Dehydrogenase interference with enzymatic ethanol assays: Forgotten but not gone

Clinical Chemistry

Volumn 54, Issue 7, 2008, Pages 1251-1252

  Gharapetian, Angineh ^a   Holmes, Daniel T ^a,b   Urquhart, Nadine ^a   Rosenberg, Frances ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b ST PAUL S HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCYSTEINE; ALANINE AMINOTRANSFERASE; ALCOHOL DEHYDROGENASE; LACTATE DEHYDROGENASE; PARACETAMOL; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE;

ABDOMINAL PAIN; ALANINE AMINOTRANSFERASE BLOOD LEVEL; EMERGENCY WARD; ENZYMATIC ASSAY; GAS CHROMATOGRAPHY; GASTRITIS; LACTATE DEHYDROGENASE BLOOD LEVEL; LETTER; LIVER NECROSIS; OSMOLALITY; PATIENT SAFETY; SPECTROPHOTOMETRY;

ACETAMINOPHEN; ETHANOL; FALSE POSITIVE REACTIONS; HUMANS; L-LACTATE DEHYDROGENASE; LACTIC ACID; LIVER; NECROSIS;

EID: 47549101621     PISSN: 00099147     EISSN: None     Source Type: Journal    
DOI: 10.1373/clinchem.2008.103853     Document Type: Letter

References (4)

1. Purssell RA, Pudek M, Brubacher J, Abu-Laban RB. Derivation and validation of a formula to calculate the contribution of ethanol to the osmolal gap. Ann Emerg Med 2001;38:653-9.
2. Badcock NR, O'Reilly DA. False-positive EMIT-st ethanol screen with post-mortem infant plasma. Clin Chem 1992;38:434.
3. Nine JS, Moraca M, Virji MA, Rao KN. Serum-ethanol determination: comparison of lactate dehydrogenase interference in three enzymatic assays. J Anal Toxicol 1995;19:192-6.
4. Thompson WC, Malhotra D, Schammel DP, Blackwell W, Ward ME, Dasgupta A. False-positive ethanol in clinical and postmortem sera by enzymatic assay: elimination of interference by measuring alcohol in protein-free ultrafiltrate. Clin Chem 1994;40:1594-5.