메뉴 건너뛰기




Volumn 56, Issue 12, 2008, Pages 4393-4398

Bioactivities of gossypol, 6-methoxygossypol, and 6,6′- dimethoxygossypol

Author keywords

Anticancer; Antioxidant; Cottonseed; Gossypol; Gossypol derivative; Trypanosome

Indexed keywords

6 METHOXY GOSSYPOL; 6-METHOXY GOSSYPOL; ANTINEOPLASTIC AGENT; ANTIOXIDANT; GOSSYPOL; NAPHTHALENE DERIVATIVE; PHENOL DERIVATIVE;

EID: 47349086746     PISSN: 00218561     EISSN: None     Source Type: Journal    
DOI: 10.1021/jf073297u     Document Type: Article
Times cited : (47)

References (39)
  • 1
    • 0016394036 scopus 로고
    • Gossypol: Antagonistic effect on toxicity of insecticides to Spodoptera littoralis
    • Abou-Donia, M. B.; Taman, F.; Bakery, N. M.; El-Sabae, A. H. Gossypol: Antagonistic effect on toxicity of insecticides to Spodoptera littoralis. Experientia 1974, 30, 1151-1152.
    • (1974) Experientia , vol.30 , pp. 1151-1152
    • Abou-Donia, M.B.1    Taman, F.2    Bakery, N.M.3    El-Sabae, A.H.4
  • 2
    • 0014107127 scopus 로고
    • Inhibitory effect of gossypol on microorganisms
    • Margalith, P. Inhibitory effect of gossypol on microorganisms. Appl. Microbiol. 1967, 15, 952-953.
    • (1967) Appl. Microbiol , vol.15 , pp. 952-953
    • Margalith, P.1
  • 3
    • 0018248639 scopus 로고
    • Gossypol, a new antifertility agent for males Chinese
    • Anonymous
    • Anonymous. Gossypol, a new antifertility agent for males Chinese Med. J. 1978, 4, 417-428.
    • (1978) Med. J , vol.4 , pp. 417-428
  • 4
    • 0018813694 scopus 로고
    • Gossypol as an oral contraceptive for men
    • Anonymous
    • Anonymous. Gossypol as an oral contraceptive for men J. Med. Soc. N. J. 1980, 77, 50.
    • (1980) J. Med. Soc. N. J , vol.77 , pp. 50
  • 6
    • 33745603202 scopus 로고    scopus 로고
    • Molecular mechanisms of (-)-gossypol-induced apoptosis in human prostate cancer cells
    • Huang, Y. W.; Wang, L. S.; Chang, H. L.; Ye, W.; Dowd, M. K.; Wan, P. J.; Lin, Y. C. Molecular mechanisms of (-)-gossypol-induced apoptosis in human prostate cancer cells. Anticancer Res. 2006, 26, 1925-1933.
    • (2006) Anticancer Res , vol.26 , pp. 1925-1933
    • Huang, Y.W.1    Wang, L.S.2    Chang, H.L.3    Ye, W.4    Dowd, M.K.5    Wan, P.J.6    Lin, Y.C.7
  • 7
    • 0032763522 scopus 로고    scopus 로고
    • Gossypol induced apoptosis in the human promyelocytic leukemia cell line HL 60
    • Balci, A.; Sahin, F. I.; Ekmekci, A. Gossypol induced apoptosis in the human promyelocytic leukemia cell line HL 60. Tohoku J. Exp. Med. 1999, 189, 51-57.
    • (1999) Tohoku J. Exp. Med , vol.189 , pp. 51-57
    • Balci, A.1    Sahin, F.I.2    Ekmekci, A.3
  • 8
    • 0038682166 scopus 로고    scopus 로고
    • Molecular mechanism of gossypol-induced cell growth inhibition and cell death of HT-29 human colon carcinoma cells
    • Zhang, M.; Liu, H.; Guo, R.; Ling, Y.; Wu, X.; Li, B.; Roller, P. P.; Wang, S.; Yang, D. Molecular mechanism of gossypol-induced cell growth inhibition and cell death of HT-29 human colon carcinoma cells. Biochem. Pharmacol. 2003, 66, 93-103.
    • (2003) Biochem. Pharmacol , vol.66 , pp. 93-103
    • Zhang, M.1    Liu, H.2    Guo, R.3    Ling, Y.4    Wu, X.5    Li, B.6    Roller, P.P.7    Wang, S.8    Yang, D.9
  • 9
    • 0022899737 scopus 로고
