Reducing antibody levels in patients undergoing transplantation

New England Journal of Medicine

Volumn 359, Issue 3, 2008, Pages 305-306

  Shapiro, Ron ^a  

^a UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY BLOOD LEVEL; EDITORIAL; IMMUNOSUPPRESSIVE TREATMENT; KIDNEY TRANSPLANTATION; PLASMAPHERESIS; PRIORITY JOURNAL; SENSITIZATION; TRANSPLANTATION; BLOOD; DESENSITIZATION; DRUG COMBINATION; HUMAN; IMMUNOLOGY; METHODOLOGY; NOTE;

ANTIBODY; CD20 ANTIGEN; HLA ANTIGEN; IMMUNOGLOBULIN; IMMUNOLOGIC FACTOR; MONOCLONAL ANTIBODY; RITUXIMAB;

ANTIBODIES; ANTIBODIES, MONOCLONAL; ANTIGENS, CD20; DESENSITIZATION, IMMUNOLOGIC; DRUG THERAPY, COMBINATION; HLA ANTIGENS; HUMANS; IMMUNOGLOBULINS, INTRAVENOUS; IMMUNOLOGIC FACTORS; KIDNEY TRANSPLANTATION;

EID: 47549091427     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJMe0804275     Document Type: Editorial

References (10)

1. Port FK, Wolfe RA, Mauger EA, Berling DP, Jiang K. Comparison of survival probabilities for dialysis patients vs cadaveric renal transplant recipients. JAMA 1993;270:1339-43.
2. Simmons RG, Anderson CR, Kamstra LK. Comparison of quality of life of patients on continuous ambulatory peritoneal dialysis, hemodialysis, and transplantation. Am J Kidney Dis 1984;4:253-5.
3. Andreoni KA, Brayman KL, Guidinger MK, Sommers CM, Sung RS. Kidney and pancreas transplantation in the United States, 1996-2005. Am J Transplant 2007;7:1359-75. [Erratum, Am J Transplant 2007;7:2214.]
4. Montgomery RA, Zachary AA, Racusen LC, et al. Plasmapheresis and intravenous immune globulin provides effective rescue therapy for refractory humoral rejection and allows kidneys to be successfully transplanted into cross-match-positive recipients. Transplantation 2000;70:887-95.
5. Organ Procurement Transplantation Network. Scientific registry of transplant recipients: OPTN: data. (Accessed June 27, 2008, at http://www.optn.org/data/.)
6. Gloor JM, DeGoey SR, Pineda AA, et al. Overcoming a positive crossmatch in living-donor kidney transplantation. Am J Transplant 2003;3:1017-23.
7. Palmer A, Taube D, Welsh K, et al. Extracorporeal immunoadsorption of anti-HLA antibodies: preliminary clinical experience. Transplant Proc 1987;19:3750-1.
8. Jordan SC, Tyan D, Stablein D, et al. Evaluation of intravenous immunoglobulin as an agent to lower allosensitization and improve transplantation in highly sensitized adult patients with end-stage renal disease: report of the NIH IG02 trial. J Am Soc Nephrol 2004;15:3256-62.
9. Vieira CA, Agarwal A, Book BK, et al. Rituximab for reduction of anti-HLA antibodies in patients awaiting renal transplantation. 1. Safety, pharmacodynamics, and pharmacokinetics. Transplantation 2004;77:542-8.
10. Vo AA, Lukovsky M, Toyoda M, et al. Rituximab and intravenous immune globulin for desensitization during renal transplantation. N Engl J Med 2008;359:242-51.