reinke, Denise n   Rosenthal, Joseph o   Sabbatini, Paul p   Schwartz, Rowena N q   Stein, Richard S r   more..


Author keywords

Anemia; Chemotherapy; Darbepoetin; Epoetin; Erythropoietin; Ferric gluconate; Heme iron polypeptide; Hemoglobin; Iron dextran; Iron sucrose; NCCN clinical practice guidelines; Quality of life; Serum ferritin

Indexed keywords

ANTINEOPLASTIC AGENT; CARBOPLATIN; CISPLATIN; CYCLOPHOSPHAMIDE; DOCETAXEL; DOXORUBICIN; ERYTHROPOIETIN; ETOPOSIDE; FERRIC GLUCONATE; FERRIC HYDROXIDE SUCROSE; FLUOROURACIL; HEMOGLOBIN; IFOSFAMIDE; IRON; IRON DEXTRAN; NAVELBINE; NOVEL ERYTHROPOIESIS STIMULATING PROTEIN; PACLITAXEL; PLACEBO; PREDNISONE; RECOMBINANT ERYTHROPOIETIN; TOPOTECAN; VINCRISTINE;

EID: 47549115609     PISSN: 15401405     EISSN: 15401413     Source Type: Journal    
DOI: 10.6004/jnccn.2008.0042     Document Type: Review
Times cited : (34)

References (91)
  • 1
    • 33846687689 scopus 로고    scopus 로고
    • Anemia in patients with cancer: Incidence, causes, impact, management, and use of treatment guidelines and protocols
    • quiz S28-30
    • Schwartz RN. Anemia in patients with cancer: incidence, causes, impact, management, and use of treatment guidelines and protocols. Am J Health Syst Pharm 2007;64:S5-13; quiz S28-30.
    • (2007) Am J Health Syst Pharm , vol.64
    • Schwartz, R.N.1
  • 2
    • 41949129089 scopus 로고    scopus 로고
    • Is anemia of cancer different from chemotherapy-induced anemia?
    • Steensma DP. Is anemia of cancer different from chemotherapy-induced anemia? J Clin Oncol 2008;26:1022-1024.
    • (2008) J Clin Oncol , vol.26 , pp. 1022-1024
    • Steensma, D.P.1
  • 3
    • 84891931168 scopus 로고    scopus 로고
    • A systematic review and economic evaluation of epoetin alpha, epoetin beta and darbepoetin alpha in anaemia associated with cancer, especially that attributable to cancer treatment
    • iii-iv
    • Wilson J, Yao GL, Raftery J, et al. A systematic review and economic evaluation of epoetin alpha, epoetin beta and darbepoetin alpha in anaemia associated with cancer, especially that attributable to cancer treatment. Health Technol Assess 2007;11:1-202, iii-iv.
    • (2007) Health Technol Assess , vol.11 , pp. 1-202
    • Wilson, J.1    Yao, G.L.2    Raftery, J.3
  • 4
    • 0031741680 scopus 로고    scopus 로고
    • Frequency and significance of anemia in non-Hodgkin's lymphoma patients
    • Moullet I, Salles G, Ketterer N, et al. Frequency and significance of anemia in non-Hodgkin's lymphoma patients. Ann Oncol 1998;9:1109-1115.
    • (1998) Ann Oncol , vol.9 , pp. 1109-1115
    • Moullet, I.1    Salles, G.2    Ketterer, N.3
  • 5
    • 5344263788 scopus 로고    scopus 로고
    • The European Cancer Anaemia Survey (ECAS): A large, multinational, prospective survey defining the prevalence, incidence, and treatment of anaemia in cancer patients
    • Ludwig H, Van Belle S, Barrett-Lee P, et al. The European Cancer Anaemia Survey (ECAS): a large, multinational, prospective survey defining the prevalence, incidence, and treatment of anaemia in cancer patients. Eur J Cancer 2004;40:2293-2306.
    • (2004) Eur J Cancer , vol.40 , pp. 2293-2306
    • Ludwig, H.1    Van Belle, S.2    Barrett-Lee, P.3
  • 6
    • 0031785826 scopus 로고    scopus 로고
    • Quality-of-life benefit in chemotherapy patients treated with epoetin alfa is independent of disease response or tumor type: Results from a prospective community oncology study. Procrit Study Group
    • Demetri GD, Kris M, Wade J, et al. Quality-of-life benefit in chemotherapy patients treated with epoetin alfa is independent of disease response or tumor type: results from a prospective community oncology study. Procrit Study Group. J Clin Oncol 1998;16:3412-3425.
    • (1998) J Clin Oncol , vol.16 , pp. 3412-3425
    • Demetri, G.D.1    Kris, M.2    Wade, J.3
  • 7
    • 0031044609 scopus 로고    scopus 로고
    • Impact of therapy with epoetin alfa on clinical outcomes in patients with nonmyeloid malignancies during cancer chemotherapy in community oncology practice. Procrit Study Group
    • Glaspy J, Bukowski R, Steinberg D, et al. Impact of therapy with epoetin alfa on clinical outcomes in patients with nonmyeloid malignancies during cancer chemotherapy in community oncology practice. Procrit Study Group. J Clin Oncol 1997;15:1218-1234.
    • (1997) J Clin Oncol , vol.15 , pp. 1218-1234
    • Glaspy, J.1    Bukowski, R.2    Steinberg, D.3
  • 8
    • 84921622949 scopus 로고    scopus 로고
    • Transfusion thresholds and other strategies for guiding allogeneic red blood cell transfusion
    • CD002042
    • Hill SR, Carless PA, Henry DA, et al. Transfusion thresholds and other strategies for guiding allogeneic red blood cell transfusion. Cochrane Database Syst Rev 2002:CD002042.
