-
1
-
-
0035805528
-
Regulation of membrane targeting of the G protein-coupled receptor kinase 2 by protein kinase A and its anchoring protein akap79
-
Cong M, Perry SJ, Lin FT, Fraser I D, Hu LA, Chen W, Pitcher JA, Scott JD, Lefkowitz RJ. 2001. Regulation of membrane targeting of the G protein-coupled receptor kinase 2 by protein kinase A and its anchoring protein akap79. J Biol Chem 276: 15192-9.
-
(2001)
J Biol Chem
, vol.276
, pp. 15192-15199
-
-
Cong, M.1
Perry, S.J.2
Lin, F.T.3
Fraser, I.D.4
Hu, L.A.5
Chen, W.6
Pitcher, J.A.7
Scott, J.D.8
Lefkowitz, R.J.9
-
2
-
-
33947424807
-
Stop that cell! Beta-arrestin-dependent chemotaxis: A tale of localized actin assembly and receptor desensitization
-
Defea KA. 2007. Stop that cell! Beta-arrestin-dependent chemotaxis: a tale of localized actin assembly and receptor desensitization. Annu Rev Physiol 69:535-60.
-
(2007)
Annu Rev Physiol
, vol.69
, pp. 535-560
-
-
Defea, K.A.1
-
3
-
-
0034111097
-
Agonist-dependent modulation of G protein-coupled receptor kinase 2 by mitogen-activated protein kinases
-
Elorza A, Sarnago S, Mayor Jr F. 2000. Agonist-dependent modulation of G protein-coupled receptor kinase 2 by mitogen-activated protein kinases. Mol Pharmacol 57:778-83.
-
(2000)
Mol Pharmacol
, vol.57
, pp. 778-783
-
-
Elorza, A.1
Sarnago, S.2
Mayor Jr, F.3
-
4
-
-
0042707658
-
Mapk-dependent degradation of g protein-coupled receptor kinase 2
-
Elorza A, Penela P, Sarnago S, Mayor Jr F. 2003. Mapk-dependent degradation of g protein-coupled receptor kinase 2. J Biol Chem 278:29164-73.
-
(2003)
J Biol Chem
, vol.278
, pp. 29164-29173
-
-
Elorza, A.1
Penela, P.2
Sarnago, S.3
Mayor Jr, F.4
-
5
-
-
33646705915
-
The multi-functional git family of proteins
-
Hoefen RJ, Berk BC. 2006. The multi-functional git family of proteins. J Cell Sci 119:1469-75.
-
(2006)
J Cell Sci
, vol.119
, pp. 1469-1475
-
-
Hoefen, R.J.1
Berk, B.C.2
-
6
-
-
30044434455
-
G protein-coupled receptor kinase 2 negatively regulates chemokine signaling at a level downstream from g protein subunits
-
Jimenez-Sáinz MC, Murga C, Kavelaars A, Jurado-Pueyo M, Krakstad BF, Heijnen CJ, Mayor Jr F, Aragay AM. 2006. G protein-coupled receptor kinase 2 negatively regulates chemokine signaling at a level downstream from g protein subunits. Mol Biol Cell 17:25-31.
-
(2006)
Mol Biol Cell
, vol.17
, pp. 25-31
-
-
Jimenez-Sáinz, M.C.1
Murga, C.2
Kavelaars, A.3
Jurado-Pueyo, M.4
Krakstad, B.F.5
Heijnen, C.J.6
Mayor Jr, F.7
Aragay, A.M.8
-
7
-
-
0035910399
-
Phosphorylation of GRK2 by protein kinase c abolishes its inhibition by calmodulin
-
Krasel C, Dammeier S, Winstel R, Brockmann J, Mischak H, Lohse MJ. 2001. Phosphorylation of GRK2 by protein kinase c abolishes its inhibition by calmodulin. J Biol Chem 276:1911-15.
-
(2001)
J Biol Chem
, vol.276
, pp. 1911-1915
-
-
Krasel, C.1
Dammeier, S.2
Winstel, R.3
Brockmann, J.4
Mischak, H.5
Lohse, M.J.6
-
8
-
-
0142026209
-
P38 map kinases: Key signalling molecules as therapeutic targets for inflammatory diseases
-
Kumar S, Boehm J, Lee JC. 2003. P38 map kinases: key signalling molecules as therapeutic targets for inflammatory diseases. Nat Rev Drug Discov 2:717-26.
