메뉴 건너뛰기




Volumn 83, Issue 1-2, 2004, Pages 103-116

Differential roles of the Leloir pathway enzymes and metabolites in defining galactose sensitivity in yeast

Author keywords

Galactokinase (GALK); Galactose; Galactose 1 phosphate; Galactose 1 phosphate uridylyltransferase (GALT); Leloir pathway; UDP galactose 4 epimerase (GALE); Yeast

Indexed keywords

ALCOHOL; EPIMERASE; GALACTOSE; GLYCEROL; PHOSPHOTRANSFERASE; TRANSFERASE;

EID: 4744347780     PISSN: 10967192     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ymgme.2004.07.005     Document Type: Article
Times cited : (68)

References (58)
  • 1
    • 0029920614 scopus 로고    scopus 로고
    • The Leloir pathway: A mechanistic imperative for three enzymes to change the stereochemical configuration of a single carbon in galactose
    • P.A. Frey The Leloir pathway: a mechanistic imperative for three enzymes to change the stereochemical configuration of a single carbon in galactose The FASEB 10 1996 461 470
    • (1996) The FASEB , vol.10 , pp. 461-470
    • Frey, P.A.1
  • 3
    • 0242498430 scopus 로고    scopus 로고
    • Structure and function of enzymes of the Leloir pathway for galactose metabolism
    • H.M. Holden, I. Rayment, and J.B. Thoden Structure and function of enzymes of the Leloir pathway for galactose metabolism J. Biol. Chem. 278 2003 43885 43888
    • (2003) J. Biol. Chem. , vol.278 , pp. 43885-43888
    • Holden, H.M.1    Rayment, I.2    Thoden, J.B.3
  • 4
    • 0000344073 scopus 로고
    • The enzymatic conversion of glucosamine to galactosamine
    • F. Maley, and G.F. Maley The enzymatic conversion of glucosamine to galactosamine Biochim. Biophys. Acta 31 1959 577 578
    • (1959) Biochim. Biophys. Acta , vol.31 , pp. 577-578
    • Maley, F.1    Maley, G.F.2
  • 5
    • 0021035009 scopus 로고
    • Co-purification and characterization of UDP-glucose 4-epimerase and UDP-N-acetylglucosamine 4-epimerase from porcine submaxillary glands
    • F. Piller, M.H. Hanlon, and R.L. Hill Co-purification and characterization of UDP-glucose 4-epimerase and UDP-N-acetylglucosamine 4-epimerase from porcine submaxillary glands J. Biol. Chem. 258 1983 10774 10778
    • (1983) J. Biol. Chem. , vol.258 , pp. 10774-10778
    • Piller, F.1    Hanlon, M.H.2    Hill, R.L.3
  • 6
    • 0022527678 scopus 로고
    • Reversible defects in O-linked glycosylation and LDL receptor expression in a UDP-Gal/UDP-GalNAc 4-epimerase deficient mutant
    • D. Kingsley, K.F. Kozarsky, L. Hobbie, and M. Krieger Reversible defects in O-linked glycosylation and LDL receptor expression in a UDP-Gal/UDP-GalNAc 4-epimerase deficient mutant Cell 44 1986 749 759
    • (1986) Cell , vol.44 , pp. 749-759
    • Kingsley, D.1    Kozarsky, K.F.2    Hobbie, L.3    Krieger, M.4
  • 7
    • 0034435252 scopus 로고    scopus 로고
    • Galactosaemia and allelic variation at the galactose-1-phosphate uridyltransferase gene: A complex relationship between genotype and phenotype
    • L. Tyfield Galactosaemia and allelic variation at the galactose-1-phosphate uridyltransferase gene: a complex relationship between genotype and phenotype Eur. J. Pediatr. 159 2000 S204 S207
    • (2000) Eur. J. Pediatr. , vol.159
    • Tyfield, L.1
  • 8
    • 0025648036 scopus 로고
    • Long-term prognosis in galactosemia: Results of a survey of 350 cases
    • D.D. Waggoner, N.R.M. Buist, and G.N. Donnell Long-term prognosis in galactosemia: results of a survey of 350 cases J. Inher. Metab. Dis. 13 1990 802 818
    • (1990) J. Inher. Metab. Dis. , vol.13 , pp. 802-818
    • Waggoner, D.D.1    Buist, N.R.M.2    Donnell, G.N.3
  • 9
    • 0019773996 scopus 로고