    • (2002) Cochrane Database Syst Rev
    • Hill, S.R.1    Carless, P.A.2    Henry, D.A.3
  • 9
    • 47549112567 scopus 로고    scopus 로고
    • Different threshold levels for red blood cell transfusions in patients with haematological malignancy (protocol)
    • Pawson R, Brunskill S, Murphy MF, et al. Different threshold levels for red blood cell transfusions in patients with haematological malignancy (protocol). The Cochrane Library 2008:10.
    • (2008) The Cochrane Library , pp. 10
    • Pawson, R.1    Brunskill, S.2    Murphy, M.F.3
  • 10
    • 0030099573 scopus 로고    scopus 로고
    • A qualitative study to explore the concept of fatigue/tiredness in cancer patients and in healthy individuals
    • Glaus A, Crow R, Hammond S. A qualitative study to explore the concept of fatigue/tiredness in cancer patients and in healthy individuals. Support Care Cancer 1996;4:82-96.
    • (1996) Support Care Cancer , vol.4 , pp. 82-96
    • Glaus, A.1    Crow, R.2    Hammond, S.3
  • 11
    • 4644319149 scopus 로고    scopus 로고
    • The longitudinal relationship of hemoglobin, fatigue and quality of life in anemic cancer patients: Results from five randomized clinical trials
    • Cella D, Kallich J, McDermott A, Xu X. The longitudinal relationship of hemoglobin, fatigue and quality of life in anemic cancer patients: results from five randomized clinical trials. Ann Oncol 2004;15:979-986.
    • (2004) Ann Oncol , vol.15 , pp. 979-986
    • Cella, D.1    Kallich, J.2    McDermott, A.3    Xu, X.4
  • 12
    • 0037080113 scopus 로고    scopus 로고
    • Fatigue in cancer patients compared with fatigue in the general United States population
    • Cella D, Lai JS, Chang CH, et al. Fatigue in cancer patients compared with fatigue in the general United States population. Cancer 2002;94:528-538.
    • (2002) Cancer , vol.94 , pp. 528-538
    • Cella, D.1    Lai, J.S.2    Chang, C.H.3
  • 13
    • 0033530262 scopus 로고    scopus 로고
    • Chemotherapy-induced anemia in adults: Incidence and treatment
    • Groopman JE, Itri LM. Chemotherapy-induced anemia in adults: incidence and treatment. J Natl Cancer Inst 1999;91:1616-1634.
    • (1999) J Natl Cancer Inst , vol.91 , pp. 1616-1634
    • Groopman, J.E.1    Itri, L.M.2
  • 14
    • 0031848408 scopus 로고    scopus 로고
    • Haematological toxicity of cranio-spinal irradiation
    • Jefferies S, Rajan B, Ashley S, et al. Haematological toxicity of cranio-spinal irradiation. Radiother Oncol 1998;48:23-27.
    • (1998) Radiother Oncol , vol.48 , pp. 23-27
    • Jefferies, S.1    Rajan, B.2    Ashley, S.3
  • 15
    • 0033570075 scopus 로고    scopus 로고
    • The importance of hemoglobin levels during radiotherapy for carcinoma of the cervix
    • Grogan M, Thomas GM, Melamed I, et al. The importance of hemoglobin levels during radiotherapy for carcinoma of the cervix. Cancer 1999;86:1528-1536.
    • (1999) Cancer , vol.86 , pp. 1528-1536
    • Grogan, M.1    Thomas, G.M.2    Melamed, I.3
  • 16
    • 34247884344 scopus 로고    scopus 로고
    • Association between anemia arising during therapy and outcomes of chemoradiation for limited small-cell lung cancer
    • Laurie SA, Jeyabalan N, Nicholas G, et al. Association between anemia arising during therapy and outcomes of chemoradiation for limited small-cell lung cancer. J Thorac Oncol 2006;1:146-151.
    • (2006) J Thorac Oncol , vol.1 , pp. 146-151
    • Laurie, S.A.1    Jeyabalan, N.2    Nicholas, G.3
  • 17
    • 0036629604 scopus 로고    scopus 로고
    • Declining hemoglobin during chemoradiotherapy for locally advanced non-small cell lung cancer is significant
    • MacRae R, Shyr Y, Johnson D, Choy H. Declining hemoglobin during chemoradiotherapy for locally advanced non-small cell lung cancer is significant. Radiother Oncol 2002;64:37-40.
    • (2002) Radiother Oncol , vol.64 , pp. 37-40
    • MacRae, R.1    Shyr, Y.2    Johnson, D.3    Choy, H.4
  • 18
    • 1242314294 scopus 로고    scopus 로고
    • Anemia before and during concurrent chemoradiotherapy in patients with cervical carcinoma: Effect on progression-free survival
    • Obermair A, Cheuk R, Horwood K, et al. Anemia before and during concurrent chemoradiotherapy in patients with cervical carcinoma: effect on progression-free survival. Int J Gynecol Cancer 2003;13:633-639.
    • (2003) Int J Gynecol Cancer , vol.13 , pp. 633-639
    • Obermair, A.1    Cheuk, R.2    Horwood, K.3
  • 19
    • 0032735480 scopus 로고    scopus 로고
    • Prognostic impact of total tumor volume and hemoglobin concentration on the outcome of patients with advanced head and neck cancer after concomitant boost radiochemotherapy
    • Rudat V, Dietz A, Schramm O, et al. Prognostic impact of total tumor volume and hemoglobin concentration on the outcome of patients with advanced head and neck cancer after concomitant boost radiochemotherapy. Radiother Oncol 1999;53:119-125.
