Protective effects of edaravone against ischemia-induced facial palsy

Auris Nasus Larynx

Volumn 35, Issue 3, 2008, Pages 321-327

  Takeda, Taizo ^a   Takeda, Setsuko ^a   Takumida, Masaya ^b   Okada, Teruhiko ^a   Kakigi, Akinobu ^a   Nakatani, Hiroaki ^a   Hamada, Masashi ^a   Yamakawa, Kazuhiro ^a  

^a KOCHI MEDICAL SCHOOL   (Japan)

^b HIROSHIMA UNIVERSITY   (Japan)

Author keywords

Acute facial palsy; Edaravone; Free radical scavenger; Ischemia; Reactive oxygen species (ROS)

Indexed keywords

AMINE; DIHYDROTETRAMETHYLROSAMINE; NORPHENAZONE; REACTIVE OXYGEN METABOLITE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY; ARTICLE; ATTENUATION; CONTROLLED STUDY; DISEASE COURSE; DRUG EFFECT; EAR; ELECTRON MICROSCOPY; FACE; FACIAL NERVE; FACIAL NERVE PARALYSIS; FLUORESCENCE; GUINEA PIG; INCIDENCE; INJECTION; ISCHEMIA; MORPHOLOGY; MOTION; NERVE INJURY; NONHUMAN; PETROSAL ARTERY; PROTECTION;

ANIMALS; ANTIPYRINE; AXONS; BLINKING; FACIAL NERVE; FACIAL PARALYSIS; FREE RADICAL SCAVENGERS; GENICULATE GANGLION; GUINEA PIGS; INJECTIONS, INTRAPERITONEAL; ISCHEMIA; MICROSCOPY, ELECTRON; MICROSCOPY, FLUORESCENCE; MYELIN SHEATH; REACTIVE OXYGEN SPECIES;

EID: 47549108482     PISSN: 03858146     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.anl.2007.08.009     Document Type: Article

References (15)

1. Takeda T., Takeda S., Kozakura K., and Saito H. An animal model of ischemic facial palsy. Eur Arch Otorhinolaryngol (1994) S418-S419
2. Takeda T., Takeda S., Kozakura K., and Saito H. Intratemporal facial nerve blood flow in guinea pigs. Am J Otol 18 (1997) 252-256
3. Droge W. Free radicals in the physiological control of cell function. Physiol Rev 82 (2002) 47-95
4. Sum A.Y., and Chen Y.M. Oxidative stress and neurodegenerative disorders. J Biomed Sci 5 (1998) 401-414
5. Watanabe T., Morita I., Nishi H., and Murota S. Preventive effect of MCI-186 on 15-HPETE induced vascular endothelial cell injury in vitro. Prostaglandins Leukot Essent Fatty Acids 33 (1988) 81-87
6. Murata S., Morita I., and Suda N. The control of vascular endothelial cell injury. Ann N Y Acad Sci 598 (1990) 182-187
7. Yagi H., Horinaka S., and Matsuoka H. Edaravone prevented deteriorated cardiac function after myocardial ischemia-reperfusion via inhibiting lipid peroxidation in rat. J Cardiovasc Pharmacol 46 (2005) 46-51
8. Shgichinohe H., Kuroda S., Ysuda H., Ishikawa T., Iwai M., Horiuchi, et al. Neuroprotective effects of the free radical scavenger edaravone (MCI-186) in mice permanent focal brain ischemia. Brain Res 1029 (2004) 200-206
9. Voeikov V.L. Reactive oxygen species (ROS) pathogens or source of vital energy? ROS in normal and pathologic physiology of living systems. J Altern Complement Med 12 (2006) 111-118
10. Li C., and Jackson R.M. Reactive species mechanism of cellular hypoxia-reoxygenation injury. Am J Physiol Cell Physiol 282 (2002) C227-C241
11. Takeda S, Takeda T, Okada T, Nakatani H, Hamada M, Kakigi A. An animal model of ischemic facial palsy. Its behavioral facial nerve function and ultrastructural changes of the facial nerve. ORL J Otorhinolaryngol Relat Spec, in press.
12. Murakami S., Mizobuchi M., Nakashiro Y., Doi T., Hato N., and Yanagihara N. Bell palsy and herpes simplex virus: identification of viral DNA in endoneurial fluid and muscle. Ann Intern Med 124 (1996) 27-30
13. Furuta Y., Fukuda S., Chida E., Takasu T., Ohtani F., Inuyama Y., et al. Reactivation of herpes simplex virus type 1 in patients with Bell's palsy. J Med Virol 54 (1998) 162-166
14. Furuta Y., Ohtani F., Kawabata H., Fukda S., and Bergstrom. High prevalence of Varicella-zoster virus reactivation in Herpes Simplex virus-seronegative patients with acute peripheral facial palsy. CID 30 (2000) 529-533
15. Devriese P.P. Bell palsy and herpes simple virus. Ann Intern Med 125 (1996) 698