Evaluation of Autofluorescence Imaging with the Scanning Laser Ophthalmoscope and the Fundus Camera in Age-related Geographic Atrophy

American Journal of Ophthalmology

Volumn 146, Issue 2, 2008, Pages 183-192

  Schmitz Valckenberg, Steffen ^a,b,c   Fleckenstein, Monika ^a   Göbel, Arno P ^a   Sehmi, Kulwant ^b   Fitzke, Frederick W ^c   Holz, Frank G ^a   Tufail, Adnan ^b  

^a UNIVERSITY OF BONN   (Germany)

^b MOORFIELDS EYE HOSPITAL   (United Kingdom)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ALGORITHM; ARTICLE; AUTOFLUORESCENCE; CAMERA; CATARACT; CLINICAL ARTICLE; COMPARATIVE STUDY; CONFIDENCE INTERVAL; CONTROLLED STUDY; DIAGNOSTIC IMAGING; DISEASE CLASSIFICATION; DISEASE MARKER; EQUIPMENT; EVALUATION; EXCITATION; HUMAN; IMAGE QUALITY; PRIORITY JOURNAL; RETINA MACULA AGE RELATED DEGENERATION; SCANNING LASER OPHTHALMOSCOPE; SCANNING LASER OPHTHALMOSCOPY; SIGNAL NOISE RATIO;

AGED; AGED, 80 AND OVER; ATROPHY; FEMALE; FLUORESCEIN ANGIOGRAPHY; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; MACULA LUTEA; MACULAR DEGENERATION; MALE; MIDDLE AGED; OPHTHALMOSCOPY; PHOTOGRAPHY; REPRODUCIBILITY OF RESULTS;

EID: 47549087900     PISSN: 00029394     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ajo.2008.04.006     Document Type: Article

References (22)

1. Blair C.J. Geographic atrophy of the retinal pigment epithelium. A manifestation of senile macular degeneration. Arch Ophthalmol 93 (1975) 19-25
2. Sunness J.S. The natural history of geographic atrophy, the advanced atrophic form of age-related macular degeneration. Mol Vis 5 (1999) 25
3. Maguire P., and Vine A.K. Geographic atrophy of the retinal pigment epithelium. Am J Ophthalmol 102 (1986) 621-625
4. Schatz H., and McDonald H.R. Atrophic macular degeneration. Rate of spread of geographic atrophy and visual loss. Ophthalmology 96 (1989) 1541-1551
5. Klein R., Klein B.E., Knudtson M.D., et al. Fifteen-year cumulative incidence of age-related macular degeneration: the Beaver Dam Eye Study. Ophthalmology 114 (2007) 253-262
6. Wang J.J., Rochtchina E., Lee A.J., et al. Ten-year incidence and progression of age-related maculopathy: the Blue Mountains Eye Study. Ophthalmology 114 (2007) 92-98
7. Augood C.A., Vingerling J.R., de Jong P.T., et al. Prevalence of age-related maculopathy in older Europeans: the European Eye Study (EUREYE). Arch Ophthalmol 124 (2006) 529-535
8. Klaver C.C., Wolfs R.C., Vingerling J.R., et al. Age-specific prevalence and causes of blindness and visual impairment in an older population: the Rotterdam Study. Arch Ophthalmol 116 (1998) 653-658
9. Von Ruckmann A., Fitzke F.W., and Bird A.C. Distribution of fundus autofluorescence with a scanning laser ophthalmoscope. Br J Ophthalmol 79 (1995) 407-412
10. Delori F.C., Dorey C.K., Staurenghi G., et al. In vivo fluorescence of the ocular fundus exhibits retinal pigment epithelium lipofuscin characteristics. Invest Ophthalmol Vis Sci 36 (1995) 718-729
11. Holz F.G., Schmitz-Valckenberg S., Spaide R.F., and Bird A.C. Atlas of fundus autofluorescence imaging (2007), Springer, Berlin, Germany 49-53
12. Deckert A., Schmitz-Valckenberg S., Jorzik J., et al. Automated analysis of digital fundus autofluorescence images of geographic atrophy in advanced age-related macular degeneration using confocal scanning laser ophthalmoscopy (cSLO). BMC Ophthalmol 5 (2005) 8
13. Schmitz-Valckenberg S., Jorzik J., Unnebrink K., and Holz F.G. Analysis of digital scanning laser ophthalmoscopy fundus autofluorescence images of geographic atrophy in advanced age-related macular degeneration. Graefes Arch Clin Exp Ophthalmol 240 (2002) 73-78
14. Holz F.G., Bellmann C., Margaritidis M., et al. Patterns of increased in vivo fundus autofluorescence in the junctional zone of geographic atrophy of the retinal pigment epithelium associated with age-related macular degeneration. Graefes Arch Clin Exp Ophthalmol 237 (1999) 145-152
15. Holz F.G., Bellman C., Staudt S., et al. Fundus autofluorescence and development of geographic atrophy in age-related macular degeneration. Invest Ophthalmol Vis Sci 42 (2001) 1051-1056
16. Schmitz-Valckenberg S., Bindewald-Wittich A., Dolar-Szczasny J., et al. Correlation between the area of increased autofluorescence surrounding geographic atrophy and disease progression in patients with AMD. Invest Ophthalmol Vis Sci 47 (2006) 2648-2654
17. Holz F.G., Bindewald-Wittich A., Fleckenstein M., et al. Progression of geographic atrophy and impact of fundus autofluorescence patterns in age-related macular degeneration. Am J Ophthalmol 143 (2007) 463-472
18. Spaide R.F. Fundus autofluorescence and age-related macular degeneration. Ophthalmology 110 (2003) 392-399
19. The Age-Related Eye Disease Study (AREDS) system for classifying cataracts from photographs. AREDS Report No. 4. Am J Ophthalmol 131 (2001) 167-175
20. Bland J.M., and Altman D.G. Measuring agreement in method comparison studies. Stat Methods Med Res 8 (1999) 135-160
21. Bindewald A., Schmitz-Valckenberg S., Jorzik J.J., et al. Classification of abnormal fundus autofluorescence patterns in the junctional zone of geographic atrophy in patients with age-related macular degeneration. Br J Ophthalmol 89 (2005) 874-878
22. Schweitzer D., Schenke S., Hammer M., et al. Towards metabolic mapping of the human retina. Microsc Res Tech 70 (2007) 410-419