    • (1999) Radiother Oncol , vol.53 , pp. 119-125
    • Rudat, V.1    Dietz, A.2    Schramm, O.3
  • 21
    • 0028580587 scopus 로고
    • Equilibration of hemoglobin concentration after transfusion in medical inpatients not actively bleeding
    • Wiesen AR, Hospenthal DR, Byrd JC, et al. Equilibration of hemoglobin concentration after transfusion in medical inpatients not actively bleeding. Ann Intern Med 1994;121:278-230.
    • (1994) Ann Intern Med , vol.121 , pp. 278-230
    • Wiesen, A.R.1    Hospenthal, D.R.2    Byrd, J.C.3
  • 22
    • 35148831214 scopus 로고    scopus 로고
    • Prognostic significance of blood transfusions in patients with esophageal cancer treated with combined chemoradiotherapy
    • Kader AS, Lim JT, Berthelet E, et al. Prognostic significance of blood transfusions in patients with esophageal cancer treated with combined chemoradiotherapy. Am J Clin Oncol 2007;30:492-497.
    • (2007) Am J Clin Oncol , vol.30 , pp. 492-497
    • Kader, A.S.1    Lim, J.T.2    Berthelet, E.3
  • 23
    • 0343360868 scopus 로고    scopus 로고
    • A multicenter, randomized, controlled clinical trial of transfusion requirements in critical care. Transfusion Requirements in Critical Care Investigators, Canadian Critical Care Trials Group
    • Hebert PC, Wells G, Blajchman MA, et al. A multicenter, randomized, controlled clinical trial of transfusion requirements in critical care. Transfusion Requirements in Critical Care Investigators, Canadian Critical Care Trials Group. N Engl J Med 1999;340:409-417.
    • (1999) N Engl J Med , vol.340 , pp. 409-417
    • Hebert, P.C.1    Wells, G.2    Blajchman, M.A.3
  • 24
    • 0035118207 scopus 로고    scopus 로고
    • Is a low transfusion threshold safe in critically ill patients with cardiovascular diseases?
    • Hebert PC, Yetisir E, Martin C, et al. Is a low transfusion threshold safe in critically ill patients with cardiovascular diseases? Crit Care Med 2001;29:227-234.
    • (2001) Crit Care Med , vol.29 , pp. 227-234
    • Hebert, P.C.1    Yetisir, E.2    Martin, C.3
  • 25
    • 33749055505 scopus 로고    scopus 로고
    • The continuing risk of transfusion-transmitted infections
    • Blajchman MA, Vamvakas EC. The continuing risk of transfusion-transmitted infections. N Engl J Med 2006;355:1303-1305.
    • (2006) N Engl J Med , vol.355 , pp. 1303-1305
    • Blajchman, M.A.1    Vamvakas, E.C.2
  • 27
    • 0035950684 scopus 로고    scopus 로고
    • Anemia, transfusion, and mortality
    • Goodnough LT, Bach RG. Anemia, transfusion, and mortality. N Engl J Med 2001;345:1272-1274.
    • (2001) N Engl J Med , vol.345 , pp. 1272-1274
    • Goodnough, L.T.1    Bach, R.G.2
  • 28
    • 0037431753 scopus 로고    scopus 로고
    • Transfusion medicine: Looking to the future
    • Goodnough LT, Shander A, Brecher ME. Transfusion medicine: looking to the future. Lancet 2003;361:161-169.
    • (2003) Lancet , vol.361 , pp. 161-169
    • Goodnough, L.T.1    Shander, A.2    Brecher, M.E.3
  • 29
    • 37349104957 scopus 로고    scopus 로고
    • International variation in the use of blood transfusion in patients with non-ST-segment elevation acute coronary syndromes
    • Rao SV, Chiswell K, Sun JL, et al. International variation in the use of blood transfusion in patients with non-ST-segment elevation acute coronary syndromes. Am J Cardiol 2008;101:25-29.
    • (2008) Am J Cardiol , vol.101 , pp. 25-29
    • Rao, S.V.1    Chiswell, K.2    Sun, J.L.3
  • 30
    • 84868956112 scopus 로고    scopus 로고
    • Fatalities reported to the FDA following blood collection and transfusion, and, Last accessed May 19, 2008
    • Fatalities reported to the FDA following blood collection and transfusion. Annual summary for fiscal years 2005 and 2006. www.fda.gov/CBER/ blood/fatal0506.htm. Last accessed May 19, 2008.
    • (2005) Annual summary for fiscal years
  • 31
    • 13144297801 scopus 로고    scopus 로고
    • A new strategy for estimating risks of transfusion-transmitted viral infections based on rates of detection of recently infected donors
    • Busch MP, Glynn SA, Stramer SL, et al. A new strategy for estimating risks of transfusion-transmitted viral infections based on rates of detection of recently infected donors. Transfusion 2005;45:254-264.
    • (2005) Transfusion , vol.45 , pp. 254-264
    • Busch, M.P.1    Glynn, S.A.2    Stramer, S.L.3
  • 32
    • 34848872294 scopus 로고    scopus 로고
    • Current risk for transfusion transmitted infections
    • Dodd RY. Current risk for transfusion transmitted infections. Curr Opin Hematol 2007;14:671-676.
    • (2007) Curr Opin Hematol , vol.14 , pp. 671-676
    • Dodd, R.Y.1
  • 34
    • 0842281750 scopus 로고    scopus 로고
    • Universal leukoreduction decreases the incidence of febrile nonhemolytic transfusion reactions to RBCs
    • King KE, Shirey RS, Thoman SK, et al. Universal leukoreduction decreases the incidence of febrile nonhemolytic transfusion reactions to RBCs. Transfusion 2004;44:25-29.
    • (2004) Transfusion , vol.44 , pp. 25-29
    • King, K.E.1    Shirey, R.S.2    Thoman, S.K.3
  • 35
    • 34547563256 scopus 로고    scopus 로고
    • Human erythrovirus B19 and blood transfusion - an update
    • Parsyan A, Candotti D. Human erythrovirus B19 and blood transfusion - an update. Transfus Med 2007;17:263-278.
