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Volumn 46, Issue 7, 2008, Pages 987-989

Easy detection of 5,10-methylenetetrahydrofolate reductase 1298A/C genotype by mutagenically separated PCR assay

Author keywords

Genotyping; MTHFR; Mutagenically separated PCR; Single nucleotide polymorphism

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2);

EID: 47349084389     PISSN: 14346621     EISSN: 14374331     Source Type: Journal    
DOI: 10.1515/CCLM.2008.184     Document Type: Article
Times cited : (2)

References (16)
  • 1
    • 0035552975 scopus 로고    scopus 로고
    • Polymorphisms in the methylenetetrahydrofolate reductase gene: Clinical consequences
    • Schwahn B, Rozen R. Polymorphisms in the methylenetetrahydrofolate reductase gene: clinical consequences. Am J Pharmacogenom 2001;1:189-201.
    • (2001) Am J Pharmacogenom , vol.1 , pp. 189-201
    • Schwahn, B.1    Rozen, R.2
  • 2
    • 1642586763 scopus 로고    scopus 로고
    • Molecular biology of 5,10-methylenetetrahydrofolate reductase
    • Födinger M, Hörl WH, Sunder-Plassmann G. Molecular biology of 5,10-methylenetetrahydrofolate reductase. J Nephrol 2000;13:20-33.
    • (2000) J Nephrol , vol.13 , pp. 20-33
    • Födinger, M.1    Hörl, W.H.2    Sunder-Plassmann, G.3
  • 3
    • 0034743914 scopus 로고    scopus 로고
    • The 1298A→C polymorphism in methylenetetrahydrofolate reductase (MTHFR): In vitro expression and association with homocysteine
    • Weisberg IS, Jacques PF, Selhub J, Bostom AG, Chen Z, Curtis Ellison R, et al. The 1298A→C polymorphism in methylenetetrahydrofolate reductase (MTHFR): in vitro expression and association with homocysteine. Atherosclerosis 2001;156:409-15.
    • (2001) Atherosclerosis , vol.156 , pp. 409-415
    • Weisberg, I.S.1    Jacques, P.F.2    Selhub, J.3    Bostom, A.G.4    Chen, Z.5    Curtis Ellison, R.6
  • 4
    • 36549006514 scopus 로고    scopus 로고
    • MTHFR genetic polymorphism as a risk factor in Egyptian mothers with Down syndrome children
    • Meguid NA, Dardir AA, Khass M, Hossieny LE, Ezzat A, Awady MK. MTHFR genetic polymorphism as a risk factor in Egyptian mothers with Down syndrome children. Dis Markers 2008;24:19-26.
    • (2008) Dis Markers , vol.24 , pp. 19-26
    • Meguid, N.A.1    Dardir, A.A.2    Khass, M.3    Hossieny, L.E.4    Ezzat, A.5    Awady, M.K.6
  • 5
    • 38849089220 scopus 로고    scopus 로고
    • The association of gastric cancer risk with plasma folate, cobalamin, and methylenetetrahydrofolate reductase polymorphisms in the European prospective investigation into cancer and nutrition
    • Vollset SE, Igland J, Jenab M, Fredriksen A, Meyer K, Eussen S, et al. The association of gastric cancer risk with plasma folate, cobalamin, and methylenetetrahydrofolate reductase polymorphisms in the European prospective investigation into cancer and nutrition. Cancer Epidemiol Biomarkers Prev 2007;16:2416-24.
    • (2007) Cancer Epidemiol Biomarkers Prev , vol.16 , pp. 2416-2424
    • Vollset, S.E.1    Igland, J.2    Jenab, M.3    Fredriksen, A.4    Meyer, K.5    Eussen, S.6
  • 6
    • 33846816918 scopus 로고    scopus 로고
    • Dietary intake of folate and co-factors in folate metabolism, MTHFR polymorphisms, and reduced rectal cancer
    • Murtaugh MA, Curtin K, Sweeney C, Wolff RK, Holubkov R, Caan BJ, et al. Dietary intake of folate and co-factors in folate metabolism, MTHFR polymorphisms, and reduced rectal cancer. Cancer Causes Control 2007;18:153-63.
    • (2007) Cancer Causes Control , vol.18 , pp. 153-163
    • Murtaugh, M.A.1    Curtin, K.2    Sweeney, C.3    Wolff, R.K.4    Holubkov, R.5    Caan, B.J.6
  • 7
    • 33750491268 scopus 로고    scopus 로고
    • Association between the MTHFR A1298C polymorphism and increased risk of acute myeloid leukemia in Brazilian children
    • da Costa Ramos FJ, Cartaxo Muniz MT, Silva VC, Araújo M, Leite EP, Freitas EM, et al. Association between the MTHFR A1298C polymorphism and increased risk of acute myeloid leukemia in Brazilian children. Leuk Lymphoma 2006;47:2070-5.
    • (2006) Leuk Lymphoma , vol.47 , pp. 2070-2075
    • da Costa Ramos, F.J.1    Cartaxo Muniz, M.T.2    Silva, V.C.3    Araújo, M.4    Leite, E.P.5    Freitas, E.M.6
  • 8
    • 31544481440 scopus 로고    scopus 로고