-
(2003)
Nat Rev Drug Discov
, vol.2
, pp. 717-726
-
-
Kumar, S.1
Boehm, J.2
Lee, J.C.3
-
9
-
-
33947198179
-
Lymphocyte G-protein-coupled receptor kinase-2 is upregulated in patients with Alzheimer's disease
-
Leosco D, Fortunato F, Rengo G, Iaccarino G, Sanzari E, Golino L, Zincarelli C, Canonico V, Marchese M, Koch WJ, Rengo F. 2007. Lymphocyte G-protein-coupled receptor kinase-2 is upregulated in patients with Alzheimer's disease. Neurosci Lett 415:279-82.
-
(2007)
Neurosci Lett
, vol.415
, pp. 279-282
-
-
Leosco, D.1
Fortunato, F.2
Rengo, G.3
Iaccarino, G.4
Sanzari, E.5
Golino, L.6
Zincarelli, C.7
Canonico, V.8
Marchese, M.9
Koch, W.J.10
Rengo, F.11
-
10
-
-
0036070773
-
Oxidative stress decreases G protein-coupled receptor kinase 2 in lymphocytes via a calpain-dependent mechanism
-
Lombardi MS, Kavelaars A, Penela P, Scholtens EJ, Roccio M, Schmidt RE, Schedlowski M, Mayor Jr F, Heijnen CJ. 2002. Oxidative stress decreases G protein-coupled receptor kinase 2 in lymphocytes via a calpain-dependent mechanism. Mol Pharmacol 62:379-88.
-
(2002)
Mol Pharmacol
, vol.62
, pp. 379-388
-
-
Lombardi, M.S.1
Kavelaars, A.2
Penela, P.3
Scholtens, E.J.4
Roccio, M.5
Schmidt, R.E.6
Schedlowski, M.7
Mayor Jr, F.8
Heijnen, C.J.9
-
11
-
-
0032919035
-
Decreased expression and activity of G-protein-coupled receptor kinases in peripheral blood mononuclear cells of patients with rheumatoid arthritis
-
Lombardi MS, Kavelaars A, Schedlowski M, Bijlsma JW, Okihara KL, Van de Pol M, Ochsmann S, Pawlak C, Schmidt RE, Heijnen CJ. 1999. Decreased expression and activity of G-protein-coupled receptor kinases in peripheral blood mononuclear cells of patients with rheumatoid arthritis. FASEB J 13: 715-25.
-
(1999)
FASEB J
, vol.13
, pp. 715-725
-
-
Lombardi, M.S.1
Kavelaars, A.2
Schedlowski, M.3
Bijlsma, J.W.4
Okihara, K.L.5
Van de Pol, M.6
Ochsmann, S.7
Pawlak, C.8
Schmidt, R.E.9
Heijnen, C.J.10
-
12
-
-
0035253491
-
Adjuvant arthritis induces down-regulation of G protein-coupled receptor kinases in the immune system
-
Lombardi MS, Kavelaars A, Cobelens PM, Schmidt RE, Schedlowski M, Heijnen CJ. 2001. Adjuvant arthritis induces down-regulation of G protein-coupled receptor kinases in the immune system. J Immunol 166:1635-40.
-
(2001)
J Immunol
, vol.166
, pp. 1635-1640
-
-
Lombardi, M.S.1
Kavelaars, A.2
Cobelens, P.M.3
Schmidt, R.E.4
Schedlowski, M.5
Heijnen, C.J.6
-
13
-
-
1842523247
-
Hypoxia/ischemia modulates G protein-coupled receptor kinase 2 and beta-arrestin-1 levels in the neonatal rat brain
-
Lombardi MS, Van den Tweel E, Kavelaars A, Groenendaal F, Van bel F, Heijnen, CJ. 2004. Hypoxia/ischemia modulates G protein-coupled receptor kinase 2 and beta-arrestin-1 levels in the neonatal rat brain. Stroke 35:981-6.
-
(2004)
Stroke
, vol.35
, pp. 981-986
-
-
Lombardi, M.S.1
Van den Tweel, E.2
Kavelaars, A.3
Groenendaal, F.4
Van bel, F.5
Heijnen, C.J.6
-
14
-
-
33749426526
-
Tyrosine phosphorylation of G-protein-coupled-receptor kinase 2 (GRK2) by c-src modulates its interaction with galphaq
-
Mariggio S, Garcia-Hoz C, Sarnago S, De Blasi A, Mayor Jr F, Ribas C. 2006. Tyrosine phosphorylation of G-protein-coupled-receptor kinase 2 (GRK2) by c-src modulates its interaction with galphaq. Cell Signal 18:2004-12.
