Ectopic testicular xenografts from newborn hamsters (Phodopus sungorus) show better spermatogenic activity in aged compared with young recipients

Journal of Experimental Zoology Part A: Ecological Genetics and Physiology

Volumn 309, Issue 5, 2008, Pages 278-287

  Ehmcke, Jens ^a   Gassei, Kathrin ^a   Schlatt, Stefan ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CRICETINAE; MUS; MUS MUSCULUS; PHODOPUS; PHODOPUS SUNGORUS;

AGING; ANIMAL; ARTICLE; COMPARATIVE STUDY; HAMSTER; MALE; NEWBORN; ORCHIECTOMY; PHODOPUS; PHYSIOLOGY; SPERMATOGENESIS; TESTIS; TRANSPLANTATION; XENOGRAFT;

AGING; ANIMALS; ANIMALS, NEWBORN; CRICETINAE; MALE; ORCHIECTOMY; PHODOPUS; SPERMATOGENESIS; TESTIS; TRANSPLANTATION, HETEROLOGOUS;

EID: 47549096241     PISSN: 19325223     EISSN: None     Source Type: Journal    
DOI: 10.1002/jez.459     Document Type: Article

References (39)

1. Bosch M, Rajmil O, Martinez-Pasarell O, Egozcue J, Templado C. 2001. Linear increase of diploidy in human sperm with age: a four-colour FISH study. Eur J Hum Genet 9:533-538.
2. Bradley BA. 2002. Rejection and recipient age. Transpl Immunol 10:125-132.
3. Brinkworth MH, Weinbauer GF, Bergmann M, Nieschlag E. 1997. Apoptosis as a mechanism of germ cell loss in elderly men. Int J Androl 20:222-228.
4. Cargill SL, Carey JR, Muller HG, Anderson G. 2003. Age of ovary determines remaining life expectancy in old ovariectomized mice. Aging Cell 2:185-190.
5. Chaffee RRJ, Hensley JC, Spalding JF. 1965. Heritable radiation effects on mouse body and organ weights, fat deposition, cellular enzymes, and blood. Genetics 53:875-882.
6. Chen H, Huhtaniemi I, Zirkin BR. 1996. Depletion and repopulation of Leydig cells in the testes of aging brown Norway rats. Endocrinology 137:3447-3452.
7. Danovitch GM, Gill J, Bunnapradist S. 2007. Immunosuppression of the elderly kidney transplant recipient. Transplantation 84:285-291.
8. de Miguel MP, Bethencourt FR, Arenas MI, Fraile B, Paniagua R. 1997. Intermediate filaments in the Sertoli cells of the ageing human testis. Virchows Arch 431:131-138.
9. Dobrinski I, Ogawa T, Avarbock MR, Brinster RL. 2001. Effect of the GnRH-agonist leuprolide on colonization of recipient testes by donor spermatogonial stem cells after transplantation in mice. Tissue Cell 33:200-207.
10. Ehmcke J, Joshi B, Hergenrother SD, Schlatt S. 2007. Aging does not affect spermatogenic recovery after experimentally induced injury in mice. Reproduction 133:75-83.
11. Eskenazi B, Wyrobek AJ, Sloter E, Kidd SA, Moore L, Young S, Moore D. 2003. The association of age and semen quality in healthy men. Hum Reprod 18:447-454.
12. Haidl G, Jung A, Schill WB. 1996. Ageing and sperm function. Hum Reprod 11:558-560.
13. Honore LH. 1978. Ageing changes in the human testis: a light-microscopic study. Gerontology 24:58-65.
14. Johnson L. 1986. Spermatogenesis and aging in the human. J Androl 7:331-354.
15. Johnson L. 1989. Evaluation of the human testis and its age-related dysfunction. Prog Clin Biol Res 302:35-67.
16. Kimura M, Itoh N, Takagi S, Sasao T, Takahashi A, Masumori N, Tsukamoto T. 2003. Balance of apoptosis and proliferation of germ cells related to spermatogenesis in aged men. J Androl 24:185-191.
17. Levy S, Serre V, Hermo L, Robaire B. 1999. The effects of aging on the seminiferous epithelium and the blood-testis barrier of the brown Norway rat. J Androl 20:356-365.
18. Li W, Ayata M, Terada N, Taniguchi H, Matsumoto K. 1989. Effect of androgen pretreatments at adulthood on androgen-induced proliferative response of seminal vesicles in neonatally castrated mice. J Steroid Biochem 33:59-63.
