Organophosphorus pesticide exposure decreases sperm quality: association between sperm parameters and urinary pesticide levels

Journal of Applied Toxicology

Volumn 28, Issue 5, 2008, Pages 674-680

  Recio Vega, Rogelio ^a   Ocampo Gómez, Guadalupe ^a   Borja Aburto, Victor H ^b   Moran Martínez, Javier ^a   Cebrian Garcia, Mariano E ^c  

^a UNIVERSIDAD AUTÓNOMA DE COAHUILA   (Mexico)

^b INSTITUTO MEXICANO DEL SEGURO SOCIAL   (Mexico)

^c DEPARTAMENTO DE FÍSICA   (Mexico)

Author keywords

Alkyphosphates; Organophosphate pesticides; Organophosphorus pesticides; Semen; Sperm quality

Indexed keywords

ORGANOPHOSPHATE PESTICIDE;

ADULT; ARTICLE; DRUG EFFECT; DRUG EXPOSURE; DRUG URINE LEVEL; FOLLOW UP; GAS LIQUID CHROMATOGRAPHY; HUMAN; LONGITUDINAL STUDY; MALE; MALE GENITAL SYSTEM; OCCUPATIONAL EXPOSURE; PRIORITY JOURNAL; SAMPLE; SEASONAL VARIATION; SPERM; SPERMATOGENESIS; SPERMATOZOON COUNT; SPERMATOZOON DENSITY; TIME; VOLUNTEER; WORKER;

ADOLESCENT; ADULT; AGRICULTURAL WORKERS' DISEASES; BIOTRANSFORMATION; CELL SURVIVAL; ENVIRONMENTAL EXPOSURE; FOLLICLE STIMULATING HORMONE; HUMANS; HYPOTHALAMO-HYPOPHYSEAL SYSTEM; LONGITUDINAL STUDIES; LUTEINIZING HORMONE; MALE; MEXICO; MIDDLE AGED; OCCUPATIONAL EXPOSURE; ORGANOPHOSPHORUS COMPOUNDS; PESTICIDES; SEASONS; SEMEN; SPERM COUNT; SPERM MOTILITY; SPERMATOZOA;

EID: 47549087135     PISSN: 0260437X     EISSN: 10991263     Source Type: Journal    
DOI: 10.1002/jat.1321     Document Type: Article

References (24)

1. Abell A, Ernst E, Bonde JP. 2000. Semen quality and sexual hormones in greenhouse workers. Scand. J. Work Environ. Health 26: 492-500.
2. Andaloz P, Bielsa MA, Andaloz A. 2001. Circannual variation in human semen parameters. Int. J. Androl. 24: 266-271.
3. Aprea C, Sciarra G, Lunghini L. 1996. Analytical method for the determination of urinary alkylphosphates in subjects occupationally exposed to organophosphorus pesticides and in the general population. J. Anal. Toxicol. 20: 559-563.
4. Bustos-Obregon E, Diaz O, Sobarzo C. 2001. Parathion induces mouse germ cells apoptosis. Ital. J. Anat. Embryol. 106 (Suppl 2): 199-204.
5. Bustos-Obregon E, Gonzalez-Hormazabal P. 2003. Effect of a single dose of malathion on spermatogenesis in mice. Asian J. Androl. 2: 105-107.
6. Carlsen E, Petersen JH, Andersson AM, Skakkebaek NE. 2004. Effects of ejaculatory frequency and season on variations in semen quality. Fertil. Steril. 82: 358-366.
7. Chen Z, Godfrey-Baily L, Schiff I, Hauser R. 2004. Impact of seasonal, age and smoking status on human semen parameters: The Massachusetts General Hospital experience. J. Exp. Clin. Assist. Reprod. 1: 2.
8. Chen Z, Toth T, Godfrey-Bailey L, Mercedat N, Schiff I, Hauser R. 2003. Seasonal variation and age-related changes in human semen parameters. J. Androl. 24: 226-231.
9. Contreras HR, Badilla J, Bustos-Obregon E. 1999. Morphofunctional disturbances of human sperm after incubation with organophosphorate pesticides. Biocell 2: 135-141.
10. Contreras HR, Bustos-Obregon E. 1999. Morphological alterations in mouse testis by a single dose of malathion. J. Exp. Zool. 284: 355-359.
11. Debnath D, Mandal TK. 2000. Study of quinalphos (an environmental oestrogenic insecticide) formulation (Ekalux 25 E.C.)-induced damage of the testicular tissues and antioxidant defense systems in Sprague-Dawley albino rats. J. Appl. Toxicol. 3: 197-204.
12. EPA. 1986. Pesticide Assessment Guidelines. Subdivision U, Applicator Exposure Monitoring. U.S. Environmental Protection Agency: Washington, D.C.
13. Gyllenborg J, Skakkebaek NE, Nielsen NC, Keiding N, Giwercman A. 1999. Secular and seasonal changes in semen quality among young Danish men: a statistical analysis of semen samples from 1927 donor candidates during 1977-1995. Int. J. Androl. 22: 28-36.
14. Harrison PT, Homes P, Humfey CD. 1997. Reproductive health in humans and wildlife: adverse trends associated with environment chemical exposure. Sci. Total Environ. 205: 97-106.
15. Kamijima M, Hibi H, Taki K, Saito I, Wang H, Itohara S, Yamada T, Ichihara G, Shibata E, Nakajima T, Takeuchi YA. 2004. Survey of semen indices in insecticide sprayers. J. Occup. Health 46: 109-118.
16. Larsen SB, Spano M, Giwercman A, Bonde JP. 1999. A longitudinal study of semen quality in pesticide spraying Danish farmers. ASCLEPIOS Study Group. Occup. Environ. Med. 56: 139-144.
17. Mallidis C, Howard EJ, Baker HW. 1991. Variation of semen quality in normal men. Int. J. Androl. 2: 99-107.
18. Meeker JD, Barr DB, Ryan L, Herrick RF, Bennett DH, Bravo R, Hauser R. 2005. Temporal variability of urinary levels of nonpersistent insecticides in adult men. J. Expo. Anal. Environ. Epidemiol. 15: 271-281.
19. O'Rourke MK, Lizardi PS, Rogan SP, Freeman NC, Aguirre A, Saint CG. 2000. Pesticide exposure and creatinine variation among young children. J. Expo. Anal. Environ. Epidemiol. 10: 672-681.
20. Padungtod C, Savitz DA, Overstreet JW, Christiani DC, Ryan LM, Xu X. 2000. Occupational pesticide exposure and semen quality among Chinese workers. J. Occup. Environ. Med. 10: 982-992.
21. Recio R, Ocampo-Gomez G, Moran-Martinez J, Borja-Aburto VH, Lopez M, Uribe M, Gomez-Muñoz A, Cebrian ME. 2005. Pesticide exposure alters follicle-stimulating hormone levels in Mexican agricultural workers. Environ. Health Perspect. 113: 1160-1163.
22. Rodriguez H, Bustos-Obregon E. 2000. An in vitro model to evaluate the effect of an organophosphoric agropesticide on cell proliferation in mouse seminiferous tubules. Andrologia 1: 1-5.
23. Strohmer H, Boldizsar A, Plockinger B, Feldner Butzin M, Feitchinger W. 1993. Agricultural work and male infertility. Am. J. Ind. Med. 24: 587-592.
24. WHO. 1992. Laboratory Manual for the Examination of Human Semen and Semen - Cervical Mucus Interaction. Cambridge University Press: Cambridge, UK.