    • (2007) Transfus Med , vol.17 , pp. 263-278
    • Parsyan, A.1    Candotti, D.2
  • 36
    • 0242330320 scopus 로고    scopus 로고
    • Risks of transfusion-transmitted infections: 2003
    • Pomper GJ, Wu Y, Snyder EL. Risks of transfusion-transmitted infections: 2003. Curr Opin Hematol 2003;10:412-418.
    • (2003) Curr Opin Hematol , vol.10 , pp. 412-418
    • Pomper, G.J.1    Wu, Y.2    Snyder, E.L.3
  • 38
    • 28044446314 scopus 로고    scopus 로고
    • Understanding the consequences of transfusion-related acute lung injury
    • Shander A, Popovsky MA. Understanding the consequences of transfusion-related acute lung injury. Chest 2005;128:598S-604S.
    • (2005) Chest , vol.128
    • Shander, A.1    Popovsky, M.A.2
  • 39
    • 0842303395 scopus 로고    scopus 로고
    • The effect of prestorage WBC reduction on the rates of febrile nonhemolytic transfusion reactions to platelet concentrates and RBC
    • Yazer MH, Podlosky L, Clarke G, Nahimiak SM. The effect of prestorage WBC reduction on the rates of febrile nonhemolytic transfusion reactions to platelet concentrates and RBC. Transfusion 2004;44:10-15.
    • (2004) Transfusion , vol.44 , pp. 10-15
    • Yazer, M.H.1    Podlosky, L.2    Clarke, G.3    Nahimiak, S.M.4
  • 40
    • 39749189446 scopus 로고    scopus 로고
    • Red blood cell transfusions and iron overload in the treatment of patients with myelodys-plastic syndromes
    • Jabbour E, Kantarjian HM, Koller C, Taher A. Red blood cell transfusions and iron overload in the treatment of patients with myelodys-plastic syndromes. Cancer 2008;112:1089-1095.
    • (2008) Cancer , vol.112 , pp. 1089-1095
    • Jabbour, E.1    Kantarjian, H.M.2    Koller, C.3    Taher, A.4
  • 41
    • 47549103806 scopus 로고    scopus 로고
    • Impact of limiting erythropoiesis-stimulating agent use for chemotherapy-induced anemia on the United States blood supply [abstract]
    • Vekeman F, Bookhart BK, Duh MS, et al. Impact of limiting erythropoiesis-stimulating agent use for chemotherapy-induced anemia on the United States blood supply [abstract]. Community Oncology 2008.
    • (2008) Community Oncology
    • Vekeman, F.1    Bookhart, B.K.2    Duh, M.S.3
  • 42
    • 0035367087 scopus 로고    scopus 로고
    • Effects of epoetin alfa on hematologic parameters and quality of life in cancer patients receiving nonplatinum chemotherapy: Results of a randomized, double-blind, placebo-controlled trial
    • Littlewood TJ, Bajetta E, Nortier JW, et al. Effects of epoetin alfa on hematologic parameters and quality of life in cancer patients receiving nonplatinum chemotherapy: results of a randomized, double-blind, placebo-controlled trial. J Clin Oncol 2001;19:2865-2874.
    • (2001) J Clin Oncol , vol.19 , pp. 2865-2874
    • Littlewood, T.J.1    Bajetta, E.2    Nortier, J.W.3
  • 43
    • 0037151364 scopus 로고    scopus 로고
    • Double-blind, placebo-controlled, randomized phase III trial of darbepoetin alfa in lung cancer patients receiving chemotherapy
    • Vansteenkiste J, Pirker R, Massuti B, et al. Double-blind, placebo-controlled, randomized phase III trial of darbepoetin alfa in lung cancer patients receiving chemotherapy. J Natl Cancer Inst 2002;94:1211-1220.
    • (2002) J Natl Cancer Inst , vol.94 , pp. 1211-1220
    • Vansteenkiste, J.1    Pirker, R.2    Massuti, B.3
  • 44
    • 33646905411 scopus 로고    scopus 로고
    • Recombinant human erythropoietins and cancer patients: Updated meta-analysis of 57 studies including 9353 patients
    • Bohlius J, Wilson J, Seidenfeld J, et al. Recombinant human erythropoietins and cancer patients: updated meta-analysis of 57 studies including 9353 patients. J Natl Cancer Inst 2006;98:708-714.
    • (2006) J Natl Cancer Inst , vol.98 , pp. 708-714
    • Bohlius, J.1    Wilson, J.2    Seidenfeld, J.3
  • 45
    • 37849003198 scopus 로고    scopus 로고
    • Use of epoetin and darbepoetin in patients with cancer: 2007 American Society of Clinical Oncology/American Society of Hematology clinical practice guideline update
    • Rizzo JD, Somerfield MR, Hagerty KL, et al. Use of epoetin and darbepoetin in patients with cancer: 2007 American Society of Clinical Oncology/American Society of Hematology clinical practice guideline update. J Clin Oncol 2008;26:132-149.
    • (2008) J Clin Oncol , vol.26 , pp. 132-149
    • Rizzo, J.D.1    Somerfield, M.R.2    Hagerty, K.L.3
  • 48
    • 47549108351 scopus 로고    scopus 로고
    • FDA advisory committee suggests changes to ESA use. NCI
    • May 15, Available at
    • Phillips C. FDA advisory committee suggests changes to ESA use. NCI Cancer Bulletin, Vol. 4, No. 17. May 15, 2007. Available at: http://www.cancer.gov/ncicancerbulletin/NCl_Cancer_Bulletin_051507/page2.
