On-chip, time-correlated, fluorescence lifetime extraction algorithms and error analysis

Journal of the Optical Society of America A: Optics and Image Science, and Vision

Volumn 25, Issue 5, 2008, Pages 1190-1198

  Li, Day Uei ^a   Bonnist, Eleanor ^a   Renshaw, David ^a   Henderson, Robert ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALGORITHMS; DIAGNOSIS; ERROR ANALYSIS; ERROR STATISTICS; FLUORESCENCE; MONTE CARLO METHODS; MOSFET DEVICES; TIMING JITTER;

BIT RESOLUTIONS; CHANNEL WIDTHS; CLINICAL DIAGNOSIS; DIRECT CALCULATIONS; EXPERIMENTAL DATUM; EXPONENTIAL DECAYS; EXTRACTION ALGORITHMS; FLUORESCENCE LIFE-TIME; GENERAL PURPOSE; IMAGING MICROSCOPIES; LEAST-SQUARES METHODS; MAXIMUM-LIKELIHOOD; MONTE CARLO SIMULATIONS; ON CHIPS; PHOTON COUNTS; REAL-TIME APPLICATIONS; SIGNAL TO NOISE; STATISTICS THEORIES; TIME-TO-DIGITAL CONVERTERS;

MAXIMUM LIKELIHOOD ESTIMATION;

ALGORITHM; ARTICLE; COMPUTER ASSISTED DIAGNOSIS; FLUORESCENCE MICROSCOPY; IMAGE ENHANCEMENT; INFORMATION RETRIEVAL; METHODOLOGY; MICROCHIP ANALYSIS; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY;

ALGORITHMS; IMAGE ENHANCEMENT; IMAGE INTERPRETATION, COMPUTER-ASSISTED; INFORMATION STORAGE AND RETRIEVAL; MICROCHIP ANALYTICAL PROCEDURES; MICROSCOPY, FLUORESCENCE; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY;

EID: 47549114871     PISSN: 10847529     EISSN: 15208532     Source Type: Journal    
DOI: 10.1364/JOSAA.25.001190     Document Type: Article

References (17)

1. W. Becker, Advanced Time-Correlated Single Photon Counting Techniques (Wolfgang, Springer, 2005).
2. R. Cubeddu, D. Comelli, C. D'Andrea, P. Taroni, and G. Valentini, "Time-resolved fluorescence imaging in biology and medicine," J. Phys. D 35, R61-R76 (2002).
3. R. K. Neely, D. Daujotyte, S. Grazulis, S. W. Magennis, D. T. F. Dryden, S. Klimasauskas, and A. C. Jones, "Time resolved fluorescence of 2-aminopurine as a probe of base flipping in M. Hhal-DNA complexes," Nucleic Acids Res. 33, 6953-6960 (2005).
4. V. V. Apanasovich and E. G. Novikov, "Methods of analysis of fluorescence decay curves in pulsed fluorometry (Review)," J. Appl. Spectrosc. 56, 317-327 (1992).
5. J. Philips and K. Carlsson, "Theoretical investigation of the signal-to-noise ratio in fluorescence lifetime imaging," J. Opt. Soc. Am. A 20, 368-379 (2003).
6. Z. Bajzer, A. C. Myers, S. S. Sedarous, and F. G. Prendergast, "Padé-Laplace method for analysis of fluorescence intensity decay," Biophys. J. 56, 79-93 (1989).
7. P. Hall and B. Sellnger, "Better estimates of exponential decay parameters," J. Phys. Chem. 85, 2941-2946 (1981).
8. M. Maus, M. Cotlet, J. Hofkens, T. Gensch, F. C. De Schryver, J. Schaffer, and C. A. M. Seidel, "An experimental comparison of the maximum likelihood estimation and nonlinear least-squares fluorescence lifetime analysis of single molecules," Anal. Chem. 73, 2078-2086 (2001).
9. S. D. Foss, "A method of exponential curve fitting by numerical integration," Biometrics 26, 815-821 (1970).
10. J. A. Jo, Q. Fang, T. Papaioannou, and L. Marcu, "Novel ultra-fast deconvolution method for fluorescence lifetime imaging microscopy based on the Laguerre expansion technique," in Proceedings of 26th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (IEEE, 2004), pp. 1271-1274.
11. W. Becker, A. Bergmann, C. Biskup, L. Kelbauskas, T. Zimmer, N. Klöcker, and K. Bennodorf, "High resolution TCSPC lifetime imaging," Proc. SPIE 4963, 175-184 (2003).
12. A. Rochas, "Single photon avalanche diodes in CMOS technology," Ph.D. thesis, (Lausanne, 2003).
13. C. Niclass, A. Rochas, P. A. Besse, and E. Charbon, "Toward a 3-D camera based on single photon avalanche diodes," IEEE J. Sel. Top. Quantum Electron. 10, 769-802 (2004).
14. R. M. Ballew and J. N. Demas, "An error analysis of the rapid lifetime determination method for the evaluation of single exponential decays," Anal. Chem. 61, 30-33 (1989).
15. A. Draaijer, R. Sanders, and H. C. Gerritsen, "Fluorescence lifetime imaging, a new tool in confocal microscopy," in Handbook of Biological Confocal Microscopy, J. Pawley, ed. (Plenum, 1995), pp. 491-505.
16. M. Köllner and J. Wolfrum, "How many photons are necessary for fluorescence lifetime measurements?" Chem. Phys. Lett. 200, 199-204 (1992).
17. J. R. Lakowicz and H. Szmacinski, "Fluorescence lifetimebased sensing of pH, Ca+2, K+ and glucose," Sens. Actuators B 11, 133-143 (1993).