Pharmacokinetics of a single bolus intravenous, intramuscular and subcutaneous dose of disodium fosfomycin in horses

Journal of Veterinary Pharmacology and Therapeutics

Volumn 31, Issue 4, 2008, Pages 321-327

  Zozaya, D H ^a   Gutierrez O L ^a   Ocampo, C L ^a   Sumano, L H ^a  

^a UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

Author keywords

[No Author keywords available]

Indexed keywords

FOSFOMYCIN;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; BIOAVAILABILITY; BOLUS INJECTION; DOSE TIME EFFECT RELATION; DRUG ADMINISTRATION ROUTE; DRUG BLOOD LEVEL; FEMALE; HORSE; MALE; NONHUMAN; PRIORITY JOURNAL; SINGLE DRUG DOSE;

ANIMALS; ANTI-BACTERIAL AGENTS; AREA UNDER CURVE; BIOLOGICAL AVAILABILITY; FEMALE; FOSFOMYCIN; HALF-LIFE; HORSES; INJECTIONS, INTRAMUSCULAR; INJECTIONS, INTRAVENOUS; INJECTIONS, SUBCUTANEOUS; MALE; METABOLIC CLEARANCE RATE; PROTEIN BINDING;

EQUIDAE;

EID: 47349118542     PISSN: 01407783     EISSN: 13652885     Source Type: Journal    
DOI: 10.1111/j.1365-2885.2008.00970.x     Document Type: Article

References (64)