    • (2007) Cancer Bulletin , vol.4 , Issue.17
    • Phillips, C.1
  • 49
    • 47549107522 scopus 로고    scopus 로고
    • Available at:, Accessed May 19, 2008
    • U.S. Food and Drug Administration. Procrit/Epogen Label. Available at: http://www.fda.gov/cder/foi/label/2008/103234s5164lbl.pdf. Accessed May 19, 2008.
    • Procrit/Epogen Label
  • 50
    • 47549103382 scopus 로고    scopus 로고
    • Available at:, Accessed May 19, 2008
    • U.S. Food and Drug Administration. Mircera Label. Available at: http://www.fda.gov/cder/foi/label/2007/125164lbl.pdf. Accessed May 19, 2008.
    • Mircera Label
  • 51
    • 47549102319 scopus 로고    scopus 로고
    • Available at
    • U.S. Food and Drug Administration. Aranesp Label. Available at: http://www.fda.gov/cder/foi/label/2008/103951s5170lbl.pdf.
    • Aranesp Label
  • 52
    • 24944454286 scopus 로고    scopus 로고
    • Maintaining normal hemoglobin levels with epoetin alfa in mainly nonanemic patients with metastatic breast cancer receiving first-line chemotherapy: A survival study
    • Leyland-Jones B, Semiglazov V, Pawlicki M, et al. Maintaining normal hemoglobin levels with epoetin alfa in mainly nonanemic patients with metastatic breast cancer receiving first-line chemotherapy: a survival study. J Clin Oncol 2005;23:5960-5972.
    • (2005) J Clin Oncol , vol.23 , pp. 5960-5972
    • Leyland-Jones, B.1    Semiglazov, V.2    Pawlicki, M.3
  • 53
    • 0041627742 scopus 로고    scopus 로고
    • Efficacy and safety of darbepoetin alfa in anaemic patients with lymphoproliferative malignancies: A randomized, double-blind, placebo-controlled study
    • Hedenus M, Adriansson M, San Miguel J, et al. Efficacy and safety of darbepoetin alfa in anaemic patients with lymphoproliferative malignancies: a randomized, double-blind, placebo-controlled study. Br] Haematol 2003;122:394-403.
    • (2003) Br] Haematol , vol.122 , pp. 394-403
    • Hedenus, M.1    Adriansson, M.2    San Miguel, J.3
  • 54
    • 0142186283 scopus 로고    scopus 로고
    • Erythropoietin to treat head and neck cancer patients with anaemia undergoing radiotherapy: Randomised, double-blind, placebo-controlled trial
    • Henke M, Laszig R, Rube C, et al. Erythropoietin to treat head and neck cancer patients with anaemia undergoing radiotherapy: randomised, double-blind, placebo-controlled trial. Lancet 2003;362:1255-1260.
    • (2003) Lancet , vol.362 , pp. 1255-1260
    • Henke, M.1    Laszig, R.2    Rube, C.3
  • 55
    • 47549114940 scopus 로고    scopus 로고
    • Overgaard J, HoffC, San Hansen H, et al. Randomized study of the importance of novel erythropoiesis stimulating protein (Aranesp) for the effect of radiotherapy in patients with primary squamous cell carcinoma of the head and neck (HNSCC): the Danish Head and Neck Cancer Group DAHANCA 10 [abstract]. European Journal of Cancer Supplements 2007;5(6):7. Abstract 6LB.
    • Overgaard J, HoffC, San Hansen H, et al. Randomized study of the importance of novel erythropoiesis stimulating protein (Aranesp) for the effect of radiotherapy in patients with primary squamous cell carcinoma of the head and neck (HNSCC): the Danish Head and Neck Cancer Group DAHANCA 10 [abstract]. European Journal of Cancer Supplements 2007;5(6):7. Abstract 6LB.
  • 56
    • 34047221511 scopus 로고    scopus 로고
    • Randomized, double-blind, placebo-controlled trial of erythropoietin in non-small-cell lung cancer with disease-related anemia
    • Wright JR, Ung YC, Julian JA, et al. Randomized, double-blind, placebo-controlled trial of erythropoietin in non-small-cell lung cancer with disease-related anemia. J Clin Oncol 2007;25:1027-1032.
    • (2007) J Clin Oncol , vol.25 , pp. 1027-1032
    • Wright, J.R.1    Ung, Y.C.2    Julian, J.A.3
  • 57
    • 41949140285 scopus 로고    scopus 로고
    • Darbepoetin alfa for the treatment of anemia in patients with active cancer not receiving chemotherapy or radiotherapy: Results of a phase III, multicenter, randomized, double-blind, placebo-controlled study
    • Smith RE Jr, Aapro MS, Ludwig H, et al. Darbepoetin alfa for the treatment of anemia in patients with active cancer not receiving chemotherapy or radiotherapy: results of a phase III, multicenter, randomized, double-blind, placebo-controlled study. J Clin Oncol 2008;26:1040-1050.
    • (2008) J Clin Oncol , vol.26 , pp. 1040-1050
    • Smith Jr, R.E.1    Aapro, M.S.2    Ludwig, H.3
  • 58
    • 46749144280 scopus 로고    scopus 로고
    • FDA receives new data on risks of anemia drugs consistent with previous data on tumor growth and death. January 3, Available at
    • U.S. Food and Drug Administration. Press release: FDA receives new data on risks of anemia drugs consistent with previous data on tumor growth and death. January 3, 2008. Available at: http://www.fda.gov/bbs/topics/NEWS/2008/ NEW01769.html.
