Synthesis and biological activity of some new flavonyl-2,4-thiazolidinediones

Bioorganic and Medicinal Chemistry

Volumn 16, Issue 14, 2008, Pages 6747-6751

  Bozdaǧ Dündar, Oya ^a   Verspohl, Eugen J ^b   Daş Evcimen, Net ^a   Kaup, Rebecca M ^b   Bauer, Katrin ^b   Sarikaya, Mutlu ^a   Evranos, Begüm ^a   Ertan, Rahmiye ^a  

^a ANKARA UNIVERSITY   (Turkey)

^b UNIVERSITY OF MÜNSTER   (Germany)

Author keywords

2,4 Thiazolidinediones; Aldose reductase inhibition; Antidiabetic agents; Flavone; Flavonyl 2,4 thiazolidinediones; Insulinotropic activity; Synthesis

Indexed keywords

2,4 THIAZOLIDINEDIONE DERIVATIVE; [2,4 DIOXO 5 [(4 OXO 2 PHENYL 4H CHROMEN 6 YL)METHYLENE] 1,3 THIAZOLIDINE 3YL]ACETIC ACID; [2,4 DIOXO 5 [3 (4 OXO 4H CHROMEN 2 YL)BENZYLIDENE] 1,3 THIAZOLIDINE 3YL]ACETIC ACID; [2,4 DIOXO 5 [4 (4 OXO 4H CHROMEN 2 YL)BENZYLIDENE] 1,3 THIAZOLIDINE 3YL]ACETIC ACID; ALDEHYDE REDUCTASE; ETHYL[2,4 DIOXO 5 [(4 OXO 2 PHENYL 4H CHROMEN 6 YL)METHYLENE] 1,3 THIAZOLIDINE 3YL]ACETATE; ETHYL[2,4 DIOXO 5 [3 (4 OXO 4H CHROMEN 2 YL)BENZYLIDENE] 1,3 THIAZOLIDINE 3YL]ACETATE; ETHYL[2,4 DIOXO 5 [4 (4 OXO 4H CHROMEN 2 YL)BENZYLIDENE] 1,3 THIAZOLIDINE 3YL]ACETATE; FLAVONYL 2,4 THIAZOLIDINEDIONE DERIVATIVE; GLIBENCLAMIDE; GLUCOSE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BIOLOGICAL ACTIVITY; CONTROLLED STUDY; DRUG INHIBITION; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; INSULIN LIKE ACTIVITY; INSULIN RELEASE; KNOEVENAGEL CONDENSATION; MALE; NONHUMAN; RAT;

ALDEHYDE REDUCTASE; ANIMALS; CELL LINE; GLUCOSE; HUMANS; HYPOGLYCEMIC AGENTS; INSULIN; KIDNEY; MALE; MICE; RATS; THIAZOLIDINEDIONES;

RATTUS;

EID: 47349110359     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2008.05.059     Document Type: Article

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