    • Galactosemia: A new severe variant due to uridine diphosphate galactose-4-epimerase deficiency
    • J.B. Holton, M.G. Gillett, R. MacFaul, and R. Young Galactosemia: a new severe variant due to uridine diphosphate galactose-4-epimerase deficiency Arch. Dis. Child 56 1981 885 887
    • (1981) Arch. Dis. Child , vol.56 , pp. 885-887
    • Holton, J.B.1    Gillett, M.G.2    MacFaul, R.3    Young, R.4
  • 12
    • 0029119644 scopus 로고
    • Galactose-1-phosphate in the pathophysiology of galactosemia
    • R. Gitzelmann Galactose-1-phosphate in the pathophysiology of galactosemia Eur. J. Pediatr. 154 Suppl. 2 1995 S45 S49
    • (1995) Eur. J. Pediatr. , vol.154 , Issue.2
    • Gitzelmann, R.1
  • 13
    • 0042365182 scopus 로고    scopus 로고
    • Insights into the pathogenesis of galactosemia
    • N.D. Leslie Insights into the pathogenesis of galactosemia Annu. Rev. Nutr. 23 2003 59 80
    • (2003) Annu. Rev. Nutr. , vol.23 , pp. 59-80
    • Leslie, N.D.1
  • 14
    • 78651156199 scopus 로고
    • Enzymatic expression and genetic linkage of genes controlling galactose utilization in Saccharomyces
    • H.C. Douglas, and D.C. Hawthorne Enzymatic expression and genetic linkage of genes controlling galactose utilization in Saccharomyces Genetics 49 1964 837 844
    • (1964) Genetics , vol.49 , pp. 837-844
    • Douglas, H.C.1    Hawthorne, D.C.2
  • 15
    • 0032785219 scopus 로고    scopus 로고
    • Expression of human inositol monophosphatase suppresses galactose toxicity in Saccharomyces cerevisiae: Possible implications for galactosemia
    • D.V. Mehta, A. Kabir, and P.J. Bhat Expression of human inositol monophosphatase suppresses galactose toxicity in Saccharomyces cerevisiae: possible implications for galactosemia Biochem. Biophys. Acta 1454 1999 217 226
    • (1999) Biochem. Biophys. Acta , vol.1454 , pp. 217-226
    • Mehta, D.V.1    Kabir, A.2    Bhat, P.J.3
  • 16
    • 0033969234 scopus 로고    scopus 로고
    • Multiple copies of MRG19 suppress transcription of the GAL1 promoter in a GAL80-dependent manner in Saccharomyces cerevisiae
    • M.A. Kabir, F.A. Khanday, D.V. Mehta, and P.J. Bhat Multiple copies of MRG19 suppress transcription of the GAL1 promoter in a GAL80-dependent manner in Saccharomyces cerevisiae Mol. Gen. Genet. 262 2000 1113 1122
    • (2000) Mol. Gen. Genet. , vol.262 , pp. 1113-1122
    • Kabir, M.A.1    Khanday, F.A.2    Mehta, D.V.3    Bhat, P.J.4
  • 17
    • 0034630727 scopus 로고    scopus 로고
    • Overexpression of human UDP-glucose pyrophosphorylase rescues galactose-1-phosphate uridyltransferase-deficient yeast
    • K. Lai, and L. Elsas Overexpression of human UDP-glucose pyrophosphorylase rescues galactose-1-phosphate uridyltransferase-deficient yeast Biochem. Biophys. Res. Commun. 271 2000 392 400
    • (2000) Biochem. Biophys. Res. Commun. , vol.271 , pp. 392-400
    • Lai, K.1    Elsas, L.2
  • 18
    • 0033745216 scopus 로고    scopus 로고
    • Studies of the V94M-substituted human UDP-galactose-4-epimerase enzyme associated with generalized epimerase-deficiency galactosemia
    • T. Wohlers, and J.L. Fridovich-Keil Studies of the V94M-substituted human UDP-galactose-4-epimerase enzyme associated with generalized epimerase-deficiency galactosemia J. Inher. Metab. Dis. 23 2000 713 729
    • (2000) J. Inher. Metab. Dis. , vol.23 , pp. 713-729
    • Wohlers, T.1    Fridovich-Keil, J.L.2
  • 19
    • 0035815717 scopus 로고    scopus 로고
    • Relationship between genotype, activity, and galactose sensitivity in yeast expressing patient alleles of human galactose-1-phosphate uridylyltransferase