    • (2008) Press release
  • 59
    • 38649128164 scopus 로고    scopus 로고
    • Phase III trial to evaluate the efficacy of maintaining hemoglobin levels above 12.0 g/dL with erythropoietin vs above 10.0 g/dL without erythropoietin in anemic patients receiving concurrent radiation and cisplatin for cervical cancer
    • Thomas G, Ali S, Hoebers FJ, et al. Phase III trial to evaluate the efficacy of maintaining hemoglobin levels above 12.0 g/dL with erythropoietin vs above 10.0 g/dL without erythropoietin in anemic patients receiving concurrent radiation and cisplatin for cervical cancer. Gynecol Oncol 2008;108:317-325.
    • (2008) Gynecol Oncol , vol.108 , pp. 317-325
    • Thomas, G.1    Ali, S.2    Hoebers, F.J.3
  • 60
    • 40349103260 scopus 로고    scopus 로고
    • Venous thromboembolism and mortality associated with recombinant erythropoietin and darbepoetin administration for the treatment of cancer-associated anemia
    • Bennett CL, Silver SM, Djulbegovic B, et al. Venous thromboembolism and mortality associated with recombinant erythropoietin and darbepoetin administration for the treatment of cancer-associated anemia. JAMA 2008;299:914-924.
    • (2008) JAMA , vol.299 , pp. 914-924
    • Bennett, C.L.1    Silver, S.M.2    Djulbegovic, B.3
  • 61
    • 33745936043 scopus 로고    scopus 로고
    • Clinical benefits and risks associated with epoetin and darbepoetin in patients with chemotherapy-induced anemia: A systematic review of the literature
    • Ross SD, Allen IE, Henry DH, et al. Clinical benefits and risks associated with epoetin and darbepoetin in patients with chemotherapy-induced anemia: a systematic review of the literature. Clin Ther 2006;28:801-831.
    • (2006) Clin Ther , vol.28 , pp. 801-831
    • Ross, S.D.1    Allen, I.E.2    Henry, D.H.3
  • 62
    • 47549087992 scopus 로고    scopus 로고
    • Erratum in: Clin Ther 2007;29:985-986.
    • Erratum in: Clin Ther 2007;29:985-986.
  • 63
    • 39149121539 scopus 로고    scopus 로고
    • Effect of once-weekly epoetin beta on survival in patients with metastatic breast cancer receiving anthracycline- and/or taxane-based chemotherapy: Results of the Breast Cancer-Anemia and the Value of Erythropoietin (BRAVE) study
    • Aapro M, Leonard RC, Barnadas A, et al. Effect of once-weekly epoetin beta on survival in patients with metastatic breast cancer receiving anthracycline- and/or taxane-based chemotherapy: results of the Breast Cancer-Anemia and the Value of Erythropoietin (BRAVE) study. J Clin Oncol 2008;26:592-598.
    • (2008) J Clin Oncol , vol.26 , pp. 592-598
    • Aapro, M.1    Leonard, R.C.2    Barnadas, A.3
  • 64
    • 34247106263 scopus 로고    scopus 로고
    • A randomized trial comparing immediate versus delayed treatment of anemia with once-weekly epoetin alfa in patients with non-small cell lung cancer scheduled to receive first-line chemotherapy
    • Crawford J, Robert F, Perry MC, et al. A randomized trial comparing immediate versus delayed treatment of anemia with once-weekly epoetin alfa in patients with non-small cell lung cancer scheduled to receive first-line chemotherapy. J Thorac Oncol 2007;2:210-220.
    • (2007) J Thorac Oncol , vol.2 , pp. 210-220
    • Crawford, J.1    Robert, F.2    Perry, M.C.3
  • 65
    • 33644825219 scopus 로고    scopus 로고
    • Efficacy and safety analysis of epoetin alfa in patients with small-cell lung cancer: A randomized, double-blind, placebo-controlled trial
    • Grote T, Yeilding AL, Castillo R, et al. Efficacy and safety analysis of epoetin alfa in patients with small-cell lung cancer: a randomized, double-blind, placebo-controlled trial. J Clin Oncol 2005;23:9377-9386.
    • (2005) J Clin Oncol , vol.23 , pp. 9377-9386
    • Grote, T.1    Yeilding, A.L.2    Castillo, R.3
  • 66
    • 0343238850 scopus 로고    scopus 로고
    • Risk factors for deep vein thrombosis and pulmonary embolism: A population-based case-control study
    • Heit J A, Silverstein MD, Mohr DN, et al. Risk factors for deep vein thrombosis and pulmonary embolism: a population-based case-control study. Arch Intern Med 2000;160:809-815.
    • (2000) Arch Intern Med , vol.160 , pp. 809-815
    • Heit, J.A.1    Silverstein, M.D.2    Mohr, D.N.3
  • 67
    • 34247568441 scopus 로고    scopus 로고
    • Thromboembolism is a leading cause of death in cancer patients receiving outpatient chemotherapy
    • Khorana AA, Francis CW, Culakova E, et al. Thromboembolism is a leading cause of death in cancer patients receiving outpatient chemotherapy. J Thromb Haemost 2007;5:632-634.
    • (2007) J Thromb Haemost , vol.5 , pp. 632-634
    • Khorana, A.A.1    Francis, C.W.2    Culakova, E.3
  • 68
    • 0023818427 scopus 로고
    • The thrombogenic effect of anticancer drug therapy in women with stage II breast cancer
    • Levine MN, Gent M, Hirsh J, et al. The thrombogenic effect of anticancer drug therapy in women with stage II breast cancer. N Engl J Med 1988;318:404-407.
    • (1988) N Engl J Med , vol.318 , pp. 404-407
    • Levine, M.N.1    Gent, M.2    Hirsh, J.3
  • 69
    • 0025981392 scopus 로고
    • Venous and arterial thrombosis in patients who received adjuvant therapy for breast cancer
    • Saphner T, Tormey DC, Gray R. Venous and arterial thrombosis in patients who received adjuvant therapy for breast cancer. J Clin Oncol 1991;9:286-294.
