2-(2-(dimethylaminomethyl)phenoxy)-5-iodophenylamine: An improved serotonin transporter imaging agent

Journal of Medicinal Chemistry

Volumn 47, Issue 21, 2004, Pages 5258-5264

  Kung, Hank F ^a   Newman, Suzanne ^a   Choi, Seok Rye ^a   Oya, Shunichi ^a   Hou, Catherine ^a   Zhuang, Zhi Ping ^a   Acton, Paul D ^a   Plössl, Karl ^a   Winkler, Jeffrey ^a   Kung, Mei Ping ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 [2 (DIMETHYLAMINOMETHYL)BENZYL] 5 IODOPHENYLAMINE; 2 [2 (DIMETHYLAMINOMETHYL)BENZYL] 5 IODOPHENYLAMINE I 125; 2 [2 (DIMETHYLAMINOMETHYL)PHENOXY] 5 IODOPHENYLAMINE; 2 [2 (DIMETHYLAMINOMETHYL)PHENOXY] 5 IODOPHENYLAMINE I 123; 2 [2 (DIMETHYLAMINOMETHYL)PHENOXY] 5 IODOPHENYLAMINE I 125; ESCITALOPRAM; KETANSERIN; METHYLPHENIDATE; NISOXETINE; RACLOPRIDE; SEROTONIN TRANSPORTER; TRACER; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTORADIOGRAPHY; BINDING AFFINITY; BINDING SITE; BRAIN REGION; CEREBELLUM; CONTROLLED STUDY; DIAGNOSTIC IMAGING; DRUG BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; EX VIVO STUDY; HYPOTHALAMUS; IN VIVO STUDY; ISOTOPE LABELING; NONHUMAN; PROTEIN LOCALIZATION; PROTEIN TRANSPORT; RAT; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; TISSUE SECTION;

ANILINE COMPOUNDS; ANIMALS; AUTORADIOGRAPHY; BENZYLAMINES; BRAIN; CARRIER PROTEINS; CELL LINE; IODINE RADIOISOTOPES; ISOTOPE LABELING; MEMBRANE GLYCOPROTEINS; MEMBRANE TRANSPORT PROTEINS; NERVE TISSUE PROTEINS; RADIOLIGAND ASSAY; RADIOPHARMACEUTICALS; RATS; SEROTONIN; SEROTONIN PLASMA MEMBRANE TRANSPORT PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP; TISSUE DISTRIBUTION; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON;

EID: 4744351075     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm049917p     Document Type: Article

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