1. Ailani, R.K., Agastya, G., Ailani, R.K., Mukunda, B.N. Shekar, R. (1999) Doxycycline is a cost-effective therapy for hospitalized patients with community-acquired pneumonia. Archives of Internal Medicine, 159, 266 270.
2. Aramayona, J.J., Bregante, M., Solans, C., Rueda, S., Fraile, L.J. García, M.A. (1997) Pharmacokinetics of fosfomycin in chickens after a single intravenous dose and tissue levels following chronic oral administration. Veterinary Research, 28, 581 588.
3. Barry, A.L. Brown, S.D. (1995) Antibacterial spectrum of fosfomycin trometamol. Journal of Antimicrobial Chemotherapy, 35, 228 230.
4. Baverud, V., Gustafsson, A., Franklin, A., Lindholm, A. Gunnarsson, A. (1997) Clostridium difficile associated with acute colitis in mature horses treated with antibiotics. Equine Veterinary Journal, 29, 279 284.
5. Bayrak, O. (2006) Is a single-dose fosfomycin trometamol a good alternative for asymptomatic bacteriuria in the second trimester of pregnancy? International Urogynecology Journal and Pelvic Floor Dysfunction, 29, 521 524.
6. Bennett, J.V., Brodie, J., Benner, E. Kirby, W. (1966) Simplified, accurate method for antibiotic assay of clinical specimens. Applied Microbiology, 14, 170 177.
7. Bergogne-Berezin, E., Kafe, H., Daumal, M., Gillon, J.C. Bergan, T. (1983) Penetration of fosfomycin into bronchial secretions. Pathologie Biologie, 31, 519 521.
8. Berthelot, G., Bergogne-Berezin, E., Kafe, H., Daumal, M. Gillon, J.C. (1983) Etude de la pénétration de la fosfomycine dans les sécrétions bronchiques. Pathologie-Biologie, 31, 519 521.
9. Borsa, F., Leroy, A., Fillastre, J.P., Godin, M. Moulin, B. (1988) Comparative pharmacokinetics of tromethamine fosfomycin and calcium fosfomycin in young and elderly adults. Antimicrobial Agents Chemotherapy, 32, 938 941.
10. Brunner, M., Reinprecht, A., Illievich, U., Spiss, C.K., Dietrich, K., Houte van, M. Müller, M. (2002) Penetration of fosfomycin into the parenchyma of human brain: a case study in three patients. British Journal of Clinical Pharmacology, 54, 548 551.
11. Burgess, D.S., Frei, C.R., Lewis II., J.S., Fiebelkorn, K.R. Jorgensen, J.H. (2007) The contribution of pharmacokinetico-pharmacodynamic modeling with Monte Carlo simulation to the development of susceptibility breakpoints for Neisseria meningitidis. Clinical Microbiology and Infection, 13, 33 39.
12. Cho, N., Sekiya, M., Chin, I., Fukunaga, K. Kunii, K. (1985) Fundamental and clinical studies on fosfomycin sodium in the field of obstetrics and gynecology. Japanese Journal of Antibiotics, 38, 2045 2056.
13. Claes, J., Van de Heyning, P.H., Creten, W. Van Hoof, M. (1992) Side effects of repeated ototopical application of fosfomycin. An animal study. Archives of Otolaryngology, 118, 951 955.
14. Cree, M., Stacey, S., Graham, N. Wainwright, C. (2006) Fosfomycin - investigation of a possible new route of administration of an old drug. A case study. Journal of Cystic Fibrosis, 6, 244 246.
15. Deguchi, K. (1995) Antibacterial activities of fosfomycin against recent clinical isolates from patients of otitis media and otitis externa. Japanese Journal of Antibiotics, 48, 293 298.
16. Fernandez Lastra, C., Marino, E.L. Dominguez-Gil, A. (1987) Phosphomycin levels in serum and interstitial tissue fluid in a multiple dosage regimen in rabbits. Arzneimittel-Forschung, 37, 927 929.
17. Fernández Lastra, C., Marino, E.L. Dominguez-Gil, A. (1986) Linearity of the pharmacokinetics of phosphomycin in serum and interstitial tissue fluid in rabbits. Arzneimittel-Forschung, 36, 1518 1520.
18. Fernandez, A., EffiPayuelo, R., Gómez, J., Ramos, J., Loste, A. Marca, M. (1998) Efficacy of phosphomycin in the control of Escherichia coli infection of broiler chickens. Research in Veterinary Science, 65, 201 204.
19. Fernandez, A., Lara, C., Loste, A., Calvo, S. Marca, M. (2001) Control of Salmonella enteritidis phage type 4 experimental infection by fosfomycin in newly hatched chicks. Comparative Immunology, Microbiology and Infectious Diseases, 24, 207 216.
20. Fernández, A., Lara, C., Loste, A. Marca, M. (2002) Efficacy of calcium fosfomycin for the treatment of experimental infections of broiler chickens with Escherichia coli O78:K80. Veterinary Research Communications, 26, 427 436.