    • (1991) J Clin Oncol , vol.9 , pp. 286-294
    • Saphner, T.1    Tormey, D.C.2    Gray, R.3
  • 70
    • 36849070772 scopus 로고    scopus 로고
    • American Society of Clinical Oncology guideline: Recommendations for venous thromboembolism prophylaxis and treatment in patients with cancer
    • Lyman GH, Khorana AA, Falanga A, et al. American Society of Clinical Oncology guideline: recommendations for venous thromboembolism prophylaxis and treatment in patients with cancer. J Clin Oncol 2007;25:5490-5505.
    • (2007) J Clin Oncol , vol.25 , pp. 5490-5505
    • Lyman, G.H.1    Khorana, A.A.2    Falanga, A.3
  • 71
    • 47549107960 scopus 로고    scopus 로고
    • Evaluation of the association between hemoglobin (Hb) events and safety outcomes in cancer patients (pts) with chemotherapy-induced anemia (CIA): An integrated analysis of patient-level data from 6 randomized, placebo-controlled trials (RCTs) of darbepoetin alfa (DA) [abstract]
    • Abstract 1120
    • Glaspy J, Osterborg A, Ludwig H, et al. Evaluation of the association between hemoglobin (Hb) events and safety outcomes in cancer patients (pts) with chemotherapy-induced anemia (CIA): an integrated analysis of patient-level data from 6 randomized, placebo-controlled trials (RCTs) of darbepoetin alfa (DA) [abstract]. European Journal of Cancer Supplements 2007;5(4):147-147. Abstract 1120.
    • (2007) European Journal of Cancer Supplements , vol.5 , Issue.4 , pp. 147-147
    • Glaspy, J.1    Osterborg, A.2    Ludwig, H.3
  • 72
    • 27744500483 scopus 로고    scopus 로고
    • Long-term outcome of individuals with pure red cell aplasia and antierythropoietin antibodies in patients treated with recombinant epoetin: A follow-up report from the Research on Adverse Drug Events and Reports (RADAR) Project
    • Bennett CL, Cournoyer D, Carson KR, et al. Long-term outcome of individuals with pure red cell aplasia and antierythropoietin antibodies in patients treated with recombinant epoetin: a follow-up report from the Research on Adverse Drug Events and Reports (RADAR) Project. Blood 2005;106:3343-3347.
    • (2005) Blood , vol.106 , pp. 3343-3347
    • Bennett, C.L.1    Cournoyer, D.2    Carson, K.R.3
  • 73
  • 74
    • 47549097069 scopus 로고    scopus 로고
    • Epoetin-associated pure red cell aplasia: Past, present, and future considerations
    • in press. Epub: 14 May
    • McKoy JM, Stonecash RE, Cournoyer D, et al. Epoetin-associated pure red cell aplasia: past, present, and future considerations. Transfusion 2008;in press. Epub: 14 May 2008.
    • (2008) Transfusion 2008
    • McKoy, J.M.1    Stonecash, R.E.2    Cournoyer, D.3
  • 75
    • 47549112002 scopus 로고    scopus 로고
    • 2005 Safety Information Alerts. FDA on ESA-associated PRCA. Posted 1 December 2005. Available at: http://www.fda.gov/medwatch/SAFETY/2005/safety05. htm#epoetin.
    • 2005 Safety Information Alerts. FDA on ESA-associated PRCA. Posted 1 December 2005. Available at: http://www.fda.gov/medwatch/SAFETY/2005/safety05. htm#epoetin.
  • 76
    • 0035366382 scopus 로고    scopus 로고
    • Clinical evaluation of once-weekly dosing of epoetin alfa in chemotherapy patients: Improvements in hemoglobin and quality of life are similar to three-times-weekly dosing
    • Gabrilove JL, Cleeland CS, Livingston RB, et al. Clinical evaluation of once-weekly dosing of epoetin alfa in chemotherapy patients: improvements in hemoglobin and quality of life are similar to three-times-weekly dosing. J Clin Oncol 2001;19:2875-2882.
    • (2001) J Clin Oncol , vol.19 , pp. 2875-2882
    • Gabrilove, J.L.1    Cleeland, C.S.2    Livingston, R.B.3
  • 77
    • 33746105013 scopus 로고    scopus 로고
    • Randomized, open-label comparison of epoetin alfa extended dosing (80 000 U Q2W) vs weekly dosing (40 000 U QW) in patients with chemotherapy-induced anemia
    • Henry DH, Gordan LN, Charu V, et al. Randomized, open-label comparison of epoetin alfa extended dosing (80 000 U Q2W) vs weekly dosing (40 000 U QW) in patients with chemotherapy-induced anemia. Curr Med Res Opin 2006;22:1403-1413.
    • (2006) Curr Med Res Opin , vol.22 , pp. 1403-1413
    • Henry, D.H.1    Gordan, L.N.2    Charu, V.3
  • 78
    • 33644977733 scopus 로고    scopus 로고
    • Phase III study of two different dosing schedules of erythropoietin in anemic patients with cancer
    • Steensma DP, Molina R, Sloan JA, et al. Phase III study of two different dosing schedules of erythropoietin in anemic patients with cancer. J Clin Oncol 2006;24:1079-1089.
    • (2006) J Clin Oncol , vol.24 , pp. 1079-1089
    • Steensma, D.P.1    Molina, R.2    Sloan, J.A.3
  • 79
    • 33144458077 scopus 로고    scopus 로고
    • Randomized, double-blind, active-controlled trial of every-3-week darbepoetin alfa for the treatment of chemotherapy-induced anemia
    • Canon JL, Vansteenkiste J, Bodoky G, et al. Randomized, double-blind, active-controlled trial of every-3-week darbepoetin alfa for the treatment of chemotherapy-induced anemia. J Natl Cancer Inst 2006;98:273-284.
