Dicumarol, an inhibitor of ADP-ribosylation of CtBP3/BARS, fragments Golgi non-compact tubular zones and inhibits intra-Golgi transport

European Journal of Cell Biology

Volumn 83, Issue 6, 2004, Pages 263-279

  Mironov, Alexander A ^a   Colanzi, Antonino ^a   Polishchuk, Roman S ^a   Beznoussenko, Galina V ^a   Mironov Jr , Alexander A ^a   Fusella, Aurora ^a   Di Tullio, Giuseppe ^a   Silletta, Maria Giuseppina ^a   Corda, Daniela ^a   De Matteis, Maria Antonietta ^a   Luini, Alberto ^a  

^a MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH   (Italy)

Author keywords

Dicumarol; Golgi; Transport; Tubules; Vesicles

Indexed keywords

ADENOSINE DIPHOSPHATE RIBOSYLATION FACTOR; CARRIER PROTEIN; CELL PROTEIN; COAT PROTEIN; DICOUMAROL; GALACTOSYLTRANSFERASE; GREEN FLUORESCENT PROTEIN;

ADENOSINE DIPHOSPHATE RIBOSYLATION; ANIMAL CELL; ARTICLE; CELL PERMEABILIZATION; CELL SIZE; CELL STRUCTURE; CELL SURFACE; CELL VACUOLE; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; GOLGI COMPLEX; INTRACELLULAR TRANSPORT; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN MODIFICATION; PROTEIN TRANSPORT; STRUCTURE ANALYSIS; TRANS GOLGI NETWORK;

ANIMALIA;

EID: 4744350138     PISSN: 01719335     EISSN: None     Source Type: Journal    
DOI: 10.1078/0171-9335-00377     Document Type: Article

References (43)