21. Gattringer, R., Meyer, B., Heinz, G. Guttmann, C. (2006) Single-dose pharmacokinetics of fosfomycin during continuous venovenous haemofiltration. Journal of Antimicrobial Chemotherapy, 58, 367 371.
22. Gialdroni, G. (1990) Fosfomycin trometamol: historical background and clinical development. Infection, 18, 57 59.
23. Gobernado, M. (2003) Fosfomicina. Revista Española de Quimioterapia, 16, 15 40.
24. Goto, M., Nakajima, S. Yamashina, H. (1981) Fosfomycin kinetics after intravenous and oral administration to human volunteers. Antimicrobial Agents and Chemotherapy, 20, 393 397.
25. Gray, J.K., Gascoyne-Binzi, M.D., Nicholson, P., Heritage, J. Hawkey, P.M. (2001) Transmissible fosfomycin resistance markers in urinary isolates and imported foodstuffs in the UK during 1994 and 1995. Journal of Antimicrobial Chemotherapy, 48, 744 745.
26. Gustafsson, A.B.V., Gunnarsson, A., Rantzien, M.H., Lindholm, A. Franklin., A. (1997) The association of erythromycin ethylsuccinate with acute colitis in horses in Sweden. Equine Veterinary Journal, 29, 314 318.
27. Gutiérrez, O.L., Ocampo, C.L., Aguilera, J.R., Luna, J. Sumano, L.H. (2007) Pharmacokinetics of disodium-fosfomycin in mongrel dogs. Research in Veterinary Science, [Epub ahead of print].
28. Hamilton Miller, J.M. (1992) In vitro activity of fosfomycin against 'problem' gram-positive cocci. Microbios, 71, 95 103.
29. Hernandez, E. (2001) Determination of fosfomycin in chicken plasma samples by gas chromatography: application to pharmacokinetic studies. Chromatographia, 54, 365 368.
30. Joukhadar, C., Klein, N., Dittrich, P., Zeitlinger, M., Gkekppert, A. Skhirtladze, K. (2003) Target site penetration of fosfomycin in critically ill patients. Journal of Antimicrobial Chemotherapy, 51, 1247 1252.
31. Kirby, W. (1977) Pharmacokinetics of fosfomycin. Chemotherapy, 23 (Suppl. 1 141 151.
32. Kofler, J.W. (1986) Studies of the penetrating ability of fosfomycin into the aqueous humor and vitreous body of the eye. Klinische Monatsblatter fur Augenheilkunde, 18, 240 242.
33. Krause, R., Patruta, S., Daxböck, F., Fladerer, P. Wenisch, C. (2001) The effect of fosfomycin on neutrophil function. Journal of Antimicrobial Chemotherapy, 47, 141 146.
34. Kuemmerle, H., Murakawa, T. De Santis, F. (1987) Pharmacokinetic evaluation of fosmidomycin, a new phosphonic acid antibiotic. Chemioterapia, 6, 113 119.
35. Legat, F.J. (2003) Penetration of fosfomycin into inflammatory lesions in patients with cellulitis or diabetic foot syndrome. Antimicrobial Agents and Chemotherapy, 47, 371 374.
36. Marques, F.A. (2003) Terapéutica Experimental de Osteomielitis por Pseudomonas aeruginosa: estudio de fosfomicina. Tesis doctoral, Universidad Complutense de Madrid.
37. Mazzei, T.C., Fallania, S., Arriguccia, S. Novellia, A. (2006) Pharmacokinetic and pharmacodynamic aspects of antimicrobial agents for the treatment of uncomplicated urinary tract infections. International Journal of Antimicrobial Agents, 28 (Suppl. 1 35 41.
38. McKellar, Q.A., Sanchez Bruni, S.F. Jones, D.G. (2004) Pharmacokinetic/pharmacodinamic relationships of antimicrobial drugs used in veterinary medicine. Journal of Veterinary Pharmacology and Therapeutics, 27, 503 514.
39. Michel, C.V., Delisle, F., Lependoven, C. Mignon, F. (1989) Treatment of peritonitis in continuous ambulatory peritoneal dialysis with a combination of fosfomycin and pefloxacin. Pathologie Biologie, 37, 269 271.
40. Mirakhur, A. (2003) Fosfomycin therapy for multiresistant Pseudomonas aeruginosa in cystic fibrosis. Journal of Cystic Fibrosis, 2, 19 24.
41. Morikaw, K., Nonaka, M., Torii, I. Morikawa, S. (2003) Modulatory effect of fosfomycin on acute inflammation in the rat air pouch model. International Journal of Antimicrobial Agents, 21, 334 340.
42. Nakamura, T., Hashimoto, I., Sawada, Y., Mikami, J. Bekki, E. (1985) Clinical studies on fosfomycin sodium following intravenous administration. The Japanese Journal of Antibiotics, 38, 57 67.
43. Nakazawa, H. (2003) Enhancement of antimicrobial effects of various antibiotics against methicillin-resistant Staphylococcus aureus (MRSA) by combination with fosfomycin. Journal of Infection and Chemotherapy, 9, 304 309.