    • K. Riehman, C. Crews, and J.L. Fridovich-Keil Relationship between genotype, activity, and galactose sensitivity in yeast expressing patient alleles of human galactose-1-phosphate uridylyltransferase J. Biol. Chem. 276 2001 10634 10640
    • (2001) J. Biol. Chem. , vol.276 , pp. 10634-10640
    • Riehman, K.1    Crews, C.2    Fridovich-Keil, J.L.3
  • 20
    • 0023392267 scopus 로고
    • A method for gene disruption that allows repeated use of URA3 selection in the construction of multiply disrupted yeast strains
    • E. Alani, L. Cao, and N. Kleckner A method for gene disruption that allows repeated use of URA3 selection in the construction of multiply disrupted yeast strains Genetics 116 1987 541 545
    • (1987) Genetics , vol.116 , pp. 541-545
    • Alani, E.1    Cao, L.2    Kleckner, N.3
  • 22
    • 0026715777 scopus 로고
    • A method for the determination of changes of glycolytic metabolites in yeast on a subsecond time scale using extraction at neutral pH
    • W. de Koning, and K. van Dam A method for the determination of changes of glycolytic metabolites in yeast on a subsecond time scale using extraction at neutral pH Anal. Biochem. 204 1992 118 123
    • (1992) Anal. Biochem. , vol.204 , pp. 118-123
    • De Koning, W.1    Van Dam, K.2
  • 23
    • 0032528360 scopus 로고    scopus 로고
    • Cleanup and analysis of sugar phosphates in biological extracts by using solid-phase extraction and anion-exchange chromatography with pulsed amperometric detection
    • H.P. Smits, A. Cohen, T. Buttler, J. Nielsen, and L. Olsson Cleanup and analysis of sugar phosphates in biological extracts by using solid-phase extraction and anion-exchange chromatography with pulsed amperometric detection Anal. Biochem. 261 1998 36 42
    • (1998) Anal. Biochem. , vol.261 , pp. 36-42
    • Smits, H.P.1    Cohen, A.2    Buttler, T.3    Nielsen, J.4    Olsson, L.5
  • 24
    • 0023493883 scopus 로고
    • A model fungal gene regulatory mechanism: The GAL genes of Saccharomyces cerevisiae
    • M. Johnston A model fungal gene regulatory mechanism: the GAL genes of Saccharomyces cerevisiae Microbiol. Rev. 51 1987 458 476
    • (1987) Microbiol. Rev. , vol.51 , pp. 458-476
    • Johnston, M.1
  • 25
    • 0034967623 scopus 로고    scopus 로고
    • Transcriptional control of the GAL/MEL regulon of yeast Saccharomyces cerevisiae: Mechanism of galactose-mediated signal transduction
    • P. Bhat, and T. Murthy Transcriptional control of the GAL/MEL regulon of yeast Saccharomyces cerevisiae: mechanism of galactose-mediated signal transduction Mol. Microbiol. 40 2001 1059 1066
    • (2001) Mol. Microbiol. , vol.40 , pp. 1059-1066
    • Bhat, P.1    Murthy, T.2
  • 26
    • 0031810672 scopus 로고    scopus 로고
    • Yeast carbon catabolite repression
    • J. Gancedo Yeast carbon catabolite repression Microbiol. Mol. Biol. Rev. 62 1998 334 361
    • (1998) Microbiol. Mol. Biol. Rev. , vol.62 , pp. 334-361
    • Gancedo, J.1
  • 27
    • 0026699308 scopus 로고
    • CLB5: A novel B cyclin from budding yeast with a role in S phase
    • C.B. Epstein, and F.R. Cross CLB5: a novel B cyclin from budding yeast with a role in S phase Genes Dev. 6 1992 1695 1706
    • (1992) Genes Dev. , vol.6 , pp. 1695-1706
    • Epstein, C.B.1    Cross, F.R.2
  • 28
    • 0041530874 scopus 로고
    • Evidence for an accessory pathway of galactose metabolism in mammalian liver
    • K.J. Isselbacher Evidence for an accessory pathway of galactose metabolism in mammalian liver Science 126 1957 652 654
    • (1957) Science , vol.126 , pp. 652-654
    • Isselbacher, K.J.1
  • 29
    • 0035716448 scopus 로고    scopus 로고