    • Antiviral activities of gossypol and its derivatives against herpes simplex virus type II
    • Radloff, R. J.; Deck, L. M.; Royer, R. E.; Vander Jagt, D. L. Antiviral activities of gossypol and its derivatives against herpes simplex virus type II. Pharmacol. Res. Commun. 1986, 18, 1063-1073.
    • (1986) Pharmacol. Res. Commun , vol.18 , pp. 1063-1073
    • Radloff, R.J.1    Deck, L.M.2    Royer, R.E.3    Vander Jagt, D.L.4
  • 12
    • 0020898943 scopus 로고
    • Effect of gossypol upon motility and ultrastructure of Trypanosoma cruzi
    • Blanco, A.; Aoki, A.; Montamat, E. E.; Rovai, L. E. Effect of gossypol upon motility and ultrastructure of Trypanosoma cruzi. J. Protozool. 1983, 30, 648-651.
    • (1983) J. Protozool , vol.30 , pp. 648-651
    • Blanco, A.1    Aoki, A.2    Montamat, E.E.3    Rovai, L.E.4
  • 15
    • 49649135751 scopus 로고
    • Antimicrobial terpenoids of Gossypium: 6-Methoxygossypol and 6,6′- dimethoxygossypol
    • Stipanovic, R. D.; Bell, A. A.; Mace, M. E.; Howell, C. R. Antimicrobial terpenoids of Gossypium: 6-Methoxygossypol and 6,6′- dimethoxygossypol. Phytochemistry 1975, 14, 1077-1081.
    • (1975) Phytochemistry , vol.14 , pp. 1077-1081
    • Stipanovic, R.D.1    Bell, A.A.2    Mace, M.E.3    Howell, C.R.4
  • 16
    • 0030019021 scopus 로고    scopus 로고
    • Seed gossypol variation within Gossypium barbadense L. Cotton
    • Percy, R. G.; Calhoun, M. C.; Kim, H. L. Seed gossypol variation within Gossypium barbadense L. Cotton. Crop Sci. 1996, 36, 193-197.
    • (1996) Crop Sci , vol.36 , pp. 193-197
    • Percy, R.G.1    Calhoun, M.C.2    Kim, H.L.3
  • 17
    • 0025046346 scopus 로고
    • Antifertility actions of gossypol derivatives and analogues
    • Wang, W. H.; Yu, Z. H.; Cai, M.; Xu, X. M.; Wu, G. P. Antifertility actions of gossypol derivatives and analogues. Zhongguo Yao Li Xue Boo 1990, 11, 268-271.
    • (1990) Zhongguo Yao Li Xue Boo , vol.11 , pp. 268-271
    • Wang, W.H.1    Yu, Z.H.2    Cai, M.3    Xu, X.M.4    Wu, G.P.5
  • 18
    • 33744483821 scopus 로고    scopus 로고
    • Isolation of 6-methoxy gossypol and 6,6′-dimethoxy gossypol from Gossypium barbadense Sea Island cotton
    • Dowd, M. K.; Pelitire, S. M. Isolation of 6-methoxy gossypol and 6,6′-dimethoxy gossypol from Gossypium barbadense Sea Island cotton. J. Agric. Food Chem. 2006, 54, 3265-3270.
    • (2006) J. Agric. Food Chem , vol.54 , pp. 3265-3270
    • Dowd, M.K.1    Pelitire, S.M.2
  • 19
    • 0032086769 scopus 로고    scopus 로고
    • HPLC method for evaluation of the free radical-scavenging activity of foods by using 1,1-diphenyl-2-picrylhydrazyl
    • Yamaguchi, T.; Takamura, H.; Matoba, T.; Terao, J. HPLC method for evaluation of the free radical-scavenging activity of foods by using 1,1-diphenyl-2-picrylhydrazyl. Biosci. Biotechnol. Biochem. 1998, 62, 1201-1204.
    • (1998) Biosci. Biotechnol. Biochem , vol.62 , pp. 1201-1204
    • Yamaguchi, T.1    Takamura, H.2    Matoba, T.3    Terao, J.4
  • 20
    • 0037051525 scopus 로고    scopus 로고
    • Antioxidative activity and safety of the 50 ethanolic extract from red bean fermented by Bacillus subtilis IMR-NK1
    • Chung, Y. C.; Chang, C. T.; Chao, W. W.; Lin, C. F.; Chou, S. T. Antioxidative activity and safety of the 50 ethanolic extract from red bean fermented by Bacillus subtilis IMR-NK1. J. Agric. Food Chem. 2002, 50, 2454-2458.