-
(2006)
Cell Signal
, vol.18
, pp. 2004-2012
-
-
Mariggio, S.1
Garcia-Hoz, C.2
Sarnago, S.3
De Blasi, A.4
Mayor Jr, F.5
Ribas, C.6
-
15
-
-
0035903669
-
Beta-arrestin- and c-src-dependent degradation of G-protein-coupled receptor kinase 2
-
Penela P, Elorza A, Sarnago S, Mayor Jr F. 2001. Beta-arrestin- and c-src-dependent degradation of G-protein-coupled receptor kinase 2. EMBO J 20:5129-38.
-
(2001)
EMBO J
, vol.20
, pp. 5129-5138
-
-
Penela, P.1
Elorza, A.2
Sarnago, S.3
Mayor Jr, F.4
-
16
-
-
29144497998
-
Mechanisms of regulation of G protein-coupled receptor kinases GRKs and cardiovascular disease
-
Penela P, Murga C, Ribas C, Tutor AS, Peregrin S, Mayor Jr F. 2006. Mechanisms of regulation of G protein-coupled receptor kinases GRKs and cardiovascular disease. Cardiovasc Res 69:46-56.
-
(2006)
Cardiovasc Res
, vol.69
, pp. 46-56
-
-
Penela, P.1
Murga, C.2
Ribas, C.3
Tutor, A.S.4
Peregrin, S.5
Mayor Jr, F.6
-
17
-
-
0141629679
-
Mechanisms of regulation of the expression and function of G protein-coupled receptor kinases
-
Penela P, Ribas C, Mayor Jr F. 2003. Mechanisms of regulation of the expression and function of G protein-coupled receptor kinases. Cell Signal 15: 973-81.
-
(2003)
Cell Signal
, vol.15
, pp. 973-981
-
-
Penela, P.1
Ribas, C.2
Mayor Jr, F.3
-
18
-
-
0032567351
-
Degradation of the g protein-coupled receptor kinase 2 by the proteasome pathway
-
Penela P, Ruiz-Gómez A, Castaño, JG, Mayor Jr F. 1998. Degradation of the g protein-coupled receptor kinase 2 by the proteasome pathway. J Biol Chem 273:35238-44.
-
(1998)
J Biol Chem
, vol.273
, pp. 35238-35244
-
-
Penela, P.1
Ruiz-Gómez, A.2
Castaño, J.G.3
Mayor Jr, F.4
-
19
-
-
33750218229
-
Phosphorylation of p38 by GRK2 at the docking groove unveils a novel mechanism for inactivating p38mapk
-
Peregrin S, Jurado-Pueyo M, Campos PM, Sanz-Moreno V, Ruiz-Gomez A, Crespo P, Mayor Jr F, Murga C. 2006. Phosphorylation of p38 by GRK2 at the docking groove unveils a novel mechanism for inactivating p38mapk. Curr Biol 16: 2042-7.
-
(2006)
Curr Biol
, vol.16
, pp. 2042-2047
-
-
Peregrin, S.1
Jurado-Pueyo, M.2
Campos, P.M.3
Sanz-Moreno, V.4
Ruiz-Gomez, A.5
Crespo, P.6
Mayor Jr, F.7
Murga, C.8
-
20
-
-
0033521109
-
Feedback inhibition of g protein-coupled receptor kinase 2 (GRK2) activity by extracellular signal-regulated kinases
-
Pitcher JA, Tesmer JJ, Freeman JL, Capel WD, Stone WC, Lefkowitz RJ. 1999. Feedback inhibition of g protein-coupled receptor kinase 2 (GRK2) activity by extracellular signal-regulated kinases. J Biol Chem 274:34531-4.
-
(1999)
J Biol Chem
, vol.274
, pp. 34531-34534
-
-
Pitcher, J.A.1
Tesmer, J.J.2
Freeman, J.L.3
Capel, W.D.4
Stone, W.C.5
Lefkowitz, R.J.6
-
21
-
-
0034595227
-
Analysis of the human g protein-coupled receptor kinase 2 (GRK2) gene promoter: Regulation by signal transduction systems in aortic smooth muscle cells
-
Ramos-Ruiz R, Penela P, Penn R.B, Mayor Jr F. 2000. Analysis of the human g protein-coupled receptor kinase 2 (GRK2) gene promoter: regulation by signal transduction systems in aortic smooth muscle cells. Circulation 101:2083-9.
-
(2000)
Circulation
, vol.101
, pp. 2083-2089
-
-
Ramos-Ruiz, R.1
Penela, P.2
Penn, R.B.3
Mayor Jr, F.4
-
22
-
-
33947424008
-
The G protein-coupled receptor kinase (GRK) interactome: Role of GRKs in GPCR regulation and signaling
-
Ribas C, Penela P, Murga C, Salcedo A, Garcia-Hoz C, Jurado-Pueyo M, Aymerich, I, Mayor Jr F. 2007. The G protein-coupled receptor kinase (GRK) interactome: role of GRKs in GPCR regulation and signaling. Biochim Biophys Acta 1768:913-22.
