Histologic evaluation of nasal epithelium of the middle turbinate in untreated OSAS patients and during nCPAP therapy

Rhinology

Volumn 42, Issue 3, 2004, Pages 153-157

  Schrödter, Sophia ^a,b   Biermann, Eckhardt ^b   Halata, Zdenek ^a  

^a ST GEORGE HOSPITAL   (Germany)

^b UNIVERSITY OF HAMBURG   (Germany)

Author keywords

Histology; Middle turbinate; Nasal mucosa; nCPAP therapy; Sleep apnoea

Indexed keywords

ADULT; AGED; ARTICLE; CELL INFILTRATION; CILIATED EPITHELIUM; CLINICAL ARTICLE; CONNECTIVE TISSUE; CONTROLLED STUDY; EVALUATION; FACIAL BONE; HISTOLOGY; HUMAN; HUMAN TISSUE; LONG TERM CARE; MALE; NASAL BIOPSY; NOSE DISEASE; NOSE MUCOSA; POSITIVE END EXPIRATORY PRESSURE; RESPIRATORY EPITHELIUM; SLEEP APNEA SYNDROME; SQUAMOUS CELL METAPLASIA; SYMPTOMATOLOGY; TISSUE SECTION;

AGED; BASEMENT MEMBRANE; CONTINUOUS POSITIVE AIRWAY PRESSURE; CROSS-SECTIONAL STUDIES; HUMANS; MALE; MIDDLE AGED; NASAL MUCOSA; SLEEP APNEA, OBSTRUCTIVE; TURBINATES;

EID: 4744340552     PISSN: 03000729     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (27)

1. Brander PE, Soirinsuo M, Lohela P (1999) Nasopharyngeal symptoms in patients with obstructive sleep apnea syndrome. Effect of nasal CPAP treatment. Respiration 66: 128-135.
2. Constantinidis J, Knöbber D, Steinhart H, Kuhn J, Iro H (2000a) Fine-structural investigations of the effect of nCPAP-mask application on the nasal mucosa. Acta Otolaryngol 120: 432-437.
3. Constantinidis J, Knöbber D, Steinhart H, Kuhn J, Iro H (2000b) Morphologische und funktionelle Veränderungen der Nasenschleimhaut nach nCPAP-Therapie. HNO 48: 747-752.
4. D'Ambrosio C, Bowman T, Mohsenin V (1999) Quality of life in patients with obstructive sleep apnea: effect of nasal continuous positive airway pressure - a prospective study. Chest 115: 123-129.
5. Durán J, Esnaola S, Rubio R, Iztueta A (2001) Obstructive sleep apnea-hypopnea and related clinical features in a population-based sample of subjects aged 30 to 70 yr. Am J Respir Crit Care Med 163: 685-689.
6. Eccles R (1995) Nasal airways. In: WW Busse, ST Holgate (Eds.) Asthma and Rhinitis. Blackwell Scientific Publications, Boston, USA, pp. 73-79.
7. Engleman HM, Martin SE, Kingshott RN, Mackay TW, Deary IJ, Douglas NJ (1998) Randomised placebo controlled trial of daytime function after continuous positive airway pressure (CPAP) therapy for the sleep apnoea/hypopnoea syndrome. Thorax 53: 341-345.
8. Hayes MJ, McGregor FB, Roberts DN, Schroter RC, Pride NB (1995) Continuous nasal positive airway pressure with a mouth leak: effect on nasal mucosal blood flux and nasal geometry. Thorax 50: 1179-1182.
9. Hui DSC, Choy DKL, Li TST, Ko FWS, Wong KK, Chan JKW, Lai CKW (2001) Determinants of continuous positive airway pressure compliance in a group of Chinese patients with obstructive sleep apnea. Chest 120: 170-176.
10. Kalan A, Kenyon GS, Seemungal TA, Wedzicha JA (1999) Adverse effects of nasal continuous positive airway pressure therapy in sleep apnoea syndrome. J Laryngol Otol 113: 888-892.
11. Keck T, Leiacker R, Heinrich A, Kühnemann S, Rettinger G (2000) Humidity and temperature profile in the nasal cavity. Rhinology 38: 167-171.
12. Kelly JT, Prasad AK, Wexler AS (2000) Detailed flow patterns in the nasal cavity. J Appl Physiol 89: 323-337.
13. Kesten S, Rebuck AS (1990) Ventilatory effects of nasal continuous positive airway pressure. Eur Respir J 3: 498-501.
14. Lojander J, Brander PE, Ämmälä K (1999) Nasopharyngeal symptoms and nasal continuous positive airway pressure therapy in obstructive sleep apnoea syndrome. Acta Otolaryngol 119: 497-502.
15. Lucas AM, Douglas LC (1934) Principles underlying ciliary activity in the respiratory tract. II. A comparison of nasal clearance in man, monkey and other mammals. Arch Otolaryngol 20: 518-541.
16. Luft JH (1961) Improvements in epoxy resin embedding methods. J Biophys Biochem Cytol 9: 409-414.
17. Martins De Araújo MT, Vieira SB, Vasquez EC, Fleury B (2000) Heated humidification or face mask to prevent upper airway dryness during continuous positive airway pressure therapy. Chest 117: 142-147.
18. Massie CA, Hart RW, Peralez K, Richards GN (1999) Effects of humidification on nasal symptoms and compliance in sleep apnea patients using continuous positive airway pressure. Chest 116: 403-408.
19. McArdle N, Devereux G, Heidarnejad H, Engleman HM, Mackay TW, Douglas NJ (1999) Long-term use of CPAP therapy for sleep apnea/hypopnea syndrome. Am J Respir Crit Care Med 159: 1108-1114.
20. Naclerio RM, Proud D, Kagey SA, Lichtenstein LM, Thompson M, Togias A (1995) Cold dry air-induced rhinitis: effect of inhalation and exhalation through the nose. J Appl Physiol 79: 467-471.
21. Pépin JL, Leger EB, Veale D, Langevin B, Robert D, Lévy P (1995) Side effects of nasal continuous positive airway pressure in sleep apnoea syndrome. Chest 107: 375-381.
22. Schrödter S, Biermann E, Halata Z (2003) Histological evaluation of age-related changes in human respiratory mucosa of the middle turbinate. Anat Embryol 207: 19-27.
23. Sullivan CE, Issa FG, Berthon-Jones M, Eves L (1981) Reversal of obstructive sleep apnoea by continuous positive airway pressure applied through the nares. Lancet 1: 862-865.
24. Taylor M (1974) The origin and functions of nasal mucus. Laryngoscope 84: 612-636.
25. Verse T, Lehnhardt E, Pirsig W, Junge-Hülsing B, Kroker B (1999) Welche Nebenwirkungen hat die nächtliche kontinuierliche Überdruckbeatmung (nCPAP) bei Schlafapnoikern im Kopf-Hals-Bereich? Laryngorhinootologie 78: 491-496.
26. Wiest GH, Foerst J, Fuchs FS, Lampert S, Pour Schahin S, Fuchs TOJ, Hahn EG, Ficker JH (2001) Ein Befeuchtersystem für die CPAP-Therapie bei obstruktiver Schlafapnoe - Evaluierung der Leistungsfähigkeit bei wechselnden klimatischen Umgebungsbedingungen. Dtsch Med Wochenschr 126: 294-298.
27. Young T, Palta M, Dempsey J, Skatrud J, Weber S, Badr S (1993) The occurrence of sleep-disordered breathing among middle-aged adults. N Engl J Med 328: 1230-1235.