Platelet-activating factor (PAF) induced cytokine production and otitis media with effusion (OME) in the rat middle ear

Auris Nasus Larynx

Volumn 35, Issue 3, 2008, Pages 338-343

  Ogura, Manabu ^a   Furukawa, Masayuki ^a   Tada, Naoki ^a   Ikeda, Hiroki ^a   Yamashita, Toshio ^a  

^a KANSAI MEDICAL UNIVERSITY   (Japan)

Author keywords

Cytokine; Otitis media with effusion; PAF acetylhydrolase; Platelet activating factor

Indexed keywords

1 ALKYL 2 ACETYLGLYCEROPHOSPHOCHOLINE ESTERASE; BEPAFANT; INTERLEUKIN 8; THROMBOCYTE ACTIVATING FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL CULTURE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOSE RESPONSE; ENZYME LINKED IMMUNOSORBENT ASSAY; MALE; NONHUMAN; OTITIS MEDIA; RADIOIMMUNOASSAY; RAT; THROMBOCYTE AGGREGATION;

1-ALKYL-2-ACETYLGLYCEROPHOSPHOCHOLINE ESTERASE; ANIMALS; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; EPITHELIAL CELLS; INTERLEUKIN-8; MALE; OTITIS MEDIA WITH EFFUSION; PLATELET ACTIVATING FACTOR; RATS; RATS, WISTAR;

EID: 47549105344     PISSN: 03858146     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.anl.2007.09.009     Document Type: Article

References (19)

1. Jung T.T.K. Prostaglandins, leukotrienes, and other arachidonic acid metabolites in the pathogenesis of otitis media. Laryngoscope 98 (1988) 980-993
2. Van Cauwenberge P.B., and Bernstein J.M. Inflammatory mediators in middle ear disease. In: Bernstein J.M., and Ogura P.L. (Eds). Immunology of the ear (1987), Raven Press, New York 331-343
3. Furukawa M., Kubo N., and Yamashita T. Biochemical evidence of platelet-activating factor (PAF) in human middle ear effusions. Laryngoscope 105 (1995) 188-191
4. Jung T.T.K., Park Y.M., Schlnnd D., Weeks D., Miller S., Wong O., et al. Effect of prostaglandin, Leukotriene, and arachidonic acid on experimental otitis media with effusion in chinchillas. Ann Otol Laryngol 99 (1990) 28-32
5. Rhee C.-K., Jung T.T.K., Miller S., and Weeks D. Experiment otitis media with effusion induced by platelet activating factor. Ann Otol Laryngol 102 (1993) 660-665
6. Snyder F. Platelet-activating factor and related acetylated lipids as potent biologically active cellular mediators. Am J Physiol 259 (1990) 697-708
7. Pei Y., Barber L.A., Murphy R.C., Johnson C.A., Kelley S.W., Dy L.C., et al. Activation of epidermal platelet-activating factor receptor results in cytokine and cyclooxygenase-2 biosynthesis. J Immunol 161 (1998) 1954-1961
8. Sugano T., Narahara H., Nasu K., Arima K., Fujisawa K., and Isao M. Effect of platelet-activating factor on cytokine production by human uterine cervical fibroblasts. Mol Hum Reprod 7 (2001) 475-481
9. Smirnova M.G., Kiselev S.L., Gnuchev N.V., Birchall J.P., and Pearson J.P. Role of the pro-inflammatory cytokines tumor necrosis factor-α, interleukin-1β, interleukin-6 and interleukin-8 in the pathogenesis of the otitis media with effusion. Eur Cytokine Netw 13 (2002) 162-172
10. Yellon R.F., Leonard G., Marucha P.T., Craven R., Carpenter R.J., Lehmann W.B., et al. Characterization of cytokines present in middle ear effusions. Laryngoscope 101 (1991) 165-169
11. Sato K., Liebeler C.L., Quarty M.K., Le C.T., and Giebink G.S. Middle ear fluid cytokine and inflammatory cell kinetics in the chinchilla otitis media model. Infect Immunol 67 (1999) 1943-1946
12. Tjoelker L.W., and Stafforini D.M. Platelet-activating factor acetylhydrolases in health and disease. Biochem Biophys Acta 1488 (2000) 102-123
13. Tsuji H., Furukawa M., Ikeda H., Asako M., and Yamashita T. The presence of platelet-activating factor acetylhydrolase on human middle ear effusions. ORL J Otorhinolaryngol Relat Spec 60 (1998) 25-29
14. Bazan H.E.P., Tao Y., and Bazan N.G. Platelet-activating factor induces collagenase expression in corneal epithelial cells. Proc Natl Acad Sci USA 90 (1993) 8678-8682
15. Karasen R.M., Sutbeyaz Y., Aktan B., Ozdemir H., and Gundogdu C. Effect of WEB 2170 BS, platelet activating factor receptor inhibitor, in the guinea pig model of middle ear inflammation. Ann Otol Rhinol Laryngol 109 (2000) 549-553
16. van Blitterswijk C.A., Ponec M., van Muijen G.N., Wijsman M.C., Koerten H.K., and Grote J.J. Culture and characterization of rat middle-ear epithelium. Acta Otolaryngol 101 (1986) 453-466
17. 4. Auris Nasus Larynx 29 (2002) 127-132
18. Miwa M., Miyake T., Yamanaka T., Sugatani J., Suzuki Y., Sakata S., et al. Characterization of serum platelet-activating factor (PAF) acetylhydrolase: correlation between deficiency of serum PAF acetylhydrolase and respiratory symptoms in asthmatic children. J Clin Invest 82 (1988) 1983-1991
19. Tjoelker L.W., Wilder C., Eberhardt C., Stafforini D.M., Pietsch G., Schimpf B., et al. Anti-inflammatory properties of a platelet-activating factor acetylhydrolase. Nature 374 (1995) 549-553