    • Evidence for alternate galactose oxidation in a patient with deletion of the galactose-1-phosphate uridyltransferase gene
    • G.T. Berry, N. Leslie, R. Reynolds, C.T. Yager, and S. Segal Evidence for alternate galactose oxidation in a patient with deletion of the galactose-1-phosphate uridyltransferase gene Mol. Genet. Metab. 72 2001 316 321
    • (2001) Mol. Genet. Metab. , vol.72 , pp. 316-321
    • Berry, G.T.1    Leslie, N.2    Reynolds, R.3    Yager, C.T.4    Segal, S.5
  • 30
    • 0034834630 scopus 로고    scopus 로고
    • Oxidation of galactose by galactose-1-phosphate uridyltransferase- deficient lymphoblasts
    • C. Yager, J. Gibson, B. States, L.J. Elsas, and S. Segal Oxidation of galactose by galactose-1-phosphate uridyltransferase-deficient lymphoblasts J. Inherit. Metab. Dis. 24 2001 465 476
    • (2001) J. Inherit. Metab. Dis. , vol.24 , pp. 465-476
    • Yager, C.1    Gibson, J.2    States, B.3    Elsas, L.J.4    Segal, S.5
  • 32
    • 0030826263 scopus 로고    scopus 로고
    • Characterization of two mutations associated with epimerase-deficiency galactosemia using a yeast expression system for human UDP-galactose-4-epimerase
    • B.B. Quimby, A. Alano, S. Almashanu, A.M. DeSandro, T.M. Cowan, and J.L. Fridovich-Keil Characterization of two mutations associated with epimerase-deficiency galactosemia using a yeast expression system for human UDP-galactose-4-epimerase Am. J. Hum. Gen. 61 1997 590 598
    • (1997) Am. J. Hum. Gen. , vol.61 , pp. 590-598
    • Quimby, B.B.1    Alano, A.2    Almashanu, S.3    Desandro, A.M.4    Cowan, T.M.5    Fridovich-Keil, J.L.6
  • 33
    • 0034040017 scopus 로고    scopus 로고
    • UDPgalactose epimerase in lens and fibroblasts: Activity expression in patients with cataracts and mental retardation
    • Y.S. Shin, G.C. Korenke, P. Huddke, I. Knerr, and T. Podskarbi UDPgalactose epimerase in lens and fibroblasts: activity expression in patients with cataracts and mental retardation J. Inherit. Metab. Dis. 23 2000 383 386
    • (2000) J. Inherit. Metab. Dis. , vol.23 , pp. 383-386
    • Shin, Y.S.1    Korenke, G.C.2    Huddke, P.3    Knerr, I.4    Podskarbi, T.5
  • 34
    • 0033073396 scopus 로고    scopus 로고
    • Identification and characterization of a mutation, in the human UDP Galactose-4-epimerase gene, associated with generalized epimerase-deficiency galactosemia
    • T.M. Wohlers, N.C. Christacos, M.T. Harreman, and J.L. Fridovich-Keil Identification and characterization of a mutation, in the human UDP Galactose-4-epimerase gene, associated with generalized epimerase-deficiency galactosemia Am. J. Hum. Gen. 64 1999 462 470
    • (1999) Am. J. Hum. Gen. , vol.64 , pp. 462-470
    • Wohlers, T.M.1    Christacos, N.C.2    Harreman, M.T.3    Fridovich-Keil, J.L.4
  • 36
    • 0035715102 scopus 로고    scopus 로고
    • Galactose metabolism in mice with galactose-1-phosphate uridyltransferase deficiency: Sucklings and 7-week-old animals fed a high-galactose diet
    • C. Ning, R. Reynolds, J. Chen, C. Yager, G.T. Berry, N. Leslie, and S. Segal Galactose metabolism in mice with galactose-1-phosphate uridyltransferase deficiency: sucklings and 7-week-old animals fed a high-galactose diet Mol. Genet. Metab. 72 2001 306 315
    • (2001) Mol. Genet. Metab. , vol.72 , pp. 306-315
    • Ning, C.1    Reynolds, R.2    Chen, J.3    Yager, C.4    Berry, G.T.5    Leslie, N.6    Segal, S.7
  • 37
    • 0028879596 scopus 로고
    • Endogenous synthesis of galactose in normal men and patients with hereditary galactosemia
    • G.T. Berry, I. Nissim, Z. Lin, A.T. Mazur, J.B. Gibson, and S. Segal Endogenous synthesis of galactose in normal men and patients with hereditary galactosemia Lancet 346 1995 1073 1074