1. Banta, M., Polizotto R. S., Wood S. A., de Figueiredo P., Brown W. J., 1995. Characterization of a cytosolic activity that induces the formation of Golgi membrane tubules in a cell-free reconstitution system. Biochemistry. 34, 13359-13366.
2. Beznoussenko G. V., Mironov A. A., 2002. Models of intracellular transport and evolution of the Golgi complex. Anat. Rec. 268, 226-238.
3. Bonfanti, L., Mironov, A. A. Jr., Martinez-Menarguez J. A., Martella O., Fusella A., Baldassarre M., Buccione R., Geuze H. J., Mironov A. A., Luini A., 1998. Procollagen traverses the Golgi stack without leaving the lumen of cisternae: evidence for cisternal maturation. Cell 95, 993-1003.
4. Brown, W. J., Farquhar M. G., 1989. Immunoperoxidase methods for the localization of antigens in cultured cells and tissue sections by electron microscopy. Methods Cell Biol. 32, 553-567.
5. Buccione, R., Bannykh, S., Santone, I., Baldassarre, M., Facchiano, F., Bozzi Y., Di Tullio, G., Mironov, A. A., Luini, A., De Matteis, M. A., 1996. Regulation of constitutive exocytic transport by membrane receptors. A biochemical and morphometric study. J. Biol. Chem. 271, 3523-3533.
6. Cole, N. B., Sciaky, N., Marotta, A., Song, J., Lippincott-Schwartz, J., 1996a. Golgi dispersal during microtubule disruption: regeneration of Golgi stacks at peripheral endoplasmic reticulum exit sites. Mol. Biol. Cell 7, 631-650.
7. Cole, N. B., Smith, C. L., Sciaky, M., Terasaki, M., Edidin, M., Lippincott-Schwartz, J., 1996b. Diffusion mobility of Golgi proteins in membranes of living cells. Science 273, 797-801.
8. Connolly, C. N., Futter, C. E., Gibson, A., Hopkins, C. R., Cutler, D. F., 1994. Transport into and out of the Golgi complex studied by transfecting cells with cDNAs encoding horseradish peroxidase. J. Cell Biol. 127, 641-652.
9. Cooper, M. S., Cornell-Bell, A. H., Chernjavsky, A., Dani, J. W., Smith, S. J., 1990. Tubulovesicular processes emerge from trans-Golgi cisternae, extend along microtubules, and interlink adjacent trans-Golgi elements into a reticulum. Cell. 61, 135-145.
10. 2 antagonists. Mol. Biol. Cell 10, 1763-1782.
11. De Matteis, M. A., Santini, G., Kahn, R. A., DiTullio, G., Luini, A., 1993. Receptor and protein kinase C-mediated regulation of ARF binding to the Golgi complex. Nature 364, 818-821.
12. De Matteis, M. A., Di Girolamo, M., Colanzi, A., Pallas, M., Di Tullio, G., McDonald, L. J., Moss, J., Santini, G., Bannykh, S., Corda, D., Luini, A., 1994. Stimulation of endogenous ADP-ribosylation by brefeldin A. Proc. Natl. Acad. Sci. USA 91, 1114-1118.
13. Di Girolamo, M., Silletta, M. G., De Matteis, M. A., Braca, A., Colanzi, A., Pawlak, D., Rasenick, M. M., Luini, A., Corda, D., 1995. Evidence that the 50-kDa substrate of brefeldin A-dependent ADP-ribosylation binds GTP and is modulated by the G-protein β subunit complex. Proc. Natl. Acad. Sci. USA 92, 7065-7069.
14. Hauri, H. P., Kappeler, F., Andersson, H., Appenzeller, C., 2000. ERGIC-53 and traffic in the secretory pathway. J Cell Sci. 113, 587-596.
15. Heuser, J. E., Reese, T. S., Dennis, M. J., Jan, Y., Jan, L., Evans, L., 1979. Synaptic vesicle exocytosis captured by quick freezing and correlated with quantal transmitter release. J. Cell Biol. 81, 275-300.
16. Klausner, R. D., Donaldson, J. G., Lippincott-Schwartz, J., 1992. Brefeldin A: insights into the control of membrane traffic and organelle structure. J. Cell Biol. 116, 1071-1080.
17. Ladinsky, M. S., Mastronarde, D. N., McIntosh, J. R., Howell, K. E., Staehelin, L. A., 1999. Golgi structure in three dimensions: functional insights from the normal rat kidney cell. J. Cell Biol. 144, 1135-1149.
18. Lahtinen, U., Hellman, U., Wernstedt, C., Saraste, J., Pettersson, R. F., 1996. Molecular cloning and expression of a 58-kDa cis-Golgi and intermediate compartment protein. J. Biol. Chem. 271, 4031-4037.
19. Leblond, C. P., 1989. Synthesis and secretion of collagen by cells of connective tissue, bone, and dentin. Anat. Rec. 224, 123-138.
20. Liljedahl, M., Maeda, Y., Colanzi, A., Ayala, I., Van Lint, J., Malhotra V., 2001. Protein kinase D regulates the fission of cell surface destined transport carriers from the trans-Golgi network. Cell 104, 409-420.
21. Lindsey, J. D., Ellisman, M. H., 1985. The neuronal endomembrane system. I. Direct links between rough endoplasmic reticulum and the cis element of the Golgi apparatus. J. Neurosci. 5, 3111-3123.
22. Lippincott-Schwartz, J., Yuan, L. C., Bonifacino, J. S., Klausner, R. D., 1989. Rapid redistribution of Golgi proteins into the ER in cells treated with Brefeldin A: evidence for membrane cycling from Golgi to ER. Cell 56, 801-813.