    • Associations between 5,10-methylenetetrahydrofolate reductase codon 677 and 1298 genetic polymorphisms and environmental factors with reference to susceptibility to colorectal cancer: A case-control study in an Indian population
    • Wang J, Gajalakshmi V, Jiang J, Kuriki K, Suzuki S, Nagaya T, et al. Associations between 5,10-methylenetetrahydrofolate reductase codon 677 and 1298 genetic polymorphisms and environmental factors with reference to susceptibility to colorectal cancer: a case-control study in an Indian population. Int J Cancer 2006;118:991-7.
    • (2006) Int J Cancer , vol.118 , pp. 991-997
    • Wang, J.1    Gajalakshmi, V.2    Jiang, J.3    Kuriki, K.4    Suzuki, S.5    Nagaya, T.6
  • 9
    • 34547616313 scopus 로고    scopus 로고
    • MTHFR 677 CT/MTHFR 1298 CC genotypes are associated with increased risk of hypertension in Indians
    • Markan S, Sachdeva M, Sehrawat BS, Kumari S, Jain S, Khullar M. MTHFR 677 CT/MTHFR 1298 CC genotypes are associated with increased risk of hypertension in Indians. Mol Cell Biochem 2007;302:125-31.
    • (2007) Mol Cell Biochem , vol.302 , pp. 125-131
    • Markan, S.1    Sachdeva, M.2    Sehrawat, B.S.3    Kumari, S.4    Jain, S.5    Khullar, M.6
  • 11
    • 34548798662 scopus 로고    scopus 로고
    • GSTP1 and MTHFR polymorphisms are related with toxicity in breast cancer adjuvant anthracycline-based treatment
    • Zárate R, González-Santigo S, de la Haba J, Bandres E, Morales R, Salgado J, et al. GSTP1 and MTHFR polymorphisms are related with toxicity in breast cancer adjuvant anthracycline-based treatment. Curr Drug Metab 2007;8:481-6.
    • (2007) Curr Drug Metab , vol.8 , pp. 481-486
    • Zárate, R.1    González-Santigo, S.2    de la Haba, J.3    Bandres, E.4    Morales, R.5    Salgado, J.6
  • 12
    • 34548059490 scopus 로고    scopus 로고
    • A1298C polymorphism of the MTHFR gene and neural tube defects in the state of Yucatan, Mexico. Birth Defects Res A Clin Mol
    • Gonzalez-Herrera L, Castillo-Zapata I, Garcia-Escalante G, Pinto-Escalante D. A1298C polymorphism of the MTHFR gene and neural tube defects in the state of Yucatan, Mexico. Birth Defects Res A Clin Mol Teratol 2007;79:622-6.
    • (2007) Teratol , vol.79 , pp. 622-626
    • Gonzalez-Herrera, L.1    Castillo-Zapata, I.2    Garcia-Escalante, G.3    Pinto-Escalante, D.4
  • 13
    • 0031971515 scopus 로고    scopus 로고
    • A second common mutation in the methylenetetrahydrofolate reductase gene: An additional risk factor for neural-tube defects?
    • van der Put NM, Gabreëls F, Stevens EM, Smeitink JA, Trijbels FJ, Eskes TK, et al. A second common mutation in the methylenetetrahydrofolate reductase gene: an additional risk factor for neural-tube defects? Am J Hum Genet 1998;62:1044-51.
    • (1998) Am J Hum Genet , vol.62 , pp. 1044-1051
    • van der Put, N.M.1    Gabreëls, F.2    Stevens, E.M.3    Smeitink, J.A.4    Trijbels, F.J.5    Eskes, T.K.6
  • 14
    • 19944366586 scopus 로고    scopus 로고
    • Methylenetetrahydrofolate reductase C677T and A1298C polymorphisms and colorectal cancer: The Fukuoka Colorectal Cancer Study
    • Yin G, Kono S, Toyomura K, Hagiwara T, Nagano J, Mizoue T, et al. Methylenetetrahydrofolate reductase C677T and A1298C polymorphisms and colorectal cancer: the Fukuoka Colorectal Cancer Study. Cancer Sci 2004;95:908-13.
    • (2004) Cancer Sci , vol.95 , pp. 908-913
    • Yin, G.1    Kono, S.2    Toyomura, K.3    Hagiwara, T.4    Nagano, J.5    Mizoue, T.6
  • 15
    • 0031687887 scopus 로고    scopus 로고
    • A second genetic polymorphism in methylenetetrahydrofolate reductase (MTHFR) associated with decreased enzyme activity
    • Weisberg I, Tran P, Christensen B, Sibani S, Rozen R. A second genetic polymorphism in methylenetetrahydrofolate reductase (MTHFR) associated with decreased enzyme activity. Mol Gen Metab 1998;64:169-72.
    • (1998) Mol Gen Metab , vol.64 , pp. 169-172
    • Weisberg, I.1    Tran, P.2    Christensen, B.3    Sibani, S.4    Rozen, R.5
  • 16
    • 0027259126 scopus 로고
    • Mutagenically separated PCR (MS-PCR): A highly specific one step procedure for easy mutation detection
    • Rust S, Funke H, Assmann G. Mutagenically separated PCR (MS-PCR): a highly specific one step procedure for easy mutation detection. Nucleic Acids Res 1993;21:3623-9.
    • (1993) Nucleic Acids Res , vol.21 , pp. 3623-3629
    • Rust, S.1    Funke, H.2    Assmann, G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.