Insights from a whole cystectomy specimen-association of primary small cell carcinoma of the bladder with transitional cell carcinoma in situ

Human Pathology

Volumn 39, Issue 8, 2008, Pages 1258-1262

  Gaisa, Nadine Therese ^a   Tilki, Derya ^b   Losen, Inge ^a   Dahl, Edgar ^a   Stoehr, Robert ^c   Stief, Christian Georg ^b   Knüchel, Ruth ^a  

^a RWTH AACHEN UNIVERSITY   (Germany)

^b LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^c UNIVERSITY HOSPITAL ERLANGEN   (Germany)

Author keywords

Small cell carcinoma of the urinary bladder; TP53; Transitional cell carcinoma in situ

Indexed keywords

CD44V6 ANTIGEN; CD56 ANTIGEN; CHROMOGRANIN A; NEURON SPECIFIC ENOLASE; PROTEIN P53; SYNAPTOPHYSIN; THYROID TRANSCRIPTION FACTOR 1;

AGED; ARTICLE; BLADDER CARCINOMA; CARCINOMA IN SITU; CASE REPORT; CYSTECTOMY; HETEROZYGOSITY LOSS; HUMAN; IMMUNOHISTOCHEMISTRY; MALE; MICROSATELLITE MARKER; MUTATION; POINT MUTATION; SMALL CELL CARCINOMA; TRANSITIONAL CELL CARCINOMA;

AGED, 80 AND OVER; CARCINOMA IN SITU; CARCINOMA, SMALL CELL; CARCINOMA, TRANSITIONAL CELL; CYSTECTOMY; HUMANS; IMMUNOHISTOCHEMISTRY; LOSS OF HETEROZYGOSITY; MALE; MUTATION; POINT MUTATION; TUMOR SUPPRESSOR PROTEIN P53; URINARY BLADDER; URINARY BLADDER NEOPLASMS;

EID: 47549086671     PISSN: 00468177     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.humpath.2007.12.017     Document Type: Article

References (8)

1. Cheng L., Pan C.X., Yang X.J., et al. Small cell carcinoma of the urinary bladder: a clinicopathologic analysis of 64 patients. Cancer 101 (2004) 957-962
2. Sved P., Gomez P., Manoharan M., Civantos F., and Soloway M.S. Small cell carcinoma of the bladder. BJU Int 94 (2004) 12-17
3. Smith A. Neurosecretory cells in carcinoma in situ of the urinary bladder-an incidental finding. Ultrastruct Pathol 8 (1985) 267
4. Fetissof F., Dubois M.P., Arbeille-Brassart B., Lanson Y., Boivin F., and Jobard P. Endocrine cells in the prostate gland, urothelium and Brenner tumors. Immunohistological and ultrastructural studies. Virchows Arch B Cell Pathol Incl Mol Pathol 42 (1983) 53-64
5. Trias I., Algaba F., Condom E., et al. Small cell carcinoma of the urinary bladder. Presentation of 23 cases and review of 134 published cases. Eur Urol 39 (2001) 85-90
6. Stoehr R., Zietz S., Burger M., et al. Deletions of chromosomes 9 and 8p in histologically normal urothelium in patients with bladder cancer. Eur Urol 47 (2005) 58-63
7. Cheng L., Jones T.D., McCarthy R.P., et al. Molecular genetic evidence for a common clonal origin of urinary bladder small cell carcinoma and co-existing urothelial carcinoma. Am J Pathol 166 (2005) 1533-1539
8. Terracciano L., Richter J., Tornillo L., et al. Chromosomal imbalances in small cell carcinomas of the urinary bladder. J Pathol 189 (1999) 230-235