    • (1995) Lancet , vol.346 , pp. 1073-1074
    • Berry, G.T.1    Nissim, I.2    Lin, Z.3    Mazur, A.T.4    Gibson, J.B.5    Segal, S.6
  • 39
    • 0015972305 scopus 로고
    • Galactose metabolism in a patient with hereditary galactokinase deficiency
    • R. Gitzelmann, H.J. Wells, and S. Segal Galactose metabolism in a patient with hereditary galactokinase deficiency Eur. J. Clin. Invest. 4 1974 79 84
    • (1974) Eur. J. Clin. Invest. , vol.4 , pp. 79-84
    • Gitzelmann, R.1    Wells, H.J.2    Segal, S.3
  • 40
    • 0015794540 scopus 로고
    • Uridine diphosphate galastose 4-epimerase in human and other mammalian hemolysates
    • W.R. Bergren, W.G. Ng, and G.N. Donnell Uridine diphosphate galastose 4-epimerase in human and other mammalian hemolysates Biochim. Biophys. Acta 315 1973 464 472
    • (1973) Biochim. Biophys. Acta , vol.315 , pp. 464-472
    • Bergren, W.R.1    Ng, W.G.2    Donnell, G.N.3
  • 41
    • 0015504322 scopus 로고
    • A study of galactokinase and glucose 4-epimerase from normal and galactosemic skin fibroblasts
    • C.M. Chacko, L. McCrone, and H.L. Nadler A study of galactokinase and glucose 4-epimerase from normal and galactosemic skin fibroblasts Biochim. Biophys. Acta 284 1972 552 555
    • (1972) Biochim. Biophys. Acta , vol.284 , pp. 552-555
    • Chacko, C.M.1    McCrone, L.2    Nadler, H.L.3
  • 42
    • 0027421406 scopus 로고
    • Developmental and tissue-specific modulation of rat galactose-1-phosphate uridyltransferase steady state messenger RNA and specific activity levels
    • R. Heidenreich, J. Mallee, S. Rogers, and S. Segal Developmental and tissue-specific modulation of rat galactose-1-phosphate uridyltransferase steady state messenger RNA and specific activity levels Pediatr. Res. 34 1993 416 419
    • (1993) Pediatr. Res. , vol.34 , pp. 416-419
    • Heidenreich, R.1    Mallee, J.2    Rogers, S.3    Segal, S.4
  • 44
    • 0024994978 scopus 로고
    • Selection and analysis of galactose metabolic pathway variants of a mouse liver cell line
    • K. Zaret, and K. Stevens Selection and analysis of galactose metabolic pathway variants of a mouse liver cell line Mol. Cell Biol. 10 1990 4582 4589
    • (1990) Mol. Cell Biol. , vol.10 , pp. 4582-4589
    • Zaret, K.1    Stevens, K.2
  • 45
  • 46
    • 0025605875 scopus 로고
    • Culture of galactosaemic fibroblasts in the presence of galactose: Effect of inosine
    • M. Pourci, M. Mangeot, T. Soni, and A. Lemonnier Culture of galactosaemic fibroblasts in the presence of galactose: effect of inosine J. Inherit. Metab. Dis. 13 1990 819 828
    • (1990) J. Inherit. Metab. Dis. , vol.13 , pp. 819-828
    • Pourci, M.1    Mangeot, M.2    Soni, T.3    Lemonnier, A.4
  • 47
    • 0030273135 scopus 로고    scopus 로고
    • A mouse model of galactose-1-phosphate uridyl transferase deficiency
    • N.D. Leslie, K.L. Yager, P.D. McNamara, and S. Segal A mouse model of galactose-1-phosphate uridyl transferase deficiency Biochem. Mol. Med. 59 1996 7 12
    • (1996) Biochem. Mol. Med. , vol.59 , pp. 7-12
    • Leslie, N.D.1    Yager, K.L.2    McNamara, P.D.3    Segal, S.4
  • 49
    • 0029116445 scopus 로고
    • The role of polyols in the pathophysiology of hypergalactosemia
    • G.T. Berry The role of polyols in the pathophysiology of hypergalactosemia Eur. J. Pediatr. 154 Suppl. 2 1995 S53 S64
    • (1995) Eur. J. Pediatr. , vol.154 , Issue.2
    • Berry, G.T.1
  • 50
    • 0037220097 scopus 로고    scopus 로고
    • Galactose-1-phosphate is a regulator of inositol monophosphatase: A fact or a fiction?