-
(2007)
Biochim Biophys Acta
, vol.1768
, pp. 913-922
-
-
Ribas, C.1
Penela, P.2
Murga, C.3
Salcedo, A.4
Garcia-Hoz, C.5
Jurado-Pueyo, M.6
Aymerich, I.7
Mayor Jr, F.8
-
23
-
-
0344305784
-
Cell migration: Integrating signals from front to back
-
Ridley AJ, Schwartz MA, Burridge K, Firtel RA, Ginsberg MH, Borisy G, Parsons, JT, Horwitz AR. 2003. Cell migration: integrating signals from front to back. Science 302: 1704-9.
-
(2003)
Science
, vol.302
, pp. 1704-1709
-
-
Ridley, A.J.1
Schwartz, M.A.2
Burridge, K.3
Firtel, R.A.4
Ginsberg, M.H.5
Borisy, G.6
Parsons, J.T.7
Horwitz, A.R.8
-
24
-
-
33750208522
-
Mdm2 is involved in the ubiquitination and degradation of G-protein-coupled receptor kinase 2
-
Salcedo A, Mayor Jr F, Penela P. 2006. Mdm2 is involved in the ubiquitination and degradation of G-protein-coupled receptor kinase 2. EMBO J 25:4752-62.
-
(2006)
EMBO J
, vol.25
, pp. 4752-4762
-
-
Salcedo, A.1
Mayor Jr, F.2
Penela, P.3
-
25
-
-
0033607513
-
Agonist-dependent phosphorylation of the G protein-coupled receptor kinase 2 (GRK2) by src tyrosine kinase
-
Sarnago S, Elorza A, Mayor Jr F. 1999. Agonist-dependent phosphorylation of the G protein-coupled receptor kinase 2 (GRK2) by src tyrosine kinase. J Biol Chem 274: 34411-16.
-
(1999)
J Biol Chem
, vol.274
, pp. 34411-34416
-
-
Sarnago, S.1
Elorza, A.2
Mayor Jr, F.3
-
26
-
-
0036569034
-
Sphingosine 1-phosphate signaling: Providing cells with a sense of direction
-
Spiegel S, English D, Milstien S. 2002. Sphingosine 1-phosphate signaling: providing cells with a sense of direction. Trends Cell Biol 12: 236-42.
-
(2002)
Trends Cell Biol
, vol.12
, pp. 236-242
-
-
Spiegel, S.1
English, D.2
Milstien, S.3
-
27
-
-
33845412884
-
GRKs and arrestins: Regulators of migration and inflammation
-
Vroon A, Heijnen CJ, Kavelaars A. 2006. GRKs and arrestins: regulators of migration and inflammation. J Leukoc Biol 80:1214-21.
-
(2006)
J Leukoc Biol
, vol.80
, pp. 1214-1221
-
-
Vroon, A.1
Heijnen, C.J.2
Kavelaars, A.3
-
28
-
-
2342519446
-
Reduced GRK2 level in t cells potentiates chemotaxis and signaling in response to CCl4
-
Vroon A, Heijnen CJ, Lombardi MS, Cobelens PM, Mayor Jr F, Caron MG, Kavelaars A. 2004. Reduced GRK2 level in t cells potentiates chemotaxis and signaling in response to CCl4. J Leukoc Biol 75:901-9.
-
(2004)
J Leukoc Biol
, vol.75
, pp. 901-909
-
-
Vroon, A.1
Heijnen, C.J.2
Lombardi, M.S.3
Cobelens, P.M.4
Mayor Jr, F.5
Caron, M.G.6
Kavelaars, A.7
-
29
-
-
15444372618
-
G protein-coupled receptor kinase 2 in multiple sclerosis and experimental autoimmune encephalomyelitis
-
Vroon A, Kavelaars A, Limmroth V, Lombardi MS, Goebel MU, Van dam AM, Caron MG, Schedlowski M, Heijnen CJ. 2005. G protein-coupled receptor kinase 2 in multiple sclerosis and experimental autoimmune encephalomyelitis. J Immunol 174:4400-6.
-
(2005)
J Immunol
, vol.174
, pp. 4400-4406
-
-
Vroon, A.1
Kavelaars, A.2
Limmroth, V.3
Lombardi, M.S.4
Goebel, M.U.5
Van dam, A.M.6
Caron, M.G.7
Schedlowski, M.8
Heijnen, C.J.9
|