23. Marsh, B. J., Howell, K. E., 2002. The mammalian Golgi - complex debates. Nat. Rev. Mol. Cell. Biol. 3, 789-795.
24. + and ADP-ribosylation in the maintenance of the Golgi structure. J. Cell Biol. 139, 1109-1118.
25. Mironov, A. A. Jr., Mironov, A. A., 1998. Estimation of subcellular organelle volume from ultrathin sections through centrioles with a discretized version of vertical rotator. J. Microsc. 192, 29-36.
26. Mironov, A. A. Jr., Luini A., Mironov, A. A., 1998. A synthetic model of intra-Golgi traffic. FASEB J. 12, 249-252.
27. Mironov, A. A., Beznoussenko, G. V., Nicoziani, P., Martella, O., Trucco, A., Kweon, H.-S., Di Giandomenico, D., Polishchuk, R. S., Fusella, A., Lupetti, P., Berger, E. G., Geerts, W. J., Koster, A. J., Burger, K. N., Luini, A., 2001. Small cargo proteins and large aggregates can traverse the Golgi by a common mechanism without leaving the lumen of cisternae. J. Cell Biol. 155, 1225-1238.
28. Misteli, T., Warren, G., 1995. Mitotic disassembly of the Golgi apparatus in vivo. J. Cell Sci. 108, 2715 -2727.
29. Orci, L., Tagaya, M., Amherdt, M., Perrelet, A., Donaldson, J. G., Lippincott-Schwartz, J., Klausner, R. D., Rothman, J. E., 1991. Brefeldin A, a drug that blocks secretion, prevents the assembly of non-clathrin-coated buds on Golgi cisternae. Cell 64, 1183-1195.
30. Pavelka, M., Ellinger, A., 1993. Early and late transformations occurring at organelles of the Golgi area under the influence of brefeldin A: an ultrastructural and lectin cytochemical study. J. Histochem. Cytochem. 41, 1031-1042.
31. Polishchuk, E. V., Di Pentima, A., Luini, A., Polishchuk, R. S., 2003. Mechanism of constitutive export from the Golgi: bulk flow via the formation, protrusion and en bloc cleavage of large TGN tubular domains. Mol. Biol. Cell 14, 4470-4485.
32. Rambourg, A., Clermont, Y., 1990. Three-dimensional electron microscopy: structure of the Golgi apparatus. Eur. J. Cell Biol. 51, 189-200.
33. Sariola, M., Saraste, J., Kuismanen, E., 1995. Communication of post-Golgi elements with early endocytic pathway: regulation of endoproteolytic cleavage of Semliki Forest virus p62 precursor. J. Cell Sci. 108, 2465-2475.
34. Sciaky, N., Presley, J., Smith, C., Zaal, K. J. M., Cole, N., Moreira, J. E., Terasaki, M., Siggia, E., Lippincott-Schwartz, J., 1997. Golgi tubule traffic and the effects of brefeldin A visualized in living cells. J. Cell Biol. 139, 1137-1155.
35. Spanò, S., Silletta, M. G., Colanzi, A., Alberti, S., Fiucci, G., Valente, C., Fusella, A., Salmona, M., Mironov, A. A., Luini, A., Corda, D., 1999. Molecular cloning and functional characterization of brefeldin A ADP-ribosylated substrate. A novel protein involved in the maintenance of the Golgi structure. J. Biol. Chem. 274, 17705-17710.
36. Stinchcombe, J. C., Nomoto, H., Cutler, D. F., Hopkins, C. R., 1995. Anterograde and retrograde traffic between the rough endoplasmic reticulum and the Golgi complex. J. Cell Biol. 131, 1387-1401.
37. Tanaka, K., Mitsushima, A., Fukudome, H., Kashima, Y., 1986. Three-dimensional architecture of the Golgi complex observed by high resolution scanning electron microscopy. J. Submicrosc. Cytol. 18, 1-9.
38. Tang, B. L., Low, S. H., Hauri, H.-P., Hong, W., 1995. Segregation of ERGIC53 and the mammalian KDEL receptor upon exit from the 15 °C compartment. Eur. J. Cell Biol. 68, 398-410.
39. Velasco, A., Hendricks, L., Moremen, K. W., Tulsiani, D. R., Touster, O., Farquhar, M. G., 1993. Cell type-dependent variations in the subcellular distribution of alpha-mannosidase I. and II. J. Cell Biol. 122, 39-51.
40. Weidman, P. J., 1995. Anterograde transport through the Golgi complex: do Golgi tubules hold the key? Trends Cell Biol. 5, 302-305.
41. Weigert, R., Colanzi, A., Mironov, A. A., Buccione, R., Cericola, C., Sciulli, M. G., Santini, G., Flati, S., Fusella, A., Donaldson, J. G., Di Girolamo, M., Corda, D., De Matteis, M. A., Luini, A., 1997. Characterization of chemical inhibitors of brefeldin A-activated mono-ADP-ribosylation. J. Biol. Chem. 272, 14200-14207.
42. Weigert, R., Silletta, M. G., Spanò, S., Turacchio, G., Cericola, C., Colanzi, A., Senatore, S., Mancini, R., Polishchuk, E. V., Salmona, M., Facchiano, F., Burger, K. N., Mironov, A., Luini, A., Corda, D., 1999. CtBP/BARS induces fission of Golgi membranes by acylating lysophosphatidic acid. Nature 402, 429-433.
43. White, J., Keller, P., Stelzer, E. H., 2001. Spatial partitioning of secretory cargo from Golgi resident proteins in live cells. BMC Cell Biol. 2, 19.