    • (2002) J. Agric. Food Chem , vol.50 , pp. 2454-2458
    • Chung, Y.C.1    Chang, C.T.2    Chao, W.W.3    Lin, C.F.4    Chou, S.T.5
  • 21
    • 0034047551 scopus 로고    scopus 로고
    • Antioxidant and anti-tumor promoting activities of the methanol extract of heat-processed ginseng
    • Keum, Y. S.; Park, K. K.; Lee, J. M.; Chun, K. S.; Park, J. H.; Lee, S. K.; Kwon, H.; Surh, Y. J. Antioxidant and anti-tumor promoting activities of the methanol extract of heat-processed ginseng. Cancer Lett. 2000, 150, 41-48.
    • (2000) Cancer Lett , vol.150 , pp. 41-48
    • Keum, Y.S.1    Park, K.K.2    Lee, J.M.3    Chun, K.S.4    Park, J.H.5    Lee, S.K.6    Kwon, H.7    Surh, Y.J.8
  • 24
    • 0024948840 scopus 로고
    • Continuous cultivation of Trypanosoma brucei blood stream forms in a medium containing a low concentration of serum protein without feeder cell layers
    • Hirumi, H.; Hirumi, K. Continuous cultivation of Trypanosoma brucei blood stream forms in a medium containing a low concentration of serum protein without feeder cell layers. J. Parasitol. 1989, 75, 985-989.
    • (1989) J. Parasitol , vol.75 , pp. 985-989
    • Hirumi, H.1    Hirumi, K.2
  • 25
    • 33747596165 scopus 로고    scopus 로고
    • Oxidative damage of DNA induced by the cytochrome c and hydrogen peroxide system
    • Kim, N. H.; Kang, J. H. Oxidative damage of DNA induced by the cytochrome c and hydrogen peroxide system. J. Biochem. Mol. Biol. 2006, 39, 452-456.
    • (2006) J. Biochem. Mol. Biol , vol.39 , pp. 452-456
    • Kim, N.H.1    Kang, J.H.2
  • 26
    • 0021355584 scopus 로고
    • Effect of gossyopl on DNA synthesis and cell cycle progression of mammalian cells in vitro
    • Wang, Y.; Rao, P. N. Effect of gossyopl on DNA synthesis and cell cycle progression of mammalian cells in vitro. Cancer Res. 1984, 44, 35-36.
    • (1984) Cancer Res , vol.44 , pp. 35-36
    • Wang, Y.1    Rao, P.N.2
  • 27
    • 0024561356 scopus 로고
    • Antiproliferative effect of gossypol and its optical isomers on human reproductive cancer cell lines
    • Band, V.; Hoffer, A. P.; Band, H.; Rhinehardt, A. E.; Knapp, R. C.; Madin, S. A.; Anderson, D. J. Antiproliferative effect of gossypol and its optical isomers on human reproductive cancer cell lines. Gynecol. Oncol. 1989, 32, 273-277.
    • (1989) Gynecol. Oncol , vol.32 , pp. 273-277
    • Band, V.1    Hoffer, A.P.2    Band, H.3    Rhinehardt, A.E.4    Knapp, R.C.5    Madin, S.A.6    Anderson, D.J.7
  • 28
    • 0023722609 scopus 로고
    • Effects of gossypol on the antioxidant defense system of the rat testis
    • Bender, H. S.; Derolf, S. Z.; Misra, H. P. Effects of gossypol on the antioxidant defense system of the rat testis. Arch. Androl. 1988, 21, 59-70.
    • (1988) Arch. Androl , vol.21 , pp. 59-70
    • Bender, H.S.1    Derolf, S.Z.2    Misra, H.P.3
  • 30
    • 0036244595 scopus 로고    scopus 로고
    • The (-)-enantiomer of gossypol possesses higher anticancer potency than racemic gossypol in human breast cancer
    • Liu, S.; Kulp, S. K.; Sugimoto, Y.; Jiang, J.; Chang, H. L.; Dowd, M. K.; Wan, P.; Lin, Y. C. The (-)-enantiomer of gossypol possesses higher anticancer potency than racemic gossypol in human breast cancer. Anticancer Res. 2002, 22, 33-38.