    • P.J. Bhat Galactose-1-phosphate is a regulator of inositol monophosphatase: a fact or a fiction? Med. Hypotheses 60 2003 123 128
    • (2003) Med. Hypotheses , vol.60 , pp. 123-128
    • Bhat, P.J.1
  • 51
    • 0026346397 scopus 로고
    • Characterization of a novel biochemical abnormality in galactosemia: Deficiency of glycolipids containing galactose or N-acetylgalactosamine and accumulation of precursors in brain and lymphocytes
    • K. Petry, H.T. Greinix, E. Nudelman, H. Eisen, S. Hakomori, H.L. Levy, and J.K.V. Reichardt Characterization of a novel biochemical abnormality in galactosemia: deficiency of glycolipids containing galactose or N-acetylgalactosamine and accumulation of precursors in brain and lymphocytes Biochem. Med. Metab. Biol. 46 1991 93 104
    • (1991) Biochem. Med. Metab. Biol. , vol.46 , pp. 93-104
    • Petry, K.1    Greinix, H.T.2    Nudelman, E.3    Eisen, H.4    Hakomori, S.5    Levy, H.L.6    Reichardt, J.K.V.7
  • 52
    • 0026577583 scopus 로고
    • Abnormal galactosylation of complex carbohydrates in cultured fibroblasts fom patients with galactose-1-phosphate uridyltransferase deficiency
    • K.S. Ornstein, E.J. McGuire, G.T. Berry, S. Roth, and S. Segal Abnormal galactosylation of complex carbohydrates in cultured fibroblasts fom patients with galactose-1-phosphate uridyltransferase deficiency Pediatr. Res. 31 1992 508 511
    • (1992) Pediatr. Res. , vol.31 , pp. 508-511
    • Ornstein, K.S.1    McGuire, E.J.2    Berry, G.T.3    Roth, S.4    Segal, S.5
  • 55
    • 0027759532 scopus 로고
    • The investigation of UDPGlucose and UDPGalactose concentration in red blood cells of patients with classical galactosaemia
    • N.J. Keevill, J. Holton, and J.T. Allen The investigation of UDPGlucose and UDPGalactose concentration in red blood cells of patients with classical galactosaemia Clin. Chim. Acta 221 1993 135 142
    • (1993) Clin. Chim. Acta , vol.221 , pp. 135-142
    • Keevill, N.J.1    Holton, J.2    Allen, J.T.3
  • 56
    • 0028345526 scopus 로고
    • UDP-glucose and UDP-galactose concentrations in cultured skin fibroblasts of patients with classic galactosemia
    • N.J. Keevill, J.B. Holton, and J.T. Allen UDP-glucose and UDP-galactose concentrations in cultured skin fibroblasts of patients with classic galactosemia J. Inher. Metab. Dis. 17 1994 23 26
    • (1994) J. Inher. Metab. Dis. , vol.17 , pp. 23-26
    • Keevill, N.J.1    Holton, J.B.2    Allen, J.T.3
  • 57
    • 0029090524 scopus 로고
    • HPLC analysis of uridine diphosphate sugars: Decreased concentrations of uridine diphosphate galactose in erythrocytes and cultured skin fibroblasts from classical galactosemia patients
    • Y.-K. Xu, F.R. Kaufman, G.N. Donnell, T. Giudici, O. Alfi, and W.G. Ng HPLC analysis of uridine diphosphate sugars: decreased concentrations of uridine diphosphate galactose in erythrocytes and cultured skin fibroblasts from classical galactosemia patients Clin. Chim. Acta 240 1995 21 33
    • (1995) Clin. Chim. Acta , vol.240 , pp. 21-33
    • Xu, Y.-K.1    Kaufman, F.R.2    Donnell, G.N.3    Giudici, T.4    Alfi, O.5    Ng, W.G.6
  • 58
    • 0029081710 scopus 로고
    • Nucleotide sugars: Determination of cellular levels and discrepancies in results
    • Y.S. Shin Nucleotide sugars: determination of cellular levels and discrepancies in results Eur. J. Pediatr. 154 Suppl. 2 1995 S75 S76
    • (1995) Eur. J. Pediatr. , vol.154 , Issue.2
    • Shin, Y.S.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.