    • (2006) J Natl Cancer Inst , vol.98 , pp. 273-284
    • Canon, J.L.1    Vansteenkiste, J.2    Bodoky, G.3
  • 80
    • 1542346485 scopus 로고    scopus 로고
    • Evaluation of the US Oncology Network's tecommended guidelines for therapeutic substitution with darbepoetin alfa 200 microg every 2 weeks in both naive patients and patients switched from epoetin alfa
    • Thames WA, Smith SL, Scheifele AC, et al. Evaluation of the US Oncology Network's tecommended guidelines for therapeutic substitution with darbepoetin alfa 200 microg every 2 weeks in both naive patients and patients switched from epoetin alfa. Pharmacotherapy 2004;24:313-323.
    • (2004) Pharmacotherapy , vol.24 , pp. 313-323
    • Thames, W.A.1    Smith, S.L.2    Scheifele, A.C.3
  • 81
    • 33645784831 scopus 로고    scopus 로고
    • Darbepoetin alfa administered every three weeks is effective for the treatment of chemotherapy-induced anemia
    • Boccia R, Malik IA, Raja V, et al. Darbepoetin alfa administered every three weeks is effective for the treatment of chemotherapy-induced anemia. Oncologist 2006;11:409-417.
    • (2006) Oncologist , vol.11 , pp. 409-417
    • Boccia, R.1    Malik, I.A.2    Raja, V.3
  • 82
    • 0031713670 scopus 로고    scopus 로고
    • Supplemental iron: A key to optimizing the response of cancer-related anemia to rHuEPO?
    • Henry DH. Supplemental iron: a key to optimizing the response of cancer-related anemia to rHuEPO? Oncologist 1998;3:275-278.
    • (1998) Oncologist , vol.3 , pp. 275-278
    • Henry, D.H.1
  • 83
    • 14744278436 scopus 로고    scopus 로고
    • Anemia of chronic disease
    • Weiss G, Goodnough LT. Anemia of chronic disease. N Engl J Med 2005;352:1011-1023.
    • (2005) N Engl J Med , vol.352 , pp. 1011-1023
    • Weiss, G.1    Goodnough, L.T.2
  • 84
    • 2142825053 scopus 로고    scopus 로고
    • Intravenous iron optimizes the response to recombinant human erythropoietin in cancer patients with chemotherapy-related anemia: A multicenter, open-label, randomized trial
    • Auerbach M, Ballard H, Trout JR, et al. Intravenous iron optimizes the response to recombinant human erythropoietin in cancer patients with chemotherapy-related anemia: a multicenter, open-label, randomized trial. J Clin Oncol 2004;22:1301-1307.
    • (2004) J Clin Oncol , vol.22 , pp. 1301-1307
    • Auerbach, M.1    Ballard, H.2    Trout, J.R.3
  • 85
    • 33847046008 scopus 로고    scopus 로고
    • Intravenous ferric gluconate significantly improves response to epoetin alfa versus oral iron or no iron in anemic patients with cancer receiving chemotherapy
    • Henry DH, Dahl NV, Auerbach M, et al. Intravenous ferric gluconate significantly improves response to epoetin alfa versus oral iron or no iron in anemic patients with cancer receiving chemotherapy. Oncologist 2007;12:231-242.
    • (2007) Oncologist , vol.12 , pp. 231-242
    • Henry, D.H.1    Dahl, N.V.2    Auerbach, M.3
  • 86
    • 33947405774 scopus 로고    scopus 로고
    • Addition of intravenous iron to epoetin beta increases hemoglobin response and decreases epoetin dose requirement in anemic patients with lymphoproliferative malignancies: A randomized multicenter study
    • Hedenus M, Birgegard G, Nasman P, et al. Addition of intravenous iron to epoetin beta increases hemoglobin response and decreases epoetin dose requirement in anemic patients with lymphoproliferative malignancies: a randomized multicenter study. Leukemia 2007;21:627-632.
    • (2007) Leukemia , vol.21 , pp. 627-632
    • Hedenus, M.1    Birgegard, G.2    Nasman, P.3
  • 87
    • 43249129663 scopus 로고    scopus 로고
    • Randomized, multicenter, controlled trial comparing the efficacy and safety of darbepoetin alpha administered every 3 weeks with or without intravenous iron in patients with chemotherapy-induced anemia
    • Bastit L, Vandebroek A, Altintas S, et al. Randomized, multicenter, controlled trial comparing the efficacy and safety of darbepoetin alpha administered every 3 weeks with or without intravenous iron in patients with chemotherapy-induced anemia. J Clin Oncol 2008;26:1611-1618.
    • (2008) J Clin Oncol , vol.26 , pp. 1611-1618
    • Bastit, L.1    Vandebroek, A.2    Altintas, S.3
  • 88
    • 43249121140 scopus 로고    scopus 로고
    • Randomized trial of intravenous iron supplementation in patients with chemotherapy-related anemia without iron deficiency treated with darbepoetin alpha
    • Pedrazzoli P, Farris A, Del Prete S, et al. Randomized trial of intravenous iron supplementation in patients with chemotherapy-related anemia without iron deficiency treated with darbepoetin alpha. J Clin Oncol 2008;26:1619-1625.
    • (2008) J Clin Oncol , vol.26 , pp. 1619-1625
    • Pedrazzoli, P.1    Farris, A.2    Del Prete, S.3
  • 91
    • 34247615981 scopus 로고    scopus 로고
    • Clinical update: Intravenous iron for anaemia
    • Auerbach M, Ballard H, Glaspy J. Clinical update: intravenous iron for anaemia. Lancet 2007;369:1502-1504.
    • (2007) Lancet , vol.369 , pp. 1502-1504
    • Auerbach, M.1    Ballard, H.2    Glaspy, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.