44. Nau, R. (1995) Activity of fosfomycin in a rabbit model of experimental pneumococcal meningitis. Journal of Antimicrobial Chemotherapy, 36, 997 1004.
45. Patel, S.S., Balfour, J.A. Bryson, H.M. (1997) Fosfomycin tromethamine. A review of its antibacterial activity, pharmacokinetic properties and therapeutic efficacy as a single-dose oral treatment for acute uncomplicated lower urinary tract infections. Drugs, 53, 637 656.
46. Peek, S.F., Semrad, S.D. Perkins, G.A. (2002) Clostridial myonecrosis in horses. Equine Veterinary Journal, 14, 163 168.
47. Pérez Fernández, P., Herrera, I., Martinez, P., Gomez Lus, M.L. Prieto, J. (1995) Enhancement of the susceptibility of Staphylococcus aureus to phagocytosis after treatment with fosfomycin compared with other antimicrobial agents. Chemotherapy, 41, 45 49.
48. Pfausler, B. (2004) Concentrations of fosfomycin in the cerebrospinal fluid of neurointensive care patients with ventriculostomy-associated ventriculitis. Journal of Antimicrobial Chemotherapy, 53, 848 852.
49. Pruekprasert, K.S. (2005) In vitro activity of fosfomycin-gentamicin, fosfomycin-ceftazidime, fosfomycin-imipenem and ceftazidime-gentamicin combinations against ceftazidime-resistant Pseudomonas aeruginosa. Southeast Asian Journal of Tropical Medicine and Public Health, 36, 1239 1242.
50. Ribes, S. (2006) Evaluation of fosfomycin alone and in combination with ceftriaxone or vancomycin in an experimental model of meningitis caused by two strains of cephalosporin-resistant Streptococcus pneumoniae. Journal of Antimicrobial Chemotherapy, 57, 931 936.
51. Rogers, T.O. Birnbaum, J. (1974) Biosynthesis of fosfomycin by Streptomyces fradiae. Antimicrobial Agents and Chemotheraphy, 5, 121 132.
52. Rudenko, N. Dorofeyev, A. (2005) Prevention of recurrent lower urinary tract infections by long-term administration of fosfomycin trometamol. Double blind, randomized, parallel group, placebo controlled study. Arzneimittelforschung, 55, 420 427.
53. Sauermann, R. (2005) Antibiotic abscess penetration: fosfomycin levels measured in pus and simulated concentration-time profiles. Antimicrobial Agents and Chemotherapy, 49, 4448 4454.
54. Schito, G. (2003) Why fosfomycin trometamol as first line therapy for uncomplicated UTI International Journal of Antimicrobial Agents, 22, 79 83.
55. Segre, G., Bianchi, E., Cataldi, A. Zannini, G. (1987) Pharmacokinetic profile of fosfomycin trometamol (Monuril). European Urology, 13 (Suppl. 1 56 63.
56. Singhvi, S.M., Heald, A.F., Gadekbusch, H.H., Resnick, M.E., Ditazio, L.T. Leitz, M.A. (1977) Human serum protein binding of cephalosporin antibiotics in vitro. Journal of Laboratory and Clinical Medicine, 89, 414 420.
57. Stengel, D. (2005) Second-line treatment of limb-threatening diabetic foot infections with intravenous fosfomycin. Journal of Chemotherapy, 17, 527 535.
58. Stricker, T., Fröhlich, S. Nadal, D. (1998) Osteomyelitis and septic arthritis due to Citrobacter freundii and Haemophilus influenzae type b. Journal of Paediatrics and Child Health, 34, 90.
59. Strickley, R.G. (2004) Solubilizing excipients in oral and injectable formulations. Pharmaceutical Research, 21, 201 230.
60. Sumano, L.H., Ocampo, C.L. Gutiérrez, O.L. (2007) Intravenous and intramuscular pharmacokinetics of a single-daily dose of disodium fosfomycin in cattle, administered for three days. Journal of Veterinary Pharmacology and Therapeutics, 30, 49 54.
61. Tessier, F. Quentin, C. (1997) In vitro activity of fosfomycin combined with ceftazidime, imipenem, amikacin, and ciprofloxacin against Pseudomonas aeruginosa. European Journal of Clinical Microbiology Infectious Diseases, 16, 159 162.
62. Vecchio, S., Rodante, F. Tomassetti, M. (2001) Thermal stability of disodium and calcium phosphomycin and the effects of the excipients evaluated by thermal analysis. Journal of Pharmaceutical and Biomedical Analysis, 24, 1111 1123.
63. Williams, J.J. (2001) Sensibilidad in vitro de cepas de Actinobacillus pleuropneumoniae y Pasteurella multocida tipo "a" ante diferentes antimicrobianos. Revista Biomed, 12, 172 179.
64. Zeitlinger, M.A., Sauermann, R., Traunmüller, F., Georgopoulos, A., Müller, M. Joukhadar, C. (2004) Impact of plasma protein binding on antimicrobial activity using time-killing curves. Journal of Antimicrobial Chemotherapy, 54, 876 880.