    • (2002) Anticancer Res , vol.22 , pp. 33-38
    • Liu, S.1    Kulp, S.K.2    Sugimoto, Y.3    Jiang, J.4    Chang, H.L.5    Dowd, M.K.6    Wan, P.7    Lin, Y.C.8
  • 31
    • 1442301661 scopus 로고    scopus 로고
    • The inhibitory effects of gossypol on human prostate cancer cells-PC3 are associated with transforming growth factor betal (TGFbeta1) signal transduction pathway
    • Jiang, J.; Sugimoto, Y.; Liu, S.; Chang, H. L.; Park, K. Y.; Kulp, S. K.; Lin, Y. C. The inhibitory effects of gossypol on human prostate cancer cells-PC3 are associated with transforming growth factor betal (TGFbeta1) signal transduction pathway. Anticancer Res. 2004, 24, 91-100.
    • (2004) Anticancer Res , vol.24 , pp. 91-100
    • Jiang, J.1    Sugimoto, Y.2    Liu, S.3    Chang, H.L.4    Park, K.Y.5    Kulp, S.K.6    Lin, Y.C.7
  • 32
    • 0033822231 scopus 로고    scopus 로고
    • Dao, V. T.; Gaspard, C.; Mayer, M.; Werner, G. H.; Nguyen, S. N.; Michelot, R. J. Synthesis and cytotoxicity of gossypol related compounds. Eur. J. Med. Chem. 2000, 35, 805-813.
    • Dao, V. T.; Gaspard, C.; Mayer, M.; Werner, G. H.; Nguyen, S. N.; Michelot, R. J. Synthesis and cytotoxicity of gossypol related compounds. Eur. J. Med. Chem. 2000, 35, 805-813.
  • 34
    • 0028925384 scopus 로고
    • Comparison of the antiviral activities of 3′-azido-3′-deoxythymidine (AZT) and gossylic iminolactone (GIL) against clinical isolates of HIV-1
    • Royer, R. E.; Mills, R. G.; Young, S. A.; Vander Jagt, D. L. Comparison of the antiviral activities of 3′-azido-3′-deoxythymidine (AZT) and gossylic iminolactone (GIL) against clinical isolates of HIV-1. Pharmacol. Res. 1995, 31, 49-52.
    • (1995) Pharmacol. Res , vol.31 , pp. 49-52
    • Royer, R.E.1    Mills, R.G.2    Young, S.A.3    Vander Jagt, D.L.4
  • 35
    • 31444454299 scopus 로고    scopus 로고
    • DPPH radical scavenging reaction of hydroxy- and methoxychalcones
    • Nishida, J.; Kawabata, J. DPPH radical scavenging reaction of hydroxy- and methoxychalcones. Biosci. Biotechnol. Biochem. 2006, 70, 193-202.
    • (2006) Biosci. Biotechnol. Biochem , vol.70 , pp. 193-202
    • Nishida, J.1    Kawabata, J.2
  • 36
    • 47349094867 scopus 로고    scopus 로고
    • Food and Drug Administration, 1974. Food Drug Cosmetic Law. 56, 518.94, 172.894 1974.
    • Food and Drug Administration, 1974. Food Drug Cosmetic Law. 56, 518.94, 172.894 1974.
  • 37
    • 47349093027 scopus 로고    scopus 로고
    • Protein Advisory Group of the United Nations PAG Guideline No.4, FAO/WHO/UNICEF, New York. Preparation of Edible Cottonseed Protein Concentrate, 1972.
    • Protein Advisory Group of the United Nations PAG Guideline No.4, FAO/WHO/UNICEF, New York. Preparation of Edible Cottonseed Protein Concentrate, 1972.
  • 39
    • 0024369592 scopus 로고
    • Feeder layer-free in vitro assay for screening antitrypanosomal compounds against Trypanosoma brucei brucei and T. b. evansi
    • Kaminsky, R.; Zweygarth, E. Feeder layer-free in vitro assay for screening antitrypanosomal compounds against Trypanosoma brucei brucei and T. b. evansi. Antimicrob. Agents Chemother. 1989, 33, 881-885.
    • (1989) Antimicrob. Agents Chemother , vol.33 , pp. 881-885
    • Kaminsky, R.1    Zweygarth, E.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.