Cervical lymph node metastases of squamous cell carcinoma from an unknown primary: Outcomes and patterns of failure

Indian Journal of Cancer

Volumn 45, Issue 2, 2008, Pages 54-58

  Mistry, R ^a   Qureshi, S ^a   Talole, S ^a   Deshmukh, S ^a  

^a TATA MEMORIAL HOSPITAL   (India)

Author keywords

Cervical metastases; Head and neck; Squamous cell carcinoma; Unknown primary

Indexed keywords

ADULT; AGED; ARTICLE; CANCER OF UNKNOWN PRIMARY SITE; FEMALE; HUMAN; LYMPH NODE METASTASIS; MALE; METASTASIS; MIDDLE AGED; MORTALITY; NECK; PATHOLOGY; SQUAMOUS CELL CARCINOMA;

ADULT; AGED; AGED, 80 AND OVER; CARCINOMA, SQUAMOUS CELL; FEMALE; HUMANS; LYMPHATIC METASTASIS; MALE; MIDDLE AGED; NECK; NEOPLASMS, UNKNOWN PRIMARY;

EID: 47549107426     PISSN: 0019509X     EISSN: 19984774     Source Type: Journal    
DOI: 10.4103/0019-509X.41771     Document Type: Article

References (26)

1. Nieder C, Gregoire V, Ang KK. Cervical lymph node metastases from occult squamous cell carcinoma: Cut down a tree to get an apple? Int J Radiat Oncol Biol Phys 2001;50:727-33.
2. Sinnathamby K, Peters LJ, Laidlaw C, Hughes PG. The occult head and neck primary: To treat or not to treat? Clin Oncol (R Coll Radiol) 1997;9:322-9.
3. Grau C, Johansen LV, Jakobsen J, Geertsen P, Andersen E, Jensen BB. Cervical lymph node metastases from unknown primary tumours. Results from a national survey by the Danish Society for Head and Neck Oncology. Radiother Oncol 2000;55:121-9.
4. Colletier PJ, Garden AS, Morrison WH, Goepfert H, Geara F, Ang KK. Postoperative radiation for squamous cell carcinoma metastatic to cervical lymph nodes from an unknown primary site: Outcomes and patterns of failure. Head Neck 1998;20:674-81.
5. Reddy SP, Marks JE. Metastatic carcinoma in the cervical lymph nodes from an unknown primary site: Results of bilateral neck plus mucosal irradiation vs. ipsilateral neck irradiation. Int J Radiat Oncol Biol Phys 1997;37:797-802.
6. Erkal HS, Mendenhall WM, Amdur RJ, Villaret DB, Stringer SP. Squamous cell carcinomas metastatic to cervical lymph nodes from an unknown head-and-neck mucosal site treated with radiation therapy alone or in combination with neck dissection. Int J Radiat Oncol Biol Phys 2001;50:55-63.
7. Iganej S, Kagan R, Anderson P, Rao A, Tome M, Wang R, et al. Metastatic squamous cell carcinoma of the neck from an unknown primary: Management options and patterns of relapse. Head Neck 2002;24:236-46.
8. Tong CC, Luk MY, Chow SM, Ngan KC, Lau WH. Cervical nodal metastases from occult primary: Undifferentiated carcinoma versus squamous cell carcinoma. Head Neck 2002;24:361-9.
9. McMahon J, Hruby G, O'Brien CJ, McNeil EB, Bagia JS, Clifford AR, et al. Neck dissection and ipsilateral radiotherapy in the management of cervical metastatic carcinoma from an unknown primary. Aust N Z J Surg 2000;70:263-8.
10. Shenoy AM, Hasan S, Nayak U, Anantha N, Reddy BK, Kannan V, et al. Neck metastasis from an occult primary - the Kidwai experience. Indian J Cancer 1992;29:203-9.
11. th ed. New York: Springer-Verlag; 2002. p. 17-22.
12. Dinshaw KA, Rao DN, Shroff PD. Annual Report 1987, Hospital Cancer Registry. Mumbai: Tata Memorial Hospital; 1989.
13. Lapeyre M, Malissard L, Peiffert D, Hoffstetter S, Toussaint B, Renier S, et al. Cervical lymph node metastasis from an unknown primary: Is a tonsillectomy necessary? Int J Radiat Oncol Biol Phys 1997;39:291-6.
14. Jereczek-Fossa BA, Jassem J, Orecchia R. Cervical lymph node metastases of squamous cell carcinoma from an unknown primary. Cancer Treat Rev 2004;30:153-64.
15. Mendenhall WM, Mancuso AA, Amdur RJ, Stringer SP, Villaret DB, Cassisi NJ. Squamous cell carcinoma metastatic to the neck from an unknown head and neck primary site. Am J Otolaryngol 2001;22:261-7.
16. Weickert U, Jakobs R, Riemann JF. Diagnostic laparoscopy. Endoscopy 2005;37:33-7.
17. rd. Occult primary tumors of the head and neck: Lack of benefit from positron emission tomography imaging with 2-[F-18]fluoro-2-deoxy-D-glucose. Cancer 1999;86:114-8.
18. Kulapaditharom B, Boonkitticharoen V, Kunachak S. Flourescence-guided biopsy in the diagnosis of an unknown primary in patients with metastatic cervical lymph nodes. Ann Otol Rhinol Laryngol 1999;108:700-4.
19. Lee WY, Hsiao JR, Jin YT, Tsai ST. Epstein-Barr virus detection in neck metastases by in-situ hybridization in fine needle aspiration cytologic studies: An aid differentiating the primary site. Head Neck 2000;22:336-40.
20. Gillison ML, Koch WM, Capone RB, Spafford M, Westra WH, Wu L, et al. Evidence for a causal association between human papillomavirus and a subset of head and neck cancers. J Natl Cancer Inst 2000;92:709-20.
21. Califano J, Westra WH, Koch W, Meininger G, Reed A, Yip L, et al. Unknown primary head and neck squamous cell carcinoma: molecular identification of the site of origin. J Natl Cancer Inst 1999;91:599-604.
22. Strojan P, Anicin A. Combined surgery and postoperative radiotherapy for cervical lymph node metastases from an unknown primary tumour. Radiother Oncol 1998;49:33-40.
23. Davidson BJ, Spiro RH, Patel S, Patel K, Shah JP. Cervical metastases of occult origin: The impact of combined modality therapy. Am J Surg 1994;168:395-9.
24. Fernandez JA, Suarez C, Martinez JA, Llorente JL, Rodrigo JP, Alvarez JC. Metastatic squamous cell carcinoma in cervical lymph nodes from an unknown primary tumour: prognostic factors. Clin Otolaryngol Allied Sci 1998;23:158-63.
25. Weir L, Keane T, Cummings B, Goodman P, O'Sullivan B, Payne D, et al. Radiation treatment of cervical lymph node metastases from an unknown primary: An analysis of outcome by treatment volume and other prognostic factors. Radiother Oncol 1995;35:206-11.
26. Jones AS, Cook JA, Phillips DE, Roland NR. Squamous carcinoma presenting as an enlarged cervical lymph node. Cancer 1993;27:1756-61.