19. Lowe X, Eskenazi B, Nelson DO, Kidd S, Alme A, Wyrobek AJ. 2001. Frequency of XY sperm increases with age in fathers of boys with Klinefelter syndrome. Am J Hum Genet 69:1046-1054.
20. Luetjens CM, Rolf C, Gassner P, Werny JE, Nieschlag E. 2002. Sperm aneuploidy rates in younger and older men. Hum Reprod 17:1826-1832.
21. Matsumiya K, Meistrich ML, Shetty G, Dohmae K, Tohda A, Okuyama A, Nishimune Y. 1999. Stimulation of spermatogonial differentiation in juvenile spermatogonial depletion (jsd) mutant mice by gonadotropin-releasing hormone antagonist treatment. Endocrinology 140:4912-4915.
22. Meier-Kriesche HU, Kaplan B. 2001 Immunosuppression in elderly renal transplant recipients: are current regimens too aggressive? Drugs Aging 18:751-759.
23. Neaves WB, Johnson L, Porter JC, Parker Jr CR, Petty CS. 1984. Leydig cell numbers, daily sperm production, and serum gonadotropin levels in aging men. J Clin Endocrinol Metab 59:756-763.
24. Nieschlag E, Lammers U, Freischem CW, Langer K, Wickings EJ. 1982. Reproductive functions in young fathers and grandfathers. J Clin Endocrinol Metab 55:676-681.
25. Ogawa T, Dobrinski I, Avarbock MR, Brinster RL. 1998. Leuprolide, a gonadotropin-releasing hormone agonist, enhances colonization after spermatogonial transplantation into mouse testes. Tissue Cell 30:583-588.
26. Pal L, Santoro N. 2003. Age-related decline in fertility. Endocrinol Metab Clin North Am 32:669-688.
27. Paniagua R, Nistal M, Amat P, Rodriguez MC, Martin A. 1987. Seminiferous tubule involution in elderly men. Biol Reprod 36:939-947.
28. Pelleitier M, Montplaisir S. 1975. The nude mouse: a model of deficient T-cell function. Methods Achiev Exp Pathol 7:149-166.
29. Plas E, Berger P, Hermann M, Pfluger H. 2000. Effects of aging on male fertility? Exp Gerontol 35: 543-551.
30. Ryu BY, Orwig KE, Oatley JM, Avarbock MR, Brinster RL. 2006. Effects of aging and niche microenvironment on spermatogonial stem cell self-renewal. Stem Cells 24:1505-1511.
31. Schoenfeld HA, Hall SJ, Boekelheide K. 2001. Continuously proliferative stem germ cells partially repopulate the aged, atrophic rat testis after gonadotropin-releasing hormone agonist therapy. Biol Reprod 64:1273-1282.
32. Shetty G, Wilson G, Huhtaniemi I, Shuttlesworth GA, Reissmann T, Meistrich ML. 2000. Gonadotropin-releasing hormone analogs stimulate and testosterone inhibits the recovery of spermatogenesis in irradiated rats. Endocrinology 141:1735-1745.
33. Shetty G, Wilson G, Hardy MP, Niu E, Huhtaniemi I, Meistrich ML. 2002. Inhibition of recovery of spermatogenesis in irradiated rats by different androgens. Endocrinology 143:3385-3396.
34. Suzuki N, Withers HR. 1978. Exponential decrease during aging and random lifetime of mouse spermatogonial stem cells. Science 202:1214-1215.
35. Van Steenbrugge GJ, Groen M, de Jong FH, Schroeder FH. 1984. The use of steroid-containing silastic implants in male nude mice: plasma hormone levels and the effect of implantation on the weights of the ventral prostate and seminal vesicles. Prostate 5:639-647.
36. Wang C, Leung A, Sinha Hikim AP. 1993. Reproductive aging in the male brown-Norway rat: a model for the human. Endocrinology 133:2773-2781.
37. Wang C, Sinha Hikim AP, Lue YH, Leung A, Baravarian S, Swerdloff RS. 1999. Reproductive aging in the brown Norway rat is characterized by accelerated germ cell apoptosis and is not altered by luteinizing hormone replacement. J Androl 20:509-518.
38. Wirth-Dzieciolowska E, Czuminska K. 2000. Longevity and aging of mice from lines divergently selected for body weight for over 90 generations. Biogerontology 1:171-178.
39. Zhang X, Ebata KT, Robaire B, Nagano MC. 2006. Aging of male germ line stem cells in mice. Biol Reprod 74:119-124.